Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Volume 32, Issue 7
Displaying 1-25 of 25 articles from this issue
  • Hiroyuki HAMAKAWA, Tadashi DOI, Izumi HYODO, Keizo MORI, Hiroaki TANIO ...
    1986 Volume 32 Issue 7 Pages 1109-1120
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Histogenesis of the salivary gland tumor is controversial due to the variety of histopathologic features.Recently, localization of various antigens and cytoskeletal filamentous proteins have been morphologically identified, as the immunohistochemistry developed.
    In the present study, 70 cases of salivary gland tumors removed surgically in our hospital were stained immunohistochemically.Antibodies used for immunostaining were S-100 a, lactoferrin (LF), secretory component (SC), CEA, keratin, prekeratin, myosin as the polyclonal antibody, and S-100 b, PKK-1, vimentin as the monoclonal antibody.
    Positive immunostaining for S-100 a was only observed in pleomorphic adenoma. All of chondroid cells and some of spindle cells, epithelial tumor cells showed intense immunoreactivity for S-100 a.
    LF was predominantly positive in pleomorphic adenomas and was stained in a few cases of adenolynphoma, adenoid cystic carcinoma and adenocarcinoma.SC reacted positively not only in LF positive tumors but also in 50% of mucoepider moid tumors.The positive rate for CEA was 22% in benign tumors and 50% in malignant tumors.
    Keratin and prekeratin thought to be the epithelial tumor markers were frequently stained in almost all tumors.Myosin-positive cells were localized in some of spindle cells, chondroid cells in pleomorphic adenoma, and also some of undifferentiated polygonal cells in adenoid cystic carcinoma.
    According to the immunohistochemical staining pattern, the following results were concluded.
    1) S-100 a stained pleomorphic adenoma specifically.
    2) Duct-like structure in pleomorphic adenoma retains the function of production of LF and SC in accordance with functional differentiation.
    3) Regezi's bicellular theory presents a reasonable explanation of the origin of the salivary gland tumor.
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  • Shigetomo IGA
    1986 Volume 32 Issue 7 Pages 1121-1138
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    The root resorption affected by the ameloblastoma, odontogenic cyst, fibrous dysplasia, ossifying fibroma and cementifying fibroma were observed.The degree of root resorption were classified by the characteristic of the clinical X-ray findings into 5 types.
    Type A: shows severe resorption with a saw-toothed root.
    Type B: shows severe resorption with a sharp-cut root.
    Type C: shows moderate resorption with the rough surface of the root.
    Type D: shows absence of lamina dura and loss of periodontal ligament space without root resorption.
    Type E: shows hypercementosis of the root.
    Roots of the extracted teeth involved in the lesions were observed morphologicaly and compared with clinical X-ray findings.
    Also, the surfaces of affected roots were observed with a scanning electron microscope.The results are concluded as follows.
    1. The incidence of the root resorption affected by the ameloblastoma, ossifying fibroma and cementifying fibroma were higher than that of the odontogenic cyst and fibrous dysplasia.
    2. The findings of scanning electron microscope showed various degrees of demineralization and remineralization in the lesions.
    3. In 71.2% of the extracted teeth having lesions, the characteristics of the root resorption were reviewed previously in clinical X-ray findings.
    The results may aid the clinician in the preoperative differential diagnosis.
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  • Kenichi SASAKI, Hitachi MASAKI, Shin MIYAKE, Mitsuru YAMA, Kyouko KAME ...
    1986 Volume 32 Issue 7 Pages 1139-1149
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Several types of osteotomy have been performed for correction of mandibular prognathism, retrognathia and assymmetry.The injury of the inferior alvolar nerve as a complication were evaluated in 35 patients after the surgery.
    1. Anesthesia, hypesthesia and paresthesia of the lip and mental area were observed in all of the patients (35 cases) in early stage after the operation.
    2. 70.8% of the patients who were treated with sagittal splitting osteotomy were recognized as S4 (Highet's standards) within a year.
    3. The Average of the sensory nerve conduction velocity (S.C.V.) of normal was approximately 60m/sec.Nerve action potential could not be recorded in early stage and gradually returned to normal S.C.V.from 20 weeks after the surgery.
    4. Complete return of the sensation was recognized within 40 weeks after the operation which mandible were moved less than 10mm.
    5. There is no difference of return of sensation between circumferencial wiring and bone screw fixation after sagittal splitting osteotomy.
