Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Volume 34, Issue 9
Displaying 1-33 of 33 articles from this issue
  • Masashi YOSHIDA
    1988 Volume 34 Issue 9 Pages 1825-1838
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Changes in immunological response to a living body with malignant tumor have a tendency to complicate infection clinically, and constitute a serious problem. Inflammatory reaction, in which neutrophils emigrate first into the acute inflammation region, is thought to reflect on the immunological response.
    On the other hand, prostaglandins (PGs) are synthesized in many organs, and they have various biological and pharmacological effects. Leukotriene B4 (LTB4), one of the PG related bioregulators, has chemotaxis for neutrophils, which release LTB4 in response to various stimuli.
    Recently, LTB4 released from neutrophils and neutrophil emigration became possible of detection by means of stimulation by Ca-Ionophore A 23187 and skin window test, respectively.
    In the present study, changes in the neutrophil function in rabbit having VX2 carcinoma was investigated with these two methods. The results obtained were as follows.
    1) Two weeks after VX 2 carcinoma transplantation in rabbit tongue, the tumor infiltrated throughout the tongue with necrosis and metastases in cervical lymph nodes and lungs were recognized. At three weeks, rabbits began to feed very little and lose weight rapidly.
    2) The neutrophil number increased 2.5 times three weeks after transplantation.
    3) The concentration of calcium in blood of rabbits with cancer decreased significantly at two weeks against controls (p<0.05).
    4) LTB4, which was separated by stimulating with A 23184 the neutrophiles that had been taken from VX 2 carcinoma rabbits, increased and reached the maximum two weeks after transplantation, which was statistically significant (p<0.001).
    5) The neutrophil emigration by means of skin window test improved markedly three weeks after transplantation.
    6) These findings suggested that LTB4 release from neutrophils varied with the growth of VX2 carcinoma and became an immunologial parameter.
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  • Kouichi MATSUMOTO, Hakuro OKANO, Kazuhiro MATSUMOTO, Yuichi MURATA, Ri ...
    1988 Volume 34 Issue 9 Pages 1839-1844
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    A palatal abscess content was examined bacteriologically following both aerobic and anaerobic transport. Bacterial growth was not recognized after aerobic transport. while anaerobic incubation immediately after anaerobic transport resulted in a positive culture. All isolates were anaerobes, such as Bacteroides ruminicola ss. ruminicola, Fusobacterium russii, Eubacterium lentum, and Peptostreptococcus anaerobius.
    The anaerobes did not survive a 120 minute-exposure to air. These results indicate that a continuous anaerobic system is necessary to gain information about causative agents in oral infections.
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  • Katsuya SAKAMOTO, Juntaro NISHIO, Mikihiko KOGOU, Yasushi HAMAMURA, Ka ...
    1988 Volume 34 Issue 9 Pages 1845-1851
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    This study was intended to clarify the mechanical contraction properties of the tensor veli palatini muscle in dogs. Twenty adult dogs were used under an intraperitoneum anesthesia of the pentobarbital sodium. The tension of the tensor veli paltini muscle was recorded by electrical stimulation to the motor nerve.
    Results were as follows:
    1. The contraction time and half relaxation time of maximal isometric twitch of the muscle were calculated as 13.7±0.7 msec and 10.4±1.2 msec, respectively.
    2. A clear summation of muscle contractions was obtained with stimulation at 20 Hz and maximal tetanic tension was at 90 Hz. The tetanus twitch tension ratio wasfound to be 10.7±1.1.
    3. The maximum rate of tension rise was observed at 150 Hz and value was 2.5±0.5 times as long as the rate of a twitch contraction.
    4. The contraction rate of an isotonic twitch was 3.2±0.7% and the maximum contraction rate was obtained at 80 Hz which was 26.3±1.9%.
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  • Atsushi SATO, Masayasu IWASE, Yukari GOGUN, Akiyuki NISHIMURA, Shigeyo ...
    1988 Volume 34 Issue 9 Pages 1852-1856
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Bleomycin (BLM) has been frequently used for the treatment of oral cancer. BLM is thought to produce active oxygen species such as superoxide anion, which have been shown to bring on tissue damage. It is therefore suggested that active oxygen species may have an antitumor effect. This study was undertaken to clarify the effect of BLM on active oxygen species generation in human peripheral blood neutrophils.
    For this purpose, peripheral blood neutrophils were obtained from normal volunteers and then luminol dependent chemiluminescence (LDCL) was measured to estimate the generation of active oxygen species. Phorbol myristate acetate (PMA), N-formyl-methionyl-leucyl-phenylalanine (FMLP) or serum opsonized zymosan (OPZ) was used as stimulants of LDCL generation.
