The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
Volume 54, Issue 3+4
Displaying 1-8 of 8 articles from this issue
Original Contribution
  • YASUMI ARAKI, TOSHIHIRO NOAKE, TAKAAKI NAGAE, YUJI TOU, MOTONORI NAKAG ...
    2007 Volume 54 Issue 3+4 Pages 51-55
    Published: January 31, 2008
    Released on J-STAGE: May 13, 2008
    JOURNAL FREE ACCESS
    The aim of this study is to assess the usefulness of fluoroscopic cystocolpoproctography in the treatment of female pelvic organ prolapse. The presence or absence of rectocele, enterocele, sigmoidocele, and the cystocele on cystocolpoproctography was retrospectively analyzed in 46 consecutive patients. A rectocele was detected in 4.5% of the patients, postvaginal hernia in 19.7%, cystocele in 3.0%, complete rectal prolapse in 53.0%, massive rectal prolapse in 10.6%, and incomplete rectal prolapse in 4.5% of the patients on cystocolpoproctography. Perineal hernia can include a combination of cystocele, rectocele, uterine prolapse, enterocele and rectal prolapse. Accurate diagnosis of the coexisting abnormalities is essential in planning reconstructive procedures so that the risks of recurrence and reoperation can be minimized. Fluoroscopic cystocolpoproctography provides direct visualization and quantification of female pelvic organ prolapse, information that usually can only be inferred by physical examination.
    Download PDF (777K)
  • MOTOTSUGU YAMANO, HIROYUKI OGINO, YUTA SHIBAMOTO, NAOTOSHI HORII
    2007 Volume 54 Issue 3+4 Pages 57-63
    Published: January 31, 2008
    Released on J-STAGE: May 13, 2008
    JOURNAL FREE ACCESS
    Relationship between the grade of radiation pneumonitis (RP) and treatment outcome in lung cancer patients has not been clarified yet. The purpose of this study was to retrospectively evaluate the relationship in patients with primary lung cancer treated by radiotherapy. One hundred thirty-five patients who underwent definitive radiotherapy with known grade of RP were analyzed. RP was scored by using the Radiation Therapy Oncology Group (RTOG) acute radiation morbidity scoring criteria. Survival and local control data were analyzed in relation to the grade of RP. RP was grade 0 in 5 patients, grade 1 in 71, grade 2 in 39, grade 3 in 15 (11%), grade 4 in 0 and grade 5 in 5 (3.7%). There were no significant correlations between patient or tumor characteristics and grade of RP. Excluding 5 patients with grade 5 pneumonitis, survival rates were similar between those with grade 0 or 1 pneumonitis and those with grade 2 or 3. Also, there was no difference in survival between patients with grade 0-2 pneumonitis and those with grade 3. Local control rates were similar between the two groups. Grade of RP did not appear to be associated with prognosis when patients with grade 5 pneumonitis were excluded from analysis.
    Download PDF (631K)
  • SACHIKO NISHIURA, YOUKO NAKASHIMA, KEIICHIRO MORI, TAKAYUKI KODAMA, SA ...
    2007 Volume 54 Issue 3+4 Pages 65-72
    Published: January 31, 2008
    Released on J-STAGE: May 13, 2008
    JOURNAL FREE ACCESS
    To evaluate age and gender differences as well as effects of affection, we examined exploratory eye movements. Exploratory eye movements were recorded in healthy subjects (57 women and 57 men) ranging from 9 to 74 years. All subjects were divided into three groups as pre puberty, young, and older adults to study the influences of age and gonadal hormones. Exploratory eye movements were analyzed for total eye scanning length (TESL), and total numbers of gaze points (TNGP) as subjects viewed neutral or affectively charged pictures. TESL and TNGP in older adults were significantly larger than that in both pre puberty and young adults for crying babies. TESL and TNGP in pre puberty were significantly smaller than that in both young and older adults for circles. TESL and TNGP in pre puberty were significantly smaller than that in older adults for smiling babies. Pre puberty and young adult of both genders for crying babies showed significantly shorter TESL than for when smiling babies. When viewing circles, young adult women had shorter TESL than men. TNGP in young adult women was smaller than in men for circles or crying babies. TNGP of young adult women in the visual right field was significantly smaller than in men. TNGP for crying babies was significantly smaller than that for smiling babies in young adults of both genders for the left field. Exploratory eye movements thus are a useful marker of visual cognitive function. Gender differences were limited to younger adults, suggesting influences of gonadal hormones.