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  • Healing process under short-term intermaxillary fixation in cases of non-displaced minor fragment
    Masashi SHIMAHARA, Katsumi ONO, Yoshinobu NAKANO, Ayako MIZUKAWA, Hide ...
    1986 Volume 32 Issue 7 Pages 1150-1156
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    In cases of fracture of the condylar process of the mandible, especially those occurring unilaterally, conservative treatment consisting of short-term intermaxillary fixation ordinarilly achieves good results with a favorable prognosis.However, with regard to the indcations for this treatment, little detailed investigation or supporting experimental research has been reported.
    In this study, using mature rats, after one week of inter-maxillary fixation, the bone healing process was investigated in relation to performance of mastication movement.
    One week following bone fracture, that is, at the time of remove of intermaxillary fixation, all the cases of interior displacement of the minor fragment had recovered and showed normal positioning.However, from the second week following removal of intermaxillary fixation, shrinkage of the head of the mandibular condyloid process was evident, with this tendency continuing up to the sixth week.Formation of replacement bone did include some cartilaginous ossification, but consisted mostly of intramembranous ossification.At the time of removal of intermaxillary fixation, no healing of the bone fracture was evident, however during the second week following the bone fracture, or the first week following removal of intermaxillary fixation, the process began and bone healing was visible in some cases, and in third week it was visible in all cases.During the sixth week, normal medullary cavities and tissue were also seen.Observation at six months following bone fracture revealed some shrinkage of the head of the mandibular condyloid process in few cases, but for the most part, observations were normal.
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  • Hiroshi MIYAJIMA, Meigou TAKANOHASHI, Eisaku MORII, Fukashi ADACHI, Ka ...
    1986 Volume 32 Issue 7 Pages 1157-1163
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    In order to prolong the serum consentration, long ating Amoxicillin (L-AMPC) prescribed the mixtures of 30% of non-coated granules and 70% of enteric-coated granules dissolvable on and above pH 6.
    In the present study, the serum concentration of L-AMPC and AMPC was examined using a time lapse for determining its optimum dose and frequency of administration.A cross over test for L-AMPC and AMPC was performed in 4 healthy male adults.Four groups were examined;Group I L-AMPC 500 mg, twice a day;Group II L-AMPC 500 mg, three times a day;Group III AMPC 250 mg, three times a day;Group IV AMPC 250 mg, four times a day.The serum concentration was monitered on and after the first administration for 24 hours.The determination of serum levels was performed on serum samples by a cylinder method.
    The serum effective hour (MIC: 1.56μg/ml) was 15.0 hours in Group I, 19.9 hours in Group II, 10.7 hours in Group III, 11.7 hours in Group IV. The serum AUC (MIC: 1.56μg/ml) was 15.724μg·hr/ml in Group I, 20.580μg·hr/ml in Group II, 7.856μg·hr/ml/ml in Group III, 11.793μg·hr/ml in Group IV.
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  • Hideharu SUZUKI, Toshio KANEDA
    1986 Volume 32 Issue 7 Pages 1164-1172
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Since high-concentrate thrombin preparations have excellent effectiveness for local hemostasis in patients with coagulopathies, the blood coagulation mechanism in the presence of high-concentrate thrombin, using purified thrombin and plasminogen-free fibrinogen was investigated.
    1) The blood coagulation analyzer, Coag-Stat was utilized in the kinetic study of fibrinogen to fibrin transformation.The initial velocity of fibrin formation was accelerated as the concentration increased and the amounts of fibrin were gradually decreased in relation to the given amount of sodium heparin.The general result of this investigation was that anti-thrombin III and a large amount of heparin caused neutralization of dosage of 100 units/ml thrombin with neutralization increasing with heparin dosage.
    2) The influence of coagulum stiffness, which depended on the thrombin dose, was investigated by thrombelastograph.The higher concentration thrombin solutions above 10 units/ml dosage had indicated a fibrinolytic activity by reason of “ma” value decrease.This was particularly remarkable with dosages of 100 units/ml and 1, 000 units/ml thrombin.
    3) The progress of the digestion of fibrin by high-concentrate thrombin was also monitored by SDS-polyacrylamide gel electrophoresis of the lysed fibrin at frequent intervals during the 180 minute digestion period.The gels stained with Coomassie blue, which were applied to plasminogen-free fibrinogen, showed the α, β and γ chains. After 60, 120 and 180 min of digestion the α chains were present in much smaller amounts and appear to have been extensively degraded.
