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Volume 42, Issue 2
Displaying 1-19 of 19 articles from this issue
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Masamichi ITA, Tsukasa KUZUYAMA, Yuka MIMURA, Tatsuo TSUJI, Masaki OKA ...1996 Volume 42 Issue 2 Pages 141-146
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSWe have established a new cell line, KM-5, which is derived from human squamous cell carcinoma of the lower gingiva. KM-5 cell line is characterized by monolayer growth and polygonal cell shape; the doubling time is approximately 23 hours. Cytokeratin and epithelial membrane antigen (EMA) were immunohistochemically positive, indicating that KM-5 cells were derived from epithelial cells.
The histological appearance of tumors transplanted into nude mice were similar to that of the original tumor, but the nucleus/cytoplasm (N/C) ratio, hyperchromatism and nuclear polymorpholism changed slightly during the process of culture. DNA content and chromosome number were investigated from the origin to 50th passage of KM-5 using flow cytometry and fluorescence in situ hybridization method with centromere specific DNA probes of chromosomes 1, 4, 11, and 17.
DNA index of the original tumor was 1.0, which indicated DNA diploidy; however, those of cell lines from the 2nd to 50th passages were consistently around 1.3, which indicated DNA aneuploidy. DNA index apparently did not change dramatically during cell culture. Numerical aberrations of chromosomes 1, 4, 11, and 17 were observed in each passage. Interestingly, the percentage of monosomy of chromosomes 1 and 11 markedly increased in early phase of cell culture. After the 30th passage, however, this percentage decreased, and the variation of chromosomal aberrations seemed to be the same in these chromosomes. To summarize our results, the time of stabilization seemed to be the 2nd passage for the DNA index, and the 30th passage for numerical aberrations of chromosomes 1, 4, 11, and 17.View full abstractDownload PDF (7497K) -
Takashi SEKIGUCHI, Makoto NOGUCHI, Hiroyoshi HIRATSUKA, Kenji NAKAMORI ...1996 Volume 42 Issue 2 Pages 147-154
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSBiopsy specimens from 51 patients with untreated oral squamous cell carcinomas (oral SCC) were examined with monoclonal anti-type VII collagen antibody to study the localization of type VII collagen at the invading edge of tumors and the relation between such localization and clinical and pathological characteristics. The results are summarized as follows.
1. According to the immunostaining of type VII collagen, all apecimens could be divided into the following four groups: an intact, continuous linear pattern of immunostaining for type VII collagen around the cancer nests (9 /51, 17.6%); an interruption or attenuation of immunostaining (12/51, 23.5%); a deposition or loss of immunostaining (14/51, 27.5%); and alteration of type VII collagen deposition associated with lymphocyte infiltration into the cancer nests (16/51, 31.4%).
2. The immuno-localization of type VII collagen was closely related to the degree of differentiation of cancer cells, the degree of cellular atypia and mitotic index, the mode of cancer invasion, and the degree of lymphocytic infiltration.
In conclusion, the results of this study suggest that the immuno-localization of type VII collagen at the invading edge of tumors may reflect the histological malignancy of oral SCC.View full abstractDownload PDF (5841K) -
Toshihiro NAKAMI, Yasuo ISHII, Kaihei HAYASHI, Masahiro TUZUKI, Manabu ...1996 Volume 42 Issue 2 Pages 155-158
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSTo shorten the treatment period and to prevent relapse, Köle recommends that corticotomy be performed in adults who undergo orthodontic treatment and in persons in whom such treatment is delayed. However, Köle's method has disadvantages such as gingival recession and resorption of the alveolar crest, because it entails cutting the alveolar crest with a bur. To avoid these disadvantages, we modified Kole's method and cut the alveolar crest with only a chisel.
