巻号一覧
100 巻 (1988)
- 11-12 号 p. 981-
- 9-10 号 p. 843-
- 7-8 号 p. 701-
- 5-6 号 p. 441-
- 3-4 号 p. 205-
- 1-2 号 p. 1-
71 巻 (1959)
- 12-2 号 p. 8243-
- 12-1 号 p. 7861-
- 11supplement 号 p. 1-
- 11-2 号 p. 7531-
- 11-1 号 p. 7095-
- 10-2 号 p. 6691-
- 10-1 号 p. 6223-
- 9-2 号 p. 5773-
- 9-1 号 p. 5405-
- 8-2 号 p. 4993-
- 8-1 号 p. 4515-
- 7-2 号 p. 4069-
- 7-1 号 p. 3623-
- 6-2 号 p. 3149-
- 6-1 号 p. 2783-
- 5-2 号 p. 2423-
- 5-1 号 p. 1989-
- 4-2 号 p. 1655-
- 4-1 号 p. 1145-
- 3supplement-2 号 p. 1-
- 3supplement-1 号 p. 1-
- 3-2 号 p. 1145-
- 3-1 号 p. 691-
- 2-2 号 p. 691-
- 2-1 号 p. 323-
- 1 号 p. 1-
前身誌
100 巻, 9-10 号
選択された号の論文の14件中1～14を表示しています
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宮田 義昭1988 年 100 巻 9-10 号 p. 843-855
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーThe thalamic afferents to the cortical taste area in the cat were studied by retrograde transport of horseradish peroxidase. The taste area extends from the lateral lip of the presylvian sulcus to the posterior part of the orbital gyrus. It is bounded anteriorly and anteromedially by area 6, medially by the fundus and medial bank of the presylvian sulcus, laterally by the first somatosensory area, and posteriorly by the insular area. The taste area receives fibers mainly from the medial smaller-celled part of the posteromedial ventral nucleus (VPMM). Cortical projections of the VPMM form a complicated pattern, but are organized roughly in a topical manner anteroposteriorly. The anterior part of the taste cortex receives fibers from the anterodorsal and posteroventral portions of the anterior two-thirds of the VPMM, whereas the posterior taste cortex receives fibers from the anteroventral, posterodorsal and posterior portions of the posterior two-thirds of the VPMM. In addition, there appears to be a mediolateral organization of cortical projections of the VPMM to the taste area. The taste cortex receives a few projections from the ventral lateral, ventral medial, submedial, paracentral, lateral central, parafascicular and medial central nuclei.抄録全体を表示PDF形式でダウンロード (892K) -
児島 完治1988 年 100 巻 9-10 号 p. 857-872
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーThe transverse size of the kidneys was measured by CT, and CT findings of the kidneys were studied in 94 patients with chronic renal failure under hemodialysis (HD), 58 patients with chronic renal failure not under hemodialysis (CRF) and 100 controls. The transverse size of the kidneys decreased according to the deterioration of renal function. The ratio of the maximal renal transverse size to the minimal vertebral size, which the author proposed as a new criterion for renal atrophy, was 1.8 in controls, 1.2 in CRF and 0.8 in HD. A kidney smaller than the vertebral body indicated chronic renal failure. Characteristic CT features in CRF were mild renal atrophy and cystic changes (41.4%). In HD, renal atrophy was more advanced, the occurrence of cystic changes was more frequent (64.9%), and there were frequent renal (68.1%) and aortic calcifications. Furthermore acquired cystic disease of the kidney (ACD) was observed (27.7%) only in HD. In this study no renal neoplasm was found in ACD. However, several complications in HD, one perirenal hematoma and six hydronephroses, were observed.抄録全体を表示PDF形式でダウンロード (4405K) -
杉田 真喜雄1988 年 100 巻 9-10 号 p. 873-883
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーTo clarify the role of antibody dependent cell-mediated cytotoxicity (ADCC) in the prevention of measles virus infection during the first year of life, ADCC activities in cord blood and peripheral blood of infants were examined by a 51Cr-release assay method. Transmission of ADCC from the mother to the newborn was also evaluated.
