整形外科と災害外科
Online ISSN : 1349-4333
Print ISSN : 0037-1033
ISSN-L : 0037-1033
35 巻, 1 号
選択された号の論文の83件中51~83を表示しています
  • 中村 和輝, 松埼 昭夫, 木梨 博史, 白石 元英
    1986 年 35 巻 1 号 p. 221-223
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    The patient was a 26-year-old student who noticed pain in her left wrist two months before. Local examination showed only tenderness on the anatomical snaff box. Rentogenograms showed a small cyst with slight marginal sclerosis in the carpal scaphoid. Four months later she noticed a soft, smooth, elastic hard, lxlcm mass which could be felt on the volar side of the wrist and wanted to be operated on. A cyst without communication with the wrist joint was found on lateral side of the flex, carp. rad. tendon, extending into the carpal scaphoid through a small window. Extirpation of this cyst contained gelatinous material was done. After curettage of the sclerotic wall, cancellous bone was grafted. Postoperative course was uneventfull. The histological examination of the cyst showed that the lining of the cyst was absent and the wall was composed of collagen fiber. We considered that this case showed extraosseous growth of a intraosseous ganglion of the carpal scaphoid.
  • 呉 哲也, 松尾 隆, 力丸 俊一, 元 豊彦, 多田 俊作
    1986 年 35 巻 1 号 p. 224-229
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    In most cases with spastic paralysis of the upper extremity, the elbow is held in flexion with pronation of the forearm and flexion of the wrist and fingers. Because of this is deformed posture, little effective voluntary control of the hand is possible. From 1979 to 1985, the release operation was performed in eight cases of spastic paralysis and two cases of athetosis. The results of flexor release and associated procedures in this series were demonstrated.
  • 平野 真子, 森沢 佳三, 久保田 健治, 興津 貴則, 益田 郁子, 山鹿 眞紀夫, 津留 隆行, 北川 敏夫, 原田 正孝, 鬼木 泰博
    1986 年 35 巻 1 号 p. 230-236
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    The aim of our study is to demonstrate the result of the functional conditions of shoulder joint and lower extremities in high shool students.
    In our study, we examined 380 high school students (270 males and 110 females). We asked the age, history of sports and injuries of shoulder joint and other regions. In upper extremities, we checked the muscle atrophy of shoulder girdle, the loosening of shoulder joint and anterior, posterior apprehension test. And we evaluated the range and the pain of active motion and muscle strength of shoulder joint. In trunk, we checked back and adbominal muscle strength by modified Kraus-Weber test. In lower extremities, we examined tenderness, patello-femoral angle and the contracture of three muscles-quadriceps, hamstring, and iliopsoas.
    We observed the atrophy and tenderness of trapezius muscle more frequently in the students with much exercise than in ones with little. Most students with tenderness of inguinal or foot region have weakness of back and abdominal muscles.
  • 平塚 弘幸, 河合 尚志, 河合 正行, 井上 喜博, 平野 英二, 朝永 正剛, 相良 耕三, 真子 安二
    1986 年 35 巻 1 号 p. 237-239
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    We have studied the ratio on max. H/M and max. F/M in 20 hemiplegics respectively over the involved and non-involved arms. Each wave was recorded from abductor digiti minimi, and 16 consecutive stimuli were applied to each side of each subject. In 12 hemiplegics with a disused arm, amplitude H/M ratio was found to be significantly higher on the spastic than on the non-involved side. There proved to be a stastically significant association between amplitude H/M ratio and duration H/M ratio (r=0.75, p<0.05). Amplitude F/M ratio was only slightly higher on the spastic than on the normal side. The results indicate that H/M ratio expressed the proportion of anterior motoneuron pool to be excited better than F/M ratio and that 10 consecutive stimuli were enough to get a methodologic convenience.
    The H reflex might play a more important role than the F wave to evaluate as an index of the spastic state.
  • 山本 喜昭
    1986 年 35 巻 1 号 p. 240-245
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Ninety-one cases (81 males, 10 females) of the cervical cord injury were observed the rehabilitation. The patients consisted of seventy-five cases of traumatic injury and sixteen cases of non-traumatic diseases. On the level of palalysis, we observed five cases of C5-quadriplegia twenty-four cases of C6 thirty-three cases of C7 and twenty-nine cases of C8 quadriplegia. After the rehabilitation, fifty-four cases were oneself independent on ADL and eighteen cases had the vocational goal.