    As a result, at concentrations over 5 μg/ml BLM, LDCL without those stimulants was slightly increased. LDCL stimulated by PMA or FMLP is obviously increased by the addition of O.1 μg/ml BLM or 0.01 μg/ml, respectively. While LDCL induced by OPZ was not increased by BLM. 5-fluorouracil (5-Fu) an antitumor agent, had also no effect on LDCL generation.
    These results suggest that BLM may promote or enhance the generation of active oxygen species in human neutrophils. Through this function, BLM may exhibit an antitumor activity.
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  • YOZO YAMADA
    1988 Volume 34 Issue 9 Pages 1857-1873
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    High-power Nd-YAG laser (Power density: 1910 W/cm2, Total energy: 1188 J) was irradiated to canine mandibles, and bone defects reaching to bone marrow were made. The author compared the difference of healing process and histological changes in time course between the no treatment group, the group with removed carbonized layer, and the control group in which defects were made by bone bur instead of laser irradiation. The comparative studies were performed by means of soft X-ray radiographic, histopathological method, microradiography and OTC labelling method. The results obtained were as follows.
    (1) The marginal region of Nd-YAG laser wound showed minor cracks where calcification progressed day by day and the change was clealy observed as a radiopaque image and fluorescent image. No remarkable change was observed even after 24 weeks. Also, necrosis of osteocyteand vacuolation were observed in a wider range, while similar findings were observed although narrow in width in the group with removed carbonized layer. However, the control would showed no such finding.
    (2) Defective group by bone bur showed the formation of new bone after 2 weeks and healing process of bone was nearly completed after 20 weeks. In the group with removed carbonized layer after Nd-YAG laser irradiation, new bone were formed in bone marrow after 4 weeks, and in marginal part after 8 weeks and defects were filled after 20 weeks. In non-treated group after Nd-YAG laser irradiation, new bone was formed in bone marrow after 4 weeks, in marginal region after 16 weeks. However, carbonized and degenerated necrosis layers remained even after 24 weeks and defective cavities still existed. Finally, the bottoms of the cavities were lined with new bone from the bone marrow. The change seemed to be a compensatory reaction against delayed closure at the punctured site in cortex.
    These results indicated that Nd-YAG laser irradiation gives disorder of osseous tissue in wide range and the healing process was delayed. However, removal of carbonized layer seemed to make it possible that laser irradiated wounds had almost the same healing process as bone bur wounds.
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  • Isao MIZUNO, Noriaki SABURI, Nozomu TAGUCHI, Toshio KANEDA, Takeshi HO ...
    1988 Volume 34 Issue 9 Pages 1874-1880
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Three week-old and 6 week-old rats were given intraperitoneal injections of colchicine in a 0.05 percent saline solution, the dosage was 1 mg/kg body-weight. Accumulation of arrested metaphases in the fibrous zone of the mandibular condyle could be observed. Light microscope study of the plastic-embedded semithin sections of mandibular condyle identified two layers (F1 layer and F2 layer) in the fibrous zone. In these two layers age related changes of the tissue structure were obserbed.
    It is shown that the fibroblast-like cells in F1 and F2 layers have mitotic division ability as old as 6 weeks of age, and that the F1 layer tended to disapper before 6 weeks, while the F2 layer became thicker because of a conspicuous formation of thick bundles of collagen fibers in the matrix.
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  • Comparative observation with iliac bone and kiel bone transplantation (1)
    Katsuyuki TERABE, Hiroshige CHIBA, Noboru SONOYAMA
    1988 Volume 34 Issue 9 Pages 1881-1899
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    To study structural changes which occur following bone transplantation along with internal remodelling of a transplanted bone, its surrounding alveolar bone and thejaw bone in the remote area, autogenous iliac bone and kiel bone were transplanted into theleft and right lower jaw, respectively, of adult dogs. Time tracing was performed by using three labelling agents (tetracycline, calcein, alizarin complexone) during the experiment (6 to 184 days after bone transplantation). Angiography was also conducted prior to the animals' sacrifice. Microradiograms, labelling findings and angiograms obtained from large ground sections prepared from the lower jaw were compared. The following results were obtained.
    In both the left and right transplantation beds, capillary blood vessels newly developed at the transplantation site showed d network-like proliferation and developed in the transplanted bone prior to new bone formation around the transplanted bone. Almost simultaneously with this change, absorption of the existing bone and new bone formation became active in the interior of the alveolar bone around the transplantation bed.
    The new bone in the transplantation beds showed compact proliferation 10 days and 30 days after transplantation of the iliac bone and the kiel bone, respectively. The degree of calcification became almost the same as that for the surrounding alveolar bone 60 days and 120days, respectively, after transplantation.
    With the new bone formation in the transplantation bed that received the kiel bone, addition of bone proceeded actively around the bed, in the interior of the alveolar bone on the surface layer of the remote region and in the compact bone facing the mandibular canal in the lower margin (lining phenomenon).
