Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Volume 34 , Issue 10
Showing 1-27 articles out of 27 articles from the selected issue
  • Yoshinori JINBU, Shunichiro INOUE, Yasuo KITAJIMA, Shigeaki KOTO, Yoko ...
    1988 Volume 34 Issue 10 Pages 2091-2095
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Pemphigus is an antibody-mediated autoimmune skin disease that causes blistering of oral mucous membranes as well as skin, and it is generally considered that the blisters are induced by loss of cell to cell contact in the keratinocytes. However, the details are still unclear. In order to investigate the molecular mechanism of blister formation in oral mucous membranes, we observed the effects of pemphigus antibody on the organization of keratin intermediate filaments (KIFs) in cultured oral keratinocytes. After incubation with serum obtained from a patient with pemphigus vulgaris for 96 hrs at 37°C, the distribution of KIFs was changed from a fibrous structure to a dotted structure around the nucleus in some of the cells from normal gingiva and soft palate, but such changes were not observed in cells from normal tongue. These results suggest that the keratinocytes from the gingiva and soft palate may be more sensitive to the pemphigus antibody than cells from the tongue.
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  • Hirokazu NAKAMURA, Eriko YAMADA, Kanichi SETO
    1988 Volume 34 Issue 10 Pages 2096-2105
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    We have investigated the psychosocial aspects of 55 mandibular prognathism patients, 20 males and 35 females, for a period of one year after their operations, by interview based upon our own questionnaire.
    1) For many patients, the intermaxillar fixation was considered to be the most uncomfortable procedure during the mandibular prognathism treatment.
    2) 80% of the males and 78% of the females showed improved mastication after the surgical procedure.
    3) Only 21% of the subjects had difficulty in pronunciation after the surgery. An improvement in pronunciation was achieved in 35% of the males and 48% of the females.
    4) The evaluation, by means of sliding scales, showed that the majority of the postoperation subjects inclined to regard their deformity as slight or none, and their facial appearance no longer suffered.
    5) The 38% of the male patients attached great importance to the improvement of mastication after surgery. And the improvement of feeling, appearence, pronunciation followed. For the female patients, 55% took the improvement of facial appearance as most important. And the imporovement of mastication, feeling, and pronunciation followed.
    6) 6% of the male and 30% of the females showed positive changes in their individual and social life-style after the operation. We did not find out behavioral problems among the patients.
    7) 65% of the males and 77%of the females had no or only slight self-consciousness after surgery.
    8) 80% of the males and 85% of the females showed a high degree of satisfaction with the results of the operation. Some patients showed a slight dissatisfaction with their facial appearence and complications after surgery.
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  • Kazuya MAEDA, Masanori NASU, Takasuke OHKI
    1988 Volume 34 Issue 10 Pages 2106-2118
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    The process of remission after CO2 laser irradiation of the rat jaw bone was assessed using an X-ray microanalyzer in comparison with dental bur holes, and the effects of the CO2 laser were studied. The following results were obtained:
    1. A comparison of SEM of changes after laser irradiation revealed a convex profile with degeneration of the bone at the margin of the defective site. There was a slightly depressed area of bone fusion between the bone at the margin and the bone at the distant site for 15 days immediately after irradiation, although the defective site presented only slight new bone generation even 45 days after irradiation and was still surrounded by degenerated bone; the most of the site was covered with irregular, newly generated bone.
    2. As a result of a comparison of analyzed line images among the laser groups, the X-ray intensity for Ca and P reached a maximum at the margin of the defective site immediately after laser irradiation, and the intensity transiently decreased at a site ca. 50μm distant from the defective site. The X-ray intensity at a distant site ca. 100-300μm away from the defective site was equivalent to that in the non-irradiation group, but it increased 3, 10 and 15 days after irradiation. Irregular line images associated with new bone generation at the defective site and its periphery were obtained 45 days after irradiation.
    3. Secondary electron images taken from the group given dental bur holes showed a clear marginal border around the perforated site immediately and 3 days after perforation. Newly generated bone was observed at the margin of the perforated site 10 and 15 days after perforation. On the 45 th day after perforation the perforated site width had narrowed.
