Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Volume 48, Issue 8
Displaying 1-15 of 15 articles from this issue
  • Tomoari KURIYAMA, Hakuzo ARAKI, Sumie TAKAI, Kaori IWAHARA, Yukiko KAR ...
    2002 Volume 48 Issue 8 Pages 379-385
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Orofacial odontogenic infections are usually treated with a β-lactam antibiotic. Most majorpathogens are susceptible to β-lactam antibiotics, although Prevotella species have been reported to produce β-lactamase and be resistant to β-lactam antibiotics. The purpose of this study was to evaluate β-lactamase production and antimicrobial susceptibility to 12 β-lactam antibiotics of Prevotella speciesisolated from 128 orofacial odontogenic infections. We confirmed that only Prevotella species were β-lactamasepositive in most isolates. Overall, 43.7% of pigmented Prevotella and 34.8% of nonpigmented Prevotella were positive for β-lactamase. The β-lactamase-positive strains were resistant to most of theantibiotics tested. However, piperacillin/tazobactam, cefmetazole, and faropenem showed antimicrobialactivity against these strains. In conclusion, this study shows the importance of β-lactamase-producing Prevotella strains in odontogenic infections and the need for appropriate choice of antibiotic.
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  • Akiyoshi GOTOH, Mutsuhiko MURAI, Takayuki OHSAWA, Kazuma MASUMOTO, Mic ...
    2002 Volume 48 Issue 8 Pages 386-389
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    We designed chemotherapeutic regimens combining docetaxel (TXT) and TPP (THP-ADM, CDDP, PEP) or TXT and TPF (THP-ADM, CDDP, 5 FU) for the treatment of oral squamous cell carcinomasand evaluated their primary effects. Nine patients were treated. Forty milligrams of TXT per squaremeter was administered on day 2 intravenously. The patients were 6 men and 2 women 43 to 55 years ofage (mean age, 50) years at presentation. The primary site was the tongue in 6 patients and themandibular gingiva in 2. TNM classification was T 2 in 4 patients, T 3 in 2, T 4 in 2, and N 2 b in 2.All cases were M O.
    The response rate with a combination of TXT and TPP was 100%(CR 50%, PR 50%) and that with acombination of TXT and TPF was also 100%(CR 50%, PR 50%). Among the 5 patients who additionallyreceived surgery, the Ohboshi & Shimozato classification was II B in 3 and N B in 2.
    The main side effects were febrile neutropenia, anorexia, and stomatitis, but there was no effect on subsequenttreatment.
    We conclude that our chemotherapeutic regimens are effective against oral squamous cell carcinoma.
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  • Tsutomu KOITABASHI, Hideki KON, Jiro NAKAE, Satoshi TAKADA, Takashi OH ...
    2002 Volume 48 Issue 8 Pages 390-393
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Malignant myoepithelioma is an uncommon malignant tumor newly adopted as a separate entityin the revised WHO classification of salivary gland tumors (1991).
    We report a case of malignant myoepithelioma with destruction of maxillary bone. A 75-year-oldwoman was referred to our hospital because of swelling of the right side of the palate. Computed.tomography showed a tumor with destruction of the right side of the maxilla. Biopsy suggested a malignantsalivary gland tumor. We removed the tumor under general anesthesia. Histologically, the tumor consistedmainly of solid sheets of ovoid cells and plasmacytoid cells with clear cytoplasm. The histopathologicdiagnosis was malignant myoepithelioma. The patient's postoperative course has been good, with noevidence of recurrence as of about 3 years after operation.
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  • Yuzo MIZUGAKI, Yoshikazu HAYATSU, Takanori ISHIMARU, Rie KUSUMOTO, Mas ...