    4) From the standpoint of prophylactic and continual effectiveness in postoperative bleeding, we also examined the diffusion state of high-concentrate thrombin from the fibrin network. In the investigation of thrombin diffusion, high-concentration thrombin was diffused on an agarose plate, containing plasminogen-free fibrinogen, and was seen to precipitate an increasing amount of fibrin.
    From the result of these study, the accelerative function of thrombin in blood coagulation was again confirmed.High-concentrate thrombin penetrated and diffused into the fibrin network during a period of several hours.We presume that this function produces continual hemostatic efficacy.In a practical clinical application of thrombin, it seems that the plasma inhibitor and released heparinoid affect the preparation.From this experiment about 100 units/ml of thrombin were neutralized under AT-III and extra doses of heparin.Moreover, taking many kinds of plasma inhibitors into consideration, this approach showed that clinically more than 1, 000 units/ml thrombin was more effective.
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  • Shigeru TOMITA, Hitoshi TAKAMORI, Ryutaroh KOBAYASHI, Kohjyu KARUBE, S ...
    1986 Volume 32 Issue 7 Pages 1173-1191
    Published: July 20, 1986
    Released on J-STAGE: September 13, 2011
    JOURNAL FREE ACCESS
    Various surgical orthodontic procedures are currently employed for the correction of jaw deformities.A postoperative problem, relapse, seems to be due to an imbalance of the perioral muscular groups resulting from changes in the cavitas oris propria after surgery. Among other factors, it is widely known that the effect of the tongue, i.e., tongue pressure, is greatly involved in such relapse, but no detailed reports on this matter have been available.
    In the present study, in 15 patients who underwent retropositioning of the mandible by sagittal splitting osteotomy or mandibular body step-ostectomy, the tongue pressure during deglutition of saliva and water and during maximal anterior position were determined before and after surgery.In addition, changes in tongue pressure during various movements were analyzed in combination with standerd X-ray films of the head taken during those movements. The relation of tongue pressure to changes in the jaw before and after retropositioning of the mandible was thus investigated by comparing the two surgical methods, and the folowing findings were obtained.
    1. Tongue pressure tended to increase both after sagittal splitting osteotomy and mandibular body step-ostectomy.
    2. In patients who underwent sagittal splitting osteotomy, tongue pressure tended to increase gradually from 3 to 12 months after surgery, the mandibular position changing in a forward direction from 6 to 12 months along with the increase.In Patients with mandibular body stepostectomy, tongue pressure was not markedly altered from 3 months after surgery, the mandibular position also showing no marked changes from 3 months after surgery.
    3. These changes in tongue pressue, however, varied in different individuals, and whether an increase in tongue pressure correlates with the degree of relapse remains to be clarified.
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  • Kazuyuki FUKUSHIMA
    1986 Volume 32 Issue 7 Pages 1192-1212
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Foetor ex ore, or bad breath has been regarded as an ordinary symptom associated with the regional and systemic disorders.The main cause of bad breathis regarded as oral cavity origin.Although a number of former investigators found a lot of ingredients of bad breath, it is considered that the three volatile sulfur compounds (VSC) are the most important ingredients which relate to the organoleptic ratings.The most important VSC are as follows, hydrogen sulfide (H2S), methyl mercaptan (CH3SH) and dimethy sulfide ((CH3) 2S).Using the gas chromatography, the author, first, investigated the thresholds of objectionability for these three VSC, then quantitative changes, relationship between oral conditions and VSC, and effect of mouth cleanliness on all these VSC derived from 24 healthy persons free from regional or systemic disorders in an ordinary or experimental conditions.The results were as follows:
    The study showed that H2S, CH3SH and (CH3) 2S concentrations below 0.62ng, 0.29ng and 0.04ng/5ml, respectively, are considered nonobjectionable.
    Though the author investigated the persons who have no or physiological mouth odor, the relation was found between the amount of tongue coating and concentrations of these VSC (H2S-r=0.798, CH3SH-r=0.557, (CH3) 2S-r=0.680).
    This time, it was recognized that the effect of mouth cleanliness without dentifrice lasted for up to 90 minutes when it was prohibited to take such measures for one entire day, but not in other conditions, or when the mouth cleanliness measures were prohibited for two or three days.
