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Volume 18 (1949)
- Issue 4 Pages 78-
- Issue 3 Pages 57-
- Issue 2 Pages 29-
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Volume 18, Issue 4
Displaying 1-8 of 8 articles from this issue
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Tsuruo Ichihara1949 Volume 18 Issue 4 Pages 78-81
Published: November 20, 1949
Released on J-STAGE: June 30, 2008
JOURNAL FREE ACCESSThe author has investigated the anti-discoloring quality of Mycobacterium in murine leprosy granulomas while he was treating them with Tellur, Tellur added murine leprosy vaccine and murine leprosy bacillus vaccine. The Tellur added murine leprosy vaccine group showed the weakest anti-diseoloring quality, the Tellur group came next. The murine leprosy vaccine group showed a little stronger anti-discoloring quality than the others.
This fact shows, the more the possibility of recovery, the weaker anti-discoloring quality.View full abstractDownload PDF (371K) -
Toshio Yoshinaga1949 Volume 18 Issue 4 Pages 82-85
Published: November 20, 1949
Released on J-STAGE: June 30, 2008
JOURNAL FREE ACCESSThe complement fixation reaction was made on lepra serum with Lecithin and Kephalin both of which had been extracted from leproma and murine leprosy granuloma with the following results:
1) Lecithin showed about the same positive percentage (35.3%) of yolk Lecithin.
2) Kephalin showed 17-24% lower rate than ox-brain Kephalin posive rate (68.0%).
3) Ox-brain Kephalin had a priority as a non-specific reaction antigen. Kephalin of lepra tissue was of little value.
4) For a rabbit immune serum of Mycobacterium leprae, Lecithin, Kephalin from leproma had a higher positive rate than that from murine leprosy granuloma, for rabbit immune serum of Mycobacterium leprae murium Lecithin, Kephalin from murine leprosy were higher than that from human leprosy.
5) Kephalin showed a higher positve rate than Lecithin.View full abstractDownload PDF (336K) -
Kumeo Ogawa1949 Volume 18 Issue 4 Pages 86-92
Published: November 20, 1949
Released on J-STAGE: June 30, 2008
JOURNAL FREE ACCESSBy using various solid culture media many attempts have been made to cultivate Mycobacterium leprae murium, while a few attempts have been made to cultivate Myoobacterium leprae.
Blood agar, Ueda culture medium, Kirchner blood agar Urabe Kaku culture medium, Mucin added potato culture medium, and Glucesamin serum agar were successful in incereasing the production of the mycobacterium. However, none of them could be transmitfeb through generations.View full abstractDownload PDF (614K) -
Kumeo Ogawa1949 Volume 18 Issue 4 Pages 93-101
Published: November 20, 1949
Released on J-STAGE: June 30, 2008
JOURNAL FREE ACCESSSome experimentions were made to accelerate the development of murine leprosy in a white mouse, while others were made to raise the perceptivity of Mycobacterium leprae to a mouse. The results obtained are as follows:
1) Eosin, erythrosin, when applied to the inoculated region greatly accelerated the development of murine leprosy while haematoporphyrin, fluorescein and bergamot oil did not show this reaciton.
2) The inoculation of Mycobacterium leprae murium added with cow sub-maxplary gland Mucin accelelerated the symptom to develope.
3) The joint inoculation of non-pathogenic acid fast agents (No. 421) to a mouse accelerated the symptom to develope.
4) The inoculation of Mycobaoterium leprae, egg yolk and non-pathogenic agents (No. 421) to a mouse stimulated the growth of lepra abnormality to a small extent. However tnis reaction could not be transmitted through generations.View full abstractDownload PDF (648K) -
Kihei Tanioku, [in Japanese]1949 Volume 18 Issue 4 Pages 102-105
Published: November 20, 1949
Released on J-STAGE: June 30, 2008
JOURNAL FREE ACCESSLight 60 cases were treated with Promin, Diazon and Protozol respectively as well as combined together. In all cases the injection of a large mount at the early stage of the disease was found favorable. Above all the administration of both Promin and Diazon together with Ferrum reductum against anemia was most favorable.View full abstractDownload PDF (322K) -
Keizo Nakamura, Masayoshi Endo1949 Volume 18 Issue 4 Pages 106-108
Published: November 20, 1949
Released on J-STAGE: June 30, 2008
JOURNAL FREE ACCESSOur newly devised method on the cultivation of the leprosy bacillus and its results were descrived before in detail, (Nakamura and Endo 1949). Since then, up to the 30th November 1949, the subcultulture of the leprosy bacilli had been successful. Namely;View full abstractDownload PDF (285K) -
MYCOBACTERIUM LEPRAE MURIUM BY MEANS OF NAKAMURA ENDO MUCIN CULTURE MEDIUMShinji Nishimura, Hajime Honda1949 Volume 18 Issue 4 Pages 109-116
Published: November 20, 1949
Released on J-STAGE: June 30, 2008
JOURNAL FREE ACCESSWe made 76 liquid culture media out of cow submaxillary Mucin made in our laboratory. Using them we tried to cultivate murine leprosy Kumamoto strain for 71. times, Fukuoka strain for 49 times and human leprosy 11 strain for 93 times. In all cases we recognized no increase of both Mycobacterium leprae and Mycobacterium leprae murium. But we got an encouraging suggestion by Bacillus tuberculosis cultivation by No. 65 culture medium which showed a remarkable growth of the bacilli. So we are making the following experimentation.View full abstractDownload PDF (528K) -
Yoshimasa Watanabe, Chie Watanabe1949 Volume 18 Issue 4 Pages 117-122
Published: November 20, 1949
Released on J-STAGE: June 30, 2008
JOURNAL FREE ACCESSFirst we cultivated Mycobacterium leprae murium on Nakamura Endo Mucin culture medium and a similar culture medium. Animals were inoculated with this mycobacterium with the following result.
In a Mucin added liquid culture medium, we could percive the existence of the mycobacterium for a considerably long period. But we could not define exactly if the organisms had been produced and cultivated there or they gathered together where they had been throne in. When a great number of Mycobacterium leprae murium were inoculated into whit, rats, some of them produced lepromas while others didnot.We have come to a conclusion that Myc-obacterium leprae murium can exist in a Mucin culture medium longer than is usually supposed.View full abstractDownload PDF (398K)
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