  • 脊髄損傷完全麻痺例における
    芝 啓一郎, 佐々木 邦雄, 植田 尊善, 溝口 知行, 前山 叙之, 菊地 哲次郎, 村尾 哲, 吉村 豊暢, 角田 信昭
    1986 年 35 巻 1 号 p. 246-248
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Thirty-six patients with thoracolumbar fractures and complete paraplegia were studied: all patients were treated by combined anterior and posterior approach with double Harrington distraction rods within two weeks of injuries. Harrington instrumentation by square ended rods with segmental spinous process wiring resulted in an earlier rehabilitation which considerably decreased the immobilization and hospitalization time, which were of great psychological importance for the patients.
  • 山鹿 眞紀夫, 北川 敏夫, 高木 克公, 米村 憲輔, 坂田 浩章, 平野 真子
    1986 年 35 巻 1 号 p. 249-252
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Sixty-one cases (sixty-six limbs) of lower extrimity amputation in our clinic were examined from 1975 to 1985. An average age of patients was 44.7 years. Causes of amputation were bone and soft tissue tumors (34 cases, 55.7%), vascular disease (13 cases, 21.3%), burn, trauma and infection etc. (14 cases, 23.0%). Bilateral amputations were performed on 5 cases; 3 cases of vascular disease, one case of trauma and osteomyelitis respectively. Five of 61 cases were impossible to gait on clinical course because of vascular diseases except one with von Recklinghausen disease.
  • 小柳 いく子, 岡元 勉, 北島 隆治, 益川 真一, 忽那 龍雄, 渡辺 英夫
    1986 年 35 巻 1 号 p. 253-257
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Patients with rheumatoid arthritis have various disturbances of activities of daily living.
    We investigated the patients' independency in ward activities of daily living and expected home activities of daily living.
    According to the result of our investigation, we made several kinds of self-help devices.
    For example, devices for eating, dressing, grooming, handwriting, sitting up, toileting, bath room transter and etc. were made for our rheumatoid arthritis patients.
  • 内藤 正俊, 泊 真二, 黒木 健文, 合屋 忠信, 阿部 哲哉, 藤永 隆, 佐々木 春彦
    1986 年 35 巻 1 号 p. 258-260
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Five dialysis patients are described in whom symptoms of suprascapular nerve entrapment neuropathy developed with an average of 104.6 months after the formation of the fistula. The cardinal findings included pain in the shoulder, weakness and wasting of spinati muscles, and prolonged motor latencies of the suprascapular nerve to the spinati muscles. The transverse scapular ligament release was performed in all of our patients with relief of pain. The etiology of the entrapment neuropathy in dialysis patients is discussed.
  • 松永 英裕, 城戸 正喜, 権藤 英資, 田中 幹夫, 竹下 満, 高岸 直人
    1986 年 35 巻 1 号 p. 261-264
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    We recently experienced three cases of suprascapular nerve palsy and all cases were treated by operation. The causes of three cases of suprascapular nerve palsy were as follows; the case 1 by entrapment neuropathy, the case 2 by ganglion cyst and the case 3 by sports injury.
    The causes of nerve palsy and the diagnosis were discussed.
  • 高畠 一雄, 内田 芳雄, 小島 哲夫, 大木 實
    1986 年 35 巻 1 号 p. 265-268
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    We report a case of ulnar nerve palsy with multiple lesions. A fifty-six-year-old man was admitted due to intrinsic muscle atrophy of the right hand and hypesthesia of the ulnar two fingers. Preoperative examination revealed three lesions; cervical spine, cubital tunnel and the canal of Guyon. We found marked degeneration of the ulnar nerve at the elbow, and furthermore, an anomalous muscle in the canal of Guyon. The ulnar nerve was compressed by this muscle in this canal. This muscle originated from palmaris longus tendon and attached to hypothenar muscle.