ADCC activities in the cord blood were demonstrated in 40 among 41 newborns whose mothers had a history of measles infection. A significant correlation in ADCC activities between cord blood and maternal blood was found (r=0.946). The antibody which mediates ADCC correlated with neither NT antibody nor HI antibody against measles virus in the cord blood. Thus, this antibody represented another group of antibody. HI antibody disappeared from the age of 6 months, while the antibody mediating ADCC remained until the age of 12 months. ADCC activities were detected even in the cord blood of newborns whose mothers were infected with measles 16 to 28 years ago. These results suggest that the antibody mediating ADCC against measles virus is transmitted from the mother to cord blood via the placenta. Furthermore, ADCC appears to play an important role in preventing the infection of infants between 6 to 12 months of age with measles virus.抄録全体を表示PDF形式でダウンロード (3744K) -
第1編 単球スーパーオキサイド産生能におよぼす加齢の影響三島 康男1988 年 100 巻 9-10 号 p. 885-893
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーSuperoxide anion ( ) plays an important role in the bactericidal activity of human monocytes. Stimulation of human monocytes by concanavalin A (Con A) and cytochalasin E (Cyt E) results in superoxide production. In this study, the generation of monocytes was assessed for variation with age. Monocytes obtained from 51 normal subjects were assessed.
The optimal concentrations of Cyt E and Con A were 20μg/ml and 100μg/ml, respectively. There was no significant difference in production between males and females. production in older subjects (65-86years) was significantly lower than that in younger subjects (20-64years) (p<0.05). The values were 11.2±3.3 nmol/min/106 cells in the former, and 12.9±2.6 nmol/min/106 cells in the latter. These findings suggest that impaired production might be one of the factors accounting for the impaired bactericidal activity of mononuclear leucocytes in the aged.抄録全体を表示PDF形式でダウンロード (570K) -
第2編 糖尿病における単球スーパーオキサイド産生能に関する研究三島 康男1988 年 100 巻 9-10 号 p. 895-903
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーMonocytes obtained from 44 diabetics were stimulated with concanavalin A and cytochalasin E, and the resulting superoxide production was assessed to see if it was affected by the degree of control of the diabetes.
In controls, the O generation was 12.4±3.0 (mean±SD) nmol/min/106 cells, and in diabetics, it was 9.9±2.9, which was significantly lower than in the controls (p<0.001).
Diabetic subjects were classified into three groups according to their fasting glucose levels: one, good control (FBS 140 mg/100ml); two, fair control (FBS>140 mg/100ml and <200mg/100ml), and three, poor control (FBS 200mg/100ml). These groups generated O levels of 11. 5±2.0, 10.0±2.2 and 8.7±3.3 nmol/min/106 cells. O generation in the poorly controled group was significantly lower than in the well controlled group (p<0.02). A negative correlation was found between O production and the hemoglobin A1 value (r=-0.48).
The untreated group showed significantly lower O generation than the insulin treated group (p<0.01).
These findings suggest that impaired O production, which leads to decreased bactericidal activity of monocytes, might be one of the factors which account for the high susceptibility of diabetics to infection.抄録全体を表示PDF形式でダウンロード (549K) -
島村 和宏1988 年 100 巻 9-10 号 p. 905-914
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーEffect of adenosine, adenosine analogs and methylxanthines was studied on histamine release induced by antigen, compound 48/80, α-chymotrypsin, substance P and neurotensin from rat peritoneal mast cells.
