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Volume 19, Issue 2
Displaying 1-11 of 11 articles from this issue
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IN PARTICULAR, ON THE VIRUS-LIKE PARTICLES DETECTED WITHIN THE NUCLEUSSHINSHI NODA1972 Volume 19 Issue 2 Pages 61-79
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe general concept of pathogenesis of nephroblastoma (Wilms's tumor) indicates at present that the origin of the tumor is the metanephric blastema, however, the present electronmicroscopic findings suggest a necessity to suppose a viral factor for carcinogenesis. In this report, the light- and electron-microscopic studies were made on the tissue or cells of nephroblastoma extirpated surgically. The tumor cells revealed light-microscopically the tubular appearance resembling the renal tubules. The nucleus of the epithelial cell of the tubules in question contained both the rod-like structures of 250-350 Å in width and the virus-like particles of the same dimension, the globular particles being otherwise in part arranged in a mode of crystal. There was also the matrix of reticular structures supposed to be precursors of the particles. In addition, the morphological change and feature of the rodlike structure and the particles were correlatively investigated with a distribution pattern of chromatin which may be the functional site of the formation of these structures and is chemically composed of deoxyribonucleic protein. Moerover, the comparative discussion was made between intranuclear virus particles reported so far and the structures resembling the virus particles observable in the nuclei of the normal and cancer cells. The histogenesis of nephroblastoma (Wilms's tumor) was proposed by summarizing these experimental facts and hypothetical concepts.View full abstractDownload PDF (23134K) -
CASE REPORTHIROYOSHI MIZOTE, SEITARO SAKAI, WATARU OGO, HIDEYA KAMEI, HIROMICHI Y ...1972 Volume 19 Issue 2 Pages 81-83
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA 3-hour-old full-term male was admitted with complaints of dyspnea, cyanosis and vomiting which might result from abdominal distension, and congenital hydronephrosis or mesenterial cyst were clinically diagnosed, and emergency operation was carried out and congenital hydronephrosis was confirmed on operation. In a review of the literature, there has been no similar case in which hydronephrosis occupied the abdomen causing dyspnea and disturbance of passage of the digestive tract.View full abstractDownload PDF (3479K) -
FUMIO YAMASHITA, HIDEAKI ARIHIRO1972 Volume 19 Issue 2 Pages 85-87
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe blood ketones, glucose and plasma free fatty acid were analyzed along the course of 12 cases of infantile diarrhea with dehydration. Elevated blood ketones and plasma free fatty acid with variable blood glucose levels were observed at the acute stage of diarrhea except 3 cases. The data suggested that the elevated blood ketones with increased lipolysis might contribute to the metabolic acidosis in infantile diarrhea.View full abstractDownload PDF (310K) -
FUMIO YAMASHITA, HIDEAKI ARIHIRO, ATSUSHI NAKAO, TOKURO NAGAYAMA1972 Volume 19 Issue 2 Pages 89-93
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe response of blood glucose, ketones and plasma FFA to epinephrine injection (0.01 ml/kg Body weight of 1 : 1000 solution, S. C.) in 17 cases of periodic vomiting was tested when they had no episodes. The determinations were perof ormed at the 5 hours' fast since the breakfast, 30 minutes and 60 minutes after the injection. The fasting levels of plasma FFA and blood ketones revealed higher values and the higher rize of plasma FFA to epinephrine were observed compared with 7 control cases. The data suggested that they might have increased lipolysic tendency even in apparently well condition, or might show more sensitive lipolysis to epinephrine.View full abstractDownload PDF (1070K) -
TATSUO SHIMADA, MIZUHO NONAKA, NORIHARU AMAGASE1972 Volume 19 Issue 2 Pages 95-104
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe pars intermedia of the pituitary body in the adult male monkey (Macacus f uscatus) was investigated by means of electron microscope. The pars intermedia contains glandular cells, agranular cells, and a great number of unmyelinated nerve fibers. The glandular cells are further composed of three types of cells : Type I contains numerous large secretory granules (about 2500 - 4000 Å in diameter) with variable electron density, and are most dominant in number. Type II possesses smaller dense secretory granules (about 2000 - 2200 Å) and the well-developed rough-surfaced endoplasmic reticulum. Type III contains the smallest dense secretory granules (about 1300- 1500 Å). Both types, II and III, are quite small in number. Agranular cells have no granules suggestive of secretion, and may serve as the supporting cell. In the monkey pars intermedia, three types of nerve endings can be distinguished ; (I) nerve endings only containing synaptic vesicles of about 500 Å, (II) nerve endings with synaptic vesicles and large dense-cored vesicles (large granular vesicles), about 900 Å, and (III) nerve endings containing synaptic vesicles and elementary granules of neurosecretory substance, about 1500 Å. The results may indicate that the pays intermedia of the adult male monkey is still active in secretory function.View full abstractDownload PDF (12557K) -
