All issues
Volume 37, Issue 4
Displaying 1-13 of 13 articles from this issue
- |<
- <
- 1
- >
- >|
-
ROBERT U. PETRELLA, MITSUNORI IWAMOTO, MITCHEL M. YOKOYAMA1990 Volume 37 Issue 4 Pages 209-228
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSAdvances in the understanding of antibody-antigen interactions and inthe production of monoclonal antibodies have outlined possibilities for the broad application of natural immune phenomena to biologic processes oc-curring beyond the functional realm of the immune response.View full abstractDownload PDF (4646K) -
HIDEFUMI KABUTA, MASATOSHI TANAKA, YASUTAKA NODA, SHIGERU YAMAMOTO, MA ...1990 Volume 37 Issue 4 Pages 229-234
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSNK cell activity in beige mice was compared with that in control BALB/c mice and BALB/c mice treated with HSV-2, sarcoma-180 cells, cimetidine and cyclosporine. The NK cell activity in five week-old beige mice was lower than in three week-old BALB/c mice. The NK cell activity in eight week-old BALB/c mice was four to eleven times the activity in BALB/c mice that were three weeks of age. BALB/e mice, injected with 2 mg cyclosporine or 107 plaque forming units (PFU) of HSV-2, had decreased NK cell activity. BALB/c mice, injected with 2 mg cimetidine, 106 sarcoma-180 cells and 6.0×105 PFU of HSV-2, had high NK cell activities compared with the control mice. Cimetidine further increased the effect of HSV-2 or sarcoma-180 on NK activity. BALB/c mice that received a transfer of less than 107 NK cells developed a high resistance against viral infections, but mice that received more than 107 transferred NK cells had a lower resistance to viral infections than the control mice or mice receiving less than 107 NK cells.View full abstractDownload PDF (613K) -
TATSUYA ISHITAKE1990 Volume 37 Issue 4 Pages 235-245
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSCutaneous microcirculatory responses to vibration stress were observed by microphotoelectric plethysmography in a transparent round window installed in the ears of conscious rabbits. Vertical vibrations at frequencies ranging from 8 to 250 Hz were applied to the abdomen of the rabbits for 5 min. The vibrations produced an increase in heart rate and the index of discomfort, and a decrease in blood flow in the skin microcirculation. The maximum re-sponse was observed at 63 Hz. Rhythmic fluctuations in microcirculation were associated with two components : component A had a small amplitude and high frequency, and component B had a large amplitude and low frequency. Vibration exposure led to a large increase in component B and a smaller increase in component A. During vibration exposure, component A was suppressed by treatment with diltiazem, a calcium channel blocker, and was not affected by bunazosin, an alpha-1 adrenoceptor antagonist. The opposite changes were observed for component B. This indicates that components A and B of the rhythmic fluctuations are regulated by myogenic and neurogenic activities, respectively. Thus, the hemodynamic changes of skin microcirculation induced by vibration may actually be due to a neurogenic factor, especially sympathetic nerve activity. The responses appear to depend on the frequency of the vibrations.View full abstractDownload PDF (4389K) -
KEI MATSUOKA, SHOGO VEDA, KOSAKU ETO1990 Volume 37 Issue 4 Pages 247-251
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSPercutaneous nephroureterolithotripsy was performed a total of 309 times in 225 renal units of 209 patients with upper urinary tract calculi, a mean of 1.37 times per kidney. Residual calculi, 5 mm or greater in diameter, were observed in 3 of 100 kidneys (3%) with single calculi, 12 of 102 kidneys (11.8%) with multiple calculi, and 8 of 23 kidneys (34.8%) with staghorn calculi. The number of sessions, duration of nephrostomy, and the frequency of residual calculi were significantly higher in problem calculi, such as multiple, large and staghorn calculi, than in other calculus types. A combination of percutaneous nephroureterolithotripsy and extracorporeal shock wave lithotripsy was considered to be necessary to improve the efficiency of lithotripsy. Complications included a transient fever, bleeding requiring transfusion and perforation of the renal pelvis in a small number of cases, but these were all mild and could be managed by conservative treatment, alone.View full abstractDownload PDF (612K) -
JUN NAKAMURA, KOUICHIRO MINE, SHIGETO YAMADA1990 Volume 37 Issue 4 Pages 253-259