    The patterns of new bone formation in the bed that received the iliac bone included a new bone proliferation from the base toward the apex of the transplantation bed inone case, and gradual replacement of the transplanted bone by new bone originating in the surrounding area of the transplanted bone in another case. By contrast, the kiel bone was replaced almostentirely by new bone developing around the transplanted bone. The iliac bone and kid bone were absorbed and had disappeared by about 30 days and 140 days, respectively, after transplantation.
    These changes in the kiel bone transplantation group were observed later than those in the iliac bone transplantation group. The process of their appearance was influenced by individual differences, age, transplantation material, etc.
    Absorption of new bone in the transplantation bed began about 60 days after transplantation, and it continued even up to 184 days after transplantation. Therefore on the side that received the iliac bone, the site around the apex of the transplantation bed and its vicinity became compact, while the base became porous. On the side that received the kiel bone, bone absorption and addition were repeated, with the result that the base of the transplantation bed was occupied by bone trabeculae which were highly calcified.
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  • Comparative observation with iliac bone and kiel bone transplantation (2)
    Katsuyuki TERABE, Hiroshige CHIBA, Noboru SONOYAMA
    1988 Volume 34 Issue 9 Pages 1900-1914
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
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  • Tetsuo SHIMOYAMA, Toshifumi OZAWA, Naoki SUGAWA, Norio HORIE, Hideo HO ...
    1988 Volume 34 Issue 9 Pages 1915-1920
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Two cases of nasopalatine duct cyst were investigated clinically and histopathologically. The patients were 47 and 29 year-old females. Inflammatory symptoms were seen in the labial gingiva of the upper front teeth and the middle part of the palate. In X-ray findings, there was a pear-shaped or heart-shaped X-ray image the size of the tip of the little finger in the area corresponding to the incisive canal. In the operative findings, there was a cyst in the incisive canal in each case, and adhesion between the cystic wall and the nasopalatine nerve. There was no relation between the cysts and the apexes of the central incisors. In the histopathological findings, the cystic wall consisted of stratified epithelium in both cases, and there was also some ciliated pseudostratified epithelium in one case. There was subcutaneous infiltration of inflammatory cells, as well as nerve tissue in one case and a vessel in one case.
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  • Keigo KUDO, Kiyoshi SEGAWA, Yoshiyasu FUKUTA, Masaru SHOJI, Hidenori T ...
    1988 Volume 34 Issue 9 Pages 1921-1924
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    A combination therapy was carried out that used antitumor agents with or without irradiation and surgery for 30 squamous cell carcinomas of the lower alveolus and gingiva during 1975-4986. Therapeutic results of a 5-year accumulative survival rate was 71.8% of all 30 patients: 75% in 10 early stages and 70% in 20 advanced ones. In mandible surgery, 83% of 13 marginal resections and 75% of 12 segmental and hemiresections were superior than in 30% of 5 patients without surgery. In 9 patients that died, 5 distant metastasis (55.6%) showed a higher survival rate than 3 primary tumors (33.1%) and 1 regional lymph node metastasis (11.1%).
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  • Akira SUZUKI, Masataka HORII, Takahiro KAWAKAMI, Yasuo KINOSHITA, Kazu ...
    1988 Volume 34 Issue 9 Pages 1925-1929
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    We examined a case of lateral cervical cyst in the right lateral cervical region of a 39-year-old male. The cyst was surgically removed under general anesthesia.
    According to Bailey's classification, this case was considered to be Type II Histopathologically, the inner wall of the cyst was covered by the squamous epithelium, and the lymphatic tissue was observed below the epithelium. Biochemically, the cyst content showed high activities of γ-GPT, GOT, LDH, and amylase. In this case it was considered that the cells from salivary glands were secreting high amylase in the cyst wall.
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  • Yasunori MURAMATSU, Akihide KAMEGAI, Syunsuke KUMASA, Noriyasu MURASE, ...
    1988 Volume 34 Issue 9 Pages 1930-1940
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Cleidocranial dysplasia is characterized by abnormal ossification, especially in clavices and skull, oral and dental anomalies, together with hereditary characteristics.
    Martin first reported this disease in 1765, and since then more than 600 cases were reported abroad, and more than 100 cases in Japan.
    A 27-year-old man consulted us with complaints of oppressive pain, bleeding and mandibular fracture. The prognosis was fairly good after surgical treatment.
    Based on retrospective survey of 241 cases of cleidocranial dysplasia reported in Japanese literatures from 1918 to the 1986, the results are summarized as follows:
    1) 82.2% were abnormalities of the clavicles.
    2) 83.8% were disturbances of skull ossification.
    3) 58.1% were oral and dental anomalies.
    4) 23.7% were hereditary characteristics.