Adenosine inhibited anaphylactic histamine release at low concentrations but enhanced it at higher concentrations. N6-methyladenosine, an adenosine R-site analog, had a similar dual effect on anaphylactic histamine release. However, 9-β-D-arabinofuranosyladenine and 2'-deoxyadenosine, adenosine P-site analogs, had neither inhibitory nor enhancing effect. Adenosine inhibited histamine release induced by compound 48/80 and α-chymotrypsin but not the release induced by substance P and neurotensin. Not only adenosine R- and P-site analogs, but also a large variety of purine and pyrimidine derivatives inhibited compound 48/80-induced histamine release. Theophylline inhibited compound 48/80-induced histamine release. However, 3-isobutyl-l-methylxanthine, caffeine and theobromine were ineffective.
These results suggest that adenosine inhibits anaphylactic histamine release by stimulating adenosine Ri receptors but enhances the release by stimulating Ra receptors. It is also suggested that the inhibition by adenosine of compound 48/80-induced histamine release is not caused by the stimulation of specific adenosine receptors. By either the antagonism at adenosine receptors or the inhibition of phosphodiesterase it seems to be difficult to explain the inhibition by theophylline of compound 48/80-induced histamine release.抄録全体を表示PDF形式でダウンロード (718K) -
細川 敦之, 田辺 正忠, 大川 元臣, 児島 完治, 瀬尾 裕之, 數野 博, 今脇 節朗, 日野 一郎1988 年 100 巻 9-10 号 p. 915-920
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーAngiography of a 53-year-old male suffering from intermittent claudication demonstrated no abnormal finding. US with a 7.5MHZ transducer at the popliteal fossa showed a hypoechoic fusiform area in contact with the left popliteal artery posteriorly. Enhanced CT showed a curvilinear cystic change along the wall of the left popliteal artery posteriorly. A popliteal adventitial cyst was diagnosed preoperatively and confirmed at the time of surgery.抄録全体を表示PDF形式でダウンロード (4159K) -
細川 敦之, 宮本 勉, 松野 慎介, 川崎 幸子, 玉井 豊理, 田辺 正忠1988 年 100 巻 9-10 号 p. 921-926
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーGa-67-scintigraphy was performed on 3 patients with malignant lymphoma of the thyroid. Ga-67-accumulation was noted in the primary lesions of two patients. Ga-67-accumulation was seen in an inflammatory lesion, which was not the primary lesion, in the other patient. One of the patients, who was a 48 year-old woman with primary malignant lymphoma of the thyroid, had metastases in the mediastinum, neck and axillar region. The metastases were clearly detected by T1-201 imaging, but Ga-67 did not accumulate in the metastatic foci. It seems that T1-201 is superior to Ga-67 in defining a primary malignant lymphoma of the thyroid.抄録全体を表示PDF形式でダウンロード (5249K) -
第1編 気管支喘息と末梢血カリクレイン-キニン系の活性化についての検討高井 豊1988 年 100 巻 9-10 号 p. 927-937
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーThe relationship between bronchial asthma and Hageman factor dependent pathways (the contact phase of the internal coagulation system) was studied in reference to the possible role of the kallikrein-kinin system in asthmatics.
The plasma Hageman factor level was significantly lower in asthmatics (74.8±27.7% in remission, and 75.4±26.3% during in attack) than in healthy subjects (98.1±27.6%), and the plasma prekallikrein value was also lower in asthmatics (88.8±25.3% in remission, and 75.1±23.8% during in attack) than in normal controls (105.7±19.7%). Especially, the plasma prekallikrein level was significantly lower in asthmatics during in attack than in those in remission. The plasma bradykinin level of asthmatics in remission tended to be higher (98.8±89.8pg/ml) than that of healthy subjects (47.1±29.6pg/ml). The plasma high molecular weight kininogen level was not significantly different between asthmatics and normal subjects. These results suggest that the plasma kallikrein-kinin system may play a role in the pathophysiology of bronchial asthma.抄録全体を表示PDF形式でダウンロード (699K) -
第2編 気管支喘息患者の気管支肺胞洗浄液上清(BALF)中カリクレイン様活性物質についての検討高井 豊1988 年 100 巻 9-10 号 p. 939-950
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーKallikrein-like activity was evaluated in the bronchoalveolar lavage fluid (BALF) of 43 patients (33 bronchial asthma patients and 10 controls) to study the inflammatory response in the lower respiratory tract of asthma patients.
