Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Volume 53, Issue 8
Displaying 1-12 of 12 articles from this issue
  • Yukiko ONO, Naoya IZUMI, Michiko YOSHIZAWA, Chikara SAITO
    2007 Volume 53 Issue 8 Pages 468-480
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Recently, some types of cell/biomaterial composites have been fabricated to regenerate bone experimentallyand clinically. The objectives of this study were to compare the osteogenic potential of bone marrow cellsdifferentiated into osteoblast-like cell/beta-TCP composites with that of undifferentiated bone marrow cell/beta-TCP composites implanted at ectopic sites, to investigate how such bone marrow cells and osteoclasts histologicallyparticipate in the absorption of beta-TCP and bone formation, and to assess the potential use of these compositesas an alternative material for the repair of jaw bone defects.
    Fischer rat bone marrow cells were cultured and divided into two different medium groups. One medium containedstandard medium plus beta-glycerophosphate, dexamethasone and ascorbic acid to induce osteoblast likecells. The other medium did not contain the additives. Porous beta-TCP blocks (OSferion (R)) were seeded withthe cells in each group; the former was designated as the differentiated group and the latter as the undifferentiatedgroup. As a negative control, beta TCP blocks without cell seeding were used. The blocks were implanted subcutaneouslyand harvested 6 weeks and 12 weeks after implantation for histological analysis.
    In the differentiated group, bone extensively covered the surfaces of the pores of the beta-TCP block, andosteoblasts lined the new bone. Osteoclasts were observed on the surfaces of the pores. Twelve weeks afterimplantation, the new bone was thicker than that observed at 6 weeks, and the cement lines were also observed.In addition, a large amount of capillary ingrowth was seen in the pores. In the undifferentiated group, clusters ofround cells regarded to be marrow cells were recognized on the surfaces of the pores, and a small amount ofnewly formed bone was seen at the same site. In the control group, few cells were observed on the pore surfaces, and there was no evidence of new bone formation. The number of osteoclasts in the differentiated group was largerthan those in the other two groups.
    These results showed that differentiated bone marrow cell/bate-TCP composites had a high osteogenic potentialin an ectopic environment. In contrast, undifferentiated bone marrow cell/beta-TCP composites demonstratedlittle such potential. Differentiated bone marrow cells were thus suggested to play an important role in the boneformation and induction of osteoclasts on the composites.
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  • Nobuyoshi AOYAGI, Takashi KURODA, Kenzo OISHI, Toshiya SANO, Toshitaka ...
    2007 Volume 53 Issue 8 Pages 481-485
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    We report a case of serious injury to the oral mucosa resulting from the ingestion of a chemical agent.The severity of chemical injury to tissue depends on several factors, including the amount of agent involved, theduration of exposure, and the location of the affected site. It is important to immediately identify the cause ofchemical burns and to administer treatment quickly as damage will continue even after the chemical agent hasbeen removed.
    A 32-year-old man with schizophrenia swallowed sodium hydroxide in an attempt to commit suicide and wasbrought to our emergency room. An oral examination showed bilateral erosion of the buccal mucosa, soft palate, tongue, and lips. A tracheotomy was performed because of airway stenosis. The patient was instructed to garglewith azulene sodium sulfonate and to apply ointment on his lips. After 2 weeks, his condition improved and he wasdischarged from the hospital. Scar revision and skin grafting were performed as the patient was unable to movehis tongue for 5 months because of scar contracture of the sublingual region.
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  • Yasuhiro UENO, Yoshinori JINBU, Norito MIYAGI, Mikio KUSAMA
    2007 Volume 53 Issue 8 Pages 486-489
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    We present two cases of syphilitic cervical lymphadenitis with a hard chancre at the angle of the mouth.Case 1: The patient was a 46-year-old man. A medical examination revealed an indurated ulcer at the left angle ofthe mouth, with lymph node swelling in the left side of the neck. The swollen cervical lymph nodes were immobileand elastic hard on palpation, with tenderness. CT images revealed multiple swollen lymph nodes around the leftsubmandibular gland and in both the deep cervical and the left supraclavicular lymph nodes. Serological examinationrevealed elevated RPR (3+), TPHA test (2+), and FTA-ABS test (+) values.Cervical lymphadenitis dueto primary syphilis was diagnosed. Case 2: The patient was a 33-year-old man.A medical examination revealed anindurated ulcer at the right angle of the mouth and swollen lymph nodes in the right side of the neck. CT imagesshowed multiple swollen lymph nodes in the anterior portion of the right submandibular gland and in both thedeep cervical and submental regions. Serological examinations revealed elevated TPHA test (2+) and FTA-ABStest (+) values. Syphilitic lymphadenitis was diagnosed.
