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Volume 23, Issue 1
Displaying 1-6 of 6 articles from this issue
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TAKASHI AKASU1976 Volume 23 Issue 1 Pages 1-11
Published: May 25, 1976
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSEffects of ATP on the potassium-activated hyperpolarization of bullfrog sympathetic ganglion cells, postganglionic and splanchnic nerve-axons were studied. The potassium-activated hyperpolarization recorded from ganglion-postganglionic nerve preparations by the sucrose-gap method was augmented in the presence of ATP in concentrations between 0.05-1 mM. The potassium-activated hyperpolarization of postganglionic and splanchnic nerve-axons was also augmented by ATP in the same experimental conditions. The facilitating effect of ATP on the potassium-activated hyperpolarization was depended on its concentration and was entirely reversible. The potassium-activated hyperpolarization recorded from ganglion cell-bodies by intracellular microelectrodes was similarly augmented by ATP (0.05 mM). ATP in this concentration caused no significant changes of the membrane potential and conductance in the presence of ouabain (0.002 mM), which completely and reversibly inhibited the potassium-activated hyperpolarization. ADP and AMP showed similar but less effects and adenosine showed no significant effect on the potassium-activated hyperpolarization. These results suggested that ATP applied to the extracellular fluid could be utilized without being decomposed to ADP, AMP or adenosine, and it augmented the sodium pump either by acting to cell surfaces or by being absorbed into cells.View full abstractDownload PDF (2326K) -
A CASE REPORTAKIRA TANIMURA, TATSUO YAMAGUCHI, HIDENORI SHIBATA, TSUYOSHI ARITA, TS ...1976 Volume 23 Issue 1 Pages 13-17
Published: May 25, 1976
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSA case of 12 years old girl with duodenal carcinoid tumor is presented. Grossly tumor originated from II part of duodenum and its two-third was covered by pancreas parenchyma but no invasive into pancreas tissue. Tumor tissue consisted of uniform cell pattern with clear cytoplasm and small round nuclei but not atypical. Tumor cells were arranged into rosette and pseudorosette formation, especially predominant pseudorosettes.View full abstractDownload PDF (4225K) -
MAKOTO YOSHINO, YASUYUKI ESAKI, SACHIHIKO SHIBUYA, MASASHI YAMAMOTO, C ...1976 Volume 23 Issue 1 Pages 19-28
Published: May 25, 1976
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThree patients with acute encephalopathy and evidences of liver damage are presented. One of them was diagnosed as having Reye syndrome on the basis of light microscopic and electron microscopic observations on liver histology as well as clinical and laboratory evidences. Other 2 patients had liver histology different from that seen in Reye syndrome, despite they had clinical features and laboratory findings which were very similar to those of Reye syndrome. We propose from these experiences that diagnosis of Reye syndrome can only be made with histological evidence. Studies on the pathophysiology of other 2 patients who showed very similar metabolic alterations may given an alternative way to reach the essential pathogenesis of Reye syndrome, which may provide us with the possibility of nonhistologic diagnosis of Reye syndrome.View full abstractDownload PDF (8536K) -
ZENSAKU YOSHII, MASAHIRO NAKAMURA1976 Volume 23 Issue 1 Pages 29-39
Published: May 25, 1976
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSPartial swellings of cell bodies of Mycobacterium lepraemurium cultivated in the NC-5 medium were observed with a scanning electron microscope. Shapes, sizes, locations, dividing and budding forms of the partial swellings were described. The partial swelling was regarded as the growing phase of a stage in the life history or life cycle of Mycobacterium lepraemurium. Similarity of the swelling to a bacterial spore was also noticed, however, further investigation is required for the determination of its microbial significance.View full abstractDownload PDF (13079K) -
MITSUO YOKOYAMA, JUDITH HSIA, MASAYUKI NISHIKI, C. W. Q. LEE, S. J. TA ...1976 Volume 23 Issue 1 Pages 41-47
Published: May 25, 1976
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSVarious species of starfish were collected and extracts were prepared from them to study the agglutinating properties of human red cells. The present results reveal that there are agglutinating substance in all extracts in particular, Pentaceros hawaiiensis and Linckia multifora showed agglutinins more predominant in reacting with group A and B red cells respectively. However, absorption experiments with immunodominant sugars, red cells and saliva showed that the agglutinating substances were not specific in the ABO blood roup.View full abstractDownload PDF (829K) -
I. IDENTIFICATION OF 2-CARBOXY-5, 6-DIHYDROXYINDOLETOSHIHIRO HIDAKA1976 Volume 23 Issue 1 Pages 49-56
Published: May 25, 1976
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe metabolic pathway of tyrosine to melanin catalyzed by mushroom-tyrosinase was investigated. A compound was isolated from tyrosine-tyrosinase reaction mixture by means of organic solvent extractions, thinlayer and gas chromatographies. The isolated compound was identified as 2-carboxy-5, 6-dihydroxyindole by GC-mass spectrometry. It may be fairly asserted that this compound is derived from 2-carboxy-2, 3-dihydroindole-5, 6-quinone.View full abstractDownload PDF (4717K)
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