Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Volume 55, Issue 9
Displaying 1-7 of 7 articles from this issue
Preface
Invited review article
  • Hiromasa YOSHIE, Kazuhiro OKUDA, Tomoyuki KAWASE
    2009 Volume 55 Issue 9 Pages 432-439
    Published: September 25, 2009
    Released on J-STAGE: August 28, 2012
    JOURNAL FREE ACCESS
    Based on recent advances in tissue engineering, we have developed three individual therapeuticmethodologies for regeneration of periodontal defects. (1) Human cultured gingival epithelial cell sheets couldbe applied as a promising graft “material" to treatment of chronic desquamative gingivitis. (2) Cultured gingivaldermal substitute could contribute to accelerated recovery of vertical and horizontal gingival recession. (3)Cultured periosteal cell sheets, which are demonstrated to express osteogenic activity in vitro and in vivo animalstudies, could regenerate alveolar bone defects in combination with platelet-rich plasma and porous hydroxapatiteparticles. Finally, current and next-generation technology in tissue engineering and periodontal regenerative medicineshould be discussed.
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Original article
  • Naoki TANIIKE, Toshihiko TAKENOBU, Takeya YAMADA, Atsushi TAKAHASHI, K ...
    2009 Volume 55 Issue 9 Pages 440-447
    Published: September 25, 2009
    Released on J-STAGE: August 28, 2012
    JOURNAL FREE ACCESS
    We successfully used an endoscope to assist in the repair of mandibular condylar fractures in 12patients from August 2006 through October 2007. Their ages ranged from 16 to 68 years, with an average of 35years. All patients presented with unilateral condylar fractures. Seven of the 12 patients additionally had mandibularfractures.
    A 4.0-mm, 30-degree angled endoscope was introduced to visualize the fracture site by means of an intraoralincision over the ascending ramus. A 2.0-mm titanium miniplate and screws were used to stabilize the fracture sitewith the help of a percutaneous trocar. The use of an angled endoscope provided a good view of the fracture site,permitting precise anatomical reduction.
    All patients had a stable occlusion in the postoperative period, and anatomic alignment of the condyle was confirmedradiographically. There was no persistent facial palsy.
    The benefits of using this endoscopically assisted technique include not only the provision of better visualizationand precise anatomic alignment of bony segments, but also the avoidance of facial nerve injuries and largefacial scars.
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Case report
  • Sachiko KIMIZUKA, Yoshiyuki OKAMOTO, Shinjiro AOKI, Susumu OMURA
    2009 Volume 55 Issue 9 Pages 448-452
    Published: September 20, 2009
    Released on J-STAGE: August 28, 2012
    JOURNAL FREE ACCESS
    Sarcoidosis is a systemic disease of unknown etiology characterized pathologically by noncaseatingepithelioid cell granulomas affecting any organ. It is often associated with bilateral hilar lymphadenopathy, pulmonaryinfiltration, and skin or eye lesions. We report a case of sarcoidosis with submandibular lymphadenopathy.
    The patient was a 28-year-old woman who presented with a left submandibular painless nodule. Magnetic resonanceimaging(MRI)revealed a submandibular mass with low intensity on T-1 weighted images and high intensityon T-2 weighted images. Under general anesthesia, resection of the lesion was performed. Histologically thespecimen consisted of numerous noncaseating epithelioid cell granulomas. The histological diagnosis was sarcoidosis,and additional examinations were conducted. Ga-67 scintigraphy bilaterally showed increased uptake inthe lacrimal glands, parotid glands, and hilar lymp nodes. Bilateral hilar lymphadenopathy was confirmed on thoracicCT scanning, and bilateral swelling of the parotid gland was confirmed on MRI. The results of the tuberculinskin test were negative, and the serum levels of angiotensin-converting enzymes and γ-globulin were increased.These findings supported the histological diagnosis. Because the patient was asymptomatic, only careful follow-upwas continued, without treatment. During 24 months of follow-up, bilateral swelling of the parotid gland graduallydecreased, and abnormal uptake of Ga-67 disappeared in all lesions.
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  • Tomotake MASUDA, Noriaki TANAKA, Seiji IIDA, Natsuko SAWAI, Takafumi O ...
    2009 Volume 55 Issue 9 Pages 453-457
    Published: September 20, 2009
    Released on J-STAGE: August 28, 2012
    JOURNAL FREE ACCESS
    Epulis osteoplastica is a rare disease. We report a case of giant epulis osteoplastica containing a largesequestrum. A 63-year-old man was referred to our clinic because of a painless swelling on the left mandibularalveolus. Intraoral examination revealed an elastic hard tumor with a normal surface in the left lower molar region.Radiographic examination showed a large radiopaque mass separate from mandibular bone. Gingival tumor excisionwas performed with the patient under general anesthesia. The excised specimen measured 50 X 38 X 28mm and contained the bony mass. Histopathologically, the lesion was diagnosed as epulis osteoplastica with asequestrum. The patient was followed up for 4 years after the operation, without any recurrence.
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  • Yoshitaka TANIGUCHI, Kazuhiko URABE, Shinichiro HIRAOKA, Masaaki KIMAT ...
    2009 Volume 55 Issue 9 Pages 458-462
    Published: September 20, 2009
    Released on J-STAGE: August 28, 2012
    JOURNAL FREE ACCESS
    Schwannoma is a benign tumor derived from the Schwann cells. This tumor is relatively rare in the oraland maxillofacial region, and schwannoma in the pterygomandibular space is extremely rare. This reportdescribes a case of schwannoma in the pterygomandibular space. A 58-year-old woman presented with swellingand discomfort of the lateral oropharynx on the right side. Magnet resonance imaging showed a T2 high-signaldensitymass, measuring 35 mm × 30 mm, in the pterygomandibular space. We performed a biopsy under generalanesthesia. Histopathologically, the mass was diagnosed as a schwannoma.
    The tumor was surgically removed under general anesthesia. There was no evidence of recurrence 2 years postoperatively.
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  • Tomoki SUMIDA, Yumi KATO, Tomohide YOSHIMURA, Ryuichi MURASE, Koh-ichi ...
    2009 Volume 55 Issue 9 Pages 463-466
    Published: September 25, 2009
    Released on J-STAGE: August 28, 2012
    JOURNAL FREE ACCESS
    Methotrexate (MTX) has been proven to be effective for the treatment of rheumatoid arthritis (RA)and is believed to be nononcogenic when a low weekly dose is administered to patients with RA. However, wereport the case of a 71-year-old man with RA who was treated for 11 years with MTX and developed B cell non-Hodgkin's lymphoma (BNHL) in the oral cavity. The tumor was localized in the right maxilla extranodally.Microscopic examination of a biopsy specimen revealed a non-epithelial tumor pattern and showed BNHL inwhich large cells with pleomorphic nuclei invaded the muscle tissue. These large cells tested strongly positive forEpstein-Barr virus encoded small RNAs-in situ hybridization (EBER-ISH) and CD20 antibody. We immediatelystopped MTX administration; however, only minimal shrinkage of the tumor was observed. Therefore, we performedantibody treatment with rituximab. After chemotherapy, complete remission was achieved. To date, thepatient is healthy, with no evidence of tumor recurrence during 32 months of follow-up. The development of anextranodal lymphoma in the oral cavity in a patient with RA who received MTX has not been reported previously.Therefore, this case is considered extremely rare.
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