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  • Masaru HIROTANI, Suguru HAMADA, Masaaki SUGIHARA, Takashi UCHIHASHI, T ...
    1988 Volume 34 Issue 9 Pages 1941-1948
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    We have studied clinicostatistically 462 in-patients from 1979 to 1986 at the Department of Oral & Maxillofacial Surgery, Kinki University Faculty of Medicine.
    From this study, we obtained the following conclusions:
    1) Of 462 in-patients, 293 were male and 169 were female (1.7:1).
    2) The following four diseases accounted for 84.7%: Injuries were 25.8% (119 cases), tumors 21.4% (99 cases involving 59 maligmant tumors) cysts 19.5% (90 cases) and inflammatory diseases 18.0% (83 cases).
    3) The number of operations were 371 which involved 92 Injuries, 84 cysts, 77 tumors and 37 Inflammatory diseases.
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  • Hiroshi INAMOTO, Masahiko FUKAYA, Mikiko HIRAMATSU, Kenji YOSHIDA, Yas ...
    1988 Volume 34 Issue 9 Pages 1949-1956
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    This is a study of postoperative changes in the mandibular prognathism surgically corrected by sagittal split osteotomy (Obwegeser-Dal Pont method), using cephalometric analysis of 10 cases of long-term prognosis (comparing cases of 1 year with those of more than 10 years).
    All cases had good occlusion and none had poor anterior occlusion due to some degree of relapse. The mean values of movement of 10 of the mandibular structure on lateral cephalograms 10 years after the operation tended to move slightly downwards and backwards. The axial inclination of the upper incisors tended to lean toward lingual, and that of the lower incisor tended to lean toward labial. 5 cases had a little back-ward movement of pog, 3 cases had a forward movement, and 2 cases had no movement. The greatest changes were observed in 2 cases with a 3.5mm relapse on pog, but maintained good occlusion. The axial inclinations of the incisors were quite varied but were not due to the movement of the mandibular structure. From this study, we concluded that sagittal split osteotomy (Obwegeser-Dal Pont method) was an excellent type of operation resulting in maintenance of good stability of mandibular structure and occlusion even after a long time (more than 10 years after the operation).
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  • Especially behaviors of the involved teeth
    Kazuhiro TOMINAGA, Toshihiro KIKUTA, Jin-ichi FUKUDA, Shunsuke UEMURA, ...
    1988 Volume 34 Issue 9 Pages 1957-1962
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Marsupialization is one of the best therapies for dentigerous cyst, especially for the possibility of preservation of the involved permanent tooth. Many factors, for example, the age of the patient, the region of the cyst and the situation of the involved tooth itself, had made it difficult to ensure the prognosis of the displaced teeth on their spontaneous eruption following the surgery. Fifteen dentigerous cysts in the lower premolar region in twelve children aged eight to thirteen were marsupialized, and the inclination of adjacent teeth was prevented by using an acrylic denture type obturator. We observed the reactions of the involved teeth and the decrease in size of the cysts. The results were as follows;
    1. In the nine central dentigerous cysts which surround the entire crown of the involved teeth, all of the teeth, even horizontal tilted teeth or matured teeth, erupted in almost normal positions with marsupialization and retention of the eruption spaces.
    2. In the six lateral dentigerous cysts which form at one side of the involved teeth, the teeth didn't have enough capacities to improve their tilted dental axes with marsupialization. Especially on the cases involving matured teeth, they couldn't erupt enough without orthodontic intervention.
    3. The bony regeneration was comparatively rapidly achieved with marsupialization. Every cyst remained only a small cavity in 3 to 6 months after surgery. The cavity also disappeared about one or one and half years later when the involved tooth completed eruption
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  • Noriaki AOKI, Ken ITO, Satoru UMINO, Yoshimi ISHIKAWA, SUSUMU OHMURA, ...
    1988 Volume 34 Issue 9 Pages 1963-1969
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Warthin's tumor is a relatively rare epithelial benign tumor of the salivary gland.
    Recently, we experienced a case of multiple Warthin's tumor in the bilateral parotid glands. A 56-year-old man visited a surgeon and underwent the operation for Warthin's tumor of the left parotid gland in 1975. In 1984 he noticed a painless mass in the left parotid gland and visited Yokohama City University Hospital. We performed left superficial parotidectomy and enucleated the mass of the deep lobe.
    There were two removed tumors both measuring 20 × 20mm and located in the superficial lobe and in the deep lobe respectively. The cut surface of the tumors was solid and yellowish white. A consequent histopathologic diagnosis was Warthin's tumor.
    In 1987 we noticed a painless mass below the right parotid gland. The clinical diagnosis was Warthin's tumor and we performed a right superficial parotidectomy.
