Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Volume 31, Issue 1
Displaying 1-17 of 17 articles from this issue
  • Correlation between histological findings and prognosis
    Kazuo SANO, Tsugio INOKUCHI, Hitoaki NAKAMURA, Akira KITAMURA, Motomas ...
    1985 Volume 31 Issue 1 Pages 1-9
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Forty-six patients with oral squamous cell carcinoma were reviewed clinicopathologically. A histological classification was performed on the initial biopsies prior to treatment, and the correlation between histological factors and prognosis was investigated.
    Four different histological factors (Differentiation, Nuclear polymorphism, Mitoses and Cellular response) were evaluated and scored on a three-point scale. Total points of each case in this series were distributed from 4 to 10 points and divided into three classes: low grade malignancy (4-6 points), middle grade (7-9 points) and high grade (10-12 points).
    The high grade malignancy cases indicated poor prognoses compared with those of low grade. Differentiation of tumor cell may be a significant factor in determining histological grade of malignancy has been suggested.
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  • Nuclear DNA content and nuclear area in pleomorphic adenoma
    Yukihiko KINOSHITA, Kaizo SHIMURA, Tomoichi SATO, Yoshinao FUJTWARA, N ...
    1985 Volume 31 Issue 1 Pages 10-20
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    This study was performed to obtain indices for clinically determining the degree of malignancy of pleomorphic adenomas. Nuclear DNA content and nuclear area of tumor cells were measured and analyzed in comparison with clinical and pathological observations.
    Twenty-four cases of pleomorphic adenoma were studied. A control group consisted of seven cases of normal salivary gland, two cases of adenolymphoma, and five cases of malignant salivary gland tumor. Most of the cells were isolated from slices of paraffin embedded tumor masses removed from patients. Some cell samples were obtained from imprints of biopsy specimens. Following Feulgen staining, the nuclear DNA content and nuclear area were simultaneously measured with Vickers M86 scanning microdensitometer. The nuclear DNA content of the epithelial cells was calculated with the nuclear DNA content of a control lymphocyte put at 2.0c.
    The results were as follows:
    1) The DNA histogram of normal salivary gland showed one distinct peak at 2.0-2.5c. Cells with nuclear DNA content over 4.0c were not observed. The measurements of the nuclear area were distributed in and around the region of 30μ2.
    2) In one case of adenolymphoma, the DNA histogram and the DNA-area scattergram showed a similar pattern to those of normal salivary gland cells. In another case, a small population of cells over 4.0c was observed and cells diffused slightly on the scattergram.
    3) In the cases of malignant salivary tumor, the average values and the variances of the nuclear DNA content increased generally. Hyperploid cells over 4.0c and aneuploid cells were observed. The DNA histogram showed a shift rightward from normal modal C value, bi-peak or poly-peak. The scattergram showed a remarkable diffusion and a high correlation.
    4) In the cases of pleomorphic adenoma, measurements of the nuclear DNA content and the nuclear area varied greatly, ranging from those close to the values of normal salivary gland to the values of malignant salivary tumor. The average values and the variances of the nuclear DNA content as well as the number of cells over 4.0c were apt to increase in patients who showed rapid progress of tumorgenesis, predominance of a solid pattern of tumor cells histologically and prolifelation like cords. Particularly in the cases where the measurements of the nuclear DNA content and the nuclear area resembled those of malignant salivary gland tumor, malignant potential tended to be high.
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  • Manabu OKAMOTO, Yasuharu TAKENOSHITA, Teturo KABAYAMA, Hideo TASHIRO, ...
    1985 Volume 31 Issue 1 Pages 21-28
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    It is sometimes difficult to assess the facial deformity associated with multiple mandibular fractures, especially in swollen cases shortly after injuries. Widening of the intergonial distance is often caused by parasymphyseal and bilateral condylar fractures of the mandible.
    In our recent experience, 9 out of 10 cases with the above type fractures showed some degree of widening deformity on the lower face. These deformities sometimes remained and were complained of by patients after treatment.
    After healing of the fracture, excavating or ostectomy on the bilateral gonial region via intraoral route had little value in correction of this deformity in 2 cases.