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  • Katsuhide NAGATA, Junko NAKAJIMA, Yasunori SATO
    2007 Volume 53 Issue 8 Pages 490-494
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    In general, mucoceles located in the floor of the mouth orsubmandibular region arise from a sublingualgland. Mucoceles originating from a submandibular gland are extremely rare. We report a case of mucocelearising from the submandibular gland.
    A 23-year-old man with a painless swelling in the left submandibular region was referred to our department.Extraoral examination revealed a fluctuant mass in this region. MRI showed a well-circumscribed lesion extendingfrom the submandibular gland to the base of the skull via the parapharyngeal space. The lesion emitted a high signalintensity on T2-weighted images.
    Surgical extirpation was carried out from the left submandibular triangle, and both the cyst and the submandibulargland were extirpated simultaneously under general anesthesia.
    Histopathological examination showed that the wall of the cyst had no epithelial lining, consistent with the diagnosisof an extravasation mucous cyst. There has been no evidence of recurrence as of 15 months after the operation.
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  • Goichi TSUKAMOTO, Takahiro KOYAMA, Shohei DOMAE, Tatsuo ONO, Hiroshi M ...
    2007 Volume 53 Issue 8 Pages 495-498
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    We report the case of a 6-year-old boy with a nasopalatine duct cyst. He consulted a dental clinicbecause of median diastema in the upper medial incisors. Radiographic examinations revealed a radiolucent areain the maxilla, extending from the nasal floor to the alveolar ridge between the medial incisors, which inclinedmedially. The upper lateral incisors were still impacted far from the normal position. We performed marsupializationto prevent damaging the incisor pulp. After that the lateral incisors erupted and malalignment of both incisorsimproved; however, the cystic cavity did not disappear completely. Extirpation of the remaining cyst followed bywound closure was performed at a secondary operation 9 months later. This case was considered to be rarebecause it occurred in childhood and affected the dental alignment at the time of teeth eruption.
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  • Mayumi MIYAHARA, Jun-ichi TANUMA, Kiyomi KAWASHIMA, Etsuro NOZOE, Ichi ...
    2007 Volume 53 Issue 8 Pages 499-503
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Calcifying epithelioma (pilomatrixoma) is a benign cutaneous tumor derived from skin appendages, such as pilomatrix. It is usually a solitary tumor and commonly found on the head, neck, and upper extremities inyoung-adult women; multiple occurrences are rare. Histopathologically, the tumor is composed of basophilic cellsand eoshinophilic shadow cells with occasional calcification and bone formation.
    A 20-year-old woman presented to our clinic with a 4-year history of amass arising in the inferior part of theright auricle. Examinations revealed two other solitary masses on both forearms. The tumor at the inferior part ofthe auricle showed marked calcification and ossification. We also clinicopathologically compared this case withfive previous cases. Wound healing was good 1 year and 6 months after surgery.
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  • Naoya KITAMURA, Kousei ISHIDA, Hiroyo DEGUCHI, Tsuyoshi HATA, Tetsuji ...
    2007 Volume 53 Issue 8 Pages 504-508
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Metastatic oral tumors generally carry a poor prognosis. It is therefore important to consider thepatient's quality of life (QOL) when planning treatment of metastatic oral lesions. In this article, we report a caseof transverse colon adenocarcinoma that metastasized to the maxilla and cervical lymph nodes 1 year after colorectomy.
    A 64-year-old man underwent surgery for transverse colon adenocarcinoma in January 2005 and received preoperativechemotherapy followed by secondary surgery because metastases to the iliopsoas muscle appeared in May2005. Because the patient's serum tumor marker levels increased again in October 2005 and he had swelling inhis left maxillary gingiva, he visited our hospital in January 2006. At presentation, the carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) levels were 18.1 and 689.9 ng/ml, respectively. Histologicalexamination of the gingival tumor revealed adenocarcinoma. Because distant metastasis was not detected in additionto the oral and neck lesions, we performed radical surgery of the oral and neck region. After surgery, theserum tumor marker levels of CEA and CA19-9 significantly decreased to 3.9 and 92.5 ng/ml, respectively. Thepatient is presently alive with no postoperative local recurrence or metastasis to other organs as of December 2006.
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  • Kosei ISHIDA, Satoshi ITO, Naoya KITAMURA, Hiroyo DEGUCHI, Tsuyoshi HA ...
    2007 Volume 53 Issue 8 Pages 509-513
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    The synchronous occurrence of histologically distinct tumors in the same parotid gland is rare, withonly a frequency of 0.2 % based on a report by Turnbull and Frazell. We report a case of pleomorphic adenomaand Warthin's tumor that occurred simultaneously in the same parotid gland.