    Preoperatively, it was difficult to determine the main lesion of the ulnar nerve, In EMG examination, there were delayed terminal latency at the canal of Guyon and decreased MCV at the elbow joint. Electrophysiological examination was very useful to decide an operation field.
  • 堀 司郎, 杉村 功, 村岡 博, 立川 勝司, 黒木 秀尚
    1986 年 35 巻 1 号 p. 269-273
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    We report two cases of ulnar nerve neuropathy caused by an intraneural ganglion of the cubital tunnel. At operation these ganglions were located between the nerve fibers and had a stalk extending to the medial joint capsule of the elbow. The stalk and cyst were removed under the operating microscope and King's method was done. Two cases' progress was very good. The microscopic specimens from the excised tumor were that of a ganglion. We discuss about the origin of ganglion, whether it is an intraneural or extraneural cyst.
  • 南崎 剛, 折戸 隆, 森本 兼人, 古瀬 清夫, 前山 厳
    1986 年 35 巻 1 号 p. 274-276
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    We experienced a rare case of the ulnar nerve palsy caused by the compression of the cyst arising from the flexor carpi ulnaris fascia.
    The patient was a 60 years old male and had hypesthesia at the right ring and little fingers. The ulnar nerve was compressed by the cyst which was multilocular, 11.5×4.0×3.0cm in size and contained yellow jelly fluid. This cyst arouse from the flexor carpi ulnaris fascia near the medial epicondyle and there could not be found any comminucation with the joint capsule.
    Microscopically, the cyst wall was composed of dense collagen fibers and no muscle fibers were seen.
  • 二次的神経縫合
    桜井 治彰, 鈴木 勝己, 伊地知 正光, 永田 善之, 三浦 直彦, 鶴上 浩
    1986 年 35 巻 1 号 p. 277-280
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Although the repairments of the peripheral nerve have been developed in cases recently, there are some controversies over the timing of the secondary repairment. We have experienced 14 cases (18 nerves) of secondary repairment of divided peripheral nerve injuries. There are 5 nerves of the ulnar nerve, 3 of the median nerve, 2 of the radial nerve and 8 of the digital nerve. All cases were sutured with epineural suture microscopically, and these postoperative results were evaluated by using Heighet's criterion and the static two-point discrimination method. No significant differences were observed between the timing before and after 3 month from the initial injuries. However, neuromas and relative big scars at the nerve stumps were observed in the cases which repair was performed after 3 months. We suggest that the large gap should be avoided, so the timing of secondary repairment is better within 3 months after injuries.
  • 白石 元英, 松崎 昭夫, 木梨 博史, 城戸 正喜
    1986 年 35 巻 1 号 p. 281-283
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    An operated case of entrapment neuropathy of the common peroneal nerve is presented. In this case taut lateral tendinous portion of proximal part of the peroneus longus seemed to be the cause. Symptomatology, differential diagnosis and treatment of this disorder are discussed. The authors emphasized that this probably underrecognized disorder has to be differentiated from the condition that shows pain and sensory disturbance in the leg and foot.
  • 倉信 耕爾, 上平 用, 大月 健二, 林 正郎, 森尾 泰夫
    1986 年 35 巻 1 号 p. 284-288
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Ten patients of tarsal tunnel syndrome had been treated by surgical decompression of the posterior tibial nerve. The causes of compression were ganglion, fascia, retinaculum and fat tissue. The postoperative clinical features of nine patients were better more than fair. As seven cases had been suffered from lumbar spine disease at the same time, it was difficult to diagnose tarsal tunnel syndrome and asses postoperative clinical features.
  • 山本 裕之, 井原 秀俊
    1986 年 35 巻 1 号 p. 289-293
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    To evaluate the accuracy of positive single contrast arthrography for assessing the status of the anterior cruciate ligament (ACL) and the posterior cruciate ligament (PCL), we reviewed retrospectively 41 arthrograms of normal ACL and normal PCL, which were examined by injury mechanism, clinical findings and/or arthroscopy, 30 arthrograms of injured ACL and 15 arthrograms of injured PCL which were examined by arthroscopy or arthrotomy. Using our criteria for evaluation of radiographic appearance, normal ACL arthrograms were subdivided into 2 groups, abnormal ACL arthrograms 3 groups, normal PCL arthrograms 2 groups and abnormal PCL arthrograms 1 group. The results were analysed to determine sensitivity, specificity and diagnostic accuracy etc.. The first, the second and the third 96.7%, 95.1%, and 95.8% respectively in ACL and 46.7%, 90.2%, and 78.6% respectively in PCL.