This modified procedure was performed in 19 patients undergoing preoperative orthodontic treatment for maxillofacial deformity and in 5 patients receiving adjunctive treatment for conventional orthodontic therapy. With this procedure, the duration of tooth movement was shortened and no complications, including recession of the interdental papilla, occurred during the course of treatment. The esthetic outcome was also satisfactory.View full abstractDownload PDF (3085K) -
Hiroyuki KINOSHITA, Toshihiko KAWAI, Kanji KOMAKI, Toru NAGAO, You MUK ...1996 Volume 42 Issue 2 Pages 159-163
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSWe evaluated the postoperatively nutritional status in 21 patients (5 males; 16 females) with maxillofacial deformity who were given a low residue diet. The energy content of the diet was 1 kcal/ml. We administered 1, 000 kcal/day on the first day, and increased the dose by 200 kcal/day daily until a full strength of 2, 000 kcal/day was achieved. The diet was then given for 14 days with a naso-gastric feeding tube. We examined blood chemistry, blood count, and nitrogen balance and measured body weight on preoperative day 1 and on postoperative days 1, 7, and 14.
On the first day, total protein, albumin, and rapid turnover protein decreased because of the surgical damage. These variabled showed improvement on day 7. On day 14, 20 patients (95%) had improved nutritional status, as compared with their preoperative status. The nitrogen balance became positive in all patients by day 7. We could not find any clinical problems, including changes in body weight and laboratory examinations for liver or renal function, serum electrolyte levels, and blood counts. As for side effects, 4 patients had diarrhea, but did not have to decrease the quantities of their low residue diet. All patients showed a rapid improvement in their nutritional items without side effects under this nutritional program.
Low residue diet Sanet-V® was useful for the postoperative nutritional management of patients with maxillofacial deformity and the resolution of surgical damage.View full abstractDownload PDF (571K) -
Kazuhide SEKO, Hideki MIZUTANI, Katsuhiro SENGA, Kazuki YASUE, Hisashi ...1996 Volume 42 Issue 2 Pages 164-169
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSThe pathological features of closed lock involving anterior disc displacement without reduction have been elucidated by recent investigations. However, bilateral MRI scans of patients with unilateral TMJ symptoms demonstrated the presence of abnormal findings of the contralateral TMJ disc. Treatment procedures for such cases have yet to be established, and their underlying pathological features are not fully understood.
This study was designed to elucidate the effects of conservative treatment for bilateral closed lock and the correlation between disc configuration, based on MR imaging, and clincal findings.
The following results were obtained:
1. Our non-surgical treatment was successful in 65% of patients with bilateral closed lock of the TMJ. The efficacy of pumping manipulation of the TMJ with poor mobility (high rigidity on manipulation) in the absence of symptoms was suggested.
2. The disc configuration on MR imaging indicated a high frequency of folding type and non-structured type among symptmatic TMJ and a high frequency of even thickness type among non-symptomatic TMJ.View full abstractDownload PDF (714K) -
Hiroshi IWABUCHI, Kaori YAGO, Youichi TANAKA, Tetsuya IMATANI, Hiromas ...1996 Volume 42 Issue 2 Pages 170-175
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSWe comparatively studied differences in clinicopathological features according to the keratin type of the epithelium of the cyst wall and differences in cell kinetics using antibodies against PCNA in 33 patients with odontogenic keratocysts (36 cysts). The subjects presented at the patient clinic of our department during the 17 years from 1979 to 1995 and satisfied the histopathological criteria described by Pindborg et al. When classified according to the keratin type of the cyst-wall epithelium, there were 7 (19.4%) cysts with orthokeratin (group I), 5 (13.9%) cysts with parakeratin accompanied by partial orthokeratin (group II), and 24 (66.7%) cysts with parakeratin (group III). The average age of group I was slightly younger than that of group III. The number of women was higher than that of men in group I, while men slightly outnumbered women in the group M. No cysts in group I were associated with basal cell nevus syndrome. The form of all cysts was unilocular in the group I, while in group III, cysts showed various forms, including multilocular cysts. The number of cysts with impacted teeth was higher in group III than in the other two groups. The size of some cysts was 8 cm or larger in group III, while in the group I, there were no cysts of 8 cm or larger. No significant differences were observed in the PCNA-positive rate between group I and III.View full abstractDownload PDF (3373K) -
