I examied the serum protein of thb leprous patents with buret reaction and colorimetry, the results were as following:
1. With tubercle leprosy albumin decreases and globulin increases, compared with the sound serum. With nerve and macula lepra no change was found.
2. Albumin/globulin was more than 1.0 with nerve and macula leprosy, and less than 1.0 with tubercle leprosy.
3. The volume of α. and β globulin was not different in every type, but α-globulin increased in tubercle leprosy.
4. One factor which accelerated blood cells sedimentation in leprosy was globulin.
5. The chief factor of positive of. Takada reaction in leprosy was the increase of γ globulin.
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