    Download PDF (775K)
  • KANEATSU HONMA, NANCY L. KOLES, HASAN B. ALAM, JAMES C. KEITH Jr., MAT ...
    2008 Volume 54 Issue 3+4 Pages 73-76
    Published: January 31, 2008
    Released on J-STAGE: May 13, 2008
    JOURNAL FREE ACCESS
    The purpose of this study was to determine whether recombinant human interleukin-11 (rhIL-11) could dose-dependently improve the hemodynamic function. Using a swine hemorrhagic shock model, rhIL-11 was given at the beginning of resuscitation. The animals were randomized to receive a single dose of rhIL-11 (5, 20, or 50 μg/kg, group I to III for respectively) or saline (group IV). Blood, urine and both pleural and peritoneal effusion were thus obtained and analyzed. The mean arterial pressure (MAP) was higher post-resuscitation (PR) in group III (62.9±8.2 mmHg) than in groups I, II and IV (54.9±1.7, 53.9±4.3, 55.9±9.4 mmHg, respectively) (P<0.01). The urine output (I: 999±428, II: 1249±180, III: 1434±325, IV: 958±390 ml) and the cardiac output (CO) (I: 3.01±0.66, II: 3.30±0.49, III: 3.43±0.57, IV: 2.73±0.49 L/min.) increased in a dose dependent manner of rhIL-11. CO level and urine output were significantly higher in group III than in group IV (P<0.05). In addition, the volume of third space fluid loss (pleural and peritoneal effusion) of group III was significantly lower than other groups (I: 157±32, II: 138±32, III: 82±21, IV: 125±32 ml) (P<0.05). In conclusion, even a low dose of rhIL-11 improved the hemodynamic functions dose-dependently in a porcine model of hemorrhagic shock, although the relationship did not demonstrate a simple linearity.
    Download PDF (572K)
  • YOSHINORI YOKOKURA, NOBUHIKO HAYASHIDA, TEIJI OKAZAKI, EIJI NAKAMURA, ...
    2008 Volume 54 Issue 3+4 Pages 77-84
    Published: January 31, 2008
    Released on J-STAGE: May 13, 2008
    JOURNAL FREE ACCESS
    Bone marrow implantation (BMI) enhances angiogenesis in several animal models of ischemic diseases, and it is currently applied in the clinical treatment of humans. However, the mechanisms of this effect have not yet been fully described. Rat bone marrow mononuclear cells (BM-MNCs) were obtained by Histopaque density gradient centrifugation and injected directly into the ischemic myocardium of the test rats (BMI group), which were then examined and compared with the groups that received surgery only (Controls) or surgery and an injection of phosphate buffered saline (PBS group). Cardiac function was evaluated by echocardiography, and neovascularization was examined both histologically and immunohistochemically before, 1 day after, and 7 or 28 days after the operation. BM-MNCs were analyzed by fluorescence staining for the endothelial cell marker CD31 and alkaline phosphatase (ALP). The mechanisms of angiogenesis were examined by gene expression analysis. In the BMI group, cardiac function parameters at 7 days after operation were significantly improved and the number of capillaries in the myocardium was significantly larger than that in the PBS and Control groups. Gene analysis showed the expression of 12 genes in the BMI group 7 days after operation. The implantation of BM-MNCs into the myocardiumin cases of acute infarction enhances cytoprotection and angiogenesis by affecting gene expression.
