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Volume 61, Issue 7
Displaying 1-7 of 7 articles from this issue
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Preface
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[in Japanese]2015 Volume 61 Issue 7 Pages 359
Published: July 20, 2015
Released on J-STAGE: November 09, 2015
JOURNAL FREE ACCESSDownload PDF (835K)
Invited review article
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Satoshi IMAZATO2015 Volume 61 Issue 7 Pages 360-362
Published: July 20, 2015
Released on J-STAGE: November 09, 2015
JOURNAL FREE ACCESSRecently, Mineral Trioxide Aggregate （MTA） categorized as calcium silicate cements has been frequently used for root-end filling. MTA is advantageous in sealing of root and hard-tissue formation, and many clinical studies which reported successful results for apicoectomy using MTA are available. 4-META/MMA adhesive resins, which show superior bonding ability to dentin, are also promising materials for root-end filling. However, in addition to durable sealing, abilities to control infection or promote tissue regeneration are important for ideal root filling materials. Therefore, development of new technologies to achieve adhesive resins for root-end filling with antibacterial effects or FGF-2-releasing property is in progress.View full abstractDownload PDF (765K)
Case reports
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Shinji UEJIMA, Choichiro SHINMURA, Shintaro NISHINO, Yoshiro KOMA, Mas ...2015 Volume 61 Issue 7 Pages 363-367
Published: July 20, 2015
Released on J-STAGE: November 09, 2015
JOURNAL FREE ACCESSBasal cell adenocarcinoma （BCAC） is a rare tumor of the salivary gland and commonly arises in the parotid gland. It very rarely occurs in a minor salivary gland of the palate. We report the case of an 81-year-old Japanese woman with BCAC of the palatal minor salivary gland. Computed tomography and magnetic resonance imaging showed a mass （60 × 50 × 35mm） arising in the left side of the palate. The mass extended beyond the midline and invaded the maxillary sinus and pterygoid process. A biopsy was performed, and BCAC was diagnosed. Radiotherapy was administered at 2 Gy/fraction/day, and the total dose delivered to the primary tumor was 70 Gy. The lesion clinically shrank after radiotherapy. There has been no evidence of growth of the primary tumor or distant metastasis as of 24 months after radiotherapy.View full abstractDownload PDF (1069K) -
Michihide KONO, Masato WATANABE, Hayato HAMADA, Ko FUJIKAWA, Takafumi ...2015 Volume 61 Issue 7 Pages 368-373
Published: July 20, 2015
Released on J-STAGE: November 09, 2015
JOURNAL FREE ACCESSDiffuse sclerosing osteomyelitis （DSO） of the mandible is known to be treatment-refractory osteomyelitis. DSO usually cannot be successfully treated by antibiotics, and there are no established treatments. We describe a case of DSO of the mandible in a juvenile patient that was successfully treated by intravenous pamidronate. The patient was a 14-year-old girl who was referred to our department in April 2008 because of left mandibular pain and swelling. Computerized tomography showed cortical bone thickening with lytic and sclerotic lesions in the mandibular ramus and mandibular angle. The histological findings of a biopsy specimen led to the diagnosis of osteomyelitis, but the results of bacteriological examination of bone marrow were negative. We diagnosed DSO, and roxithromycin was administered orally for 11 months. However, the symptoms did not improve. In March 2009, we performed decortication of the affected mandible with the patient under general anesthesia. However, the symptoms recurred 2 months after surgery. In July 2010, we intravenously administered pamidronate, with the approval of the Tokyo Medical University Hospital institutional review board. The patient’s symptoms improved the next day. Approximately 4 years after the treatment, the symptoms have not recurred, and no lesions have been detected on radiographic imaging.View full abstractDownload PDF (1055K) -
Akio SHIBATA, Junichiro MACHIDA, Seishi YAMAGUCHI, Tadashi TATEMATSU, ...2015 Volume 61 Issue 7 Pages 374-378
Published: July 20, 2015