  • 松永 俊二, 貴島 稔, 田中 信次, 萩原 浩
    1986 年 35 巻 1 号 p. 294-297
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    This study reports on the disability of 33 patients with chronic laxity of anterior cruciate ligament treated conservatively. All patients were evaluated at average of 3.2 years after injury. There was high incidence of functional disability and secondary meniscal tears in athletically active individuals. But 22 patients (85%) had no disability for overall routine activities of daily living.
    So we concluded from this follow-up study that athletically active individuals who are unwilling to modify sports participations need operative treatment but other patients can be treated satisfactorily without operative procedure.
  • 緒方 公介, 福島 一彦, 杉岡 洋一
    1986 年 35 巻 1 号 p. 298-301
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Using normal cadaver knees from adults, we studied the functional importance of the sites of attachments of the anterior cruciate ligament on the lateral femoral condyle as determinants of the length of the ligament at different amounts of knee flexion. The distance between the central point of the normal attachment area on the tibia and the point slightly proximo-medial to the normal central point on the femur was found to be most isometric with the full range of knee motion. We also studied the biomechanical strength of the two types of the patellar tendon graft (one, a free tendon, and the other, a tendon with its bone insertions at both ends), and found that the bone-tendon preparation achieved stronger fixation to the bone in earlier postoperative time than the free tendon.
    Between 1981 and 1984, we performed the anterior cruciate reconstruction on 27 patients using the patellar bone-tendon-bone graft. Results were analyzed on 15 patients who were followed for more than one year postoperatively. Eighty per cent of these patients showed excellent or good results. Objective results were better in the patients who had an extra-articular augmentation procedure than in those who had no augmentation.
  • 今村 正純, 直野 敬, 藤本 祥治, 諫山 哲郎, 小野 正彦, 頼 輝助, 高見 博昭
    1986 年 35 巻 1 号 p. 302-304
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Since 1975, we have carried out reconstruction of the ligamentous injuries of the knee in twelve cases. Good results have been obtained in six cases which showed functional insufficiency. With combined injury, poor results have beenobtained.
  • 田村 裕昭, 内田 和宏, 山崎 康弘, 田中 道治, 川嶌 真人, 井原 秀俊
    1986 年 35 巻 1 号 p. 305-310
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Single contrast arthrographic technique is not so popular in Japan. We performed this technique on about 100 patients and meniscus lesions of 45 patients among them were confirmed using the arthroscopy or surgery. The sensitivity of this technique was 91.2% and specificity was 92.6%. We convinced that this technique was very useful for the diagnosis of meniscus lesion. So we reported the procedure and utility of this technique.
  • 山本 裕之, 井原 秀俊
    1986 年 35 巻 1 号 p. 311-316
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    As to treatment of meniscal tear, meniscal repair is shown to be an attractive therapy in comparison with meniscectomy if considering meniscus function in human being such as loadbearing and a second restraint etc.. It is difficult to investigate the postero-medial corner knee joint by arthroscopy, but it is easy to find meniscal tear in it by arthrography. For 4 cases with longitudinal tear of middle and posterior segments of medial meniscus combined with ACL injuries, we performed positive single contrast arthrography before and after meniscal repair. We could find meniscal tear accurately in all cases arthrographically. On the other hand we could suspect meniscal tear in only 2 cases arthroscopically. After repair we found arthrography to be useful for determining repaired meniscus to be healed.
  • 緒方 公介
    1986 年 35 巻 1 号 p. 317-318
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Arthroscopic meniscectomies were performed on 76 cases between June 1983 and September 1985. The average age of the patients at the time of surgery was 30 years (range, 7 to 62 years). Meniscectomies included 31 cases of medial meniscus, 28 lateral meniscus and 18 lateral discoid meniscus. The 30 degrees arthroscope alone was sufficient for most cases. The TV monitor was valuable, but of no absolute necessity. Most useful instruments were the banana-blade knife, curved basket forceps and pituitary rongeur. Seventy-six per cent of the patients showed excellent results at follow-up of more than 6 months. The major advantage of arthroscopic meniscectomy was easy postoperative rehabilitation and early return to activities of daily living for the patients.
