Repura
Online ISSN : 2185-1352
Print ISSN : 0024-1008
ISSN-L : 0024-1008
Volume 33, Issue 3
Displaying 1-11 of 11 articles from this issue
  • SABURO UYEDA
    1964 Volume 33 Issue 3 Pages 169-174
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    En étalant sans etre agité du jus pressé des tissus de la lepre humaine et murine, on a remarqué que (1) Ces deux sortes de germes lépreux se sont présentés toujours en formant un certain arrangement caractéristique composé de vrais filaments mycéliens plus ou moins longs avec de nombreuses ramifications. (2) Du point de vue de leur morphologie, les germes lépreux semblent ne pas appartenir au Genre Mycobacterium, mais à un autre Genre qui doit etre établi à nouveau dans le voisinage du Genre Nocardia dans la Famille Actinomycétacées. (3) Pour discuter le polymorphisme de ces germes, it faut bien remarquer au préalable le fait que l'arrangement caractéristique qu'ils forment suivant leur developpement, est composé toujours de germes de formes variées, c'est-à-dire de formes longues, courtes, ramifiées, etc. (4) Les observations exécutées nous suggéraient probablement qu'il sera peut-etre possible de juger une culture comme positive, lorsqu'elle est composée de germes se mettant en ordre dans un certain arrangement pareilà celui quiaété observe, comme ci-dessous, dans l'étalement de tissus de lésions lépreuses.
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  • SABURO UYEDA
    1964 Volume 33 Issue 3 Pages 175-180
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    L'émulsion dense des tissus broyés de rats blancs attenints a été cultivée, Bans le milieu de Kirchner, sur une lame qui a été deposée dans une boite de verre fermée hermétiquement et humide. (1) Le fait important et commun à tous les cas était que sur les lames mises à 30°C les germes de formes un peu Tongues se sont évolués au cours des semaines, en formant graduellement nombre de petits groupements dans lesquels ils ont composé avec les formes courtes un certain arrangement caractéristique pareil à celui que l'on avait observé déja dans les frottis des tissus lépreux dans notre dernier rapport. De ce fait, it sera possible de conclure que ces groupements formés sur les lames, quoiqu'ils étaient tout petits, peuvent etre le produit de développement in vitro de ce microbe. (2) Du point de vue de la morphologie et de l'arrangement caractéristique que ce microbe a montré en développant sur les lames, it n'y aura plus de doute que ce microbe n'appartienne pas au Genre Mycooacterium, mais à un autre Genre qui dvit etre etabli à nouveau dans le voisinage du Genre Nocardia dans la Famille Actinomycétacées. (3) Le developpement à 30°C a été tounjours un peu supérieur que celui à 37°C. Cela peut-etre indiquera que ce microbe peut se développer selon des variaitons de température plus ou moins grandes.
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  • Chiefly Seconday Cataract
    KIKUO HAYASHI
    1964 Volume 33 Issue 3 Pages 181-186
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    From 1959 to 1962 the author operated 204 eyes of leprosy patients (chiefly secondary cataract) in 3 leprosaria in Japan. An observation was kept on the operated eyes for three years and a half past and the results were obtained, as fallows:
    1. 82% of the operated eyes were improved in their visual acuity.
    2. 35% of 130 eyes which were improved, aggravated again within three years and a half.
    3. Main causes of aggravation were Opatitas Cornae due to Lagophthalmos, Occculusio Pupillae by Uveitis, Glancoma, Hyphaema and Chorioretinitis.
    4. An intimate relationship was found between aggravation of leprosy and visual acuity. That is; many of those who aggravated in the ducai condition lowered their visual acuity.
    5. Such followings seemed to be the possible hindrances of improving visual acuity as outflow of vitreous-body, over-iridectomy, remains of Nucleus, Cortex, Capsula lentis, imcomplete suture of the wound, Hyphaema, Abcessus corporis vitrei, Luxatio lentis and explosive bleeding.
