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Volume 50, Issue 7
Displaying 1-8 of 8 articles from this issue
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Daisuke UCHIDA, Tetsuya TAMATANI, Yoshifumi TOMIZUKA, Go OHE, Hideo YO ...2004 Volume 50 Issue 7 Pages 415-421
Published: July 20, 2004
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSPycnodysostosis is an uncommon, autosomal recessive skeletal dysplasia characterized by osteosclerosis, bone fragility, osteomyelitis of the mandible, short stature, and actroosteolysis. Recently, we encountered a patient with pycnodysostosis associated with persistent osteomyelitis of the mandible. We report the treatment and mutation analysis of this patient. A 57-year-old man visited our clinic because of pus discharge from the mandibular skin. He had a history of three tibial fractures and had been given a diagnosis of pycnodysostosis at the department of orthopedic surgery. Resolution, sequesterectomy, and excision of the external fistula were performed for a diagnosis of osteomyelitis of the mandible with an external fistula. Subsequently, recrudescence occurred three times, but the patient responded to treatment with azithromycin (AZM). Mutations in the gene encoding cathepsin K, a cysteine protease localized exclusively in osteoclasts, have been recently demonstrated to be responsible for pycnodysostosis. In this study, we performed rapid mutation analysis by amplifying cathepsin K open reading frame (ORF) by reverse transcriptase-polymerase chain reaction (RT PCR), using highly sensitive DNA polymerase and total RNA derived from hematopoietic cells. We found that mutation of cathepsin K gene products converted leucine from proline at the position of the 9th amino acid (codon 9leu-pro; Pro; L9P) These results indicated that persistent osteomyelitis of the mandible in this patient resulted in a major symptom characterized by pycnodysostosis. Moreover, our experimental approach is rapid and sensitive and may be useful for the mutation analysis of diverse diseases.View full abstractDownload PDF (3625K) -
Yasumitsu KODAMA, Jun-ichi FUKUDA, Hajime FUJITA, Hisao AJIMA, Kazuhir ...2004 Volume 50 Issue 7 Pages 422-425
Published: July 20, 2004
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSWe report a case of mandibular asymmetry suggested to have delayed growth as a late effect after orthodontic surgery.
Postoperative delayed growth often causes occlusal instability and a poor profile as a late effect. It is difficult to predict such changes because the causes differ from those of general relapse, and development is accidental. Although occlusal instability caused by delayed growth after orthodontic surgery is rare and poorly understood, investigating the details of such changes is of great value for postoperative orthodontics or planning reoperation.
Our findings suggested that changes in mandibular elongation caused by delayed growth differed between the right and left sides. The differences were greatest at the ramus and condyle on the displaced side, showing vertical elongation.
In patients undergoing orthodontic surgery for mandibular asymmetry, the possibility of puberal growth spurts should be considered and patients should be followed up carefully since asymmetry can recur.View full abstractDownload PDF (2249K) -
Sachiko MUNEMOTO, Yasuyuki SHIBUYA, Shigetada MURAOKA, Shinshou RI, Ma ...2004 Volume 50 Issue 7 Pages 426-429
Published: July 20, 2004
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSTwo cases of subcutaneous and mediastinal emphysema caused by removal of lower third molars with an air turbine are reported. Case 1: A 25-year-old woman was referred to our hospital immediately after removal of a left lower third molar with an air turbine. She complained of bilateral swelling of the cheeks and submandibular regions and slight dyspnea. A computed tomographic (CT) scan revealed aerodermectasia from the left submandibular region to the right temporal region and bilateral cervical region. The CT scan also showed mediastinal emphysema. The patient was hospitalized and given a drip intravenous infusion of antibiotics for 3 days. Recovery was uneventful. Case 2: A 32-year-old woman complained of bilateral swelling of the cheeks at the time of extraction of the left lower third molar with an air turbine. She was referred to our hospital for further evaluation. A CT scan revealed aerodermectasia from the left submandibular region to the left temporal and bilateral cervical regions, associated with mediastinal emphysema. Antibiotics were administered by intravenous drip infusion for 3 days, and she recovered.View full abstractDownload PDF (2032K) -
Tsubura SUZUKI, Hideaki SAKASHITA, Akira EDA, Noriyuki SUKA, Seiji SUZ ...2004 Volume 50 Issue 7 Pages 430-433
Published: July 20, 2004
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSThyroglossal duct cyst is thought to originate from the epithelial remnant of the thyroglossal duct. A cyst usually arises between the cecal foramen of the tongue and the thyroid gland. We report a rare case occurring in the tongue. A 61-year-old man was referred to the Department of Dentistry and Oral Surgery, Hospital because of swelling of the tongue. The mass of the tongue, 18×20mm, was elastic soft and purplish red. Magnetic resonance imaging indicated the presence of a cystic lesion. The lesion was enucleated for a clinical diagnosis of a cyst of the tongue. The pathological diagnosis was a thyroglossal duct cyst. There has been no evidence of recurrence as of 6 months after the operation, and the function of the tongue has improved.View full abstractDownload PDF (2444K) -
Analysis of factors related to flap necrosisKazuhide MATSUNAGA, Tetsuji NAGATA, Noritaka ISOGAI, Kazunari OOBU, Ma ...2004 Volume 50 Issue 7 Pages 434-437
Published: July 20, 2004
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSWe studied patients who had flap necrosis after microsurgical reconstruction for orofacial defects. Among 64 patients, 5 had flap necrosis, resulting in a survival rate of 92.2%. All patients with flap necrosis underwent preoperative therapy. There was no significant difference in average age between patients with flap survival and those with flap necrosis; however, all patients with flap survival were younger than 50 years. The patients with flap necrosis had a significant decrease in postoperative pulse pressure, especially during the first and second postoperative days. Among the 5 patients with flap necrosis, 4 had a decrease in postoperative pulse pressure. Three patients concurrently had swelling in the submandibular and neck regions due to hematoma and underwent decompression procedures. On the basis of these results, we conclude that factors such as the postoperative pulse pressure and hematoma negatively affected flap blood flow.