    A 55-year-old man presented with a painless swelling in the left parotid region, present for 9 years. The patientvisited our hospital at this time because of a recent increase in the size of the swelling. The mass in the superiorpart of the parotid gland was elastic hard and clearly demarcated. In contrast, the mass in the lower pole of parotidgland was elastic soft and indistinctly demarcated.
    We evaluated the tumors by 99mTc salivary gland scintigraphy, 67Ga scintigraphy, ultrasonography, parotidsialography, and computed tomographic scanning. We also performed an aspiration biopsy of the tumor in thelower pole of the parotid gland to make a preoperative diagnosis. The tumor in the lower pole of the parotid glandwas strongly suspected to be a Warthin's tumor, while the tumor in the superior part was considered to most likelybe a benign tumor. These tumors were resected by a superficial parotidectomy. As for the histopathologicaldiagnosis, the tumor from the lower pole was confirmed to be a Warthin's tumor, while the tumor in superior partturned out to be a pleomorphic adenoma.
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  • Tetsuya OTSUKI, Munenori YASUDA, Yoshizo TSUDA
    2007 Volume 53 Issue 8 Pages 514-518
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    We report a rare case of nasal type natural killer T cell (NK/T cell) lymphoma with severe swelling ofthe upper lip.
    A 67-year-old man was referred to our hospital because of swelling of the upper lip. The diagnosis was difficultbecause of extensive tumor necrosis. A definite diagnosis of NK/T cell lymphoma was made on the fourth biopsyof the upper lip.
    The tumor responded well to radiation therapy followed by 3 courses of DeVIC (dexamethasone, VP16, ifosfamide, carboplatin) combination chemotherapy. After this therapy, patient has remained free of symptoms andrecurrence.
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  • Ikuya MIYAMOTO, Hiroyuki TAKAFUJI, Kazumasa NAKAO, Ikuko NAKANO, Yoich ...
    2007 Volume 53 Issue 8 Pages 519-523
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    This report describes occlusal reconstruction in a 23-year-old man with cleidocranial dysplasia (CCD).It is often difficult to perform dental treatment in patients with CCD because of complicated skeletal and alveolarabnormalities. First, endosseous implants were used to restore the mandibular molar region. After careful examinations, Le fort I type osteotomy was performed with distraction osteogenesis to advance the maxilla.Subsequently, implants were used to restore the maxillary arches with a fixed prosthesis. After the provisionalrestoration, the final prosthesis was set. The most recent follow-up, 1 year after the final treatment, confirmed asatisfactory treatment result.
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  • Junko TANAKA, Ken OMURA, Yuzo TAKAHASHI, Zenzo MIWA
    2007 Volume 53 Issue 8 Pages 524-528
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Marfan's syndrome (MFS) is a dominantly inherited connective tissue disorder caused by mutationsin the FBN1 gene. The disease affects mainly the skeletal, cardiovascular, and ocular systems. In the oral region, MFS is often associated with a high-arched and narrow palate, with crowding and impaction of the teeth.
    The condition of the periodontal membrane is an important determinant of the successful autotransplantation ofteeth.
    We believe that this is the first report to document the autotransplantation of teeth in a patient with MFS. A 14-year-old boy was referred to the Department of Oral and Maxillofacial Surgery, Tokyo Medical and DentalUniversity because of malocculusion. Intraoral and X-ray examinations revealed crowding of the teeth, supernumeraryteeth, and impaction of the inverted upper central incisor. After consultation with orthodontists andpedodontists, he underwent extraction of the supernumerary teeth and concurrent transplantation of the impactedupper right central incisor to the original position. Before transplantation, the incisor was apicotomized because ofsevere root tip curvature. The postoperative course was uneventful. The upper central incisor underwent rootcanal filling 3 weeks after transplantation, and orthodontic treatment, including the transplanted incisor was successfullystarted 3 months after transplantation. The transplanted incisor is surviving with no evidence of abnormalroot resorption and is functioning well.
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  • Masahito MAEDA, Yasuo KINOSHITA, Akiko KATSURAGI
    2007 Volume 53 Issue 8 Pages 529-533
    Published: August 20, 2007
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    We report a pseudoaneurysm that developed after tooth extraction and was treated by transcatheterarterial embolization (TAE). The patient was an 84-year-old woman. Immediately after lower second molar extraction, remarkable swelling developed in the sublingual region. Slightly prolonged bleeding from the second molarregion of the right lower jaw was noted after extraction. The bleeding was controlled by local hemostatic material.On the third day after the extraction, swelling of the sublingual region increased and extended to the floor of themouth. The site corresponding to the wound after extraction showed a pseudoaneurysm on cystographic MRI. Weperformed hemostasis by TAE. The day after TAE, the pseudoaneurysm had disappeared on cystographic CT.The postoperative course was uneventful, without further bleeding.
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