日本化粧品技術者会誌
Online ISSN : 1884-4146
Print ISSN : 0387-5253
ISSN-L : 0387-5253
28 巻, 2 号
選択された号の論文の7件中1~7を表示しています
  • 塩貝 芳樹
    1994 年 28 巻 2 号 p. 129-138
    発行日: 1994/09/15
    公開日: 2010/08/06
    ジャーナル フリー
    We are visted by a serious depression, then a consumer's spirit and his action style are varied. In such social conditions, we, cosmetic chemists are needed to develop the goods selling well that he want to buy, when he want.
    In the other hand, a individual difference is exist in our developing process and process time, and it was inefficient. Therefore, we have to improve our developing process from now.
    Then we found the new method to do so within the Q. C. methods. It is Quality Functional Deployment. In this paper, we show the example to develop a long-lasting two-way foundation.
  • 中村 高志, 北條 聡子, 左近 健一
    1994 年 28 巻 2 号 p. 139-146
    発行日: 1994/09/15
    公開日: 2010/08/06
    ジャーナル フリー
    The texture, physical properties, and stability of solid cosmetics are largely influenced by the crystalline structure of waxes that are incorporated. It has also been known that the selection of raw materials affects the hardness and solidifying points of these wax-oil mixtures. Therefore, to understand the crystallizing mechanism of wax-oil mixtures, DSC measurements and X-ray diffraction were performed.
    The observations were as follows:
    1: X-ray diffraction pattern of the oil phase showed specifically for non-crystalline structures. Furthermore, waxes were observed to form crystals separately in mixtures.
    2: The addition of oil changed the crystalline structure of waxes to microstructures, then in turn lowered the solidifying temperature of the mixture.
    3: When an organic powder was mixed in the mixture of carnauba wax and squalane, it was found that its solidifying temperature increased and its degree of hardness decreased. However, there was little change in the solidifying temperature and the degree of hardness when an inorganic powder was mixed in this mixture. It was discovered that thermodynamic behavior of the mixtures differed with a kind of organic pigments. On the contrary, DSC patterns were similar between the same surface treatment on organic pigments.
    These results suggested that characteristic of powder surface has an influence on the solidifying temperature.
  • 舛田 勇二, 武井 希世子, 水垣 めぐみ
    1994 年 28 巻 2 号 p. 147-152
    発行日: 1994/09/15
    公開日: 2010/08/06
    ジャーナル フリー
    In order to develop more effective whitening cosmetics, it is necessary to measure the efficacy of the whitening agent objectively. A new quantitative measurement method of stains on the face is called for. We therefore have developed a system in which we measure stains on both an arbitrary part of the face and an arbitarary measure area of that part. We then express the measured values using ITV camera. In this way, we analyze typical brown spots and freckles.
    In this system-which we call REMO-STAIN System (Remote stain measurement system)-the face image without stains is processed from original face image using pixel averaging procedure. The Lab value is calculated from the difference between original image and processed image for each pixel. The color defference (dE) is calculated from Lab maps and expressed in mapping expression. We propose that average of dE obtained from REMO-STAIN System be used as the new index of brown spots and freckles.
    We analyzed the measurements of typical brown spots and freckles, including senile lentigos (age spots), melasma (liver spots) and ephelides (freckles).
  • 川口 由起子, 金子 治, 小松原 良平, 吉澤 徹
    1994 年 28 巻 2 号 p. 153-162
    発行日: 1994/09/15
    公開日: 2010/08/06
    ジャーナル フリー
    The skin surface is characterized by small ridges, prominences and furrows that change with aging and degree of sun expose. Quantifying such geometric characteristics as the ridges and furrows on the skin surface can provide cosmetic researchers with a means of assessing changes in wrinkles and understanding the wrinkling process.
    Many attempts have been tried to analyze the features of wrinkles in order to evaluate the efficacy of anti-wrinkles preparations. However, measurement systems proposed up to now have been unable to provide 3-D information about wrinkle shapes. The authors have developed a new non-contact 3-D measurement system to profile wrinkles based on a fringe scanning method using a sinusoidal grating pattern instead of interference fringes generated by laser. The grating projection system makes it possible to capture the three-dimensional nature of the objective. Another feature of the new device is that fringe scanning is introduced to the grating projection system. The system provides a greater density of measurement points and eliminates the influence of skin surface anomalies such as spots, freckles, moles, etc. Using this system, the depth of wrinkles can be obtained within 1.0 second with a depth accuracy of less than ±14μm over an area of 12.5mm×15mm.
