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Volume 36, Issue 1
Displaying 1-7 of 7 articles from this issue
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KATSUHIRO FUKUDA, MASAMICHI KOJIRO, MINORU HIRANO, VINCENT J. HYAMS, D ...1989 Volume 36 Issue 1 Pages 1-6
Published: June 01, 1989
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe reasons for the prevailing predominance of maxillary sinus squamous cell carcinoma and the rarity of maxillary sinus adenocarcinoma among Japanese were investigated in a cooperative study at two institutions. There was little difference in the histological diagnostic criteria. It is hypothesized that the predominance of squamous cell carcinoma and the rarity of adenocarcinoma of the maxillary sinus can be related to the extensive use of softwood in the Japanese furniture industry, to the high prevalenc of chronic sinusitis among Japanese in the past or to the popularity of cigarette smoking among Japanese.View full abstractDownload PDF (726K) -
SHIGERU YAMAMOTO, HIDEFUMI KABUTA, MASAHISA SHINGU1989 Volume 36 Issue 1 Pages 7-16
Published: June 01, 1989
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSMutants derived from herpes simplex vitus type 1 (HSV -1) strains, YH and KOS, that were defective in cell fusion function (r mutants) were examined for DNA structure using a restriction endonuclease and gel electrophoresis. A distinct difference in the restriction patterns was found in some r mutants. One which was derived from strain YH and belonged to complementation group A lost the BamHI cleavage site in the long inverted repeat regions. But the site could not be associated with the gene that was related to the cell fusion event, inasmuch as the other mutants belonging to the same complementation group had a normal BamHI site. The others, which belonged to complementation group G of strain KOS, had a deletion of approximately 2 kb (kilobase-pair) in the BamHI B fragment. A mixed infection was carried out with r410 and r426 which belonged to groups A and G of strain KOS, respectively, and the viruses of parental and recombinant types were isolated from the progeny. The BamHI restriction fragment patterns of the DNAs showed that all recombinants, which carried the cell fusion ability, had the normal BamHI fragment B. Thus, one of the genes associated with cell fusion function must be located in BamHI fragment B.View full abstractDownload PDF (10685K) -
MASAMI YOSHIDA, MASATOSHI TANAKA1989 Volume 36 Issue 1 Pages 17-21
Published: June 01, 1989
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSGABA-and glycine-containing neuronal elements were visualized in the rat spinal cord by immunohistochemistry employing antisera raised against conjugated GABA and glycine. GABA-and glycine-like immunoreactivities were localized in axon terminals and neuronal perikarya. GABA-and glycine-like immunoreactive terminals were in synaptic contact with perikarya and dendrites of most spinal neurons. Single spinal motoneurons appeared to be in contact with GABA-or glycine-like immunoreactive terminals. These findings suggest that these neurons are regulated postsynaptically by both GABA and glycine.View full abstractDownload PDF (4127K) -
YOSHIHIRO SATO, YOUSUKE SATO, SHINICHI KAKISAKO, YOSHIAKI HONDA, MASAR ...1989 Volume 36 Issue 1 Pages 23-27
Published: June 01, 1989
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThree different cases of cerebral embolism occurring in combination with hyperthyroidism are reported. Case 1; a healthy 37-year-old woman presented with sudden onset of left hemiparesis and left sided hypoesthesia of all modalities. Embolism in area of the right middle cerebral artery was confirmed by angiography and CT scan. Laboratory examination revealed hyperthyroidism and anemia. Antithyroid treatment brought about euthyroid function while slight hemiparesis remained present. Case 2; a 79-year-old woman who suffered from hypertension for one year had sudden onset of disorientation and left hemiparesis. Electrocardiogram showed atrial fibrillation. The CT scan indicated infarction in the right anterior and middle cerebral artery. The patient was diagnosed as having masked hyperthyroidism. Although antithyroid medication reduced it to euthyroid condition, the patient is now bedridden with hemiparesis. Case 3; a 45-year-old