    2002 Volume 48 Issue 8 Pages 394-397
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Lethal midline granuloma is a T/natural killer cell lymphoma characterized by progressive ulcerationand necrosis of the nasal cavity or pharynx along the midline facial tissues. A case of lethalmidline granuloma in the palate of a 63-year-old woman is reported. The patient had a low-grade fever anda large ulcer with hemorrhage in the palate. Clinically, a malignant tumor was initially suspected becauseof rapid progressive ulceration, but inflammatory disease was pathologically diagnosed on examination ofa tissue specimen stained with hematoxylin and eosin. The definite diagnosis was made by in situ hybridizationwith Epstein-Barr virus RNA (EBV encoded small RNA- 1: EBER 1)-specific oligonucleotideprobes, which showed positive signals in small lymphocytes. The patient's condition became critical becauseof frequent hemorrhage, and she soon died.
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  • Hiroto ITOH, Mikio KUSAMA, Taku TSUKAHARA, Yoshinori JINBU, Yoko AKASA ...
    2002 Volume 48 Issue 8 Pages 398-400
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    We report a very rare case of basal cell adenocarcinoma arising in the left parotid gland. The patientwas 51-year-old man who had noticed swelling of the left parotid gland 1 month earlier. Since he felt, pain in the region, he consulted our university hospital. A parotid gland tumor was diagnosed and the superficiallobe and a part of the deep lobe near the tumor were surgically resected.
    The histopathological diagnosis was basal cell adenocarcinoma. There has been no recurrence for 7months after operation.
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  • Shinichi NOZAKI, Mayumi SHIMADA, Akira TANAKA, Koichiro UEKI, Kiyomasa ...
    2002 Volume 48 Issue 8 Pages 401-403
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Odontogenic fibroma is a rare benign neoplasm that was categorized under the subheading of tumorsconsisting of odontogenic ectomesenchyme, with or without odontogenic epithelium, by the World Health Organization in 1992.
    A 42-year-old woman was referred to the Department of Oral and Maxillofacial Surgery, Kanazawa University Hospital for evaluation of a lesion that was present in the right molar region of the maxilla for 7 years. The lesion was a 20×20-mm slightly radiopaque area with a groove formed by contact with theadjacent bone and was excised along with the first molar. Eight years have elapsed since excision, with noevidence of recurrence.
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  • a case report with immunohistochemical studies
    Daiji TOMITA, Yuuji WARITA, Hiroyuki KANEKO, Hiroyuki ABE
    2002 Volume 48 Issue 8 Pages 404-407
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Verruciform xanthoma (VX) is a rare lesion of the oral cavity, first described by Shafer in 1971.Most cases of VX occur in the gingiva. VX arising in the lip is extremely rare. We report a case of VX arisingin the lower lip and discuss its histogenesis.
    A 69-year-old woman consulted our hospital because of a lower lip mass on April 27, 2000. Intraoral examinationshowed a yellowish tumorous lesion with a rough surface, measuring 22×14mm, on the mucosalsurface of the lower lip. A biopsy was performed, and the diagnosis was verruciform xanthoma. Based onthis diagnosis, the tumor was excised under local anesthesia on May 31.
    Histopathologically, the tumor consisted of stratified squamous epithelium with parakeratosis andshowed elongated rete ridges. Between and under the rete ridges, aggregation of foam cells was observed.These foam cells were immunohistochemically positive for CD-68 and lysozyme, which indicated that thecells were histiocytes of the monocyte-macrophage system.
    The patient has had no local recurrence as of 1 year 6 months postoperatively.
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  • Yusuke NAKAJIMA, Megumi KANEKO, Ichiro SETO, Wataru ISHIGURO, Yutaka M ...