Toshio HARADA, Shin-ichi NAITOH, Takahiro MIKAMI, Yasuro YOSHIMURA1996 Volume 42 Issue 2 Pages 176-178
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSTwo cases of primary intraosseous carcinoma (PIOC) are reported. One PIOC developed in the anterior maxilla of a 44-year-old man and appeared as carcinoma arising in a radicular cyst. The other PIOC appeared in the mandible of a 41-year-old man and was diagnosed as a PIOC arising from an odontogenic cyst. The first tumor subsequently metastasized to the regional lymph nodes. However, the second tumor did not metastasize to any regional lymph nodes. These patients are free of the disease as of two years and six months and one year and seven months, respectively, after treatment.View full abstractDownload PDF (5116K) -
Takuya TOKUNAGA, Tamotsu MIMURA, Etsuro NOZOE, Kazuhide NISHIHARA, Ich ...1996 Volume 42 Issue 2 Pages 179-181
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSChondrosarcoma is difficult to diagnose and it is extremely rare in the maxillofacial region. A case of chondrosarcoma arising in the anterior region of the maxilla is reported.
A 43-year-old woman consulted our clinic with a chief complaint of painless swelling at the anterior region of the maxilla.
As examination of a biopsy specimen suggested a chondroid tumor, the tumor was excised under general anesthesia. Histopathological examination revealed that the tumor was a chondrosarcoma. Since the tumor was seen at the surgical margin, the patient underwent partial resection of maxilla and a split-thickness skin graft.
Histopathologically, the tumor consisted of atypical chondroid tissue with marked ossification and showed invasive growth.
The chondroid tumor cells showed pleomorphism and atypism.
There has been no sign of recurrence or metastasis as of 3 years after operation.View full abstractDownload PDF (2840K) -
Treatment by implantation of solvent-dehydrated human duraMichio KAWAI, Hideki MIZUTANI, Takashi TERAMOTO, Tamaki ASAHINA, Yoshi ...1996 Volume 42 Issue 2 Pages 182-184
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSGustatory sweating (Frey's syndrome) presents as localized flushing and sweating of the skin in the anterior region of the ear lobe and the temporal region after a certain period of time after surgery or trauma to the region of the parotid gland or the angle of the mandible over the site of the parotid bed. It is an intractable disease, and effective therapy has not been established yet.
We report a case of gustatory sweating that occurred after radical neck dissection. A 65-year-old woman underwent radical neck dissection for cervical metastasis of maxillary cancer. The post operative course was uneventful, and there was after no local recurrence or distant metastasis in the year after operation.
However, the patient complained of gustatory sweating near the operative region, and Minor's starch iodine test was positive.
We attemped to treat gustatory sweating by subcutaneously implanting solventdehydrated human dura mater in regions of the skin where sweating and flushing were observed.
There was no evidence of a foreign body reaction, infection, or other adverse reactions as of 1 year after dura implantation.
Therefore, this method is useful in the treatment of Frey's syndrome.View full abstractDownload PDF (2681K) -
Takeshi MIZUMOTO, Hiroyuki HAMAKAWA, Toshiko MIYOSHI, Manabu TAKARADA, ...1996 Volume 42 Issue 2 Pages 185-187
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSOsteochondroma is composed of bony and cartilagenous tumor elements.
Its occurrence at the mandibular coronoid process is relatively rare.
A 43-year-old man was referred to our hospital with a chief complaint of severe trismus. His mouth could be opened by only 11mm.
A 3×4cm mushroom-like mass was detected at the left coronoid process by computed tomography.
A transzygomatic approach was used under general anesthesia. A frontotemporal curve skin incision was made to expose the zygomatic region. After removal of the zygomatic arch, the tumor was excised with the coronoid process.