    There removed were three tumors, two were 15.0 × 15.0mm in size respectively and the third was 7.0 × 7.0mm. The cut surface of these tumors was solid and yellowish white. The former (two tumors) were histopathologically diagnosed as Warthin's tumor and the latter tumor was done as normal lymph node.
    About 150 Warthin's tumors cases were reported in Japan between 1982 to 1987. Among them, 11 cases (7.3%) showed bilateral manifestication. No recurrence was noticed about 10 months after the operation, but we believe it is necessary to observe his postoperative course very carefully.
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  • Tohru SAITO, Hiroshi FUKUDA, Makoto ARISUE, Akemi MATSUDA, Akihito KUR ...
    1988 Volume 34 Issue 9 Pages 1970-1975
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    55 patients, who had xerostomia or autoimmune diseases such as RA or SLE and were suspected as Sjögren's syndrome (Sjs) based on a sialogram of the parotis, were evaluated in order to clarify the relationship of the sialographical findings to the clinical and the histopathological findings of the salivary glands. The patients were classified into three groups according to Fukuda's sialographical classification for Sjs (Class I-Class IV). 32 patients were classified as Class II, which suggests an early stage of Sjs. 15 and 8 patients were classified into Class III and Class IV, which suggest advanced stages of Sjs, respectively. 46% of the patients classified as Class II, 77% of Class III and 67% of Class IV were diagnosed as keratoconjunctivitis sicca (KCS), and a high incidence of KCS was observed in the patients of each class. 44%, 67% and 13% of the patients classified as Class II, Class III and Class IV had another autoimmune disease. The amount of the salivary flow from the parotid gland in the patients classified as Class II, Class III and Class IV, stimulated by 10% citric acid, were 3.4 ± 1.5 ml/5 min, 2.8 ± 1.4 ml/5 min and 2.7 ± 1.7 ml/5 ml, respectively. The amount of the salivary flow in each class was lower than that of the normal healthy individuals (4.5 ± 1.5 ml/5 min), and as the sialographical classification advanced, a decreased salivary flow was noted. 22%, 87% and 88% of the patients, diagnosed as Class II, Class III and Class IV were indicated Sjs by a histopathological examination of the parotid and/or labial glands.
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  • Takashi MIMA, Masahiro URADE, Takahumi OGURA, Takuya KURIMOTO, Masaya ...
    1988 Volume 34 Issue 9 Pages 1976-1981
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    A rare case of tongue carcinoma (T3N1M0) with multiple metastases was reported. In this case, multiple metastases to the upper lip, gingiva of the upper left canine region and subcutaneous tissue in the trunk and extremities were found 7 months after the initial treatment of tumor excision. Local tumor recurrence was not observed during the follow-up period, and metastasis to the lung was not suspected until the late stage.
    Three tumor cell lines were established from the metastatic sites of the right anterior thoracic wall, upper lip and right back of the trunk, and were designated as SCCKN-Br, SCCKN-Li and SCCKN-Ba, respectively. These cell lines were tumorigenic in nude mice and produced tumors which were diagnosed histopathologically as moderately differentiated squamous cell carcinoma similar to those of the primary and metastatic sites.
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  • Akitsugu MURAKAMI, Kougi TAKAMAN, Hiroaki MURATA, Shinji KIDA, Kunihir ...
    1988 Volume 34 Issue 9 Pages 1982-1986
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Williams' syndrome is a congenital disease which mainly shows various heart disorders, the unique face and undergrowth of the mind or the body. In addition this disease shows some disorders of the mouth, for example, hyperplasia, abnormal arrangement of the teeth and high palate.
    We experienced a case of mandibular cyst in the patient diagnosed as Williams' syndrome, and describe outline of this case.
    The patient was a 10-year-old male. He visited our hospital with the chief complaint of the swelling of gingiva around 6. At birth he showed the unique face, but the chromosome examination indicated normalcy.
    The general examination revealed short height and the unique so called, elfin face. Oral examination revealed diffuse swelling of buccal gingiva around 6 with no fluctuation, no spontaneous pain or oppsessive pain. Moreover it revealed many caries, abnormal teeth eruption, tooth defects and high palate.
    X-ray findings revealed a discrete radiolucent picture about pigeon egg size around impacted 6 impacted supernumerary teeth and the lack of dental germ.
    The echocardiogram and cardiac catheterization examinations revealed valvular aortic stenosis, but supra-valvular aortic stenosis was not observed.
    Concerning heart disorders, we judged it better to observe the progress. The cyst was extirpated completely under local anesthesia for the purpose of preventing pathologic fracture of the mandible.
    The progress is favorable with no abnormality.
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  • Toru SATO, Akio WATANABE, Kyoju NAKAJIMA, Kouichi ASADA, Katsunori ISH ...
