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Volume 54, Issue 11
Displaying 1-3 of 3 articles from this issue
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...2001 Volume 54 Issue 11 Pages 541-564
Published: November 25, 2001
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESSDownload PDF (17251K) -
[in Japanese], [in Japanese], [in Japanese]2001 Volume 54 Issue 11 Pages 565-570
Published: November 25, 2001
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESSDownload PDF (6996K) -
MUNEO HIKIDA, SAYAKA TERASHIMA, YUKO SATO, RYOUICHI OKAMOTO, MATSUHISA ...2001 Volume 54 Issue 11 Pages 571-579
Published: November 25, 2001
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESSComparative antibacterial activity of imipenem (IPM), panipenem (PAPM), meropenem (MEPM) and biapenem (BIPM) was determined against 288 clinical isolates of P aeruginosa collected from various hospitals in 2000. The order of activity by comparison of MIC50/MIC80/MIC90 was: MEPM (1/4/8 μg/ml) >BIPM (1/4/16 μg/ml) >IPM (2/4/16 μg/ml) >PAPM (8/16/32 μg/ml). Moreover, the order of activity against 75 strains of P aeruginosa (MIC of CAZ, AZT was≥16μ/ml and MIC of IPM, MEPM was ≤_8μg/ml) by comparison of MIC50/MIC80/MIC90 was: BIPM (1/2/8 μg/ml)≥MEPM (1/4/8 μg/ml)≥ IPM (2/2/8 μg/ml) >PAPM (8/16/16 μg/ml). Judging from both correlation between the MICs of carbapenems and relationship between class C β-lactamase activity and drug susceptibility of carbapenems, it becomes apparent that carbapenems, especially BIPM and MEPM will be useful for treatment of antipseudomonal cephem resistant pseudomonas infection.View full abstractDownload PDF (2008K)
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