    3-D measurements of wrinkles were taken on the external corners of the eyes of 599 Japanese women ranging in age from 20 to 67. A mathematical model is proposed which aims to assist in understanding the effects of aging and the efficacy of cosmetic products.
  • 笠 明美, 荒金 久美, 増永 卓司, 新本 浩一, 長野 哲雄, 廣部 雅昭, 益子 信郎
    1994 年 28 巻 2 号 p. 163-171
    発行日: 1994/09/15
    公開日: 2010/08/06
    ジャーナル フリー
    Recently the skin damage induced by UV-irradiation has become an interest for the cosmetic industry. Especially in view of photo-induced aging, the importance of UV-A has been emphasized since UV-A penetrates deeply in dermis and is suspected to induce irreversible damage to essential tissue components such as collagen and hyaluronic acid. We examined the skin damage by photodynamic process mainly involving singlet oxygen. Singlet oxygen, which is one of the most reactive of active oxygen species, may induce some damage to biological function of skin. Life-time of singlet oxygen is very short and there has been no method of detecting it evidently. In this work we developed the system of specific detection of singlet oxygen based on emission at 1268nm. Using this system we could directly detect singlet oxygen produced by hematoporphyin-photosensitized reaction. We found that when collagen was exposed to singlet oxygen, α or β chain decreased rapidly and they were converted into γ chain. This reaction was not affected by superoxide dismutase or mannitol. These results indicated that singlet oxygen induced the formation of cross-linked collagen. We suggested that the cross-linking was dependent on histidine residues photo-oxidized by singlet oxygen. Generaly, cross-linking of collagen has been considered to be related to aging but the mechanism of cross-linking has not been investigated intensively. From the result presented here, we speculate that the cross-linked collagen induced by singlet oxygen is related to the photodynamic skin aging.
  • 田中 浩, 岡田 富雄
    1994 年 28 巻 2 号 p. 172-177
    発行日: 1994/09/15
    公開日: 2010/08/06
    ジャーナル フリー
    The excessive loss of collagen is well known in photoaging skin. Collagen is synthesized by dermal fibroblasts and enzymatically digested by collagenase. Therefore, the quantitative alteration of collagen depends on the balance of synthesis and digestion. Skin is always exposed to oxygen stress and is suggested to be frequently generated the reactive oxygen species (ROS). We investigated the effect of ROS induced by xanthine-xanthine oxidase system on collagen production and collagenase activity in cultured human dermal fibroblasts. Collagen synthesis which was assessed by measuring 3H-proline incorporation into extracellular collagen, was decreased by ROS exposure. Collagenase activity was measured by using DNP-peptide as a synthetic substrate of collagen and increased by ROS exposure. These changes supported the biological alteration of collagen observed in photoaging skin. Extracts of Chouji and Gennosyouko which have superoxide-scavenging activity, prevented the ROS-induced changes significantly. These results suggest that ROS may be one of the factors which cause the decrease of collagen observed in photoaging skin.
  • 渡辺 真理奈, 中田 功二, 門司 和美, 苗代 英一, 牧野 武利
    1994 年 28 巻 2 号 p. 178-182
    発行日: 1994/09/15
    公開日: 2010/08/06
    ジャーナル フリー
    Recently, it was reported that the topical application of H2O extract of mugwort [Artemisia princeps P.] effectively prevents the itching and the inflammatory responses. However, its pharmacological mechanism is unclear. In order to clarify some of the active ingredients and their pharmacological effects, we examined in vitro and in vivo anti-inflammatory effects of the H2O extract and its fractionated parts of mugwort. The fractionation was carried out on a method of liquid-liquid partition with H2O-n-BuOH, and further reprecipitation on the concentrated H2O layer from H2O-EtOH. The fraction obtained as a precipitate significantly inhibited histamine release from rat peritoneal mast cells induced by compound 48/80. The topical application of this fraction also significantly inhibited (1) the hind paw edema induced by compound 48/80 and (2) the vascular permeability enhanced by the intradermal injection of histamine and serotonin. These results demonstrated that the anti-histamine components obtained in the fraction of water soluble and ethanol insoluble phase showed an anti-inflammatory effect.
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