I. THE RELATIONSHIP BETWEEN INTRADERMAL REACTION AND HEMAGGLUTINATIONSHIN-ICHI YAMANOUCHI1972 Volume 19 Issue 2 Pages 105-112
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSAn intradermal reaction is induced by the parasitization with f ilariae. The antibody against these parasites can be detected by the hemagglutination (HA) test using erythrocytes treated with tannic acid. The present experiments were carried out in order to clarify the relationship between the intradermal reaction and the HA test in canine filariasis and Bancroft's filariasis. As a result, no parallel relationship was observed between the intensity of the intradermal reaction and the titer as determined by the HA test. It was presumed that the relationship among the appearance of microf ilariae, the intradermal reaction, and the HA test might be influenced by the differences in the antibody system on the part of the host concerned.View full abstractDownload PDF (859K) -
II. THE RELATIONSHIP BETWEEN INTRADERMAL REACTION AND IMMUNOGLOBULINSHIN-ICHI YAMANOUCHI1972 Volume 19 Issue 2 Pages 113-116
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSImmunoglobulin was separated from the serum of human patients positive for microfilariae (Mf) of Wuchereria bancrofti by using the DEAE cellulose-columnchromatography method. Then it was fractionated to obtain the IgG and IgM antibodies. The hemagglutination (HA) test was carried out with both types of antibodies. As a result, we found no marked difference in the results of the HA test, regardless of the presence or absence of Mf in the body, between the two fractions represented by the IgG and IgM antibodies.View full abstractDownload PDF (442K) -
III. ANTIGENIC SUBSTANCE IN THE URINE OF DOGS INFECTED WITH DIROFILARIA IMMITISSHIN-ICHI YAMANOUCHI1972 Volume 19 Issue 2 Pages 117-121
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThrough this series of experiments (Intradermal reactions, HA test, Immunoglobulin test, and Okabe's urine precipitin test), the last one (Okabe's method of the urine precipitin test) has been found to be the most excellent and the most practicable in many respects for the immunological diagnosis of parasitologic diseases such as filariasis. Concerning the experimental materials, most of them are easily obtained in a short period of time except for the anti-D. immitis rabbit serum, and it has been found that the experimental results of these reactions can be kept to some extent for a rather long time without using any preservatives. The details of the chemical and biochemical nature of the antigenic substance are yet unknown, so further investigation of it is surely needed.View full abstractDownload PDF (1764K) -
TOSHIHIRO HIDAKA, ISAMU MATSUMOTO1972 Volume 19 Issue 2 Pages 123-126
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe present paper reported a modification of the assay method for evaluating tyrosine hydroxylation described by Nagatsu, Levitt and Udenfriend. The procedure excluded adsorption step of 3H-tyrosine and 3H-dopa to Dowex or charcoal adsorbent for removal of 3H-water, and following elution step from the adsorbent. The radioactivity of 3H-tyrosine remaining in the reaction mixture or 3H-water converted from 3H-tyrosine was easily measured with this procedure without any skilful technique. It is needless to say that this method will give more satisfactory results if aliquot of the mixture is accurately transf erect in quantity to a scintillation vial.View full abstractDownload PDF (372K) -
TERUYUKI NAKASHIMA, AKIRA TANIMURA, HIDEO YAMAMOTO, SUSUMU YAMASAKI1972 Volume 19 Issue 2 Pages 127-131
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESS24 years old Japanese female who had a ruptured aneurysm of splenic artery was reported with the review of literatures in Japan. Since 1911, 22 cases including our cases were reported. 42% of them was congenital, and female was predominantly affected (_??_ : _??_=3 : 1). Clinical data in this case was not available because of her sudden death. Microscopically some part of the splenic aneurysm lost the muscle layer of the media and was replaced with fibrosis. It was concluded that this case would be congenital because of its microscopic findings and splenomegaly which had been found 11 years ago before death.View full abstractDownload PDF (2263K) -
ITSUKO USHIJIMA, KENICHI NAKAMURA, KIMINORI TSUCHIYA, KYOZO KOKETSU1972 Volume 19 Issue 2 Pages 133-136
Published: March 25, 1972
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe effect of chlorpromazine on the contents of dopamine in rat's brains has been studied in order to clarify the cause of the chlorpromazine-induced Parkinsonism. A significant reduction of the contents of dopamine and also noradrenaline in rat's brains was noted one hour after a single i. p. injection of chlorpromazine. The significance of this result was discussed in connection with the therapeutic effect of L-dopa on the pharmacological Parkinsonism.View full abstractDownload PDF (456K)
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