Early detection and elimination of these factors are considered essential.View full abstractDownload PDF (599K) -
Masaaki TAKECHI, Nobuyuki KAMATA, Keiko KUME, Tetsuya YUASA, Seiko TAT ...2004 Volume 50 Issue 7 Pages 438-441
Published: July 20, 2004
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSWe report a case of multiple oral cancer with aplastic anemia.
The patient was 25-year-old man who was referred to our department for treatment of a mass in the right side of the maxillary gingiva in July 2001. He was given a diagnosis of aplastic anemia at 7 years of age. The maximum amount of mouth opening was 15mm, and a mass with an ulcer was present in the right upper molar region. Computed tomographic examination showed a mass and bone defect in the right maxillary sinus. A biopsy was performed, and the histopathological diagnosis was squamous cell carcinoma. After radiation therapy (external irradiation with 60Co-γ rays), we conducted operation. Red cell and platelet transfusions as well as granulocyte colony-stimulating factor (G-CSF) administration were performed before operation because of decreased numbers of blood cells, and the patient underwent a pertial maxillectomy.
In October 2002, a tumorous lesion appeared in the left side of the mandibular gingiva, and a biopsy revealed squamous cell carcinoma. After the platelet transfusion, resection of the tumor was performed. There has been no evidence of recurrence or metastasis for more than 1 year after surgery.View full abstractDownload PDF (1547K) -
Minoru MIYAKE, Akinori IWASAKI, Hitomi SAITO, Yumiko OHBAYASHI, Shunic ...2004 Volume 50 Issue 7 Pages 442-445
Published: July 20, 2004
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSA giant dental calculus suspected to be a neoplastic lesion is reported.
The patient was a 50-year-old woman. She had severe anemia caused by a uterine tumor.When she was treated for anemia at the hospital, an internist found an abnormal and extremely large hard mass in her mouth. She was referred to us for treatment of the lesion in her mouth after the transfusion therapy.
At presentation, we noticed that the patient had an extremely bad oral odor and poor oral hygiene. As for the giant mass of the oral floor, a neoplastic lesion was suspected because of its morphological features. The final diagnosis was a dental calculus on three-dimensional computed tomography, scintigraphy, and pathological biopsy.
The giant dental calculus was carefully removed, and the patient was instructed to maintain a sufficient level of oral hygiene to keep her mouth clean. The weight of the removed calculus was 30.5 grams. For 2 years 11 months, no redeposition of dental calculus has occurred.View full abstractDownload PDF (2227K) -
Hiroyuki SHIMOMURA, Tetsuji KAWAKAMI, Yuichiro IMAI, Shigeru TATEBAYAS ...2004 Volume 50 Issue 7 Pages 446-449
Published: July 20, 2004
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSThe microvascular Doppler (MD) is a doppler system specifically developed and produced for clinical applications involving microvessels. The MD can record hemodynamic variables from vessels as small as 0.2mm, and its high resolusion enables the depth of recording to be adjusted in steps of 0.1mm. We used an MD device to intraoperatively monitor blood flow velocity of the prepared superficial temporal artery during surgery to treat dislocation of the temporomandibular joint (TMJ).
We describe our experience with a 33-year-old man with moyamoya disease who had previously undergone STA MCA anastomosis at 32 years of age. He was examined at the Department of Oral and Maxillofacial Surgery, Medical University Hospital on January, 2002because of disturbance of mouth closing. The clinical diagnosis was habitual temporomandibular dislocation. Conservative treatment was unsuccessful. On February 2002, mobilization of the TMJ was done under general anesthesia. The superficial temporal artery was exposed, and blood flow was managed with the MD. Neither hypertension nor tachycardia occurred, and no vasodilators were used during general anesthesia. We were able to perform mobilization for dislocation of the TMJ, with no complications. As of about 18 months after the operation, the status of moyamoya disease and the response to TMJ treatment have been good.View full abstractDownload PDF (2475K)
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