  • 大田 秀樹, 緒方 公介, 田所 英二, 津村 弘, 片井 憲三
    1986 年 35 巻 1 号 p. 319-322
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    The pathogenesis of osteochondritis dissecans of the distal femur has been a controversial subject. We present two cases with osteochondritis dissecans of the lateral femorol condyle which were associated with lateral discoid menisci. The first case was a 17-year-old female who had had slight pain in her left knee since she was 8 years old. She had severe pain after direct blow to her left knee. Radiographs showed osteocartilaginous body in a subarficular location within the left lateral femoral condyle posteriorly. An arthrogram showed lateral imcomplete discoid meniscus. The second case was an 11-year-old female who had complete excision of the left lateral complete discoid meniscus four years ago. Three years postoperatively, she had severe pain in her left knee after gymnastic exercises. Radiographs showed osteochondrific lesion on the lateral femoral condyle. At surgery, curettage and fixation of the osteochondral fragment with autogenous bone pegs were performed for the first case, and bone peg fixation only for the second case.
  • 坂本 央, 緒方 公介, 一矢 有一, 福島 一彦
    1986 年 35 巻 1 号 p. 323-326
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Thirteen patients with gonalgia who had no definite cause of pain, including nine women and four men ranging in age from fourteen years to seventy-two years, were investigated by 99mTc-MDP bone scintigrams. There were seven patients with osteonecrosis and six patients with reflex sympathetic dystrophy (RSD). It is suggested that scintigraphic findings are correlated with the clinical symptoms.
  • 泊 一秀, 鳥巣 岳彦, 藤原 亨
    1986 年 35 巻 1 号 p. 327-331
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Supracondylar fracture of the femur following total knee arthroplasty is a serious complicatication. Treatment of these fractures is controversial and difficult because of the presence of bone cement and prosthetic components. A 75-year-old woman, who had been treated with bilateral total knee arthroplasties, fell on the knee and sustained supracondylar fracture of the left femur. Skeletal traction was applied for one month and plaster cast was done for another month. However, sound healing of the fracture could not be obtained. Revision of the arthroplasty was carried out by use of a femoral component with a metal rod to stabilize the fracture.
  • 頼 輝助, 直野 敬, 藤本 祥治, 今村 正純, 小野 正彦, 諫山 哲郎, 高見 博昭
    1986 年 35 巻 1 号 p. 332-335
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    A 24 years old female with recurrent idiopathic hematoma in the isolated suprapatellar pouch of the knee was treated in our clinic. Her chief complaint was extensive swelling at the region just proximal to the patella during the last 3.5 months, and recently she felt pain about the knee after long time of upright sitting. She had no evident history of trauma.
    The hematomacyst, which was isolated from the knee joint cavity by a thin membrane and covered by a capsule of 2mm thickness, was resected. It was diagnosed as bursitis histologically. There was no recurrence at 5 months after operation.
  • 森元 保, 柚木 紘一郎, 橋口 兼久, 脇丸 一孝, 米盛 学, 松本 玲子, 増田 明敏
    1986 年 35 巻 1 号 p. 336-338
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Many cases of pigmented villonodular synovitis (P. V. S.) have been reported. But P. V. S. is not likely to be diagnosed in early stage. We experienced a case of P. V. S. of the early stage with a plica synovialis mediopatellaris (shelf).
    The patient was a 16-year-old girl, who had suffered from arthralgia and effusion (not bloody) with occasional locking and giving way in the left knee joint for two years.
    Radiogram showed normal findings. Arthrogram revealed a shadow of shelf plica in the medial side of the knee. Through the arthroscopy an incomplete shelf and an abnormal synovial mass were found in the medial compartment. We performed surgical excision of the shelf and the mass (6cm×2cm), which included some nodules. The diagnosis of P. V. S. was made at surgery and was confirmed histologically.
    The patient had an uneventful postoperative course and was free of symptoms eight months after surgery.
