Repura
Online ISSN : 2185-1352
Print ISSN : 0024-1008
ISSN-L : 0024-1008
Volume 21, Issue 1
Displaying 1-6 of 6 articles from this issue
  • Saburo Sato, Akira Mayama
    1952 Volume 21 Issue 1 Pages 1-5
    Published: 1952
    Released on J-STAGE: December 10, 2008
    JOURNAL FREE ACCESS
    Syringomyelia is a comparatively rare disease and is difficult to distinguish from certain cace of neural Leprosy. The authors recognized two cases, one is a 48 years old farmar's wife who was complaining of sensory, motory and trophic disturbances of the upper extremities with ape-hands, since a half year; the other is a 39 years old woman who was suffering from sensory, motory and trophic disturbances of four extremities with ape-hands, talipes equinovarus and kyphosis. She showed pupillary symptoms such as anisocoria and stiff pupil accompanying Homer's syndrome, since about 20 years. In the latter case, the left auricular nerve and the skin of the right forearm were examined biopsically, but none of them showed any bacteriological or histological changes.
    The said cases were scrutinized, comparing with 49 cases, reported hither to in Japan, especially in regard to sex, age, favourite localization, cardinal symtomes, such as sensory, motory and trophic disturbances, deformity of the extremities or vertebral column and pupillary symtomes etc.
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  • Masashi Namba, Hiroshi Fujiwara
    1952 Volume 21 Issue 1 Pages 5-10
    Published: January 20, 1952
    Released on J-STAGE: June 30, 2008
    JOURNAL FREE ACCESS
    In this experiment, the serum proteins of each types or Leprosy were analysed with Tiselius's apparatus.
    1) No remarkable change was seen in lepra maculosa and 1. nervosa except a slight increase of γ-globulin.
    2) In lepra tuberosa γ globulin increased stolongly. And in some cases albumin increased.
    3) In erythema nodosum which occured in lepra tuberosa γ globulin increased as much as in lepra tubesosa, and marked decrease of albumin and increase of α and β globulin were seen.
    4) In the so-called second nervous leprosy almost the same changes were seen as in lepra maculonervosa.
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  • Tadao Toda, Shinya Otomo, Yo Nakakawa, Masahiro Nakamura
    1952 Volume 21 Issue 1 Pages 11-17
    Published: January 20, 1952
    Released on J-STAGE: June 30, 2008
    JOURNAL FREE ACCESS
    1) The addition of amino-delivates to the media seems to give a favorable effect for multiplication of bacilli.
    2) We advocated as the judging method of successive culture, to describe the size and number of microscopic colonies at every generation, and to regard the increase of the size and number as positive.
    3) By this judging, our culture of the leprosy bacilli were successful to second generation.
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  • Kenji Yasumoto
    1952 Volume 21 Issue 1 Pages 18-22
    Published: January 20, 1952
    Released on J-STAGE: June 30, 2008
    JOURNAL FREE ACCESS
    The K. F. of the acid-fast bacteria was the strongest in the period where they were stainded strongly by Ziehl and their growth was vigorous. It was also stronger when we had double no staining. The pH of the boiling water influenced on the K. F., that is, strongest in neutral, and weaker in acid or alkaline. Among the neutral waters, it is stronger with destilled water than with pipe-water or physiologicol salt solution. Therefore, destilled water seems the best to examine the K. F.
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  • Studies on the Rat-Leprosy. (19)
    Kenji Yasumoto, Tsuneyoshi Hiramoto
    1952 Volume 21 Issue 1 Pages 23-25
    Published: January 20, 1952
    Released on J-STAGE: June 30, 2008
    JOURNAL FREE ACCESS
    The therapeutic efficacies of Tibione, PAS & Streptomycin, especially of their combinations on the development of rat-leprosy, were studied.
    The results were as follows: The development of the leprous granuloma showed the order as Tb1+SM_??_PAS+SM⟨SM⟨Tb1_??_PAS⟨Tb1+PAS⟨Controls,
    In general, the therapeutic actions of drugs, tested, were rather silght, but streptomycin when combined with tibione afforded the most remarkable effect.
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  • Shinji Nishimura, Michiyuki Kono, Nobuhiko Aoyama, Takeyo Takahashi
    1952 Volume 21 Issue 1 Pages 26-29
    Published: January 20, 1952
    Released on J-STAGE: June 30, 2008
    JOURNAL FREE ACCESS
    0.1-0.2mg Tibione per day, soluted in ethylenglycocol, was injected subcutaneously for six consective days in a week to a group of rats which developped leprosy and to another group which did not develop lesions. The ulcer of the lesion-developing group was cured rapidly, but the lepromata showed no regressive change. In the other group which had been inoculated and showed no lesin, it could not control the onset of lesion in animals injected both with 1/200g and with 1/20000g or leproma. Namely, it is effective on leprous ulcer, but could not make lepromata disappear.
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