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Volume 54, Issue 9
Displaying 1-9 of 9 articles from this issue
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Chang-Hoon Chae, Jun-Woo Park2008 Volume 54 Issue 9 Pages 510-516
Published: September 20, 2008
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSWe have found out the relationship of nanoemulsion containing nano vitamin C, E and propolis and gingival disease. We have confirmed effect of nanoemulsion through the experiment of in vivo and in vitro. We tested cell viability of gingivalfibroblast cells by MTT assay and m RNA appearance of interleukin-1 β, using mouse that was guided inflammation. Anti-microbacterial activity for Antibacterial effect's experiment was carried out by using S.aureus and E.coli. In addition, inflammation tissue has been observed with scanning electrical microscopy. In thisstudy, expression of interleukin-1βA was decreased after adding nanoemulsion containing nanovitamin C, E and propolis. We've also obtained good results from the test of Antibacterial effect against S.aureus and E.coli. Also, swelling of inflammation tissues observed by scanning electrical microscopy has gone down.
In conclusion, we have gained confidence that nanoemulsion containing nano vitamin C, E and propolis has very high Antibacterial effect against bacteria in oral. And it made us guess that inflammation of gingival reduces after decreasing interleukin-1 β.
Thus, we expect that nanoemulsion containing nano vitamin C, E and propolis gives good effects to patient having gingival disease.View full abstractDownload PDF (3981K) -
Yutaka FUKUMOTO, Yasuyuki SUZUKI, Shiro SHIGEMATU, Nahoko YOSHIDA, Eri ...2008 Volume 54 Issue 9 Pages 517-521
Published: September 20, 2008
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSWe statistically analyzed factors that influence anticoagulant effect after tooth extraction in patients receiving oral warfarin therapy. The study group comprised 60 of 109 patients who were receiving warfarin and presented at our hospitalfor tooth extraction from August 1991 through December 2001. The Prothrombin International Normalized Ratio (PT INR) of these 60 patients was measured and followed up until 4 weeks after tooth extraction. Multiple linear regression based on AMOS was used for statistical analysis. The dependent variable was the period oftime required after tooth extraction for the PT INR (cardiologist-determined PT INR), a cardiologist-determined coagulation index for the purpose of cardiovascular therapy, to recover to its pre-extraction level. Our study revealed that anticoagulant effect after tooth extraction was influenced by a history of prosthetic heart valve placement (prosthetic valve), the dosage of warfarin administered (the dosage), the numbers of days of treatment cessation and of administering a reduced dose of warfarin, and the cardiologist-determined PT INR. The effects of prosthetic valve and the number of days of cessation of warfarin treatment were statistically significant (partial regression coefficient, 0.31). The influence of the number of days of treatment cessation was indirectly, affected by the prosthetic valve, the dosage, and the cardiologist-determined PT INR.View full abstractDownload PDF (1002K) -
Masaki OGITA, Atsushi ABE, Mikio SHIMIZU, Atsushi NAKAYAMA, Junichi IS ...2008 Volume 54 Issue 9 Pages 522-525
Published: September 20, 2008
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSCerebro-costo-mandibular syndrome (CCMS) is a rare congenital anomaly that combines severe micrognathia, characteristic rib gap defects, and mental retardation.The neonatal mortality rate for this syndrome is 30% and that before 1 year of age is 60%. Although several hereditary cases have been reported, the true etiology is unknown. We describe a patient with CCMS in whom palatoplasty was performed at 3 years 8 months. We followed up the patient until 6 years of age.
Respiratory care was carried out just after birth until 3 months. Because a bone defect of the hard palate and a submucous cleft palate were found, the patient was referred to our hospital at the age of 3 years 5 months.
After assessment of her general condition by a pediatrician, palatoplasty was performed. We were concerned about the risk of respiratory disorder caused by airway obstruction, but the postoperative course was uneventful. Speech management with a speech appliance was performed to improve postoperative velopharyngeal insufficiency.