    4. Analysis of line images revealed an X-ray intensity for Ca, P and Mg which was the same level as that at a site distant from the perforated site, even at the margin of the perforated site, immediately and 3 days after perforation. The pattern of the intensity changed in a wave-like form for Ca, P and Mg, over an area ranging from the margin of the perforated site to the perforated site 10 days and 15 days after perforation, suggesting new bone generation. The width of the perforated site further decreased and the pattern in the vicinity of the site was also unstable on he 45th day after perforation, although the wave form was similar to that of a healthy bone.
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  • Toshitaka MUTO
    1988 Volume 34 Issue 10 Pages 2119-2138
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Even today, few transplantable bone-forming osteosarcomas are available. Therefore, we tried to produce such tumors experimentally in the bone of rats with administration of 4 NQO and/or 32P. The results were as follows:
    1) No malignant bone tumor developed in 100 g rats with a single administration of 4 NQO into the mandible and femur in doses of 2 or 4mg per body weight.
    2) Combined administration of 32P (2.8μci/g) with 4 NQ0 (0.17-1mg/100g) produced tumors in 77 out of 87 rats. Histologically tumors were classified as osteosarcoma (78.0%), fibrosarcoma (15.8%) and others. The locally inoculated 4 NQO showed less inductivity of osteosarcoma, but increased producing of fibrosarcoma.
    3) Several characteristics of induced osteosarcomas were observed: Osteosarcomas with higher ossification had a longer doubling time and a higher incidence of lung metastasis and a higher value of serum alkaline phosphatase were observed. These findings could serve clinical diagnosis and therapy of human osteosarcomas.
    4) Three transplantable osteosarcomas (MSU-A 3, -D 16, -E 3) in vivo and one osteosarcoma cell line (MSK) in vitro were established. These strains and one cell line showed a marked osteoid forming activity when they were inoculated subcutaneously into the back of F 344 rats. We believe that these tumors would be very useful as a model of osteosarcomas.
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  • Masashi TABATA
    1988 Volume 34 Issue 10 Pages 2139-2158
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    A 2% acetone solution of 9, 10-dimethy1-1, 2-benzanthracene (DMBA) was applied to lingual mucosa of hamsters after scratching with a root canal broach three times a week. Using mainly the freeze-fracture method, the quantitative study of intercellular junctional changes was made during the process of carcinogenesis and in squamous cell carcinoma in the oral mucosa of hamsters. Replicas were examined and photographed in a single blind fashion, and the frequency and size distribution of gap junctions and desmosomes were computed planimetrically. Precancerous lesions were classified into two groups:(a) mild and moderate dysplasia, and (b) severe dysplasia. The results obtained were as follows:
    1) Intercellular junctions were very frequent in the normal intermediate layer and less frequent in the normal basal single layer of cells.
    2) Gap junctions decreased significantly in the basal layer of the severe dysplasia and in the marginal area of the invasive carcinoma.
    3) Desmosomes decreased significantly in the intermediate layer of the severe dysplasia and in the invasive carcinoma.
    These results indicate that the decrease of intercellular junctions correlates with the severity of morphological alteration in the dysplastic epithelium and the deficiency of intercellular junctions before invasion may be one of the important factors eventually permitting the development of the diffusely infiltrating cells which are characteristic of highly malignant tumors such as squamous cell carcinoma.
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  • Toshiyasu YAMASHITA
    1988 Volume 34 Issue 10 Pages 2159-2177
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Ten salivary calculi in the submandibular duct, one salivary calculus in the submandibular gland, ten cholesterol gallstones, and ten renal calculi were used in this study. All were examined by the scanning electron microscope (SEM), computer aided microanalyser (CMA), and energy dispersive spectrometer (EDS).
    The surface structure of salivary calculi was classified into three types. In one area a rocklike structure was observed. In another area there was a thickly polygonal-body type structure, and in another area a globular like structure was observed. In cholesterol gallstones, the surface was observed to have board-like crystals and in renal calculi, octahedron crystals.
    The cut surface of salivary calculi was morphologically made of core and stratiform structure. The core was organized by the gathering together of micro-cores. The distribution of Ca and P in the micro-core area was different from that in the other area. It was observed that the structure of the cut surface was formed by circle-like or polygonal-like shapes accmulated in a comb like pattern. The surrounding of each micro-core organization unit was observed to be a radial arrangement of club type structures.
    The cut surface of cholesterol gallstones showed shell type structures with high calcium density and low phosphorous density.