    In other 2 cases good results were acquired by extraoral narrowing compression with a simple treatment device before operation or by the action of manual pressure at the time of operation. The P-A cephalogram was useful to evaluate deformity correction and showed about 10mm narrowing without deterioration of occlusion in the case treated with the device.
    In addition, the authors discussed mechanism factors and practical treatment of this deformity.
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  • Jiro ICHIKAWA, Yohichi KURACHI, Shinya ITO, Kazuyuki OTSUKA, Masao NAG ...
    1985 Volume 31 Issue 1 Pages 29-35
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Lipoma may occur anywhere adipose tissue exists, but is rarely found in the oral region. In this region, the buccal mucosa, tongue and oral fundus are often found to be affected.
    We recently experienced three cases of lipoma arising in the alveolar gingival region of a 58 year-old female, a 60 year-old male and a 61 year-old male. The clinical courses are described in this paper.
    The tumors in these cases were excised under local anesthesia. From histological examination, the diagnoses of lipoma were made based on the fact that the circumscribed mass of mature fat cells were observed below thin fibrous connective tissue. These lipomas were each found to be supported by a connective tissue stroma with blood vessels. The prognosis of the three cases are favorable with no sign of relapse.
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  • Yasunori TOTSUKA, Takanori MIZUKOSHI, Hiroyuki NAKAMURA, Mitsugu KUROD ...
    1985 Volume 31 Issue 1 Pages 36-51
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    A clinical study was made of 69 cases, 50 male and 19 female of squamous cell carcinoma of the lower gum treated at the Oral Surgery Department of Hokkaido University, School of Dentistry between 1970 January and 1983 December.
    Ages at first visit ranged from 29 to 83 years old but about 95% were over 50 years old. The majority had clinically advanced disease. Fifty four had radiologically abnormal findings of alveolar crest or mandible, and 30 had clinically metastasis lymph node at the first diagnosis.
    The three year absolute cure rate for all cases was 54.9%. In the comparison of treatment modality, the cure rate treated by surgery was clearly superior to that by radiation therapy and/or chemotherapy: The cure rate of the former was 75.0% and that of the latter was 21.1%. Post-operative tumor control rate was related to the radiological findings of the mandible. The recurrent rate of patients who had radiologically an irregular lytic destruction of the mandible was 42% and that of patients who exhibited an erosion or change of the alveolar crest or mandible was 15%. These results indicate that wide resection with plenty of safety margin is necessary in lower gum canccr that radiologically had irregular lytic destruction.
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  • Hiromichi AKIZUKI, Hiroshi YOSHIDA, Masahiro HASEGAWA, Takeaki OHSAWA, ...
    1985 Volume 31 Issue 1 Pages 52-56
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    A rare case of congenital epulis with natal tooth in a 6-month-old girl is presented. The lesion was excised under general anesthesia. Histological examination revealed that the tooth had scanty root formation and was directly connected to the soft tissue without periodontal membrane. The epulis consisted of fibrous connective tissue covered by layers of stratified squamous epithelium. According to these findings, it was considered that the epulis was formed by the response to irritation of the natal tooth as a result of the upward transposition of germs.
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  • Fujio WAKE, Takashi FUJIBAYASHI, Toshiaki IWASA, Yuji ICHIKAWA, Tadash ...
    1985 Volume 31 Issue 1 Pages 57-62
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Erythroplakia and leukoplakia are generally accepted precancerous lesions of the oral mucosa. Erythroplakia is defined as bright red velvety plaque which is a persistent asymptomatic lesion in any portion of oral cavity except the lip. Its occurrence cannot be characterized clinically or pathologically as being due to any other condition. Because of the ambiguity of its clinical and histological features, it often generates much confusion with leukoplakia and/or some of the inflammatory conditions due to local infection, or subacute or chronic stomatitis associated with the presence of denture, tuberculosis and fungal infections. But it is reported that erythroplakia is more likely to develop into carcinoma than leukoplakia.