    1988 Volume 34 Issue 9 Pages 1987-1993
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Osteopetrosis is a rare disorder characterized by symmetrical systemic sclerosis of skeletal bone which gives rise to susceptibility to fracture and osteomyelitis. Frequently dentition development is affected. A case of osteopetrosis in a 20-year-old female including various forms of dentition disorders i.e., impaction of 765 678 E3 B3, distorted crowns of 5 5, enamel hypoplasia of 43 3 4 4, arrested root development of 35, curved roots of 3 3, delayed root development of 5 and dentigerous cyst of 3, is described. In family history, the parents were consanguinity and the younger brother died of unknown etiology at one year old. Systemic roentogenological examination revealed characteristic findings e.g., sclerosis of the base of skull, “sandwich” appearance of the spine, “bone within a bone” appearance of the epiphises of long bones. By clinical examinations, anemia and cerebral nerve palsy were not observed. The serum calcium, phosphorus, alkaline phosphatase, thyrocalcitonin and parathormone levels were within normal limits. Impacted E3 B and 3 associated with dentigerous cyst were surgically removed under local anesthesia and intravenous dripping infusion of piperacillin. The wounds healed uneventfully. Microscopically, hyperplastic cementum of the root of 3 showed ankylosis with bone. Sclerosed cancellous bone of the mandible was composed of thickened lamellar bone exhibiting mosaic pattern with cement lines.
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  • Yoshimitsu KAMEYAMA, Yoshihiro SAKAKI, Toyose UCHIDA, Nagayoshi YAMADA
    1988 Volume 34 Issue 9 Pages 1994-1999
    Published: September 20, 1988
    Released on J-STAGE: September 13, 2011
    JOURNAL FREE ACCESS
    A case of neurilemmoma with ulcer on soft palate of a 12 year old boy was reported.
    A statistical observation of 39 cases of this disease reported in written form in the Japanese Journal of Oral Maxillofacial Surgery from Vols. 1 to 33 (6) was also made.
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  • Report of a case
    Tadao SUGIMOTO, Harutaka HIMEDA, Takashi NAKAMURA, Hiroshi IKEDA, Kazu ...
    1988 Volume 34 Issue 9 Pages 2000-2008
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Sialolithiasis, the occurrence of calcureous concretions in the salivary ducts or glands, is most common in middle-aged adults but is rare in childhood.
    We recently experienced a case of sialolithiasis in left Wharton's duct of a 3-year-old boy and reported on it with some comments based on the literature.
    The removed calculus was 4 × 3 × 2 mm whitish yellow, oval in shape, rough surface and 24 mg in weight. The cut surface of the salivary calculus showed a structure made of concentric layers surrounding central cores. SEM findings of the central cores and concentric layers showed rough small grained configurations. The X-ray microanalysis showed that the calculus contained chemical elements such as P, Ca, Mg, Al, Si, K.
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  • Ryoji MIZUKAMI, Kouichi ASADA, Youichi NAKAGAWA, Hideo YAMAMOTO, Katsu ...
    1988 Volume 34 Issue 9 Pages 2009-2011
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Lingual osseous choristoma is a rare lesion of unknown etiology, usually found on the dorsum of the tongue. To date, twelve cases have been reported in the Japanese literature. An additional case of lingual osseous choristoma in a 28-year-old female is described. The lesion appeared as a pedunculated mass, 3×3×5mm, on the region of the vallate papilla. The clinical impression was hypertrophic vallate papilla. The mass was excisedunder general anesthesia. Histologically the lesion consisted of a well-circumscribed lamellar bone surrounded by dense fibrous connective tissue and was diagnosed as lingual osseous choristoma.
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  • Yoshihiko YOKOE, Hisashi ADACHI, Masahiro NOSE, Hideki MATSUI, Masazum ...
    1988 Volume 34 Issue 9 Pages 2012-2017
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    55 patients with squamous cell carcinoma of the lower gum treated in the Department of Oral and Maxillofacial Surgery at Kyoto University Hospital during the past 20 years were followed up and retrospectively studied.
    The patients consisted of 37 males and 18 females, and ages at first visit ranged from 41 to 81 years old. According to the TNM-Classification of the UICC (1978), T1: 2 cases, T2: 10 cases, T3: 6 cases and T4: 37 cases. 9 cases were NO and all others had clinically lymph node metastasis at the first diagnosis.
    The cumulative five years survival rate was 46.9% in all cases, 15 cases treated by combined therapy of surgery, irradiation and chemotherapy were calculated as 67.1%, on the other hand, non-surgical group of 15 cases were calculated as 0%.
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  • Makoto IWAMOTO, Kenji KURASHINA, Syuichiro NEBASHI, Toshikazu MINEMURA ...
    1988 Volume 34 Issue 9 Pages 2018-2021
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    It is generally accepted that erythroplakia is a precancerous lesion of the oral mucosa like leukoplakia. It appears as a bright-red, velvety or slightly granular, asymptomatic plaque and is reported to be more likely to develop into carcinoma than leukoplakia.