    The morphology in the cut surface of renal stones was made up of core and stratiform structure, and each core organization unit had an ellipse-like structure in the cut surface but it was smaller than the one of the salivary calculi.
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  • Sadahiko SHIBATA
    1988 Volume 34 Issue 10 Pages 2178-2187
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    The effect of implants of fresh autogenous bone marrow (BM) and hydroxylapatite particles (HAP) in subcutaneous tissues and bone defects was studied experimentally in a monkey. HAP, BM and a mixture of HAP and BM (MIX) were implanted into the subcutaneous tissues and jaw bone defects. After the implantation, histological findings were studied at various intervals, particular attention was paid to new bone formation.
    No bone formation was found in any cases using HAP alone in subcutaneous tissue, but, new bone was formed in cases using BM and MIX in subcutaneous tissues. The frequency of such bone formation in cases using MIX was higher than that of cases using BM. This result may be caused by the microenvironment around HAP with or without BM. The bone formation did not occur in direct contact with HAP, so HAP can not act as nidus for newly formed bone. Multinucleated giant cells in close contact with HAP appeared both in cases of HAP- and MIX-groups, and their numbers were greater in the MIX-group when compared to the HAP-group, while they disappeared as bone formation progressed. The bone formation in jaw bone defects was more prominent in the MIX-group than that in the HAP-group, and the HAP was completely surrounded by lamellar bone at 90 days in the MIX-group.
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  • Hiroshi FUJITA, Masafumi SHIMAZU, Kaoru OHSAWA, Toshiya SHIBATA, Shin- ...
    1988 Volume 34 Issue 10 Pages 2188-2196
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    We have previously reported that an experimental model of disseminated intravascular coagulation (DIC) could be induced by continuous infusion of endotoxin (ET) at a dose of 3mg/kg during 3hrs, in rabbits. Using this model, the effects of prostaglandin E1 (PGE1) against DIC were investigated. Our study was made in control rabbits and rabbits infused with PGE1. The animals were divided into 4 groups as follows;
    Group I (control group): physiological saline infusion d-ET (3mg/kg) infusion
    Group II (PGE1 group): PGE1 (125ng/kg/min) infusion+ET (3mg/kg) infusion
    Group III (PGE1 group): PGE1 (25ng/kg/min) infusion+ ET (3mg/kg) infusion
    Group IV (PGE1 group): PGE1 (5ng/kg/min) infusion+ET (3mg/kg) infusion
    Tentative diagnostic criteria for DIC were designed as DIC scoring system. The DIC score was useful to determine the degree of the DIC state (DIC score>6 points) and evaluate the effects of PGE1 infusion against DIC. The results of the present study demonstrated the following scores for each group: 7.4±0.9 in Group I, 2.3±1.2 in Group II, 2. 8±1.5 in Group III, and 3.5±1.0 in Group IV. The inhibition of development of DIC was noted in PGE1 groups. However, mortality was not reduced in Group II against Group I. These results suggested that a moderate dose of PGE1 (Group III) might be most effective for prevention of DIC.
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  • Hideaki SAKASHITA, Masaru MIYATA, Morimoto HAYASHI, Eisuke FUJIMOTO, K ...
    1988 Volume 34 Issue 10 Pages 2197-2203
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Central mucoepidermoid carcinoma of the mandible is rare.
    The patient, a 68-year-old woman, was referred to our hospital with the chief complaint of painless swelling at the left side of the jaw.
    Radiological examination showed a multilocular cystic lesion with an eggshell-like cortical expansion at the left mandible, locating from the ramus to the premolar region.
    The pre-operative impression was an ameloblastoma. The left half of the mandible was resected, and it was reconstructed with a metal plate.
    Pathologic examination of the sections of the tumor revealed a picture of a central mucoepidermoid carcinoma.
    The case was reported with some comments based on reviewing the literature.
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  • Koichi YAMAMOTO, Hiroshi ODAKE, Katsuo BANBA, Fujio MADACHI, Masayuki ...
    1988 Volume 34 Issue 10 Pages 2204-2208
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    This report presents a case of a man aged 46, in which swelling of the lymphonodisubmandibulares was the principal (symptom) and which was diagnosed as lymphogranular toxisoplasmosis by serological investigations.
    The symptoms decreased with the administration of an ST combination product of Sulfomethoxazol and Trimethoprim.
    Further, this infection was supposed to derive from the intake of uncooked livers and hearts of cows and pigs.