Released on J-STAGE: November 09, 2015
JOURNAL FREE ACCESSMelnick-Needles syndrome （MNS） is a rare congenital X-linked syndrome associated with severe bone dysplasia, characterized by anomalous ossification, patterning of the axial and appendicular skeleton, and characteristic faces （exophthalmos, full cheeks, micrognathia, and malalignment of teeth）. MNS is considered an otopalatodigital （OPD） spectrum disorder owing to overlapping clinical phenotypes. Recently, the filamin A （FLNA） gene has been reported to be a responsible gene for OPD spectrum disorders, and the region of mutations correlates with clinical phenotypes. We report a case of MNS that was diagnosed on the basis of clinical symptoms and genetic studies. An 8-year-old girl was referred to our clinic for detailed evaluation of maxillofacial skeletal abnormality. She had systematic bone dysplasia, short stature, and a characteristic facial appearance caused by micrognathia. On the basis of these clinical findings, She was suspected to have MNS. Furthermore, we definitively diagnosed MNS by demonstrating the presence of a heterozygous recurrent mutation （c.3596C>T, amino acid substitution: S1199L）.View full abstractDownload PDF (981K) -
Sawako NODA, Takashi I, Mayumi UMEBAYASHI, Yoshinori SUMITA, Shuichi F ...2015 Volume 61 Issue 7 Pages 379-383
Published: July 20, 2015
Released on J-STAGE: November 09, 2015
JOURNAL FREE ACCESSKimura’s disease is a relatively rare benign disease of unknown etiology, associated with a painless mass usually arising in the subcutaneous soft tissue of the head and neck. We report a case suspected as the initial lesion of Kimura’s disease arising in buccal region of a 31-year-old man, who admitted to our hospital because of a painless mass in the left cheek. The mass was elastic soft with a clear margin under the buccal mucosa. T2-weighted magnetic resonance imaging showed a slightly low density mass in the buccal fat. There were no abnormal findings on peripheral blood examinations. The lesion was surgically excised with the patient under general anesthesia for the clinical diagnosis of a benign tumor. Histopathological examination of the tumor demonstrated many lymphoid follicles in the adipose tissue. Some of germinal centers in the follicles showed IgE deposition. Interfollicular fibrosis was present, and the adipose tissue was infiltrated by eosinophils as well as lymphocytes, plasma cells, and mast cells. These findings suggested an early lesion of Kimura’s disease. The peripheral blood examination showed that the number of eosinophils had increased to the upper limit of normal. The postoperative course was uneventful, and there has been no recurrence as of more than 1 year after operation without any additional treatment, but further follow-up is necessary.View full abstractDownload PDF (1112K) -
Kohei MATSUDA, Toyonori SUZUKI, Yoshinori KOBORI, Chikara MURAKI, Mari ...2015 Volume 61 Issue 7 Pages 384-389
Published: July 20, 2015
Released on J-STAGE: November 09, 2015
JOURNAL FREE ACCESSPycnodysostosis, first described by Maroteaux and Lamy in 1962, is a rare autosomal recessive disease characterized by generalized diffuse bone sclerosing, short stature, and bone fragility, occurring frequently in association with skeletal dysplasia. Complications of pycnodysostosis such as intractable maxillary and mandibular osteomyelitis are common and appear in various forms. We present a case of mandibular osteomyelitis in a patient with pycnodysostosis who responded successfully to 7 years of conservative treatment. A 48-year-old woman who was previously given a diagnosis of pycnodysostosis was referred to our hospital because of continuous swelling and pain around the mandibular left first molar. Osteomyelitis gradually progressed after removal of the first molar. After a long follow-up period, during which the patient received local irrigation and low-dose antibiotic therapy, sequestration occurred. The lesion was cured completely by additional application of hyperbaric oxygen therapy （20 sessions）. Even after 10 months of follow up, there has been no recurrence of inflammation.View full abstractDownload PDF (990K)
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