The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
Volume 31, Issue 1
Displaying 1-6 of 6 articles from this issue
  • A Comparison of High-Dose Cyclophosphamide, vincristine and Adriamycin Therapy with James' Therapy plus Adriamycin
    YASUHIKO HIYOSHI, HIROMICHI YANO, TETSURO TANAKA, AKIHIKO NOGUCHI, TAM ...
    1984 Volume 31 Issue 1 Pages 1-6
    Published: September 10, 1984
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    Sixteen children with Stage III and N neuroblastoma were treated using two different chemotherapy protocols; six with a James' therapy plus adriamycin, and ten with a regimen consisting of high-dose cyclophosphamide, vincristine and adriamycin in a nonrandomized fashion. The highdose cyclophosphamide with vincristine and adriamycin appeared to improve the duration of survival; that is, in the patients treated by this protocol, the median survival duration was 25 months, the one-year survival rate was 75% and the three-year survival rate was 50%. On the other hand, none of the patients treated by James' therapy plus adriamycin survived for more than one year. Their median survival was only four months.
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  • YOUICHIRO ICHIKAWA, SHUNJI HAYASH, MASARG KAJI
    1984 Volume 31 Issue 1 Pages 7-13
    Published: September 10, 1984
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    Ga-67 scanning was used to evaluate 32 patients with sarcoidosis, 20 patients who were untreated and 12 who were treated. The level of serum angiotensin converting enzyme (ACE) was measured in all patients and bronchoalveolar lavage was performed in 10 untreated patients and 7 treated patients. Ga-67 scanning was compared with the level of serum ACE and the number of lymphocytes, espeically T-lymphocytes in the bronchoalveolar lavage fluid. Ga-67 scanning was useful for the detection and assessment of subclinical lesions that were not identified with traditional methods of investigation. Although the extent of Ga-67 accumulation in the lungs of patients with untreated sarcoidosis did not correlate with the serum ACE level, it did correlate with the number of lymphocytes, especially T-lymphocytes, in the bronchoa-Iveolar lavage. Based on this finding, the Ga-67 scanning method should be useful for evaluating the locus and the activity of T-cell alveolitis, an early sign of sarcoidosis. This method should provide useful clinical indices for the determination of the stage of sarcoidosis, for the evaluation of therapeutic procedures, and for the assessment of prognosis.
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  • NORIYOSHI UMEZAKI, KOUICHI TOYOSHIMA, KIMIYOSHI TAKADA, TOSHINORI KOGA ...
    1984 Volume 31 Issue 1 Pages 15-20
    Published: September 10, 1984
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    The use of gadolinium (Gd) as a “band pass” filter for the X-ray contrast examination is discussed. Vinyl tubes filled with iodine solution were placed in a water phantom (15 cm thickness). When this phantom was exposed to a 70 kVp X-ray filtered by a Gd-filter, to give an equal film density as an aluminium (Al) filter, the surface dose was reduced by 45 % . The effective attenuation coefficient of the iodine for an 80 kVp X-ray filtered with a Gdfilter of 0.4 mm thickness corresponds to that for a 70 kVp X-ray filtered with an Al-filter of 2 mm thickness. These results indicate that a decrease of skin dosage and an increase of film contrast are obtained by using a Gd-filter for the X-ray examination with an iodine contrast medium.
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  • TAKASHI HAYASHI, KAZUHITO SHYOJIMA, EIICHIRO HONDA, TAKAO SHYOJIMA, SH ...
    1984 Volume 31 Issue 1 Pages 21-25
    Published: September 10, 1984
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    Since the report by Lundberg (1960), the importance of analysis of pressure waves has been recognized with respect to the intracranial pressure, apart from the level of pressure. More recently, various instruments for measuring the intracranial pressure have been developed and measurements of the extradural and intraventricular pressure have become relatively easy. At the same time, efforts to analyse pressure waves are equally intensive. Since the skull of a newborn or infant is not closed and the intracranial environment is considerably different from those of an adult skull, the pressure waves themselves, rarely behave as classified by Lundberg (1960). Recently during the treatment of hydrocephalus due to intraventricular hemorrhage, in a premature infant, there was a complication causing the so-called isolated fourth ventricle, after ventriculoperitoneal shunt. When the intracranial pressure was measured in this case using our “Fontanometer” (NEC, Sanei Co.), B-waves, so named by Lundberg (1960), were clearly observed. From the results in this case, the mechanism of occurrence of the B-wave will be discussed based on our experience and previously published reports.
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  • TAKASHI HAYASHI, TETSURO KADOWAKI, TAKEO HASHIMOTO, KAZUHITO SHOJIMA, ...
    1984 Volume 31 Issue 1 Pages 27-35
    Published: September 10, 1984
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    We have experienced 15 cases of cranium bif idum in the past 3 years, including 4 cases with frontal cranum bifidum. The sites were frontoethmoidal in 2 cases and interfrontal in 2 cases. They have been followed from 1 to 3 years of age and all are living. As complications, 1 case had intracranial lipoma and 2 cases had myelomeningocele. Restoration of frontal encephalomeningocele and honey defect was performed by an intracranial procedure in 2 cases. Severe hypertelorism in 1 case was corrected by bilateral transfer of the whole orbit at one year after birth. There are few reports of frontal cranium bif idum in Japan. Three cases with craniolacunia were all complicated by congenital hydrocephalus and ventriculoperitoneal shunt was carried out. The above 4 cases were analysed clinically and are here reported.
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  • FUMITAKA TAYAMA, TAKESUKE MUTEKI, SHIGEAKI BEKKI, TOKUZIRO YAMASHITA, ...
    1984 Volume 31 Issue 1 Pages 37-46
    Published: September 10, 1984
    Released on J-STAGE: August 11, 2009
    JOURNAL FREE ACCESS
    We have studied changes in both cardiac performance and the peripheral circulation in order to investigate cardiovascular influences due to electro-acupuncture stimulation (EAP) at the two meridian acupoints (Penicardium and Large Intestine) related to cardiovascular activities. 1) No significant changes were seen in blood pressure and heart rate after EAP at P 4-6. However, the impedance SV and CO wete increased markedly with the same condition of EAP. 2) As for stroke volume and cardiac output, EAP had greater effects than dopamine 4 μg/kg/min and dobutamine 8 μg/kg/min and had almost the same effect as Haemaccel 2 ml /kg (0.25 μg/kg/mm). 3) No significant changes were seen in blood gas tensions or electrolytes but plasma colloidal osmotic pressure tended to decrease. 4) After EAP at LI 4-10, radial artery was dilated; and the constrictive response of radial artery under the influence of autonomic nerves remained as normal. 5) Changes in cardiac performance, peripheral blood circulation and somatosensory evoked potentials (SEP) were maximal about 10 minutes after EAP was applied. 6) Concerning EAP effects on cardiac performance and peripheral blood circulation and SEP, EAP at P4-6 and LI 4-10 induced significant changes but EAP at non-acupoint had no significant effects.
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