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  • Takumi ARIKA
    1986 Volume 32 Issue 7 Pages 1213-1232
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    The author investigated the effects of a radioprotective agent (YM 08310=WR-2721) on osteoradionecrosis of the mandible. External X ray irradiation was performed on right side of the mandible.The dosage of irradiation was 3000 R.The rabbits were administrated of YM 08310 100mg/kg or 200mg/kg intra-venously 30 min.before irradiation.
    The results were the following.
    1. Group without YM 08310 (only irradiation): One month after irradiation, there was almost no resorption of bone observed. 3 months after irradiation, most of the cortical bone was resorbed and was replaced by fibrous connective tissue.The formation of new bone by endosteum also was observed.6 months after irradiation, some dead bone was replaced by new bone, but in the cortical bone there was still bone resorption observed.
    2. Group with YM 08310 100 mg/kg: One month after irradiation, there was almost no bone resorption observed.3 months after irradiation, there was resorption in cortical bone, and the formation of new bone by the periosteum and the endosteum observed.6 months after irradiation, there was still a little resorption in the cortical bone but vigorous bone formation was observed.
    3. Group with YM 08310 200 mg/kg: One month after irradiation, there was almost no bone resorption observed.3 months after irradiation, there was no dead bone and no remarkable resorption obseved and the same findings were observed for 6 months after irradiation.
    From these results, the author drew the following conclusion.
    1. There were effects of YM 08310 on osteoradionecrosis observed, and the effects were more prominent in the group with 200 mg/kg than in that with 100mg/kg.
    2. In the group with YM 08310 100 mg/kg, there were still bone addition and repair by periosteum after irradiation, and that was due to the effect of YM 08310 on periosteum.
    3. In the group with YM 08310 200 mg/kg, there was a remarkable effect of YM 08310 on the bone and this agent could prevent osteoradionecrosis.
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  • Yoshihiro OKAMOTO, Akihide KAMEGAI, Shuji KURENUMA, Kuniteru NAGAHARA, ...
    1986 Volume 32 Issue 7 Pages 1233-1237
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Dental managements in a 17 year old male patient with thrombocytopenia were performed to provide adequate care for post operative bleeding.The patient had been treated with immunosupresive agent therapy and splenectomy, but an elevation of the platete level in the blood did not occur. He had been treated with fresh blood transfusions several times due to spontaneous bleeding from the nasal mucosa and digestive tract.
    In the present instane, he recieved dental managements for spontaneous oral bleeding. Transfusions of fresh platelet concentrates were carried out intentionally to elevate the count of circulating platelats by at least 50, 000/mm3 for one week after surgical procedures.
    In the present case, the idiopathic thrombocytopenia patient was reported who sought dental care and who already received splenectomy and prolonged corticosteroid therapy as repoted.It must be considered to produce anti-platelet antibody against fresh platelet concentrates as compared to antibody formations of regular blood transfusion.
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  • Kenji KAKUDO, Harumi ARAKI, Satoko OTAKE, Yoshinobu KUBO, Kozo MUSHIMO ...
    1986 Volume 32 Issue 7 Pages 1238-1243
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    This case report describes unusual dermoid and epidermal cysts in the oral region. This lesion was presented clinically as a coexistence case of a large dermoid cyst and four small epidermal cysts of the upper lip.A 4-year-old girl was seen on May 12, 1984, because of a diffuse swelling on the upper lip.On palpation, there were a large mass and two small masses which were discrete, movable and resilient in consistency. After exploratory extirpation of two small masses, a large mass was removed with another two smaller masses which were present during operation under general anesthesia. Histologically, the large mass was dermoid cyst and the four small masses were epidermal cysts.
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  • Haruhiko TERAI, Katsumi ONO, Yoshinobu NAKANO, Masashi SHIMAHARA
    1986 Volume 32 Issue 7 Pages 1244-1248
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Phleboliths in the maxillo-facial region are comparatively rare.
    In this paper, the case of 22-year-old man with multiple phleboliths in the submandibular region and cheek is presented with some discussion.
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  • Hirooki AOKI, Shigetaka YANAGISAWA, Keiichirou ONO, Megumi TAKAHASHI, ...