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  • KIKUO HAYSHI
    1964 Volume 33 Issue 3 Pages 189-191
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    The present report describes the comparison of ophthalmic symptoms of lprosy observed in 3 leprosaria in Japan (notrth, middle and south). Ophthalmic symptoms of leprosy in the north leprosarium were more severe than those in the south leprosarium. Furthermore, in the case of the leprosy patients born in the same district, those who lived in the north leprosarium were more severe than those in the south leprosarium. Details were as follow:
    1. Comparison of the depilation of eyebrow of L. type 82% in the north, 65% in the middle 56% in the south
    2. Comparison of the Uveitis of L. type 74% in the north, 66% in the middle 47% in the south
    3. Comparison of the secondary cataract of L. type 23% in the north, 20% in the middle 11% in the south
    4. Comparison of Opacit_??_.s Cornea 23% in the north, 19% in the middle 13% in the south
    5. Comparison of Lagophthalmus 47% in the north, 38% in the middle 25% in the sonth
    6. Percentage of Lagophthalmus of L. type was higher than that of tuberculoid type.
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  • FUMINORI KANETSUNA, ENJIRO TODA, JUN OGAWA, MITSUGU NISHIURA
    1964 Volume 33 Issue 3 Pages 192-196
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    Various amounts of human leprosy bacilli were inoculated subcutaneously or intraperitoneally into 205 (175 inoculated with leprosy bacilli and 30 with heat-killed bacilli as controls) newborn golden hamsters, within 24 hours after birth. All inoculated hamsters did not show any mycobacterial lesions, both macroscopically and microscopically.
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  • VI. Effects of Physical treatments on the infectivity of Myc. lepraemurium
    MASAHIRO NAKAMURA
    1964 Volume 33 Issue 3 Pages 197-199
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    Department of Microbiology, Kurume University School of Medicine Kurume, Japan The effects of heating, ultraviolet irradiation, and agitation on the infectious activity of Myc. lepraemurium were investigated. The results obtained showed that the infectious activity of the bacillus was completely inactivated by heating at 55°C for 30 min, or by exposure at a distance of 15cm for 120min. to a germicidal lamp (Shimazu GL-15). Furthermore, the infectivity of the bacillus was lost by agitation. (90/min) in a water-bath at 37°C for 5 days, whereas it was maintained for 10 days under the stationary condition.
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  • SHINJI NISHIMURA, KENJI KOHSAKA, YOSHIKO HIROSE, YOICHIR KAWAGUCHI
    1964 Volume 33 Issue 3 Pages 200-205
    Published: July 30, 1964
    Released on J-STAGE: June 30, 2008
    JOURNAL FREE ACCESS
    From the fact that this bacillus is present in a state of compatibility with the histiocyte in the host, it is suggested that the organism itself does not have a strong toxicity. In order to determine the virulence, therefore, the quantity of bacilli required to kill the host should not be taken as the index but evaluation should be based on the laproma development at the inoculation site.
    A comparative study has been made on the virulence of the Kumamoto, Keishicho, Kurume-42, Fukuoka-1, Hawaiian, Douglas and Odessa strains.
    Two strains of mouse with differing susceptibility, C3H (onset delayed but leproma large) and C57BL6 (onset rapid but leproma small), were used. The strains of bacilli had been maintained for more than 10 generations in mice under the same conditions. Leproma emulsions of each strain were prepared, .
    0.25ml of 10-2-10-3 diluted solution inoculated subcutaneously and the size of the leproma produced was measured up to 20 weeks. The animals were then sacrificed and the leproma weighed. The distribution of bacilli to the organs was also examined.
    As can be seen in the table, no significant difference was noted between the 7 strains.
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  • Tomosaburo Ogata
    1964 Volume 33 Issue 3 Pages 206-210
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    he authors reported that the relationship was recognized in some points between leprosy and tuberculosis, and that BCG-vaccination would be effective for the prevention of leprosy. Therefore, the influence of tuberculin allergy before the occurrance of leprosy upon the clinical symptoms of leprosy was investigated in leprosy patients. The patients examined was 1, 229 cases with the age of less than 35 old years, who would be influenced by BCGvaccination in Japan. The examined cases were divided in three groups by the positivity of tuberculin reaction and BCG-vaccination, and then, the clinical type, stage and symptom of leprosy at the entrance into leprosaria and at present was compared in these three groups. As a result, the influence of the positivity to tuberculin reaction before the occurrance of leprosy upon the clinical symptoms of leprosy before or after the entrance into leprosaria could not be recognized.
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  • [in Japanese]
    1964 Volume 33 Issue 3 Pages 211-213
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    Download PDF (964K)
  • [in Japanese]
    1964 Volume 33 Issue 3 Pages 214-221
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    Download PDF (1164K)
  • [in Japanese]
    1964 Volume 33 Issue 3 Pages 221-222
    Published: July 30, 1964
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    Download PDF (273K)
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