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  • Osamu TOMISHIMA, Masahiro YAMASHIRO, Hajime SUNAKAWA, Takashi KINJO, A ...
    1988 Volume 34 Issue 10 Pages 2209-2215
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Characteristics of cervical metastasis after treatment without local recurrence in Stage I and II of tongue cancer were investigated from clinico-pathological findings.
    Metastasis after treatment was found in 5 out of 23 cases.The incidence of lymphnode metastasis by therapeutic modality indicated that cervical metastasis occurred in one case (8.3%) treated by surgery, and in 4 cases (36.4%) of those treated with radiotherapy. In these 4 cases, the total dose of radiation to the primay lesion ranged from 8, 500 rads to 15, 959 rad, and averaged 11, 840 rad. Duration from the time of starting the treatment to that of palpation of cervical metastasis was 4-7 months.
    Location of metastasis nodes were level I and II in the level of involvement proposed by the UICC.Clinically, the metastatic rate was 33.3% in T1, 14.7% in T2, 22.2% in exophytic growth type, and 20.0% in endophytic growth type.Histologically, these cases were classified into three of grade 2 (4/8, 50.0%) and one of grade 4 D (1/1, 100%) in the mode of invasion.On the differentiation of the tumor, metastasis was found in 2 cases (18.2%) of well differentiated, in 2 cases (22.2%) of moderately differentiated and in one case (33.3%) of poorly differentiated.
    C. P. the 4 cases in which metastasis occurred were low grade malignancies.This suggested that metastasis that occured after treatment was related to the therapeutic method.
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  • Joji KATO, Yutaka SAITHO, Izumi MATAGA, Morio OZAKI, Kazuyoshi OZAWA, ...
    1988 Volume 34 Issue 10 Pages 2216-2222
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    A total of 24 non-dialysis patients with chronic renal failure were screened foe symptoms of the oral and maxillofacial regions.
    1) In the questionnaire, six of the 24 patients complained of xerostomia. The symptom followed the manifestation of renal failure in five patients, suggesting its intimate association with the morbidity of renal failure.
    2) In the physical findings, as many as 25% of the patients presented with the anemic color of the oral mucosa which seemed to reflect the anemia complicating chronic renal failure. Xerostomia and dry lip were seen in relatively high percentages, 16.7% and 25.0%, respectively. It was thus made clear that such dryness developed prior to the initiation of dialysis.
    3) The average amount of mixed salivation of 17 patient who had been put at rest for 10 minutes stood at 1.45ml+0.69ml (mean+S.D.), a value that was slightly lower than normal. In addition, an inverse correlation between salivary flow and the history of renal failure was noted and thus it was supposed that the morbidity and the progress of renal failure had some effect on the salivary secretion.
    4) The blood examination did not reveal any conspicuous findings but ones characteristic of renal failure. The degree of anemia in the gingiva was in an inverse correlation with RBC and thus the anemic color of the gingiva seemed to help estimate the condition of anemia, a complication frequently found in renal failure patients.
    5) When compared with dialysis patients, it was supposed that xerostomia developed before the initiation of dialysis therapy. Regarding bone abnormalities and paresthesia, there were no findings characteristic of non-dialysis patiens, but further investigation is necessary in this respect.
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  • Sumiko MATSUI, Yukihiro MICHIWAKI, Ken-ichi SAITOH, Yoshiroh MATSUI, H ...
    1988 Volume 34 Issue 10 Pages 2223-2230
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    The calcifying odontogenic cyst is histopathologically characterized by the appearance of ghost cells and calculous deposits on the epithelial layer of the cyst wall. This lesion is defined as a non-neoplastic lesion by the WHO International Classification of Odontogenic Tumors and Allied Lesions.
    Two cases of calcifying odontogenic cyst associated with compound odontoma are presented. In one of these cases, the relationship between the cyst and odontoma is unclear. In the other case, it is suggested that the cyst developed secondarily from the epithelium in the formation of odontoma.
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  • Kazuhiko TANIO, Kazuo RYOKE, Shuji ANDOH, Kazumi OKAMOTO, Takaaki OGAW ...