Such cases with mild airway obstruction can be misdiagnosed as Pierre Robin Sequence when rib disorders are not found. It was suggested that rib disorders should be examined by X-ray films in such children with severe micrognathia.View full abstractDownload PDF (2665K) -
Una CHO, Hisao SHIGEMATSU, Yuko TAKAHASHI, Yoko WATANABE, Akio TANAKA, ...2008 Volume 54 Issue 9 Pages 526-530
Published: September 20, 2008
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSThis report describes a rare case of inclusion cyst occurring after secondary bone grafting (SBG) in the alveolar cleft, with a brief discussion. An 18-year-old girl was referred to our hospital for evaluation of a repaired congenital alveolar cleft and re-bone-grafting on February 21, 2007. According to her medical history, operative closure of the cleft lip and palate was performed at an other hospital. In addition, SBG was performed at the age of 9 years 9 months. At the first visit to our department, the bone-bridge was not sufficient for orthodontic tooth movement, despite SBG. X-ray films revealed not only postoperative resorption of the transplanted bone, but also a cystic lesion with a relatively well circumscribed margin at the midline of the maxilla. On March 20, extirpation of the cystic lesion and re-bone grafting was performed. The cystic lesion, measuring8 mm in diameter, was removed. The surgical area did not communicate with the nasal cavity, and alveolar bone grafting was done successfully. Histopathological findings indicated a pseudocyst associated with a foreign-body reaction. Immunohistochemistry for hard a -keratins detected immunoreactivity on the foreign bodyin the cystic space. These findings suggested a so-called inclusion cyst occurring after SBG.View full abstractDownload PDF (3010K) -
Aya NAMBA, Hideki NAKAYAMA, Kazutoshi OHTA, Takehisa OHBAYASHI, Tomoko ...2008 Volume 54 Issue 9 Pages 531-535
Published: September 20, 2008
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSWe report a 61-year-old man with ectopic thyroid tissue in the left side of the oral floor. He had a painless and elastic hard mass suspected to be a sublingualgland tumor in the left side of the floor of the mouth. On MRI, the mass clearlyshowed low density areas on T1 and T2 images. On dynamic studies, the mass was enhanced in the early stage, suggesting a malignant tumor. On plain CT, however, the lesion was high density as compared with the muscles, and there was no thyroid gland in the normal position. Then, thyroid scintigraphy (99mTc O4-, 201T1-Cl, and 123I) was performed and confirmed that there was no uptake in the neck, but in the left side of oral floor. Thyroid function test results were within the normal range. We diagnosed the mass to be ectopic thyroid tissue. This patient was followed without treatment for about 3 years.View full abstractDownload PDF (4054K) -
Keinoshin WADA, Yoshiki ISHIDA, Yasutaka OJIMA, Shinjiro IDO, Shinshou ...2008 Volume 54 Issue 9 Pages 536-540
Published: September 20, 2008
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSA 63-year-old woman was referred to our hospital because of trismus. Clinical examinations revealed severe trismus and severe stiffness of the masseter and sternocleidmastoid muscles, but there were no symptoms of temporomandibular disorders, maxillofacial tumors, or infectious diseases. Blood examinations showed a marked increase in serum creatine phosphokinase activity. The cerebrospinal fluid was normal. These findings led to the clinical diagnosis of tetanus. The patient was admitted to the hospital immediately and received antibiotics, midazolam, and propofol. However, she refused antitetanic human immunoglobulin to avoid the risk associated with blood products. We exchanged some documents that certified our exemption from responsibility for not using antitetanic immunoglobulin beforethe operation. Tracheal intubation and tracheotomy were performed because of tetanus dorsalis, airway obstruction, and circulatory disturbance. She was discharged on the 86 th hospital day. There were no functional sequelae.View full abstractDownload PDF (1641K) -
Yasumitsu KODAMA, Kazuhiro ONO, Takanori ARASHIYAMA, Koushi OSEKI, Mas ...2008 Volume 54 Issue 9 Pages 541-545
Published: September 20, 2008
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSWe describe an 88-year-old woman with gas-forming submental cellulitis in whom nonsteroidal antiinflammatory drug (NSAID)-induced gastric ulcer led to hemorrhagic shock during treatment of an odontogenic infection. Hemodynamic treatment had to take priority, and intensive treatment for inflammation could not be performed. This apparently led to the development of descending necrotizing mediastinitis. During the six days of hospitalization, she took a total of 6 tablets of loxoprofen sodium (60 mg) and 1 diclofenac sodium suppository (25 mg) for analgesia after treatment.
Retrospectively, if decisive and aggressive treatment for inflammation had been performed earlier after hospitalization, inflammation may have resolved sooner. Our experience reconfirms that the initial treatment of odontogenic infection is extremely important in very elderly patients. Even if NSAIDs are received for a short period of time in small doses, gastrointestinal hemorrhage can occur, as in our patient. Patients at high risk for gastrointestinal ulcer should receive prophylactic treatment with cyclo-oxygenase 2 inhibitors orproton pump inhibitors.Generally, very elderly patients have a high risk of complications because of considerable age-related declines in physical ability and functional reserve of organs. Very cautious treatment is therefore necessary.View full abstractDownload PDF (2682K) -
Yasuo OKADA, Masataka KATAGIRI, Tsuyoshi IIHAMA, Michiko MORIDE, Izumi ...2008 Volume 54 Issue 9 Pages 546-549
Published: September 20, 2008
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSActinomycosis is a specific inflammatory disorder infected by actinomycetes, oneof oral resident flora. Although actinomycosis frequently arises as gnathitis orperignathitis in the oral and maxillofacial region, it is rarely localized in the oral soft tissue. This report deseribes a rare case of actinomycosis in the buccal region. A 43-year-old man visited our hospital because of a soft mass in the left buccal region, which had gradually increased in size 2 weeks before admission. We clinically diagnosed the lesion as a fibroma or abscess of the left buccal region. Excision of the mass was performed, and antibiotics were given. Since various sizes of drusen were histopathologically observed in the specimens, the final diagnosis was actinomycosis. As for pathogenesis, actinomycetes seems to cause infection by decubital ulcers due to bite injuries. In addition to oral and dental hygienic guidance, adequate treatments for peripheral periodontitis, apical periodontitis, tooth malalignment, and tooth loss were performed.Then, the prognosis is good.View full abstractDownload PDF (2747K) -
Rui WAKABAYASHI, Kaori YAGO, Satoru MORIKAWA, Taneaki NAKAGAWA, Soichi ...2008 Volume 54 Issue 9 Pages 550-554
Published: September 20, 2008
Released on J-STAGE: April 22, 2011
JOURNAL FREE ACCESSMassive osteolysis is an extremely rare disease associated with aggressive resorption of bone. It is usually indolent and progresses rapidly. However, the etiology of this disease remains to be elucidated. We describe a 25-year-old woman who presented with massive osteolysis of the maxilla and mandible accompanied by severe pain and paralysis of the mental nerve. We performed a partial maxillectomy and a mandibular segmentectomy in March 2005. Approximately 3 years after the operation, the bone lysis of the jaws resolved and the associated pain disappeared. There has been no evidence of recurrence.View full abstractDownload PDF (3513K)
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