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSA cannula was chronically implanted in the rat ventriculus, and anticonvulsants were administered through the cannula. The effects of the anticonvulsants applied, intraventricully, were investigated on the decreased electroconvulsive threshold induced by pretreatment with α-methyl-p-tyrosine (α-MT), p-chlorophenylalanine (PCPA) or allylglycine. The TRH analog, DN-1417, valproate (VPA), and Phenobarbital (PB) raised the electroconvulsive threshold which had been lowered by a-MT. The reduced electroconvulsive threshold from PCPA was raised by DN-1417, but not by VPA or PB. The allylglycine induced lowering of the electroconvulsive threshold was raised by VPA and PB, but not by DN-1417. Phenytoin had no anticonvulsant effect on rats pretreated with these drugs. From these results, it was concluded that the anticonvulsant action of DN-1417 could be due to enhancement of dopamine and/or serotonin turnover.View full abstractDownload PDF (834K) -
KATSUHIRO MIZOGUCHI, HITOSHI UTSUNOMIYA, HIROYUKI EMOTO, TOMOMI SHIMIZ1990 Volume 37 Issue 4 Pages 261-263
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSA 57 year-old woman with benign exertional headaches induced by swimming is described. The headaches were bilateral, throbbing and occurred while swimming. She had a history of occasional similar headaches while straining during bowel movements. The neurological examination and computed tomographic (CT) scanning were normal. The electroroencephalogram (EEG) had diffuse alpha activity, and no symptoms or significant changes of the EEG were triggered by the Valsalva maneuver, which causes a transient increase in cranial blood pressure and alters the normal vascular balance. She has stopped swimming and since then has never had a headache. No medications were needed. This case demonstrates that not all headaches are triggered by intracranial lesions. Benign exertional headaches should also be considered in the differential diagosis of this type of headache in the elderly.View full abstractDownload PDF (333K) -
TAKAHO TANAKA, JINRYO TAKEDA, KEN HASHIMOTO, KIKUO KOUFUJI, SHOJIRO YA ...1990 Volume 37 Issue 4 Pages 265-269
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSWe report 9 rare cases (7 males and 2 females) of early gastric cancer of the esophagogastric junction. From 1976 to 1988, 1308 cases of gastric cancer were resected in our Institute. Of these, 479 (36.6%) cases were early gastric cancer. Among all 479 early gastric cancers, 9 (1.9%) were located within 2 cm of the esophagogastric junction on the lesser carvature and/or posterior wall of the cardia. This represents 11.7% (9/77) of the cases of cancer at the esophagogastric junction. This incidence contrasts with the 39.5% of early cancers elsewhere in the stomach. Overall, 36.6% (479/1308) were early gastric cancer. Eight of these 9 patients were resected through the abdominal approach and one by the thoracoabdominal approach. Seven underwent proximal and 2 underwent total gastrectomy. On microscopic examination, one cancer was m-cancer, and 8 were sm-cancer. Lymphnode metastasis was found to be absent in all 9 cases. The prognosis of cancer of the cardia is generally poorer than that for adenocarcinoma in the corpus or distal stomach. However, cancer recurrence 22-91 months postoperatively was zero in these 9 cases of early gastric cancer at the esophagogastric junction.View full abstractDownload PDF (1305K) -
JINRYO TAKEDA, KENJI YASUMOTO, SHOJIRO YANO, TAKAHO TANAKA, KIKUO KOUF ...1990 Volume 37 Issue 4 Pages 271-276
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSFrom 1979 to 1988, a total of 1265 cases of gastric cancer were admitted to our Institute. Of these, 80 cases (6.3%) involved hepatic metastasis. Thirty-eight cases (47.3%) underwent gastrectomy (24 distal, 2 proximal, 11 total and one partial). Of these 38 cases, 7 underwent a combined resection of a simultaneous metastatic hepatic tumor. A total of 19 (67.9%) of the 28 cases in H1, 6 (37.5 %) of the 16 cases in H2, and 13 (36.1%) of the 36 cases in H3 underwent gastrectomy. Hepatic metastasis occurred most frequently (18.2%) in Borrmann type 1, 5 % in type 2, 14.9% in type 3 and 8.7% in type 4. Of all 593 resected advanced cases, there were 283 differentiated type, with a hepatic metastasis rate of 14.5%, and 310 undifferentiated type with 7.1 % rate of hepatic metastasis. In H1 and H2, the prognosis after primary gastric cancer resection was better than for unresected cases. Moreover, there have been reports recently of long-term survival using continuous hepatic arterial infusion of anti-cancer durgs, and of combined resection of the metastatic hepatic tumor after curative gastrectomy. Therefore we should not give up these H1 and H2 patients.View full abstractDownload PDF (1562K) -