    1988 Volume 34 Issue 10 Pages 2231-2236
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    A modified method of the Naumann's method reported in 1974 was applied to a patient afflicted with temporomandibular luxation with Parkinson's disease. These summary was as follows:
    A 74-year-old woman visited our clinic complaining of disturbance with closing her mouth, and was complicated with Parkinson's disease. Her temporomandibular joints were completely dislocated. A trial of ordinally manual reposition was given without success. Open reduction in temporal approach according to the Naumann's method was performed under general anesthesia. In our method the use of hydroxyapatite block for iliac bone graft was substituted. There has been no recurrence of dislocation since the operation. In our case this patient's zygomatic arch was narrow and thin, so that other surgical procedures such as the Leclerc method could not have been applied. An application of hydroxyapatite block led to good results for habitual luxation of the temporomandibular joint.
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  • Akihiro NITTA, Masahiro MAKI, Yasuyoshi UJI, Kiyomi KUWATA, Rie KATO, ...
    1988 Volume 34 Issue 10 Pages 2237-2241
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    The CR system has been applied to almost all types of roentgenography. In oral surgery, it has been used for special techniques such as panoramic roentgenography, conventional radiography of the head, and tomography of the jaw joint as well as for extraoral techniques including the frontal radiography of the head with favorable results.
    In this study, we employed this CR system in panoramic roentgenography, which is performed frequently in oral surgery, to evaluate its abilities to delineate (1) anatomical structures and (2) lesions.
    (1) Ability to delineate anatomical structures.
    The bone structures, borders of the cortical bone, and the relationship between the root of the tooth and the jaw bone were more clearly represented, and the blur in the anterior teeth region characteristic of tomography was slightly reduced.
    (2) Ability to delineate lesions.
    The course of fracture lines, margins of cysts and tumors, relationship between the implanted tooth and the jaw bone, and anatomical structures around the lesions of siagonantritis were more readily evaluated, suggesting improved imaging ability of the CR technique.
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  • Kunio FUJITA, Masaaki ICHII, Kouzou IWATA, Eisaku SANO, Hisao ISHIDA, ...
    1988 Volume 34 Issue 10 Pages 2242-2245
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    We report a case of a 67 year old woman treated for hemangioma with 2 phleboliths on the upper lip.
    The 67 year old woman in this case had swelling of the upper lip which had been present for approximately 3 years. There was sudden increase in size the month before the first medical examination. No pain was experienced. The color was dark violet and was removed under local anesthesia. Histological examination revealed cavernous hemangioma.
    Further more, the quantitative analysis of the 2 phleboliths in our case showed that the volume of calcium of 1 of the phlebolith was nearly equal to that of the cortex of the man dible. The other phlebolith showed a lower volume than this.
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  • Hiroshi MURASE, Tadamitsu KAMEYAMA, Katsumi TANAKA, Syunichi TANAKA, K ...
    1988 Volume 34 Issue 10 Pages 2246-2251
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Mucous membrane pemphigoid is a vesiculobullous disease of unknown etiology which is relatively uncommon.
    This disease is diagnosed on the basis of histopathologic and immunofluorescence studies in biopsy of the oral mucosa.
    A 62-year-old woman with erosion on the gingiva visited our clinic.
    Oral examination revealed erosion on the gingiva. Histopathological features showed a definite subepithelial vesicle formation and t nonspecific chronic inflammatory infiltrate in the connective tissue. The entire epithelium was intact and no evidence of acantholysis was found.
    The results of direct immunofluorescent staining demonstrated a linear basement membrane zone pattern with IgG and C3.
    The diagnosis of mucous membrane pemphigoid was established.
    Although the oral lesion has not healed completely after 2 years of observation, the patient's symptoms were alleviated by topical steroid therapy and by brushing after scaling. The clinical and histopathological characteristics of mucosal pemphigoid were discussed.
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  • Takeshi HAYASHI, Tomoji MORIYAMA, Masayoshi SAKUDA
    1988 Volume 34 Issue 10 Pages 2252-2256
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Three cases of intraoral foreign bodies, which are rare in complications after removal of the impacted third molars, have been presented.
    In one case of a maxillar third molar and two cases of mandibular third molars, the patient's symptom underwent complete resolution after removal of the foreign bodies.
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  • Rumiko MATSUO, Kouji FUJIWARA, Shigeru OHYAMA, Hirotoshi NAKAGAWA, Mas ...