    1986 Volume 32 Issue 7 Pages 1249-1253
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Tumors which metastasized from other organs to oral regions had been relatively rarely reported with an occurance rate of about 1 per cent. In this instance, we reported a case of cancer which metastasized from the lung to the right maxilloalveolar region.
    Case; The patient was a fifty-year-old man. His chief complaint was the bleeding from 76 gum. The current status indicated formation of tumorous lesion with spontaneous pain and bleeding at the gum of right maxillary molar area. By radiographic examinations, we observed bone resorption at the right maxilla and the mass lesion at the upper left lung. The oral lesion was diagnosed as carcinoma by the biopsy specimen and suspected as metastasis from lung cancer. Although lung biopsy was done three times, histological examinations could not confirm an existence of carcinoma. As we thought oral carcinoma were metastasis, we treated the tumor with continuous infusion of 5 FU through the superficial temporal artery and per os administration of UFT. As a result, the alveolar maxillary tumor decreased to about the half its size before the treatment.But finally he died for cardiac insufficiency 3 weeks following the beginning of this therapy. The autopsy clarified the lung lesion to be large cell carcinoma and the oral tumor to be one of its metastatic lesions over the entire body.
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  • Kentaro MATSUMOTO, Masasumi MIYASAWA, Toshiaki IWASA, Masaru HORIKOSHI ...
    1986 Volume 32 Issue 7 Pages 1254-1259
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Although there have been various reports to improve visibility and safety in the surgical approach to the malar arch, post-operative problems such as sensory loss over the distribution of the auriculo-temporal region and undesirable cosmetic results are not uncommon. In 1979, Al-Kayat and Bramley reported on a modified preauricular approach to the malar arch and temporomandibular joint.This method is very safe and useful when operating in the temporomandibular joint region for various problems.
    From the period of February 1983 to August 1984, 5 cases of malar fractures in 4 males and in female patients of ages ranging from 25 to 48, were surgically treated using the Al-Kayat-Bramley method.In one case there were bilateral malar arch fractures and in the other four cases, threre were fractures at the suture lines and infraorbital foramen.Under general anesthesia, wiring of the fracture site was accomplished after open reduction.
    Good cosmetic results as well as the absence of trismus and facial nerve paralysis were obtained as a result of “open mouth” training which was performed two weeks after surgical intervention.
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  • Tsunenobu WAKAMATSU, Hiroshi MUKAI, Yuuichi TOMORI, Mitsutoshi IMAMURA ...
    1986 Volume 32 Issue 7 Pages 1260-1263
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Carcinoma in pleomorphic adenoma (CPA) is comparatively rare, and is reported to form from 2 to 10% of the pleomorphic adenomas of salivary glands. Recently, we experienced one CPA occurring in the right parotid gland of a 59-year-old man. The tumor was extirpated completely together with a portion of the superficial lobe of parotid gland. The prognosis is quite good and no recurrence is noted after 3 years follow up. Due to its high frequency of recurrence, further close observation is recommended.
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  • Tamotsu MIMURA, Masatsugu TAKUMA, Yutaka AZUMA, Masahiro NISNI, Etsuro ...
    1986 Volume 32 Issue 7 Pages 1264-1269
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    The bicortical screw fixation of the ascending ramus in sagittal split osteotomy presents many advantages, such as the short period of intermaxillary fixation, the diminution of relapse and so on. To secure successful results in the maneuver, the most important procedure is to settle the lateral fragment of ascending ramus in a precise position at the time of fixation. A facile technique was contrived and applied to eighteen cases of sagittal split.
    The method is as follows:
    1. Just prior to splitting, intermaxillary ligation is performed in order to fix the ascending ramus at the position of central occlusion.
    2. A V-shaped notch is engraved on the anterior edge of the ascending ramus at the level of the maxillary dental arch.
    3. A flexible metal frame for Schuchardt-Schiene is adjusted such that the terminal hook may fit to the notch and two or three hooks are plunged into the interdental spaces of the maxillary arch.Thus the position of the ramus is surveyed using the maxillary teeth as the landmarks.
    4.After splitting, intermaxillary ligation is performed again.The metal frame is adjusted to the maxillary arch.The notch of the lateral ascending ramus is fitted to the terminal hook. Thus the lateral ascending ramus is settled in the same position before splitting.
    5. Both fragments are fixed using metal or sapphire screws in the manner described elsewhere.
    The divergence in the position of the ascending ramus was analysed in seventeen cases. The goniometrical differences of the ascending ramus were estimated by superim posing lateral X-ray films obtained in pre-and postsurgical stage.
