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Volume 44 (1975)
- Issue 4 Pages 193-
- Issue 3 Pages 129-
- Issue 2 Pages 49-
- Issue 1 Pages 1-
Volume 44, Issue 3
Displaying 1-6 of 6 articles from this issue
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I. On the Alteration in Organ Lipoid Contents of Murine- Leprous Mice and RatsToshio YOSHINAGA1975 Volume 44 Issue 3 Pages 129-136
Published: September 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSOrgan lipoid contents of murine-leprous mice and rats were compared respectively with those of normal cases. The results were as follows.
1) The content of organ triglycerides in the murine-leprous mice showed a decrease.
2) This decrase was remarkable in the spleen, liver, and kidney.
3) The content of organ phospholipids in the murine-leprous mice generally showed an increase.
4) This increase was remarkable in the spleen, liver and kidney.
5) No clear alteration in the content of organ total cholesterol could be found in every organ of the murine-leprous mice.
5) The tendency in the alteration of organ lipoid content by murine-leprous rats was almost similar to that in the aforesaid mice cases, throughout triglycerides, phos- pholipids, and total cholesterol.View full abstractDownload PDF (789K) -
II. On the Alteration in Organ Lipoid Content of Experimental Tuberculosis by Guinea-pigToshio YOSHINAGA1975 Volume 44 Issue 3 Pages 137-141
Published: September 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSOrgan lipoid content of tuberculous giunea-pigs was compared with that of normal cases. The results were as follows.
1) The content of organ triglycerides in the tuberculous guinea-pigs generally showed a decreases.
2) This decrease was remarkable in the spleen, liver, and kidney.
3) The content of organ phospholipids in the tuberculous guinea-pigs generally showed an increase.
4) This increase was remarkable in the lung, spleen, and kidney.
5) The alteration of organ total cholesterol content in the tuberculous guinea-pigs was not shown so remarkably as that of triglycerides and phospholipids, but a small decrease was shown in the liver and the lung.View full abstractDownload PDF (558K) -
Chozo HASHIZUME1975 Volume 44 Issue 3 Pages 142-149
Published: September 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSA series of twelve leprosy patients with forefoot amputation, talipes equinovarus-type contracture or a marked degree of destruction of the tissues adjacent to the ankle-joint ar of the tarsal region, with an extensive incurable ulcer, were treated surgically by Chopart's amputation combined with resection of the talus and with coaptation of the calcaneus to the tibia. Six months to a little over years after the operation, the patients show an average foot contraction of 4cm and are capable of walking along bare-foot within the walls. There is no evidence of ulcer in 10 of the cases and they are now quite able to walk to distant places with the aid of an artificial limb. With the combfined surgical treatment, not only does the patient become able to stand and with bare feet but also may the stump or the base of the calcaneus be maintained more physiologically with remarkable firmness than With the case of Syme's amputation which usually provides only an uncertain degree of correction for a paralyzed leg. The method described is considered preferable particularly for the treatment of affected legs in leprosy patients who tend to develop ulceration.View full abstractDownload PDF (1204K) -
The 2nd Report: On the Geographical StatusKazuo SAIKAWA1975 Volume 44 Issue 3 Pages 150-162
Published: September 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSThe leprosy epidemiological status on four areas in the Ryukyu Island, mainland Okinawa, Okinawa Islands Miyako Archipelago and Yaeyama Archipelago is analyzed by Leprosy Prevalence Rate (P.R.), Incidence Rate (I.R.), Lepromatous Incidence Rate (L.I.R.), Lepromatous Ratio (L.Ratio) and Percentage of Onset Age which were collected from 1931 to 1974. The assessment on the data shows that the different epidemiological situation is observed in four areas. The average P.R. and I.R. in the Island is 1.81o/oo and 2.28.o/oo. The P.R., I.R. and L. Ratio of Irabu Village in Miyako Archipelago, the highest leprosy endemic village, in 1974 were 10.10o/oo, 2.0o/oo and 0.44o/o. On the contrary these rates in Ginowan City of the central part of mainland Okinawa were 0.38o/oo, 0.01 o/oo and 0o/o. Generally the decline of leprosy occurence is observed in three areas except Miyako Archipelago at the present time. Especially the epidemio- logical situation in Nakazato village in Okinawa Island has been improved very much since 1966, i.e. it's I.R. was 0.84o/oo and L.I.R. 0.44o/oo in 1950 but I.R. was 0.27o/oo and L.I.R. 0.05o/oo in 1974. The highest leprosy endemic area in the Island is Miyako Archipelago where P.R. is 6.47o/oo, I.R. 0.45o/oo, L.I.R. 0.18o/oo and L.Ratio 40% in 1975. Leprosy disease in Miyako Archipelago is one of the most important problems and its control program should be done on the level of public health services.View full abstractDownload PDF (1136K) -
Tsunehiko HIRATA, Tetsu NAKAYAMA1975 Volume 44 Issue 3 Pages 163-176
Published: September 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSElectron microscopical studies on the cellular organelle of M. leprae were done in comparative cyto-morphological method. The outlines of main subjects were briefly described below.
1. Peripheral parts of the bacilli The peripheral parts of the bacilli were divided into 3 layers; (a) the capsular struc- ture, (b) the cell wall, and (c) the cytoplasmic membrane. The capsular structure of M. leprae was more thin than that of M. lepraemurium.
2. Intra-cytoplasmic organelle In cytoplasm of the bacilli, two kinds organelle-the intracellular membranous orga- nelle (mesosomes) and the electron-dense or -homogenous grnules-were found typically.
3. Cell division process In active bacilli, the mesosomes were observed generally at or near the cell divisionn site, and they seemed to play the significant role in cell division process.
4. Other organelle in Lepra-cell The large electron-dense and -homogenous bodies were found outside the bacilli, and in these bodies the small electron-dense granules were observed. It was assumed that these bodies were originated from the bacilli and "L-form theory" or "Life cycle hypothesis" was adopted for explaining their exsistences and organisations. Further investigation should be made in the future on this problem.View full abstractDownload PDF (2712K) -
Tsunehiko HIRATA, Tetsu NAKAYAMA1975 Volume 44 Issue 3 Pages 177-186
Published: September 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSDynamic investigations of M. leprae inoculated and grown in mouse foot-pads were studied in cyto-morphological method at the ultrastructural level. In the experimentally infected mouse foot-pads, the large electron dense- and homo- genous-bodies were frequently found outside the bacilli, and the small electron-dense granules were observed in these bodies. These observations might show the pleomorphism of M. leprae, and the L-form theory was adopted for explaining about the existence of the granules above mentioned. These bodies and/or granules were never found in normal mouse foot-pads.View full abstractDownload PDF (1420K)
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