    1988 Volume 34 Issue 10 Pages 2257-2261
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Ameloblastoma is the most common tumor among odontogenic tumors and frequently occurs in the mandible. According to WHO classification, the majority of the tumors had follicular or plexiform histologic pattern, and basal cell type was relatively rare.
    A case of maxillary anieloblastoma of basal cell type is presented. A 64 years-old man was referred to our clinic with a chief complaint of incomplete wound healing in 7 extraction socket. The socket was filled with soft tissue mass without covering epithelium. The mass was resected under general anesthesia and the diagnosis of ameloblastoma of basal cell type was established.
    The tumor cell, resembling basal cells, were examined by electron microscopy and compared with ultrastructures of ameloblastoma by several authers.
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  • Noriko YAMASHITA, Kazumasa SUGIHARA, Masaaki KAWATA, Masashi TABATA, T ...
    1988 Volume 34 Issue 10 Pages 2262-2270
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Cementifying fibroma is a rare neoplasm of the bone with a predilection for the mandible. We experienced a case of cementifying fibroma of the right lower posterior region of the mandible in a 61-year-old male. The tumor was surgically removed under local anesthesia. The obtained specimen was examined with light and electron microscopes.
    Light microscopic findings: The tumor was composed of delicate interlacing collagen fi bers, interspersed with large numbers of cellular elements and cementum-like hard tissues.
    Transmission electron microscopic findings: The tumor was found to consist of fibroblastlike cells, cementblast-like cells and hard tissues. The fibroblast-like cells assuming spindle or polyhedral shape, contained abundant cytoplasmic organelles and large nuclei. The nuclei varied from elongated ovoid shapes with smooth outline to polyhedral shapes with deep invagination. Intracytoplasmically, there were well developed rER, Golgi apparatus and several mitochondria. Some cementoblast-like cells also contained abundant amounts of 10 nm filaments and 10-400 nm electron-dense microgranules. The intracytoplasma of these cells usually contained electron-dense deposits and needle-shaped crystal-like structures. Within the fibrous matrix, amorphous electron-dense deposits on the collagen fiber bed were usually noted. Occasionally a small number of matrix vesicle-like structures were also present on the collagen fi bers. These matrix vesicle-like structures included electron-dense deposits or needle-shaped crystal like structures.
    Scanning electron microscopic findings: In the collagen fibrous matrix, there were numerous rounds or ovoid, structureless calcified clusters and cellular elements. Early calcifying deposition on the delicately interlacing fibrous network could also be observed around the cementum-like structure. Occasionally, coalescence of a round calcifying structure into a large cluster was also observed.
    X-ray microanalysis revealed that these clusters contain a high concentration of phosphate and calcium.
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  • Koji EBATA, Minoru SHIBATA, Yoshihiro TAKAHASHI, Toshio KANEDA
    1988 Volume 34 Issue 10 Pages 2271-2276
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    A case of gigantic congenital epulis of a new born baby was reported. The tumor measured 42×33×29 mm and was arising from B region on the alveolar gingiva.
    The tumor was removed 3 hours after birth without anesthesia. After extirpation, the baby was able to nurse satisfactorily. There has been no problem of recurrence. The tumor was diagnosed histopathologically as a benign granular cell tumor.
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  • Hisashi MIYAJIMA, Toshihiro YOSHIDA, Kazuo WADA, Junichiro BABA, Takas ...
    1988 Volume 34 Issue 10 Pages 2277-2281
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Facial deformity and many oral functional obstructions have been caused by maxillary resection. In many cases, they are usually restored by maxillofacial prosthesis. But anchoring of a maxillofacial prosthesis on the residual dentition leads to its premature destruction. And retention of the prosthesis is usually unsatisfactory when it can no longer be anchored on a residual dentition. Therefore, late reconstruction of large maxillary defects has been infrequently performed. We had an experience in primary reconstruction using fresh autogenous iliac bone graft after the resection of ossifying fibroma in the maxilla, and will report it hereunder.
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  • Toaki ONO, Fujio WAKE, Yoshiki SUGIYAMA, Akiko MAEO, Tadahiro YAMAMOTO ...
    1988 Volume 34 Issue 10 Pages 2282-2288
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Clinical statistics were performed on 931 cases of maxillofacial fracture at theSecond Department of Oral Surgery, Tokyo Medical and Dental University hospital during the 23 years from 1962 to 1986 and the following conclusions were drawn.
    1) The number of patients with maxillofacial fractures increased every year from 1962 to 1986.