    In this paper, a case of early invasive carcinoma of the tongue with an appearance of erythroplakia, is reported. The lesion was resected at the level of muscles and the exposed surface of muscle was irradiated with Nd-YAG LASER system. There has been no evidence of recurrence for the past one year follow up.
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  • Masataka HORII, Yasuo KINOSHITA, Jun KURAUCHI, Yoshio SAITO, Yoshiki T ...
    1988 Volume 34 Issue 9 Pages 2022-2024
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    We examined a case of Chondroid Syringoma of the upper lip region of a 51-year-old male.
    Chondroid Syringoma is rare or mixed tumor of the skin and a benign neoplasm of the sweat glands that appears to be composed of a mixture of epithelial and mesenchymal tissues.
    It is usually located on the skin of the head and neck, with the nose, cheek and upper lip are the commonest sites.
    It occurs frequently in males, M: F ratio being 2. 17: 1. The tumor appears as small, painless, dermal or subcutaneous non-ulcerated, solitary, firm, and may remain unchanged for many years.
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  • Tazuko SATOH, Yasuyuki UCHIKAWA, Yoshihiko TOKIYASU, Kazuya INOSHITA, ...
    1988 Volume 34 Issue 9 Pages 2025-2030
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Nifedipine has been applied clinically to circulatory disorders such as essential hypertension, renal hypertension and angina cordis, but has been rapid in gaining popularity in Japan. Its mechanism of action is as follows:
    This drug works on the cell membrane and obstructs the influx of calcium ions into thecell. This change depresses contractility, dilates the coronary arteries and decreases myocardial oxygen consumption.
    On the other hand, as do all effective drugs, this drug has side effects, one of which is gingival hyperplasia.
    This clinical condition is extremely similar to the gingival hyperplasia induced by dyphenylhydantoin, used for the treatment of epilepsy.
    Patients with nifedipine-induced gingival hypertension often visit the dental clinic without noticing the causal relation to the drug.
    A 60-year-old man visited our hospital with a chief complaint of unpleasant changes in his gingiva over 4 months. He had been receiving nifedipine for his hypertension as prescribed by his physician for about one year.
    In general, once administration of the drug is stopped gingival hyperplasia can be cured only by scaling and maintaining a strict tooth brushing regimen.
    This patient was cured and his gingiva were easily restored to health.
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  • Takahisa YAMADA, Tazuko SATOH, Fumihisa KIKUCHI, Narumi NOMURA, Noboru ...
    1988 Volume 34 Issue 9 Pages 2031-2038
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Oral surgeons sometimes encounter patients with foreign bodies in their jaws which require dental treatment. Occasionally it is difficult to extract them.
    Twenty-eight patients with foreign bodies requiring dental treatment were admitted to our department of Oral and Maxillofacial Surgery over about a 4-year period and may be summaried as follows:
    1. Most patients were in their 20s or 30s, and foreign bodies were less common amongthe elderly. Most upper jaw foreign bodies were in women, while the incidence of foreign bodies in the lower jaw was more common in men.
    2. Most foreign bodies in the maxilla were located in the first molar, and all foreign bodies were in the region of the third molar in the mandible.
    3. More cases occurred on the right side of the maxilla than the left, but there was no difference in lower jaw laterality.
    4. As for type of foreign body, most were the radixis of the tooth in both jaws, a few were filling material of the dental canal, the whole body of the tooth or material from dental implants.
    5. The initial treatment in almost all patients with foreign bodies was no treatment on the upper jaw and antibiotics were given to only 4 patients.
    6. Fifteen, about 70%, patients visited the hospital within 7 days after their accident and the longest interval before treatment was one patient who come to the clinic 6 years after his accident. All patients were operated on within 5 days after their accident when the foreign body was in the lower jaw.
    7. Twelve patients were operated on within 7 days for foreign bodies in the upper jaw and 5 patients within 3 days for foreign bodies in the lower jaw after first seeking consultation.
    8. The surgical technique in most cases of maxillary foreign bodies was enlargement of the wound and extraction of the foreign body, in the lower jaw, an incision was made and soft tissues dissected from the lingual side to exposed and extract the foreign body.
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  • Yoshiya UEYAMA, Tomohiro MATSUMURA, Takuji KIMURA, Hiroshi OHTA, Hirok ...
    1988 Volume 34 Issue 9 Pages 2039-2044
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Verruciform xanthoma is a non-tumorous lesion of unknown etiology and uncertain nature, first described by Shafer in 1971.
    Histologically the characteristic features of the lesion are the presence of rete pegs extremely elongated and large, swollen foam cells or xanthoma cells.
