All issues
Volume 44 (1975)
- Issue 4 Pages 193-
- Issue 3 Pages 129-
- Issue 2 Pages 49-
- Issue 1 Pages 1-
Volume 44, Issue 4
Displaying 1-6 of 6 articles from this issue
- |<
- <
- 1
- >
- >|
-
HIDEO TAKIZAWA, SUSUMU ADACHI, KENTARO MATSUMOTO, TARO KAKITANI1975 Volume 44 Issue 4 Pages 193-198
Published: December 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSFifty five cases of all 64 out-patients with HD in Kyoto Prefecture could be followed up.(Eleven cases of them were dead. Two cases were readmitted to leprosaria.) Their ages ranged from 28 years to 88 years (mean 54.3). About 61% of them were over 50 years old.
Eight cases of 30 lepromatous or borderline cases (26.7%) experienced relapse in their course.The period of time from bacterial negativity to relapse were 3 years to 13 years. Some troubles of patients and the control problem of HD in Japan was discussed briefly.View full abstractDownload PDF (625K) -
SHIGENORI ISHIHARA1975 Volume 44 Issue 4 Pages 199-201
Published: December 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSA male patient aged 75, had complained of the paresthesia on the both sole about ten years ago. He noticed the nodules on bilateral earlobes, and swelling of the face at 1970. He had been not registered as leprosy, and had been treated as a heart disease until Oct. 1973.
On that time he had been diagnosed as lepromatous leprosy and admitted to National Suruga Leprosarium. The patient had remarkable lepromatous lesions in the oral cavity, uvula, soft and hard palate and tongue together with skin lesions.
One of the lepromas of the tongue, sized 3mm×4mm, was taken off surgically and it was observed histopathologically. The mucous membrane is thinner than usual without rate pegs.Submucous tissue is occupied by masses of leprous infiltration, without "free zone ". And the leprous infiltration invade into the muscle tissue of the tongue. The much acid fast bacilli are detected in the leproma.
Since he has been treated over one year with DDS, lepromas of the tongue clinically disappeared, and also the sense of taste has gradually recovered.View full abstractDownload PDF (908K) -
KAZUO SAIKAWA1975 Volume 44 Issue 4 Pages 202-208
Published: December 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSIn Okinawa Leprosy Out-patient Treatment started in 1962, since then many patients in the field including new patients and escapees from leprosaria have received treatment in leprosy out patient departments. Moreever early leprosy diagnosis, early treatment, follow-up of discharged patients and contact tracing for house-hold have been strongly performed for thirteen years in O. P. D. The recentry improvement of leprosy epidemiological status in Okinawa is the outcome of leprosy control policy based on out-patient treatment.
The following points should be emphasized to expand leprosy control program there;
1. The major problem in Out-patient care is to ensure regularity of treatment and spacially the priority should be given to the follow-up of Lepromatous and Borderline Leprosy patients.
2. More relapse cases of Lepromatous and Borderline leprosy have been observed than Tuberculoid and Indeterminate leprosy.
3. To prevent relapse the priority should be emphasized to follow-up Lepromatous and Borderline leprosy patients who were discharged from leprosaria.View full abstractDownload PDF (865K) -
TSUNEHIKO HIRATA1975 Volume 44 Issue 4 Pages 209-213
Published: December 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSThe effect of INH and DDS on the capsular structure of M. lepraemurium was studied at the light and the electron microscopical level.
Both drags did not have an effect on the capsular structure.
However, the bacilli were proved to be susceptible to INH and not to DDS. The cytoplasm of M. lepraemurium adminstrated INH was collapsed and Vacuolated.View full abstractDownload PDF (2553K) -
I. Isolation Frequency and Biological Properties of the OrganismsTSUNEHIKO HIRAT1975 Volume 44 Issue 4 Pages 214-220
Published: December 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSThe observations reported here are concerned with the microbiological studies on the cultivable acid-fast organisms from the leprosy materials.
Most materials were repeatedly washed in sterile saline solution and aqueous solution containing 8.0% of NaOH, and inoculated onto an egg-yolk medium and incubated at 33°C for 3-5 weeks.The colony of cultivated organisms was grey or orange-yellow.
The isolation frequency of cultivated acid-fast organisms from materials was 0%, 17.4%, 25.0%, 28.6% and 90.0% in case of ear-lobe leproma, subcutaneous leproma, nasal mucosa, nasal crusta and nasal washings respectively.
The biological properties of the organisms were not so much different from that of the atypical mycobacteria. However, the organisms showed remarkable morphological changes during the cultivation, especially in their elongation, cytoplasmic granulation and other phenomena, which were not common with other mycobacteria.View full abstractDownload PDF (1729K) -
HIROKO ENDO1975 Volume 44 Issue 4 Pages 221-232
Published: December 30, 1975
Released on J-STAGE: December 10, 2008
JOURNAL FREE ACCESSIt is well-known that there are not a few strains of acid-fast bacilli developing visible growths on ordinary culture media, during attempts to cultivate leprosy bacilli, and most of them are merely regarded as contaminants. Mycobacterium KNBE strain, which had been isolated by T. NAKAYAMA from a subcutaneous nodular lesion in murine leprosy mouse, was, however, speculated as a variant of the causative agent.
The author studied the biological characters of this strain and found that its growth and elongation were accelerated by some kinds of peptone.
Based on the speculation that this strain might have some metabolic relations to murine leprosy bacilli, and with the ultimate aim to cultivate leprosy bacilli, the growth factor was isolated from a proteose peptone which had proved to show the above-mentioned activities.
This substance was estimated to possess a covalent bond with L-methionyl-L-leucine and Cu ion. And it was also demonstrated that a synthetic L-methonyl-L-leucine preparation had a similar effect on the strain.
From these results, it is concluded that the specific effects of the substance obtained from a proteose peptone depends on L-methionyl-L-leucine.View full abstractDownload PDF (2853K)
- |<
- <
- 1
- >
- >|