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Volume 34, Issue 3
Displaying 1-7 of 7 articles from this issue
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RYUJI YOKOYAMA, HIROO IZUCHI, SHOJI KAWAHARA, HIRONORI TAMURA, MASAHIR ...1987 Volume 34 Issue 3 Pages 97-105
Published: October 01, 1987
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSPhagocytosis of spermatozoa and latex beads by the modified Sertoli cells, which are epithelial cells lining the terminal segment of the seminiferous tubule and forming a plug-like structure in the terminal region of the segment, was observed in the rat with TEM. Degenerated spermatozoa could occasionally be found in the cytoplasm of the modified Sertoli cells in the terminal plug. At the tip of the plug in some terminal segments, luminal macrophages loaded with a cluster of phagocytosed spermatozoa were also observed. Latex beads injected into the lumen of the rete testis were taken up by the modified Sertoli cells through pseudopodium formation and were finally concentrated in the lysosomal bodies of these cells. In this account, the phagocytic ability of the modified Sertoli cells was established and the significance was briefly discussed.View full abstractDownload PDF (9128K) -
SHUNSUKE SUGITA, HIDEHO HIGASHI, SYOGORO NISHI1987 Volume 34 Issue 3 Pages 107-113
Published: October 01, 1987
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSFlunarizine, a Ca-antagonist, at a concentration of 1μM reversibly depressed Ca-dependent spikes without affecting the resting membrane properties of guinea-pig hippocampal neurons. Flunarizine (1μM) did not affect the EPSPs evoked by focal stimuli, but slightly reduced the duration of evoked IPSPs. When the neurons were superfused with high K+ (60-75 mM) solutions, the membrane potential was irreversibly reduced to approximately 0 mV. The cell deterioration could be prevented by the addition of Co2+ (2mM), a specific Ca2+ channel blocker, to the superfusing solution. Addition of flunarizine (1 μM) also prevented the high K+ induced deterioration. These results indicate that the blockade of voltage dependent Ca2+- influxes by flunarizine prevents the cell deterioration induced by K+-rich media.View full abstractDownload PDF (850K) -
NOBUO KAKU1987 Volume 34 Issue 3 Pages 115-117
Published: October 01, 1987
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA survey of liver trauma in Japan was carried out. Of 979 accumulated cases, 178 (18.2%) involved penetrating injuries and 801 (81.8%) involved blunt injuries. The total number of deaths was 190 and the overall mortality was 19.4% .View full abstractDownload PDF (226K) -
HIDEKI SAITSU, MASAMICHI KOJIRO, SATORU TANIWAKI, HIROAKI YOSHIDA, KOU ...1987 Volume 34 Issue 3 Pages 119-124
Published: October 01, 1987
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSAdriamycin-Lipiodol emulsion (ADR-LIP) was injected, percutaneously via a 20 gauge needle with ultrasonographic guidance, as part of the treatment of 4 patients with relatively small hepatocellular carcinoma (HCC). Lymph vessels extending from the tumor nodule to the abdominal lymph nodes were imaged immediately after the injection in 3 patients. Subsequent plain films of the abdomen and abdominal computed tomography demonstrated stagnant collections of ADR-LIP in the abdominal lymph nodes. Histologic examination of lymph nodes removed during partial hepatectomy or at autopsy in these cases revealed many large and small fat droplets, thought to be Lipiodol, as well as macrophages containing phagocytized lipid. Although lymphatic metastasis occur in HCC, these findings suggest that lymphatics may exist in HCC tissue during the relatively early stages of tumor growth.View full abstractDownload PDF (6110K) -
SEIZABURO KASHIWAGI, WATARU KAJIYAMA, JUN HAYASHI, HIDEYUKI NOMURA, HI ...1987 Volume 34 Issue 3 Pages 125-132
Published: October 01, 1987
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESS1824 serum samples collected from employees of four hospitals, 538 from inpatients of one of the hospitals, and 352 from healthy inhabitants (control) of a town near one of the hospitals were surveyed for antibody to adult T-cell leukemia-associated antigen (anti-ATLA). Overall prevalence was 6.3% for the hospital employees, 16.0% for the inpatients, and 12.2% for the control. Office workers (11.5%) and the control subjects (12.2%) had the highest prevalence, and physicians (1.4%) and laboratory technicians (2.4 % ) the lowest. Prevalence was significantly lower in physicians and laboratory technicians than in the control (p<0.05, respectively). Prevalence in nurses (6.3%) was intermediate among the five categories of hospital personnel and lower than in office wokers and the control. These data show that hospital employees may not run a risk of transmitting ATLV through medical care as they do with HBV infections.View full abstractDownload PDF (908K) -
MASAFUMI MARUIWA1987 Volume 34 Issue 3 Pages 133-146
Published: October 01, 1987
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSAn alpha-fetoprotein (AFP)-producing human gallbladder carcinoma with direct invasion to the liver was transplanted into BALB/c-nu/nu nude mice and a new human gallbladder carcinoma cell line (KMG-A) has been established from the transplanted tumor. The patient's serum levels of AFP and carcinoembryonic antigen (CEA) were elevated at 1, 040 ng/ml and 22.1 ng/ml, respectively after the operation. The tumor transplanted into nude mice was a poorly differentiated adenocarcinoma showing both solid and papillo-tubular structures. Serum levels of AFP, CEA, carbohydrate antigen 19-9 (CA 19-9), β2-microglobulin (BMG), and ferritin (FER), were elevated in the nude mice with tumor transplants. The KMG-A cell line has been maintained for 2 years through 80 passages. Morphologic features of KMG-A cells contained varying-shaped and-sized cells, including some multinuclear giant cells. KMG-A cells had one or more large round to oval nuclei with prominent nucleoli. The doubling time of cells grown in a serum-containing medium was about 28.5 hours and KMG-A cells were able to proliferate in a serum-free medium. Functionally, KMG-A cells produced CA 19-9, BMG, and FER, but AFP and CEA were not detectable in the supernatant of KMG-A cells. KMG-A cells were identified as containing AFP, CEA, CA 19-9, and albumin (ALB) by immuno-histochemical techniques. The tumorigenicity of KMG-A cells was not identified by the subcutaneous inoculation of the cells into nude mice 4 months after inoculation, but histological examination of the subcutaneous tissue where the KMG-A cells were inoculated revealed small foci of poorly differentiated adenocarcinoma.View full abstractDownload PDF (13204K) -
NORIKO RIKITAKE, HIROHISA KATO, ON TOYODA, KAZUSHIGE SUZUKI, OSAMU INO ...1987 Volume 34 Issue 3 Pages 147-163
Published: October 01, 1987
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSRecent advances in echocardiography have allowed the anatomical structure of the fetal heart to be successfully and safely seen in details. It has since enabled not only the prenatal diagnosis of congenital heart disease but the diagnosis and treatment of fetal arrhythmias. New advances of Doppler echocardiography have provided exciting informations on the fetal physiology of normal or abnormal fetal circulation. We have performed the fetal echocardiography from 1980 on 564 fetuses which comprised 254 normal and 310 high risk pregnacies. From our experiences we discuss the prenatal diagnosis of congenital heart disease and its method and accuracy, the recognition and intrauterine treatment of fetal arrhythmias, the diagnosis of fetal heart failure, the assessment or research of fetal circulation by Doppler echo-cardiography, and finally the management for the fetus with cardiac problems and the ethical issue in fetal cardiology.View full abstractDownload PDF (18420K)
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