The resected zygomatic arch was reconstructed with the outer cortical layer of the frontal bone. Postoperative limitation of mouth opening was remarkably improved.
The amount of mouth opening increased to 23mm immediately after operation, and remarkably improved to 49 mm after one year.View full abstractDownload PDF (2790K) -
Akio TAKEDA, Akiko LEE, Yasuyuki ODA, Itsuro KUDO, Kaoru KUSAMA, Itaru ...1996 Volume 42 Issue 2 Pages 188-190
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSWe describe a case of unicystic ameloblastoma in the left lower wisdom tooth region in a 16-year-old girl. Clinical examinations showed typical features of a dentigerous cyst. Although a lining epithelium was observed in the unicystic lesion, tumor nests characteristic of an enamel organ were also present as lining epithelial elements, and island-like and mass-like regions of ameloblastoma were found in the connective tissue of the cystic wall. Small amounts of calcified materials were noted in the tumor nests. These findings suggested that this case was an unusual unicystic ameloblastoma derived from the epithelium lining a follicular detal cyst.View full abstractDownload PDF (2738K) -
Kikuko MAEDA, Masanobu OHNISI, Masahiro FURUTANI, Mineo KAWAI, Sin-ich ...1996 Volume 42 Issue 2 Pages 191-193
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSEosinophilic ulcer of the oral mucosa mimics oral cancer clinically and is occasionally misdiagnosed as lymphoma on microscopic examination. Trauma is believed to play a role in its development, but its exact pathogenesis is not known. A case of eosinophilic ulcer of the tongue in a healthy 17-year-old man is presented. The lesion healed spontaneously with no active treatment.
To the best of our knowledge, no case of eosinophilic ulcer has been reported previously in Japan. The demographic characteristics of cases of eosinophilic ulcer of the oral mucosa reported in the international literature are briefly reviewed.View full abstractDownload PDF (2878K) -
Michio KANEKO, Kenji YOSHIDA, Takashi TAKEMOTO, Yasuhiro ITO1996 Volume 42 Issue 2 Pages 194-196
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSThis paper describes a case of eosinophilic granuloma of the soft tissue in the cheek. The patient was a 52-year-old man, who was a repairman of vintage cars. He had a history of inhaling large quantities of dust.
Preoperative hematologic examination showed a white blood cell count of 5600 with 12% eosinophils. A radioimmunosorbent test (RIST) revealed an immunoglobulin E level of 5217.3 IU/dl. In antigen examinations, antibodies against house dust and ticks were abnormal on radioallergosorbent tests (RAST) of immunoglobulin E.
The lesion was enucleated under GO-NLA. The patient was also provided guidance how to improve his work environment.
There is no evidence of lesion recurrence as of 14 months after operation.View full abstractDownload PDF (4457K) -
Hajime MASHIMO, Katsuhiko MUNEKAWA, Gen-ichi TAKEDA1996 Volume 42 Issue 2 Pages 197-199
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSWe report a case of Osler-Weber-Rendu disease occurring in the oral mucosa. A 56-year-old woman visited our clinic complaining of blood oozing from the oral mucosa. The patient had received treatment for anemia for about 30 years. The involvement of hereditary factors was suspected because of her grandfather, mother and two sisters had hemorrhagic diseases. We observed peripheral vasodilation of the oral mucosa of the patient, but there were no gross signs of bleeding. We treated part of the oral mucosa by cryosurgery.View full abstractDownload PDF (4075K) -
Masashi TANAKA, Munekazu SUZUKI, Makoto YOSHIDA, Hiroko HOSHINO, Takah ...1996 Volume 42 Issue 2 Pages 200-202