The appearance rate of BALF kallikrein-like activity (BKLA) was 25.0% in asthmatics, and 60.0% in asthmatics after provocation by a specific antigen, whereas it was negative in healthy subjects. The increase in BKLA in asthmatic subjects was significant. BKLA in patients with an immediate asthmatic response after provocation turned negative, whereas it was positive in their ordinary BALF. On the contrary, BKLA after provocation in those with a late asthmatic response turned positive, whereas it was negative in their ordinary BALF.
Characterization using three protease inhibitors indicated that BKLA had an enzymatic character similar to plasma kallikrein. These results suggest that the activation of the kallikrein-kinin system may have a possible role during anaphylaxis in asthmatics.抄録全体を表示PDF形式でダウンロード (2650K) -
則安 俊昭, 平木 祥夫, 竹田 芳弘, 三村 秀文, 三谷 政彦, 永山 雅子, 木本 真, 加地 充昌, 橋本 啓二, 青野 要1988 年 100 巻 9-10 号 p. 951-957
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーThe results of radiotherapy were investigated in 49 patients with lung cancer admitted to the Department of Radiology, Okayama University Hospital. Of the 26 patients not undergoing surgery, the one-year survival rate was 100% in the stage I patients, 55% in the stage III patients and 56% in the stage IV patients, and the two-year survival rate was 50% in the stage I patients, 0% in the stage III patients and 9% in the stage IV patients. A significant difference in survival between patients irradiated with over 60 Gy and patients irradiated with less than 60 Gy was recognized among those not undergoing surgery. However, with respect to the frequency of local recurrence and distant metastases, a correlation with the irradiated dose was not demonstrated. Local recurrence and distant metastases were not observed in 5 of 6 patients who received preventive irradiation after curative surgery was conducted. Concerning 11 patients after non-curative surgery, local recurrence and distant metastases were recognized in 3 of them, and 7 of them showed a favourable outcome brought about by the irradiation after surgery as expected. In 6 patients with local recurrence after surgery, the survival period after radiotherapy was less than 13 months.抄録全体を表示PDF形式でダウンロード (373K) -
末長 敢1988 年 100 巻 9-10 号 p. 959-970
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーDestruction of articular cartilage of rheumatoid knee joints proceeds by erosion with pannus from periarticular tissues. The subchondral changes, however, are not understood well. In the present study, cartilage with subchondral bone of the patello-femoral joints from 20 rheumatoid knees taken during total knee replacement was examined in sections stained with hematoxylin-eosin and safranin-O, as well as by immunohistochemical techniques (peroxidase anti-peroxidase method).
Alterations of the articular cartilage and subchondral bone plate were graded into 4 stages: A) Partial destruction of the subchondral bone plate, presence of intramedullary granulation tissue, and concomitant decrease in cartilage matrix staining. B) Numerous erosion sites at the osteochondral junction arising from intramedullary granulation tissue. C) Widespread and multiple invasion by the granulation tissue, but cartilage still remaining. D) Almost total loss of cartilage, replaced with granulation tissue.
The osteochondral junction was destroyed by invasion by granulation tissue which proceeded in parallel from both articular cartilage and the intramedullary bone space. Lysozyme was positive on monocytes and fibroblasts at the osteolytic area of the osteochondral junction. S-100 protein was positive on monocytes corresponding to chondrocytes in the same area, where they may take account for lytic function.
It was also confirmed histologically that the subchondral bone has high turnover changes.抄録全体を表示PDF形式でダウンロード (12048K) -
1988 年 100 巻 9-10 号 p. 971-979
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーPDF形式でダウンロード (611K) -
1988 年 100 巻 9-10 号 p. e1
発行日: 1988年
公開日: 2009/03/30
ジャーナル フリーPDF形式でダウンロード (597K)
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