man who had partial thyroidectomy for Basedow's disease and had been treated with antithyroid and antiarrhythmic therapy for 10 years. Suddenly, he was in coma with dilated right pupil and left hemiplegia. Atrial fibrillation and hypothyroid function were observed. CT scan indicated hemorrhagic infarction in the territory of the middle cerebral artery with transtentorial herniation. He died on the 59th day of hospitalization following an episode of bronchopneumonia. On the basis of the cases presented here as well as on the basis of those described in the literature it appears that thyrotoxic patients with atrial fibrillation exhibit high incidence of cerebral embolism, and prophylactic anticoagualnt therapy may be recommended.View full abstractDownload PDF (6035K) -
YUICHI YAMASHITA, HIROHARU ISOMOTO, TERUO KAKEGAWA1989 Volume 36 Issue 1 Pages 29-33
Published: June 01, 1989
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSGastrin release of porcine gastrin releasing peptide (pGRP) and its related peptides were evaluated. The concentration of serum gastrin after intravenous administration of the peptides was measured by a radio immunoassay. Among pGRP and its related peptides, pGRP was found to retain full bombesin potency with respect gastrin release. The carboxy-terminal fragments of pGRP, 14-27, 18-27, and 19-27 were equipotent for gastrin release, though the peak value of serum gastrin caused by each of these three fragments was significantly less than that evoked by pGRP. The pGRP fragment 20-27, despite showing considerably lesser potency, still evoked statistically significant levels of serum gastrin during its infusion. On the other hand, pGRP fragments 21-27 and 1-13 did not exhibit any appreciable activity. It was concluded that the carboxy-terminal octapeptide 20-27 constitutes the vital active core for gastrin releasing activity of the pGRP molecule. The amino-terminal tridecapeptide pGRP (1-13), while itself inactive, appeared to be important for the full active of pGRP.View full abstractDownload PDF (1588K) -
JINRYO TAKEDA, YUH HIRAI, HIROSHI FUJIMASA, KEN HASHIMOTO, TERUO KAKEG ...1989 Volume 36 Issue 1 Pages 35-39
Published: June 01, 1989
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSTo improve surgical results of duodenal ulcer, transgastric myotomy (TGM) was added to the traditional selective proximal vagotomy (SPY) and its efficacy was evaluated clinically in 40 patients. 35 men and 5 women were involved, with a mean age of 33.07±14.25 years. Pyloroplasty was added in 12 operations for stenosis and perforation. 28 patients in this series underwent TGM with SPV without drainage. In the 36 patients, basal and maximal acid output (BAO and MAO) was compared preoperatively and at 6 months postoperatively. A satisfactory reduction of acid output was achieved, with a mean reduction rate of 71.4% in BAO ; and of 79.9% in MAO. All 40 patients were negative in Hollander's insulin stiriulation test at 6 months postoperatively. The gastric mucosa was injured during myotomy in 2 of the patients (5.0%), and was simply sutured using 3-0 Dexon, without causing any problems. No other early or late postoperative complication was present. In addition, no peptic ulcer recurrence has been noted over a maximal follow-up of 8 years. The present results suggest the completeness of gastric denervation by TGM+SPV, and establish the efficacy of TGM with SPY, and therefore this method is recommended in the surgical treatment of duodenal ulcer.View full abstractDownload PDF (1752K) -
ZENO POPOVICI1989 Volume 36 Issue 1 Pages 41-47
Published: June 01, 1989
Released on J-STAGE: August 11, 2009
JOURNAL FREE ACCESSThe author presents a series of 235 esophagocoloplasties, in 90 cases a pharyngeal reconstruction being performed. The colic graft was anastomosed to the hypopharynx in 43 cases, to the oropharynx in 14 cases, and in 33 cases a pharyngoplasty was done. A personal classification of the approach of the pharynx according to local innervation is attempted, and various original procedures of pharyngeal reconstruction are described (double pharyngoplasty “en Y”, pharyngoplastia “vera”). A great effort was made in preservation of the larynx, which remains the main aim of the author.View full abstractDownload PDF (5443K)
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