巻号一覧
21 巻 (1971)
- 4 号 p. 155-
- 3 号 p. 81-
- 2 号 p. 41-
- 1 号 p. 1-
前身誌
21 巻, 1 号
選択された号の論文の4件中1～4を表示しています
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I. 日脳アジュバントワクチンによるブタのウイルス血症予防安藤 泰正1971 年 21 巻 1 号 p. 1-5
発行日: 1971/04/01
公開日: 2010/03/16
ジャーナル フリーPrevention of viremia of Japanese encephalitis virus (JEV) in naturally infected swine is one of the most important and necessary measures for the prophylaxis of human JEV infection in Japan, and effective vaccination procedures for animals are expected.
Twenty healthy swine, between 50-80 days of its age, borne in Tokyo were selected and immunized against JEV, by injecting 5ml of Toshiba's purified JEV inactivated vaccine which suspended with equal volume of Dorakeol-6.
Eight weeks after the last immunization, intradarmal virus challenge was made by inoculating 2 or 4ml of 10% emulsion of JaGAr 01 strain infected mice brain (106.5-7.2 LD50 in mice). Detection of viremia was made by the intracerebral inoculation of the blood samples of the immunized swine into a litter of suckling mice.
The results obtained are summarized as follows:
1) Equivocal effectiveness of our adjuvant vaccine was observed when animals were immunized by the single injection method, however, the animals responded to the vaccination by the production of JE HI antibodies greater than 1:10 in their titer were consequently free from viremia when they were challenged by the wild type of JE virus.
2) Duplicated vaccination made on the animals at 7 weeks after the first ones, induced considerable amounts of long, lasting JE HI antibodies, and all the animals did not manifest viremia when they were challenged.抄録全体を表示PDF形式でダウンロード (658K) -
坂岡 博, 松井 克彦, 山田 守英1971 年 21 巻 1 号 p. 6-11
発行日: 1971/04/01
公開日: 2010/03/16
ジャーナル フリーSynthesis of interferon (IF) was induced in chick embryo fibroblast (CE) cells by inoculations of Sindbis virus (SDV), and Newcastle disease virus (NDV) on SDV after irradiation of UV (UV-NDV or UV-SDV). However, CE cells infected with live NDV failed to produce IF. The IF production by these agents was found to be strongly inhibited by the superinfection of some live viruses. Following results were obtained.
1. The IF production in CE cells primed with SDV, UV-NDV and UV-SDV was suppressed by 1/8-1/64 fold by superinfection of NDV. Suppression of IF production was also observed in CE cells infected with doubly SDV and UV-NDV.
2. These inhibition were also observed in CE cells infected with UV-NDV or SDV by the superinfection with polio-virus and HVJ, but were not observed when influenza type A virus was employed as superinfecting virus.
3. The higher m. o. i. of superinfecting virus, the stronger the inhibition of the IF productions. However, the inhibition was not observed in CE cells inoculated doubly with UV-NDV, UV-SDV.
4. When superinfecting virus, NDV was introduced within 2 hours after inoculation of UV-NDV, IF synthesis was completely inhibited, however, the addition of NDV at 5 hours after the inoculation of UV-NDV was without effect.
5. The adsorption of UV-NDV to CE cells was not inhibited by the preinfection of SDV, and the synthesis of SDV was enhanced by the addition of UV-NDV to CE cells.抄録全体を表示PDF形式でダウンロード (918K) -
森田 睦郎, 長谷川 久則, 工藤 重則, 市原 俊二1971 年 21 巻 1 号 p. 12-14
発行日: 1971/04/01
公開日: 2010/03/16
ジャーナル フリーIsolation of Japanese encephalitis virus was attempted from Culex tritaeniorhyncus and the blood from slaughtered swines during the summer from 1967 to 1970 in Oita Prefecture. Virus was isolated 7 days in 1967, 3 days in 1968, 13 days in 1970 earlier from the swines than from the pools of collected Culex tritaeniorhynchus.
Only in 1969, the virus was isolated from the mosquitoes 7 days earlier than from the swines.
Isolation of the virus from slaughtered swines may provide an adequate tool in the local laboratories for a certain purpose of the epidemiological study of Japanese encephalitis comparing with the laborious works of virus isolation from mosquitoes collected in the field.抄録全体を表示PDF形式でダウンロード (426K) -
藤村 有信1971 年 21 巻 1 号 p. 15-16
発行日: 1971/04/01
公開日: 2010/03/16
ジャーナル フリーPDF形式でダウンロード (231K)
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