    2002 Volume 48 Issue 8 Pages 408-411
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    A rare case of lymphoepithelial cyst arising in the parotid gland is reported. Lymphoepithelialcyst usually occurs in the soft tissue of the lateral neck region. Thus, it is called “lateral cervical cyst.” Itis also known as “branchial cyst, ” because it is believed to arise from epithelial remnants of the branchialclefts. A 71-year-old man was referred to us because of a painless swelling of the right infra-auricular region. It was elastic soft, non-tender, and slightly movable. A preoperative diagnosis of benign cystic lesionarising in the parotid gland was made on MRI and sialo-MRI. The lesion was located in the tail of thegland and was removed without damaging the facial nerve. Histopathological examination of the surgicalspecimen revealed a lymphoepithelial cyst in the parotid gland. Tubular structures resembling salivarygland ducts were seen in the cyst wall. The cystic contents showed high levels of amylase and gamma-GTPactivity, indicating that the cyst arose from epithelium of the parotid gland entrapped in a lymph node.The lesion was treated successfully by simple removal. Lobectomy or partial resection of the parotid glandwas not needed. There has been no sign of recurrence as of 15 months postoperatively.
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  • Tohru TSURUMI, Hiroaki KUJIRAOKA, Masaharu TSUTSUMI, Ryuji NAMBA, Momo ...
    2002 Volume 48 Issue 8 Pages 412-415
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    A rare case of an intramuscular hemangioma of the temporal muscle is reported.
    A 34-year-old woman presented with swelling and spontaneous pain in the right temple. On MRI, T 1-weighted images showed a low-signal-intensity lesion. T2-weighted images and T 1-Gd weighted images toeliminate the effect of fat showed a high-signal-intensity lesion. The lesion measured 34×31×8 mm. Thesefindings suggested a diagnosis of hemangioma. The tumor was totally excised, and histological examinationconfirmed the diagnosis of an intramusclar, cavernous type of hemangioma. One year after operation, the cosmetic result is excellent, and the patient remains free of symptoms and recurrence.
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  • Kazuhide NISHIHARA, Tamotsu MIMURA, Etsuro NOZOE, Yasunori NAKAMURA, H ...
    2002 Volume 48 Issue 8 Pages 416-419
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Goldenhar syndrome, characterized by the triad of epibulbar dermoids, auricular anomalies, andvertebral deformities, is a relatively rare congenital anomaly estimated to occur every 3, 000 to 5, 000 births. Cleft lip, cleft palate, or both occurs in 2% to 25% of cases. A case of Goldenhar syndrome withunilateral cleft lip and palate is reported.
    A 3-month-old boy was referred by a pediatrician to our department for treatment of dyspnea and cleftlip and palate.
    He had multiple malformations, including complete unilateral cleft lip and palate, bilateral epibulbarlipodermoids, left keratoleukoma, obstruction of the right meatus and stenosis of the left meatus, accessorytragus, laryngeal malacosis, mandibular micrognathia, and hypoplasia of the right side of thetongue. No vertebral deformity was present. The diagnosis was Goldenhar syndrome of incomplete type.
    The patient had severe dyspnea due to mandibular micrognathia and laryngeal malacosis. Tracheotomywas performed by the department of pediatric surgery 3 months after birth. After the procedure, dyspneaimproved, and body weight increased. Cheiloplasty was carried out at our clinic at 7 months.
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  • Fumihiko SATO, Noritaka TSUNODA, Shintaro SUZUKI
    2002 Volume 48 Issue 8 Pages 420-422
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    We report and briefly discuss an atypical case of mucous retention cyst arising in the hardpatient, a 21-year-old woman, had noticed swelling in the left side of the hard palate.Thewas dark red, resenbling a hematoma or hemangioma.When we excised the lesion underanesthesia, we found bone resorption of the hard palate.The clinical diagnosis was hemangiomaclinical and operative findings, but the pathological diagnosis was mucous retention cyst.