    This paper presented the case of an 80-year-old female with a lesion at the right lateral margin of the tongue. Histochemical and immunohistochemical detections were also made, and the origin of histiocytes as to foam cells were discussed. In addition the reports concerning it in Japan were reviewed.
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  • Kimio UCHIYAMA, Shinobu IKEUCHI, Yutaka SUMII, Toshiaki KURASHIMA, Hid ...
    1988 Volume 34 Issue 9 Pages 2045-2048
    Published: September 20, 1988
    Released on J-STAGE: September 13, 2011
    JOURNAL FREE ACCESS
    In this report, we described the details of a case of adenoid cystic carcinoma of the sublingual gland.
    A 67-year old female was referred to our department with a chief complaint of a pain and swelling at the left floor of the mouth.
    Clinical diagnosis was suspected malignant tumor by CT scan which showed an irregularly margined mass. The patient was treated by neo-adjuvant chemotherapy with CDDP and 5-FU which was not effective, and then left radical neck dissection, wide resection of left floor of the mouth and partial resection of left tongue with partial resection of the mandible and suprahyoid dissection on the right. Histological examination revealed the lesion as adenoid cystic carcinoma.
    She has been observed for 1 year and 5 months without signs of recurrence.
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  • Kimio UCHIYAMA, Tsutomu EBIHARA, Yutaka OKADA, Souichirou ASANAMI, Yas ...
    1988 Volume 34 Issue 9 Pages 2049-2056
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Two cases of basal cell nevus syndrome are reported; the first was an 18 year-old man who visited with a chief complaint of malocclusion. Multiple jaw cysts, mandibular prognathism, a broad nasal root, ocular hypertelorism, calcification of the flax cerebri, bifid-rib and pit of palm were presented.
    In the other case, his sister, a 23 year-old woman, had findings same as her brother. In both cases, jaw cysts were enucleated. Histopathological diagnosis of the jaw cysts were a primordial cyst and a dentigerous cyst.
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  • Immunohistological studies
    Yasuo TAKAYAMA, Toshihiko ISHII, Yosinari TOHYAMA, Mitsuhiko MATSUMOTO ...
    1988 Volume 34 Issue 9 Pages 2057-2063
    Published: September 20, 1988
    Released on J-STAGE: September 13, 2011
    JOURNAL FREE ACCESS
    A case of adenolymphoma occurred in the left parotid gland of a 60-year old male treated with superficial parotidectomy was described.
    The treatment of choice was superficial parotidectomy, but not enucleation of tumor, because of the multicentric development of this tumor, or the risk of facial nerve injury during operative procedures.
    Histopathological examination revealed that epithelial tissue was arranged in two-layers of columnar and cuboidal cells with papillary proliferation, and projected into cystic cavities. Interstitial tissue contained lymphoid tissue with several germinal centers.
    Immunohistological studies on IgG, IgA, IgM, secretory component (SC), T and B cells were performed and following results were obtained. In the lymphoid tissue, the majority of lymphocytes were B cell and a few T cells were observed beneath the epithelium. The number of IgG-positive cells made it the most predominant isotype in the lymphoid tissue followed by IgA-, and IgM-positive cells. Localization of IgA and SC were observed in some parts of columnar and cuboidal cells of the epithelium as well as in the contents of cystic cavities suggesting the presence of SC-mediated transport mechanism of IgA in adenolymphoma.
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  • 6. Lower gum cancer
    Akira ARASAKI, Masahiro YAMASIRO, Hajime SUNAKAWA, Osamu TOMISIMA, Hid ...
    1988 Volume 34 Issue 9 Pages 2064-2070
    Published: September 20, 1988
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    We conducted a clinico-pathological analysis on 26 primary cases of lower gum cancer at the clinic of the Oral Surgery Department of Ryukyus University Hospital. The results of the present study were as follows:
    1)M can age of the series was 65.8 years. Of 26 lower gum cancers, 18 cases were male and 8 were female.
    2) Cases treated by irradiation (R) were 15, treated by irradiation and surgery (R+S) were 11.
    3) Clinically, T 4 cases and Stage 4 cases were most frequently encountered. The survival rate of high stage cases and advanced cases were lower than those of low stage ones and those of non-advanced ones. Radiologically, endophytic type (invasive type or deep erosive type) was related to poor prognosis.
    4) Histologically, there were 9 cases (34.6%) of well differentiated type and 15 cases (57.7%) of moderately differentiated type. Cases of well differentiated type had good prognosis. Regarding the mode of cancer invasion, cases of type 3 (no distinct borderline) were most frequently encountered. Cases of type 3 (no distinct borderline) and type 4 D (diffuse invasion) had poor prognosis.
    5) The 5 year cumulative survival rate in each therapy was 32.0%(R), 81.8%(R-FS), and the overall 5 year survival rate was 55.7%.
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