    The present paper describes a case of maxillary carcinoma with widely extended erythroplakia involving hard and soft palatal mucosa. The treatment was surgical resection of maxilla including the area with erythroplakia. The postoperative course was free from complication except for slightly low liver function which improved in two months and without clinical problems. The patient has been alive for two years and five months postoperatively without tumor recurrence, and is currently wearing a prosthesis on the resected maxilla which has effectively improved speech. Furthermore, interesting reults of immunological tests concerning non-specific cell-mediated immunologic function of the patient is also reported.
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  • The process of receiving proper treatments
    Setsuko ITOH, Motomasa SASAKI, Harumi MIZUKI, Shigetaka YANAGISAWA, Ma ...
    1985 Volume 31 Issue 1 Pages 63-68
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Submucous cleft palate is troublesome to diagnose, for it is sometimes difficult to find the anomaly in the oral region. There are also many problems in starting its treatment. Therefore, in order to prevent or resolve such problems, we sent questionaires to these patients.
    The resulting conclusions follow:
    1. Most patients visited pediatrics first and secondly obstetrics, home doctors and public health centers, but these medical institutions did not always give correct diagnosis and rarely gave suitable advice. Such suitable advice came mostly from the speech clinic, oral surgery and otolaryngology (79%), followed by pediatric department (10.5%) and others (0%).
    2. We could find that different lapsed time from the first visit by the patients to the clinic till their receiving proper treatments depended upon whether they received good advice or not. In Group A which could get some advice, all cases except one case (cardiac disease) received proper treatment within two years. However, only 22% of Group B and 33% of Group C which could not get proper advice received the treatment within two years. It took 10 years that all remaining cases of both groups received the treatment.
    3. From the above, we considered that the difficulty of diagnosis of submucous cleft palate was due to the lack of suitable clinical systems.
    4. Therefore, we would like to stress the necessity for cooperation between these clinics treating submucous cleft palate.
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  • Yasuo KUMAZAWA, Shigeru TOMITA, Yoshiyuki OHNUMA, Sadamitu FUKUI, Nobo ...
    1985 Volume 31 Issue 1 Pages 69-75
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    This paper reports three cases of familial partial anodontia. These were found through the visit of a 9-year-old girl to our clinic who complained of the absence of the first molars in the maxilla and mandible. A similar absence of teeth was later found in her mother and sister. All these cases showed absence of right and left first molars in the maxilla and mandible, which are the least subject to teeth number anomalies. Familial occurrence, in addition, rendered these cases rare.
    Case 1. A 9-year-old girl.
    Diagnosis: partial anodontia
    765/567//76/67 absent
    Case 2. A 34-year-old woman (mother of Case 1).
    Diagnosis: partial anodontia
    765/567//76/1/1567 absent
    Case 3. A 6-year-old girl (younger sister of Case 1). Diagnosis: partial anodontia
    7652/567/76/1/67 absent
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  • Seishi KAWANO, Takatoshi ITOH, Tohru YAMAUCHI, Sanehiko YOGI, Hiroyuki ...
    1985 Volume 31 Issue 1 Pages 76-80
    Published: January 20, 1985
    Released on J-STAGE: September 13, 2011
    JOURNAL FREE ACCESS
    We reported a case of branchiogenic cyst occurred on the right side of submandibular region.
    Patient was a 47 year-old female in whom the cyst developed on the upper side of the submandibular region. She visited our office because of painless swelling of the right side of the submandibular region on April 4, 1979.
    A diagnosis of tumor of submandibular salivary gland was made and the tumor was excised.
    From histopathological findings that the inner wall was covered with cuboidal epithelium and lymphoid tissue was observed in the lower layer of the epithelium, a definitive diagnosis of branchiogenic cyst was made.
    By scanning electron microscope, many microvilli were observed on the epithelial cell surface.
    The clinical findings, histopathological findings and scanning electron microscopic findings of this case were reported and the literature was reviewed.
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  • Toru SHIGENO, Akio MIZUNO, Toshihide NAKAMURA, Katsutoshi MOTEGI, Hiro ...