    2) The majority of the patients were between the ages of 10 and 20 years old, with the incidence occurring in the 20 years old group. The male/female ratio was 3. 9: 1.
    3) In our clinic, many patients visited in August.
    4) 560 of the cases visited our hospital within 1week after injury.
    5) The most common causes of maxillofacial fractures were traffic accident in both male and female.
    6) 656 of the cases were found in the mandible, 141 case in the maxilla, 62 cases in the combined mandible and maxilla.
    7) The majority of fractures were treated by closed reduction.
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  • Toshio HARADA, Yukio INOUE, Seiji OBARA, Yasuro YOSHIMURA, Kenichi INA ...
    1988 Volume 34 Issue 10 Pages 2289-2293
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    This clinical study reported a case of maxillary sinus cancer (T4N1M0) with multiple microscopic embolization of cancer cells and coagulation necrosis in several organs on autopsy. The patient (a 76-year old female) who had been suffering from schizophrenia for 13 years was referred to our clinic for confirmed diagnosis and treatment. The histopathological examination revealed a poorly differentiated squamous cell carcinoma. She had undergone CO2-Laser vaporization of tumor cells from oroantral opening, irradiation, and chemotherapy in the first hospitalization. However, after that she rejected cancer therapy strictly, and finally died of cancer. Multiple microscopic cancer cell embolizations and coagulation necrosis were observed in various organs, such as the cerebrum, spleen liver and bilateral kidneys on the specimens obtained from the autopsy.
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  • Hideyuki SHIBA, Kimio UTIYAMA, Toshiaki KURASHIMA, Maniwa KIZU, Mitita ...
    1988 Volume 34 Issue 10 Pages 2294-2299
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Clinical usefulness of Elental. An elemental diet was studied in 23 patients who had undergone oral surgery. The nutrient was administered intragastrically in 6 divided doses daily similar to the administration schedule of a conventional enteral diet. No side effect was observed clinically except diarrhea in 11 patients.
    Laboratory data also remained within normal limits. Intragastric divided administration may deliver adequate hyperalimentation if based on a proper administration schedule.
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  • Joji KATO, Yutaka SAITOH, Atsuo OKANO, Morio OZAKI, Masanori KONDO, Ya ...
    1988 Volume 34 Issue 10 Pages 2300-2309
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    MA-7, an enteric nutrient, was administered for nutritionalmanagement and feeding of 25 patients with diseases in the oral and maxillofacial regions.Because of due considerations given to not only the tube feeding but also the intra-oral feeding this nutrient allows a long-term use, providing full satisfaction to patients.
    The administration of MA-7 tended to increase the patients' weight, serum total protein, and serum albumin, allowing effective nutritional management compared with the conventional enteric nutrients.
    The incidence of side effects, especially symptoms in the digestive tract, was low. Also no abnormality of blood components attributable to the administration of MA-7 was observed. It was concluded that MA-7 was instrumental as a enteric nutrient because it provided effective nutritional management and caused few incidences of side effects.
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  • Kazuhiko TANIO, Kazuo RYOKE, Takeshi HAMADA, Yutaka HASHIMOTO, Hiroaki ...
    1988 Volume 34 Issue 10 Pages 2310-2319
    Published: October 20, 1988
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    Clinical evaluation of Cefbuperazone (CBPZ) in 63 cases of various infections inthe oro-facial region was carried out. Bacteria were isolated from the infectious lesions and their sensitivity to Cefbuperazone was tested. The results are summarized as follows.
    1. CBPZ was subjectively evaluated by doctors who used the drug, and considered excellent in 20 cases, good in 32 cases, fair in 6 cases and poor in 5 cases, the effectiveness rate being 82. 5%. On the other hand, CBPZ was also estimated by way of a scoring system evaluation and considered excellent in 15 cases, good in 37 cases and poor in 11 cases, the effectiveness rate being 82. 5%.
    2. Bacteria were able to be isolated in 57 cases (90. 5%). Of the isolated 90 strains, 21 were anaerobic (23. 3%). These isolated anaerobics were highly sensitive to CBPZ.
    3. No remarkable side effect was observed, but elevation of S-GOT in one case, S-GPT in two cases and ESR in two cases were observed.
    According to these results, CBPZ was evaluated to be useful antibiotics for various infections in the field of oral surgery.
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