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSWe describe a 39-year-old man suffering from cleidocranial dysostosis associated with multiple impacted teeth. He was first seen in our hospital for a complaint of brasymasesis. The patient was of somewhat small stature with dysplasia of the bilateral clavicles and a bell-shaped thorax. His face had an inverted pear-shaped appearance and a saddle nose. There was dysplasia of the fontanel and frontal sutures, and incomplete sutures in the sutura coronalis and the sutura sagittalis of the skull. Eight impacted teeth were found in the jaw bones. In addition, marked pelvic narrowing was also seen. 6531 and 5 5 were extracted because they could not be preserved. Although the induction of impacted teeth 43 and 45 back into the dentition was initially planned, .these teeth were extracted because of his age and because the induced teeth would not be useful in the future prosthesis. For 123, the root canal was treated and a coping was applied in order to attach the artificial tooth.View full abstractDownload PDF (2482K) -
Takashi TACHIMURA, Koichi SATOH, Hisanaga HARA, Takeshi WADA1996 Volume 42 Issue 2 Pages 203-205
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSPharyngeal flap surgery may be used to correct hypernasality following primary palatal closure with a pharyngeal flap to create airway resistance. Obstructive sleep apnea has been reported to be one of the serious complications after operation. However, there has been no report made on how to predict postoperative changes in sleep condition. This article attempts to estimate the possibility of predicting postoperative changes in sleep condition with the need ratio (NR), based on the velopharyngeal distance divided by the velum length, which is obtained from lateral cephalograms taken preoperatively. Fifteen patients who underwent unified velopharyngoplasty to correct velopharyngeal incompetence were selected as subjects. Oxygen saturation during sleep was recorded daily after operation in all subjects. The lowest value of mean SpO2(Lo-SpO2) was considered to be representative of postoperative sleep condition. Statistical analysis showed a significant correlation between Lo-SpO2 and NR. It was suggested that NR could be an indicator for postoperative sleep changes.View full abstractDownload PDF (501K) -
Takashi MIKI, Noriko TACHIKAWA, Mitsuo ODA, Toshiaki KURACHI, Eiki SAK ...1996 Volume 42 Issue 2 Pages 206-208
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSA dentigerous cyst associated with a permanent tooth is frequently encountered a type of odontogenic cyst, but this cyst rarely arises in a deciduous tooth. We describe a one-year-old boy with a dentigerous cyst of a deciduous canine tooth. Marsupialization of the cyst was performed with the patient under general anesthesia. Presently, about one year after operation, the canine tooth has completely erupted and is functioning normally.View full abstractDownload PDF (2667K) -
Yasuhiro OKAZAKI, Hideaki KAGAMI, Toshio SHIGETOMI, Minoru UEDA1996 Volume 42 Issue 2 Pages 209-211
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSA case of a gigantic sialolith in the submandibular gland is reported. The patient was a 59-year-old woman. X-ray and CT examination showed a large radiopaque mass in the submandibular region. The submandibular gland was almost occupied by the sialolith. The submandibular gland was removed under general anesthesia, and a mass was found in the submandibular gland. The sialolith was 42mm in diameter and weighed 14g. The pathological diagnosis was a sialolith. The large size of the stone precluded diagnosis. CT and Tc scintigraphic examinations had an important part in the clinical diagnosis of this case.View full abstractDownload PDF (2571K) -
Yoshinari MORIMOTO, Minoru YOSHIOKA, Masanori ITAHASHI, Masaki FUJIMOT ...1996 Volume 42 Issue 2 Pages 212-214
Published: February 20, 1996
Released on J-STAGE: July 25, 2011
JOURNAL FREE ACCESSThis report describes a 58-year old man with schizophrenia who inserted a foreign body (injection needle) into the cervical region.
The patient visited our clinic 22 days after the episode. The inserted needle was identified inside the left submandibular gland area on preoperative CT scan. During operation, the needle could not be found in the area, and it was found to have moved to a more inferior region on intraoperative X-ray examination. The needle was then detected between the common carotid artery and the internal jugular vein and was removed successfully.
We conclude that the location of foreign bodies should be confirmed by X-ray examination before removal.View full abstractDownload PDF (2567K)
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