  • 山徳 義郎, 有富 寛, 飯塚 健児, 大野 司
    1986 年 35 巻 1 号 p. 339-344
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    we performed arthroscopic synovectomy with electric resectoscope for 10 patients whose knee hydrarthrosis had persisted for longer than 6 months. Clinical follow-up examination revealed much more satisfactory results, compared with those in rheumatoid arthritis.
    This technique is very effective for nonrheumatic hydrarthrosis. In addition we would like to advocate the advantage of electric resectoscope.
  • EHDPくる病ラットに対する影響
    川村 秀哉, 江口 正雄, 柴田 堅一郎, 和田 文夫, 島内 卓, 中島 勝也, 井樋 直孝
    1986 年 35 巻 1 号 p. 345-350
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    In 1984, Minne et al. reported the hypocalcemic effect of imidazole in rats. And so, Moncada and Needleman (1977) had reported that imidazole inhibits bone resorption in vivo and in vitro. Now, imidazole is known as an activator of adenosine-3′, 5′-phosphodiesterase which is the enzyme that degrades cyclic AMP.
    We are interested in the drug's effect on calcification in vivo. We investigated the effect of imidazole in rickets rats induced by EHDP. A short time and high dose EHDP inhibits the calcification of growth plates at proximal ends of rats tibia. Imidazole promoted the calcification of those growth plates in dose responsively.
  • 新井 堅, 貝原 信紘, 高岸 憲二, 佛淵 孝夫, 有田 親史
    1986 年 35 巻 1 号 p. 351-353
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    Immunization of rats with native bovine type II collagen results in a polyarthritis in approximately 90% of the rats. Using an enzyme-linked immunosorbent assay, IgG antibodies to type II collagen in serum and paw tissue were measured as total IgG and as its subclasses (IgG1, IgG2a, IgG2b, IgG2c) in arthritic and non-arthritic rats. Anticollagen IgG subclass analysis revealed that the major subclass was IgG2a in both the serum and paw extract, with minor amounts of IgG2b, IgG2c and IgG1. Serum levels of anticollagen IgG2a in arthritic rats were significantly higher than those of non-arthritic animals. The significance of these results and their possible relevance to human disease are discussed.
  • Histologic Grading について
    佛淵 孝夫, 貝原 信紘, 高岸 憲二, 新井 堅
    1986 年 35 巻 1 号 p. 354-357
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    As a skeletal tissue allograft model, limb allografts with or without Cyclosporin (CS) treatment using three inbred rat strains, Fischer (F344; RT11), Lewis (LEW; RT11) and Brown Norway (BN; RT 1n), were performed, and we graded the degree of rejection according to the categories by Fritz.
    In minor-mismatched allografts (LEW→F344), clinical and histologic examinations revealed no signs of rejection 16 weeks after operation with the use of CS, whereas, without CS treatment severe degeneration and necrosis of the grafts were shown by 16 weeks.
    In major-mismatched allografts (BN→F344), histologic examination revealed that rejection in CS-treated recipients did not appear as typical rejection, but only as a mild skin rejection, even though rejection appeared complete by gross visual observation of the skin 16 weeks after operation. While the grafts without CS treatment were degenerated and destructed by 6 weeks.
    Our results indicate the possibility of clinical application of skeletal tissue allografts with the use of CS as well as other organ transplantations.
  • 林 和生, 松口 信行, 中川 悟, 杉岡 洋一, 金丸 孝昭, 北村 安弘
    1986 年 35 巻 1 号 p. 358-363
    発行日: 1986/10/25
    公開日: 2010/03/16
    ジャーナル フリー
    The question of material is central to all considerations on the development of a cementless skeletal implant system that has a long-term stalility. However, it would be presumptuous to assume that lifeless matter can mimic perfectly function and skeletal properties of living bone-especially when the selection is limited to single materials. So we are trying to make a new orthopaedic material which is not brittle but has a good biocompatibility, and non-corrosiveness. The α-Al2O3, γ-Al2O3, TiN, HAP ceramics were chosen to coat stainless steel. These materials were inserted in the femurs of adult dogs, The results showed that the stainless steel screws coated with α-Al2O3 and ones with HAP had a excellent biocompatibility.
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