    1985 Volume 31 Issue 1 Pages 81-87
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Two rare cases of tuberculosis in the oral and maxillofacial regions are presented. In case 1, a 50-year-old woman, submaxillary lymph node and submaxillary salivary gland were involved. Histopathologic examination of the enucleated materials disclosed central caseous necrosis with Langhans' giant cells in the lymph node and granulomatous changes accompanied with miliary epithelioid tubercle in the salivary gland. In case 2, a 24-year-old woman, the so-called “maxillary lymph node” in the buccal region was affected and histopathologic examination of the enucleated material disclosed extensive caseous necrosis accompaniedwith Langhans' giant cells in the great part of the lymph node. Histopathologic diagnosis of both cases was tuberculosis, though no tubercle bacillus was observed on the Ziel-Neelsen stained sections. The chest X-ray film of patient 1 showed old pulmonary tuberculosis and the chest X-ray film of the other revealed nothing particular. Tuberculin reaction was positive in both patients.
    Both patients underwent chemotherapy after surgical treatment and posttherapeutic course was satisfactory.
    In addition, we reviewed the tuberculosis cases reported in the Japanese literature of oral and maxillofacial surgery for the last ten years. No cases of tuberculosis of the so-called “maxillary lymph node” and the salivary gland were foundout.
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  • Hiroshi HIRANO, Yasuharu TAKENOSHITA, Masuichiro OKA, Hideo TASHIRO
    1985 Volume 31 Issue 1 Pages 88-95
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Orthopantomograms are useful when abnomalities of the jaws, maxillary sinuses and teeth are present.
    In spite of its unsharpness in imaging comparing with routine radiography, orthopantomogram has a special advantage in displaying cases of temporomandibular joint ankylosis because of no need to open the mouth.
    Correct interpretation and evaluation of the range and characteristics of ankylosis are important in treatment planning and surgery. However, only a few reports are found in respect to the orthopantomographic evaluation of temporomandibular joint ankylosis. Thirty-four cases from 1968 to 1982 were observed by this orthopantomographic method.
    As a result, it showed that there is a clear correlation between the extent, degree of fusing and the length in disease of ankylosis. But there are no differences in etiologic factors nor in both sexes. The larger the extent of ankylosis, the larger was the severity of inability on the mouth opening and development hypertrophy of muscular process and antegonial notching was clearly observed.
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  • Manabu MIHARA, Masahiko FUKAYA, Yoshiki TAKAI, Hiroshi INAMOTO, Kazuhi ...
    1985 Volume 31 Issue 1 Pages 96-103
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    There have been many patients suffering from psychomatic diseases in all clinicsin recent years.
    In twenty patients with a psychomatic disease in the oral region (glossodynia, unidentified pain, halitosis and ptyalism), clinical studies on brief psychotherapy. Pharmacotherapy and autogenic training were performed.
    Sixteen cases were female and five of them had anamnesis of myomotomy. The ages of patients ranged from 16 to 87 years old and the average age was 50.
    Twelve patients were seized with anxiety of malignant neoplasms. Vomiting reflex wasseen in only six cases.
    Nineteen patients showed reduction of their symptoms and nine of them were completely healed by our treatment. Suvey results of mental tests exhibited nearly the same trend as clinical results.
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  • Ultrastructure and electron microprobe EDX analysis
    Hidetoshi WAKAE, Shigeru HASHIMOTO, Satoshi HONDA, Takuya KAMOGAWA, Ma ...
    1985 Volume 31 Issue 1 Pages 104-109
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    A case of lipoma which had developed in the 45 ulobuccal transitional portion of a 90-year-old man was reported. In addition to clinical findings, optical and electron microscopic observations, an EDX qualitative spot analysis was applied to the tumor.
    Optical microscopy: The tumor was covered with fibrous connective tissues and internally characterized by a complete increase in mature lipoma.
    Scanning electron microscopy; global lipocytes showed a stone-wall structure, and these cells were enclosed by ivy-like collagen fibers.
    Transmission electron microscopy: Tumor cells showed a membranate structure and the development of organelles in cells was heardly observed.
    EDX qualitative spot analysis: In an analysis of tumor cell membrane, the main constituent elements of the tumor were Cl, S, Ca, P and Mg, and in the liposome, the main constituent elements of the tumor were Si, Cl, S and Ca.