YASUMI ARAKI, HIROHARU ISOMOTO, TATSUHISA MORODOMI, KAZUO SHIROUZU, TE ...1990 Volume 37 Issue 4 Pages 277-283
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSThe cellular DNA content was measured with flow cytometry from paraffin-embedded materials in 197 patients with primary rectal cancer who had had “curative” resection. All patients were followed clinically for from 2.5 to 7 years. There was a significant difference in recurrent rate between DNA diploid and aneuploid tumors. The cumulative survival rate (Kaplan-Meier) of curative operative rectal carcinomas was worse in DNA aneuploid than in DNA diploid tumors (p<0.05). These data suggest that tumor DNA content is an important prognostic indicator for both recurrence and overall survival in patients with primary rectal carcinoma.View full abstractDownload PDF (752K) -
Alteration of the Renal Fraction of Blood Flow, Split-GFR, and Renal Mean Transit TimeMASATOSHI ISHIBASHI, SEIICHIRO MORITA, CARLOS A. RABITO, NORIYOSHI UME ...1990 Volume 37 Issue 4 Pages 285-291
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSTo evaluate the therapeutic effects of percutaneous nephroureterolithotomy, the renal function of eleven patients with renal calculi was studied, pre- and post-intervention. Renal function was determined, by renal scintigraphy with the renal agent, Tc-99m diethylenetiaminepentaacetic acid (DTPA). In each renal scintigram the renogram curve was analyzed and the following were determined by deconvolution analysis; the renal fraction of blood flow (RFBF), DTPA-glomerular filtration ratio (GFR), and the renal mean transit time (MTT). The successful results in Percutaneous nephroureterolithotomy (PNL) was proven using the radionuclide technique in most cases. From these results it can be concluded that renal scintigraphy is an effective procedure to evaluate the effect of PNL for treating renal calculi and secondary hydronephrosis.View full abstractDownload PDF (2703K) -
An Electron Microscopic Observations of Two CasesTAMAKA OKINA, KAZUHISA ESAKI, ASAKO NAGATA, JINGO KUSUKAWA, CHIHIRO KO ...1990 Volume 37 Issue 4 Pages 293-299
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSTwo cases of congenital epulis occurring in the gingiva at the site where the lower deciduous incisors were to erupt are described. The first patient was a 7day-old female infant. Her epulis was diagnosed, histopathologically, as a granular cell tumor. Electron microscopy revealed that the tumor cells were large with small eccentric nuclei. The cells were filled with granular structures. These granular substances varied in size and electron density. Case 2 involved a 37 day-old male infant. A histopathological diagnosis of fibromatosis was made. Electron micrographs showed a proliferation of cells which resembled fibroblasts. These cells varied in shape, including some with thin, long processes. Abundant reticular and collagen fibers were present in the stroma. In both cases, the postoperative course was uneventful without recurrence.View full abstractDownload PDF (9824K) -
HIROSHI HASUO, SHINGO SHOJI, TAKASHI AKASU, JOEL P. GALLAGHER1990 Volume 37 Issue 4 Pages 301-307
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSIntracellular recordings were made from neurons of rat dorsolateral septal nucleus (DLSN), in vitro. Adenosine and 2-chloroadenosine (1-500 μM) hyperpolarized DLSN neurons and blocked the excitatory postsynaptic potential (EPSP) and the late hyperpolarizing potential (LHP) in the presence of bicuculline. Adenosine did not depress the glutamate-induced potential. Bath-application of adenosine depressed the baclofen-induced potential in 60% of the neurons. Adenosine also inhibited the LHP in the remaining 40% of neurons, while it did not depress the baclofen-induced potential in these neurons. These results indicate that adenosine inhibits the EPSP pre-synaptically whereas it inhibits the LHP both pre- and postsynaptically in rat septal nuclei.View full abstractDownload PDF (2380K) -
HIROE INOKUCHI, MEGUMU YOSHIMURA, CANTO POLOSA, SYOGORO NISHI1990 Volume 37 Issue 4 Pages 309-312
Published: March 01, 1991
Released on J-STAGE: February 08, 2010
JOURNAL FREE ACCESSDownload PDF (447K)
- |<
- <
- 1
- >
- >|