    The values were very small ranging from 1 degree to 10 degrees with an average of 3.9 degrees.Neither severe symptoms, such as longstanding pain and trismus, nor functional disturbances were observed clinically.
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  • Toshihide SUGIHARA, Yoshimitsu KAMEYAMA, Akira TATEISHI, Nagayoshi YAM ...
    1986 Volume 32 Issue 7 Pages 1270-1277
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    The odontogenic tumor, we experienced in the oral surgery is often carried clinically on the cystic lesions. We report on the experience of two cases of the tumor that is carried clinically on the cystic lesion, and postoperatively we made a definite determination histopathologically as odontogenic tumor.
    Case 1, the patient was a 48-year-old woman.Her lesion enucleated under the clinical diagnosis of the residual cyst of 6 region, but the histopathological examination revealed it to be the ameblastoma.
    Case 2, the patient was a 16-year-old girl.We diagnosed the globulomaxillary cyst of the left side, and studied the enucleated material histopathologically.The histopathological diagnosis was for adenomatoid odontogenic tumor.
    In the two cases, we mentioned the difficulty of the clinical diagnosis and the importance of the histopathological examination.
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  • Toru NAKAGAWA, Tadaaki KIRITA, Katsuhiro HORIUCHI, Yoshihiro NAKATANI, ...
    1986 Volume 32 Issue 7 Pages 1278-1282
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    A 21-year old man was reffered to the clinic with the chief complaint of the swelling on the upper lip.The specimen from the upper lip indicated malignant lymphoma histologicaly.Clinical course was very progressive and combination chemotherapy with VEMP was not so effective. The patient was dead at 4 months after onset.
    In this report, the clinical course is presented concomitant with autopsy findings.
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  • Akira KITAMURA, Tsugio INOKUCHI, Hiroyuki SUZUKI
    1986 Volume 32 Issue 7 Pages 1283-1292
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Surgical treatment of mandibular protrusion has been introduced by many surgeons. The method could be classified into the osteotomy at the ramus, condyle and body of the mandible.The patients were referred to our clinic for surgical treatment of abnormal occlusion. Sagittal splitting of the mandibular ramus was applied to four patients and one of them combined Le Fort I maxillary osteotomy with iliac bone graft. The pre and post-operative examination of the mandibular kinesiograph (MKG) devised by Jankelson was checked for each patient.The deviation of the mandible decreased after the operation and the inter cuspital and muscular contact position also come to close each other.
    The sagittal splitting of the mandibular ramus recovered the well occlusal position and showed the good results on the MKG examination.
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  • comparison of 1-hexylcarbamoy1-5-fluorouracil (HCFU) and 5-FU
    Nai-Rong Wu, Yasuichi MUNENAGA, Kazuaki TAKADA
    1986 Volume 32 Issue 7 Pages 1293-1298
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Using the guides of the inhibitory rate of isoproterenol-stimulated DNA synthesis of mouse parotid glands and the survival time of Ehrlich ascites bearing mice, a study was conducted to compare the combined effect of HCFU and X-ray irradiation to that of 5-FU and irradiation. The combined effect of HCFU given 2 hours after irradiation revealed a significant synergistic effect which was about twice effective as that of 5-FU and irradiation in both experiments.This indicated the superiority of HCFU in combination with X-ray irradiation.
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  • Hideo KUROKAWA, Takahiro KODAMA, Chiazin LIN, Keiko YASUMASU, Shoji TS ...
    1986 Volume 32 Issue 7 Pages 1299-1305
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Malignant lymphoma is a neoplasm arising from the lymph node and lymphoid tissues.This tumor occurs frequently in the head and neck, but it occurs rarely in the oral cavity.
    Recently, we experienced one case of malignant lymphoma arising from the gingiva of upper jaw in a 59 year-old man, and reported on it with some comments based on the existing literature.
    He was treated by intra-arterial infusion chemotherapy, radiotherapy and surgical excision.
    Histopathologically, a diffuse lymphoma of medium sized cell type was diagnosed based on LSG classification (Lymphoma-Study-Groupe, 1979).
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  • Minoru TAMURA, Susumu TAKEDA, Katsuhiko SIMOJO, Midori NAKAJIMA, Osamu ...