    Download PDF (943K)
Case Report
  • KANEATSU HONMA, YASUHISA TANGO, KENICHI HONMA, HIROHARU ISOMOTO
    2008 Volume 54 Issue 3+4 Pages 85-88
    Published: January 31, 2008
    Released on J-STAGE: May 13, 2008
    JOURNAL FREE ACCESS
    This report describes a case of rectal cancer with severe interstitial pneumonia (IP) and chronic pneumothorax. Acute exacerbation of IP is a serious postoperative complication and the consequences are extremely poor. To provide less invasive surgery and to prevent acute exacerbation of the IP, the patient received chemo-radiotherapy for controlling locally advanced tumor following low anterior resection under combined spinal-epidural anesthesia. Adequate epidural analgesia during the postoperative period had been shown and the epidural catheter was removed on the 3rd postoperative day. The patient showed symptoms of intrapelvic abscess due to the anastomotic leakage at 10th postoperative day. In order to avoid complications due to spinal and epidural anesthesia (epidural abscess, meningitis), and to prevent acute exacerbation of the IP, general anesthesia was employed with minimal fraction of inspired oxygen (FIO2) to perform the colostomy for the anastomotic leakage. The patient recovered without any postoperative respiratory complications. We herein report the successful perioperative management of a rectal cancer patient with severe IP and chronic pneumothorax, with special attention paid to the respiratory functions.
    Download PDF (663K)
  • AKIRA YAKEISHI, TSUYOSHI SAGA, HIROKO SO, MAKOTO TETSUKA, YOSHIO ARAKI ...
    2008 Volume 54 Issue 3+4 Pages 89-93
    Published: January 31, 2008
    Released on J-STAGE: May 13, 2008
    JOURNAL FREE ACCESS
    During a gross anatomy course at Kurume University School of Medicine in 2001, an anomaly of the kidneys was found. The lower ends of the kidneys were fused by a renal substance and formed a horseshoe kidney located ventral to the abdominal aorta and inferior vena cava. Both renal hila opened very widely in the ventral direction, with the left hilum being larger than the right. This horseshoe kidney had original left and right renal arteries that branched from the abdominal aorta. As well, there were four surplus renal arteries. The first surplus artery branched from the right renal artery and was distributed to the upper pole of the right kidney. The second arose from the abdominal aorta and was distributed to the inferior pole of the right kidney. The third arose from the abdominal aorta and was distributed to the inferior pole of the left kidney and part of the isthmus. The fourth branched from the abdominal aorta and was distributed to the upper pole of the left kidney. The incidence of horseshoe kidneys in Japanese anatomical dissections has been reported as 0.15-0.48%. This was the sixth such case for our laboratory, representing a frequency of 0.1% (6 of 1902 dissections) from 1952 to 2001.
    Download PDF (770K)
  • TAKASHI OHYA, SHINICHIRO NAGAMITSU, YUSHIRO YAMASHITA, TOYOJIRO MATSUI ...
    2008 Volume 54 Issue 3+4 Pages 95-99
    Published: January 31, 2008
    Released on J-STAGE: May 13, 2008
    JOURNAL FREE ACCESS
    We report a 5-year-old mentally retarded Japanese boy who developed acute disseminated encephalomyelitis (ADEM) two weeks after Japanese encephalitis vaccination (Beijing strain). He presented sudden status epilepticus, fever, and disturbance of consciousness. Initial neuroradiological findings revealed multifocal cortical swellings without any white matter lesions, suggesting the existence of partial encephalitis or focal status epilepticus. On the follow-up neuroradiological examinations, small white matter lesions were identified as having gradually extended in spite of clinical improvement by methylprednisolone pulse therapy. The cortical involvement became temporarily worse along with the extension and delayed appearance of white matter lesions. Single photon emission computed tomography (SPECT) showed marked hypoperfusion of cerebral blood flow (CBF) in the cortical lesions at both the acute and the recovery period. The serial neuroradiological findings indicated involvement of white matter and gray matter regions at different stages of the illness and a delay between the onset of symptoms and the appearance of ADEM-associated MR imaging of white-matter lesions.
    Download PDF (774K)
feedback
Top