    For one year after the operation, these has been no recurrence of the lesion.
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  • Clinical and Bacteriological Studies of 13 cases
    Youichi NAKAGAWA, Kouichi ASADA, Yasuyoshi Doi, Masato OCHIAI, Taiji M ...
    1985 Volume 31 Issue 1 Pages 110-115
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Thirteen cases of actinomycosis in oral and maxillofacial regions were reported. They were histologically diagnosed by detecting sulfur granules in pus and granulomatous tissue. Clinical, bacteriological and histological studies of these cases revealed the following:
    1. Clinically, five types were recognized: non-abscess indurative type, subcutaneous abscess type, deep abscess type, mandibular ostitis type and secondary infection of cyst type. Subcutaneous abscess type showed the most typical clinical symptoms of actinomycosis.
    2. Histologically, sulfur granules were detected in all the cases, and typical sulfur granules with club formation were seen in 4 cases. In other cases, club formations were not so clear, and their central mass of granules were variable, i. e., a loosely-tangled mass of filaments, a compact mass of filaments or a mixture of them.
    3. Bacteriologically, Actinomyces were detected in 4 cases, and Bacteroides and Streptococcus were dominant in isolated strains from pus.
    4. Treatments of these cases consisted of administration of antibiotics combined with incision, drainage and elimination of predisposing pathologic condition. Penicillins and cephems were mainly administered in duration of 3 days to 3 months. In the non-abscess induration type, the longest term of treatment was needed, although the treatment proved effective eventually.
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  • Masahiko ISOGAI, Kazuhisa FUJIMOTO, Akihide KAMEGAI, Kouichi NAITOH, T ...
    1985 Volume 31 Issue 1 Pages 116-125
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    The outpatients division of the department of Gifu College of Dentistry was opened in April, 1971 and the inpatients division was established in August, 1976. The total number of inpatients was 1, 318 and that of outpatients was 15, 477 till December 31, 1983.
    Clinical and statistical observation of inpatients for the past 7 years was analysed. The number of inpatients increased year by year until 1981.
    The distribution of deseascs of the inpatients is as follows of. Inflammatory disorders (436 cases; 32.5%), cysts (285 cases; 21.3%), traumata (170 cases; 12.7%), extractions (126 cases; 9.4%), tumors (124 cases; 9.3%), facial malformations and jaw deformities (58 cases; 4.3%), salivary gland disorders (20 cases; 1.5%), neural disease (7 cases; 0.5%) and others (22 cases; I.6%).
    It is concluded that numbers of inflammatory and cystic diseases accounted for a high percentage of the total numher of inpatients.
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  • Yoshiki TAKAI, Masahiko FUKAYA, Kazuhisa NAKAYAMA, Kazuhiko SAKAKIBARA ...
    1985 Volume 31 Issue 1 Pages 126-136
    Published: January 20, 1985
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Clinical evaluation of aspoxicillin (ASPC, TA-058) in various infections in the fi eld of oral surgery were carried out.
    Aspoxicillin was administered to 68 patients with various infections. Aspoxicillin was administered by intravenous injection or intramuscular injection at a daily dose of 2g (1g×2 times).
    The following results were obtained:
    Cases consisted of 40 with maxillary ostitis, 9 phlegmon of the floor of the mouth, 9 pencoronitis, 4 odontogenic maxillary sinuitis, 1 post operative maxillary cyst, 3 buccal abscess, 1 peritonsillitis and 1 gingival abscess. The evaluation was made with 68 cases.
    The clinical effects obtained in subjective judgement were excellent in 34 cases, good in29, fair in 2 and poor in 3. The clinical effects obtained in judgement by point were classified as excellent in 33 cases, good in 31 and poor in 4.
    Effective rate in subjective judgement was 92.7%. Effective rate in judgement by point was 94.1%.
    This medicine turned out effective in intravenous as well as intramuscular injections.
    Side effect in one case was facial edematous sensation.
    The elevation of s-GOT, s-GPT was observed after aspoxicillin administration in 4 cases in the laboratory examinations.
    The results indicated the usefulness of aspoxicillin in the treatment of various infections in the field of oral surgery.
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