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  • Akira TATEISHI, Yuji AMANO, Takayuki AIDA, Jinichi FUKUDA
    2002 Volume 48 Issue 8 Pages 423-426
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    A case of non-clostridial gas gangrene with sepsis in the maxillofacial region and neck caused byodontogenic infection is reported.A 74-year-old woman consulted our department because of painful swellingof the head and neck region.She had been treated for depression for about 20 years.Her general conditionwas classified as I-2 coma according to the Japan coma scale.Blood examination revealedleukocytosis, hepatopathy, nephropathy, hypoalbuminemia, and hyperglycemia.A computed tomographicscan showed gas accumulation with abscess formation in the temporal, buccal, submandibular, and cervicalregions.Administration of antibiotics (PAPM/BP) and gamma-globulin was followed by emergencysurgical drainage under general anesthesia. Microbiological examinations revealed Streptococcus pneumoniae in the abscess and Peptococcus asaccharolyticus in venous blood on the 1st disease day. Aftertreatment, the swelling disappeared and the results of blood tests became normal.However, a secondmicrobiological examination of venous blood also revealed Peptococcus asaccharolyticus on the 9 th diseaseday. Antibiotics (CLDM) were given from the 17th to 20th disease days.Hyperglycemia was controlledby insulin.She was discharged on the 53rd disease day.
    Rapid diagnosis by computed tomography, rapid surgical drainage, appropriate chemotherapy, and examinationsof blood cultures and for DIC are required to save patients'lives.
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  • Takashi KAKIZAWA, Takashi MATSUI, Masayuki TAKANO, Yohko YOKOYAMA, Tam ...
    2002 Volume 48 Issue 8 Pages 427-430
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    We describe a case of oral trichomoniasis associated with poor healing of an extraction cavityin the maxilla. The patient was a 44-year-old man who visited our hospital becauseof poor healing of anextraction cavity. Examination confirmed discharge of pus from the cavity and the presence of agranulation-like mass. Radiography revealed prominent bone destruction surroundingthe extraction cavity, and cytological examination confirmed the presence of Trichomonas tenax. A working diagnosis of Trichomonas tenax induced granulomatous inflammation was made. After oral administration of anantitrichomal drug, the mass was excised, and the extraction cavity underwent curettage. Progress afterresection was satisfactory, and the extraction cavity healed uneventfully. Although Trichomonas tenax isgenerally innocuous, our findings suggest that it acted as a pathogen in the present case.
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  • Yuka KOJIMA, Mltsuo NISHIDA, Yoshihiko YOKOE, Koji SUGA, Kenichiro MUR ...
    2002 Volume 48 Issue 8 Pages 431-434
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    A 25-year-old Japanese woman was referred to us because of open bite with micrognathia. Shehad undergone an unsuccessful sagittal splinting ramus osteotomy (SSRO) for correction of open bite, which developed after surgery for condylar fractures at another hospital.
    Radiographs revealed extensive resorption of both mandibular condyles. The coronoid processes wereelongated and functioned as the temporomandibular joint. The resorption was attributed to vascularischemia after open reduction of the condylar fractures and to MRSA infection after orthognathic surgery.
    In our department, SSRO was performed again to correct the retromandibular region after successfulanti-inflammatory treatment. Functional articulation with the coronoid process andcosmetic improvementwas obtained postoperatively.
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  • Hiromitsu NABESHIMA, Edegar Grageda, Jamie Lozada, Anil P. Punjabi, Ko ...
    2002 Volume 48 Issue 8 Pages 435-438
    Published: August 20, 2002
    Released on J-STAGE: April 22, 2011
    JOURNAL FREE ACCESS
    Autogenous cancellous bone grafting is a common procedure in implant surgery. A satisfactoryamount of autogenous cancellous bone graft can be obtained to reconstruct a severely atrophic maxilla.The most commonly used site for harvesting sufficient bone is the extraoral region, i. e., the iliac crest;however, open harvesting in this area usually results in many postoperative complications. To minimizethese complications, tibial bone is used as an alternative source of sufficient bone. Tibial bone can be harvestedwith the patient under local anesthesia and intravenous sedation, without general anesthesia. A curetteis used to harvest the graft at the lateral slope of the tibial tuberosity, there by obtaining 5g ofautogenous bone. Advantages of this technique include a shorter operation time and less blood loss thanconventional procedures. No major postoperative complications occurred with this technique.
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