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Volume 28, Issue 1
Displaying 1-15 of 15 articles from this issue
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RYOHEI OGURA, MASAFUMI MURAKATA, TOSHIRO SAKATA, RYOICHI CHIBA1981 Volume 28 Issue 1 Pages 1-8
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSMitochondria prepared from rat liver were incubated with ultraviolet light exposed methyl linoleate. By the method of using anisotropic inhibitor (ethidium bromide), the negative charge of outer-side of inner membrane of mitochondria energized was found to decrease following incubation. The disorders of respiratory responses of mitochondria affected with UV exposed methyl linoleate was related with the membrane damage. The combination use of superoxide dismutase could restore the membrane disorders induced by UV exposed methyl Linoleate. Liposome form was essential for res-toring membrane damages. However, free enzyme (no liposome form) had no effect on alleviating membrane disorders. The possibility of using superoxide dismutase (liposome form) was suggested for preventing cellular damage induced by lipid peroxidation.View full abstractDownload PDF (1912K) -
MASANOBU CHINAMI, KUOJI OKAMOTO, TOSHI KATO, RYOHEI OGURA1981 Volume 28 Issue 1 Pages 9-13
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe reduction of ferricytochrome c with adriamycin in phospate buffered saline (pH 7.4) and alkaline solution was obsereved spectrophoto-metrically. The reduction increased gradually with time of incubation, and decreased with the addition of superoxide dismutase. The semiquinone radical derived from adriamycin was detected by electron spin resonance spectrometer. Superoxide production by analogous compounds of adriamycin was examined. The cytotoxicity caused by anthraquinone antibiotics is discussed on the basis of molecular structure.View full abstractDownload PDF (3153K) -
An Autopsy CaseATSUO JIMI, TOMOKI ARITAKA, KYUICHI TANIKAWA, MASAYOSHI KAGE, MASAMICH ...1981 Volume 28 Issue 1 Pages 15-21
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA 27-year-old man with decompensated liver cirrhosis developed clinical characteristics of peritonitis, i. e. abrupt onset of fever, chills, abdominal pain with rebound tenderness and absent bowel sound, hypotension and leukocytosis. The patient expired despite vigorous antibiotic interfusion. An autopsy showed liver cirrhosis, splenomegaly and localized colitis. It was our speculation that weakened local resistance of the intestinal mucosa due to colitis may have led to the invasion of the peritoneal cavity by the enteric bacteria, serratia marcescens.View full abstractDownload PDF (4798K) -
MITSUAKI YOSHIZUKA, YASUHIRO KATSUME, SUNAO FUJIMOTO, YOSHIHIRO OGOH1981 Volume 28 Issue 1 Pages 23-27
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSDynamic changes of rat corneal epithelium and stroma after alkali burning were observed with the electron microscope. The neovascularization process in the stroma was almost the same as that observed after burning by heat. Reversible changes of the epithelial cells occurred throughout the course of wound healing. Approximately 10 days after burning, cells in deeper layers of the epithelium showed temporary changes such as increased in number of mitochondria and formation of lamellar cytoplasmic infoldings. These changes gradually disappeared while the reconstruction of regular arrangement of the collagen lamellae in the stroma was established. As it is widely accepted that such iofoldings play a role in active transport, dynamic changes of the epithelial cells in the present study indicate that reabsorption of the corneal edema is accomplished by both the corneal endothelium and the corneal epithelium.View full abstractDownload PDF (5214K) -
Case Report and Review of the LiteratureNOBUYUKI MIYOSHI, TAKUROU YAMASHITA, NOBUYUKI YOSHITAKE, SHINSHI NODA, ...1981 Volume 28 Issue 1 Pages 29-33
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA case of neonatal testicular infarction diagnosed five days after birth was described, and a brief review was made on 49 cases of testicular infarction and torsion reported in Japan.View full abstractDownload PDF (2638K) -
SUMIO ARAKI1981 Volume 28 Issue 1 Pages 35-43
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe influence of various extrinsic hormones was observed by using the clipping method to imbed and fix chemical carcinogens in the ovarian parenchyma. Among the hormones used, ACH and estrogen appeared to accelerate tumor growth. Although the incidence of solid tumors showed little difference among the test groups by the 20 th week, the incidence increased to 90% by the 40 th week in the ACH group. In hormone-given groups, incidence of tumors was low until the 20 th week, particularly in the androgen and progesteron groups. After that point the incidence of tumors incerased more in the hormone-given groups than in the control group. The estrogen group had the highest total incidence of cystic tumor, when compared with the control. The process of generating adenocarcinoma and sarcoma was fundamentally similar in the treated groups and the control. However, the time of appearance of tumors is the hormone-traced groups, except in the ACH group, differed from the control, particularly in the estrogen group.View full abstractDownload PDF (6195K) -
MICHIAKI YAKUSHIJI, MASASHI IMAMURA, RYUTA MASUMOTO, TOSHI KATO1981 Volume 28 Issue 1 Pages 45-52
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSIn a cohort of female rats, ovaries were transplanted to the spleens in order to observe over time the morphological changes of the transplanted ovary and to study the influence of gonadotropin on tumor development. The tumors which developed were morphologically grouped into granulosa cell tumors and theca cell tumors. Histologically, the former is generated from residual granulosa cells. It was presumed that tumor development requires hyper-gonadotropin and that FSH plays an important role.View full abstractDownload PDF (6221K) -
MASAYUKI HAMADA, YUKIHIKO YASUDA, SHINICHI NAKAYAMA, SHIGERU KIKUCHI, ...1981 Volume 28 Issue 1 Pages 53-61