    1986 Volume 32 Issue 7 Pages 1306-1314
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Since Burkitt (1958) first descrived a kind of sarcomas in the jaws of children in equatorial Africa, the tumor was called Burkitt's tumor and many cases have been reported.
    A 44-year-old woman visited our hospital with a complaint of a sensory paresthesia of the ower lip and a painless swelling of the thyroid gland and the right mammary area.A lymphadenopathy was noted in only right submandibular region.
    In histopathologic examination of biopsy specimen from thyroid gland, a so-called starrysky pattern was conspicuously observed due to macrophages dispersed among neoplastic lymphoid cells.
    The diagnosis of Burkitt's tumor was made.Further investigations revealed that the malignant cells were B-cell phenotype, however Epstein-Ball virus-determined nuclear antigen (EBNA) was not found.
    Although the patient was treated with the combined chemotherapy (BACOP), she died on the 113th day of hospitalization and an autopsy was done.The metastasis of tumor was seen in thyroid, lung, liver, spleen, kidneys, ovaries, mammary glands, diaphragm, brain stem, spinal cord, meninges and in many bone marrows.
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  • Katsuhiko SHIMOJO, Susumu TAKEDA, Osamu SUNADA, Hiroshige KANAI, Akira ...
    1986 Volume 32 Issue 7 Pages 1315-1318
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Oral florid papillomatosis (OFP) was first described by Rock and Fisher in 1960.It is a relatively rare lesion and looks clinically like a leukoplakia or a malignant tumor.
    A 75-year-old woman visited our clinic with a complaint of white lesions existing on the left side margin of the tongue, the alveolar ridge of left lower molar region and the left buccal mucosa.
    The clinical and pathologic diagnosis of leukoplakia was made.The lesions were excised after the treatment for 13 months with Etretinate (orally, total dose of 3080mg), Pepleomycin (intravenously, 90mg) and Bleomycin (by ionophoresis, 90mg).However, a recurrence was obserbed on all excised areas 6 months later.
    Repeated pathologic examinations were carried out and finally the diagnosis of OFP was obtaind.10mg of Bleomycin (intramuscularly) was administered weekly for 6 weeks.The treatment was very effective and a small lesion remaind on the buccal area.The patient has been followed-up with a treatment of repeated cryotherapy.
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  • SUSUMU TAKEDA, Osamu SUNADA, Mikito YAJIMA, Shunichi MINEMURA, Tadashi ...
    1986 Volume 32 Issue 7 Pages 1319-1322
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    In order to close a large oroantral fistula with osseous defect in a 74 year old man, a palatal flap with alveoli dentales of the maxilla was utilized and the good results were obtained with a complete closure of the fistula and adequate stability of the dental prosthesis. No disorder occurred after the surgery.Since it is very difficult to get the alveolar bone without injuring the radix dentis, this method is indicated only for edentulous patients.This compound flap is supplied of the A.palatina major.
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  • Keiichiro ONO, Shigetaka YANAGISAWA, Hirooki AOKI, Shoji KODAMA, Rinta ...
    1986 Volume 32 Issue 7 Pages 1323-1327
    Published: July 20, 1986
    Released on J-STAGE: July 25, 2011
    JOURNAL FREE ACCESS
    Branchiogenic carcinoma is a rare malignant tumor arising from the remnant of the branchial epithelium or the branchial cyst.We have experienced and treated a patient with branchiogenic carcinoma, the outline of which we report here.
    Patient: A 69-year-old female, visited our hospital on 21 May 1984, and complained of a swelling in the right neck and submandibular regions, where a thumb-haadsized tumor was found with palpation at the later region. On 20 June, the tumor was resected with a purpose of biopsy under general anesthesia. A histological examination of the mass clarified an existence of the squamous cell carcinoma with a cystic lesion. Lymphoid tissues were found under the cyst wall. The block of S.C.C.was considered as protruded part from the cyst wall. Several clinical examinations were performed, detecting a metastasis to the other organs, through which we could not find any other tumors. A diagnosis of branchiogenic carcinoma was finally decided upon. On 4 July, a radical neck dissection was done on suspection of upper neck metastasis, where upon a farther histological examination of the specimen confirmed a lymph node metastasis. Then postoperative irradiation and chemotherapy were performed in combination. The patient has survived now for over one and a half years since these treatments without any recurrence of the tumor.
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