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSTransverse spread of esophageal cancer is a significant prognostic factor equal to the influence of location and length on esophagogram. To examine extraluminal spread of tumors, we studied CT evaluation of the diagnosis and the treatment planning in esophageal cancer. In all 25 patients (100%), CT demonstrated a mass in the surrounding structures. In patients with cancer of the middle third of the esophagus displacement of trachea, aorta and left main bronchus were clearly detected by CT. There were also three patients with complications of esophagobronchial and esophagomediastinal fistulae after radiotherapy. In these cases, it was important to give palliative radiotherapy with decreased total dose. We believe that CT examination is a useful adjunct in the diagnosis of transverse extent of advanced esophageal cancer and for the treatment planning of irradiation in these cases.View full abstractDownload PDF (9830K) -
EIJI YANO1981 Volume 28 Issue 1 Pages 63-77
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThis study examined the influence of corticosteroids and ACTH on the brain of patients with nephrotic syndrome and infantile spasms by means of cranial computed tomography (CCT).CSF-space/intracranial space (C/I) ratio was used as a parameter of ap-parent cerebral atrophic findings, that is, the enlargement of the ventricles and the subarachnoid space. C/I ratio was calculated by computer processing of CCT at the level of the 3 rd and lateral ventricles. This is the first report in which computer processing is applied to the evaluation of CCT findings to study the effects of steroids and ACTH on the brain.Twelve of fifteen nephrotic patients showed abnormal C/I ratio after in-tensive steroid therapy. The average dose was 2147 mg of prednisolone for 3 weeks to 5 months. The average C/I ratio in the fifteen patients was 6.6 ± 3.9 % compared with 1.6 ± 0.8 % in 34 control individuals. The C/I ratio in the twelve patients with abnormally high values decreased to 2.6 ± 1.5% after reduction or withdrawal of steroids. The C/I ratio returned to normal in 9 of 12 patients at that time.In all patients treated with ACTH, C/I ratios increased significantly dur-ing ACTH therapy. In 8 patients with infantile spasms, C/I ratios were 5.1 ± 3.9 % before, 16.4 ± 7.8 % during, and 6.2 ± 3.3 % between 2 and 20 months after the withdrawal of therapy (0.25 to 0.5 mg/day of ACTH, IM., for 2 to 3 weeks).Although apparent cerebral atrophic findings were reversible in these patients, the data suggests that corticosteroid and ACTH can cause morphological changes of the cerebra in children as evaluated by CCT. The long-term and massive administration of steroids or ACTH should be minimized in children with growing cerebra, especially in neonates and infants.View full abstractDownload PDF (11894K) -
MINORU SHIGEMORI, MORIHISA SHIRAHAMA, TAKASHI TOKUTOMI, OSAMU NAKASHIM ...1981 Volume 28 Issue 1 Pages 79-82
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA case with fenestration of the bilateral extracranial vertebral arteries associated with cerebral aneurysm is reported. Angiographic demonstration of this anomaly of the vertebral artery is rare and reported almost by Japanese authors. A brief review of the literatures is made about this developmental anomaly.View full abstractDownload PDF (3765K) -
MINORU SHIGEMORI, MORIHISA SHIRAHAMA, TAKASHI TOKUTOMI, KUNITADA HARA, ...1981 Volume 28 Issue 1 Pages 83-86
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSAn interhemispheric subdural hematoma is uncommon although acute or chronic subdural hematoma are generally situated over the cerebral convexity. In this report, an interhem spheric subdural hematoma occuring in a patient with hemophilia B is described, with special reference to the characteristic clinical and computerized tomographic (CT) features.View full abstractDownload PDF (2041K) -
MINORU SHIGEMORI, MORIHISA SHIRAHAMA, TOMOYUKI KAWABA, TAKASHI TOKUTOM ...1981 Volume 28 Issue 1 Pages 87-89
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA case of cerebral aneurysm arising from the top of the basilar artery associated with an unusual anomaly of the middle cerebral artery termed an accessory middle cerebral artery or duplication of the middle cerebral artery is reported. A brief review of the literature about this vascular anomaly is also presented.View full abstractDownload PDF (2321K) -
A Case ReportTAKASHI HAYASHI, AKIRA ISHIBASHI, TAKEO HASHIMOTO, SHINKEN KURAMOTO1981 Volume 28 Issue 1 Pages 91-94
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe authors encountered a case of a rare sized huge congenital angioma of the sclap and cured it by total removal.A two-month-old male infant was born at full term by spontaneous vaginal delivery. A tumor the size of an adult's fist was recognized at the left temporal region. Selective external carotid arteriogram revealed four main feeders: namely occipital artery, frontal branch and parietal branch of superficial temporal artery, and posterior auricular artery. The main drainers were occipital vein and superficial temporal vein. At operation, this tumor was easily stripped from galea and was noted to have a capsule. While the feeders were being tied off and sectioned, the tumor rapidly reduced in size. Then, after ligation and sectioning of the occipital vein and superficial temporal vein as drainers, the tumor was removed in its original form.In the histological examination of this tumor, it was observed that inner layer of the epithelial tissue was almost evenly filled with capillary, thus, providing a diagnosis of capillary angioma.View full abstractDownload PDF (4040K) -
YASUKO KOHNO, MASATOSHI TANAKA, RYOICHI NAKAGAWA, YOSHISHIGE IDA, KENI ...1981 Volume 28 Issue 1 Pages 95-98
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSDownload PDF (451K) -
TAKASHI HAYASHI, AKIRA ISHIBASHI, TAKEO HASHIMOTO, KOHICHI EGAMI, SHIN ...1981 Volume 28 Issue 1 Pages 99-101
Published: August 25, 1981
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSDownload PDF (2113K)
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