岡山医学会雑誌
Online ISSN : 1882-4528
Print ISSN : 0030-1558
81 巻, 3-4 号
選択された号の論文の14件中1~14を表示しています
  • 第1報 亜硫酸ガス濃度と風向,風速,大気安定度との関係
    井上 堅太郎
    1969 年 81 巻 3-4 号 p. 127-134
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    The author calculated the frequency of high concentration of sulfur dioxide (over 0.2 p. p. m.) in one hour according to wind direction, wind velocity and Pasquill's stability, and the author also calculated the average concentration of sulfur dioxide according to wind direction and velocity.
    The results obtained were as follows;
    1. S, SSW, SW, and WSW winds (mainly sea breeze) bring the air pollutant to the northern part in Mizushima Industrial Area. Wind direction and wind velocity that brings. a higher concentration of sulfur dioxide to Fukuda-cho, Minami Kasuga-cho, and Amagi were S, SW, and SSW winds of 3-4 M/sec. In Mizushima Harbour Office, high sulfur dioxide concentartions were measured in S, SW, 2-3 M/sec. and SW, 2-5 M/sec. Average sulfur dioxide concentrations were higher in S, SW, 2-4 M/sec. in Fukuda-cho, Minami Kasuga-cho and higher in SSE 6 M/sec., SSW 6-7 M/sec., SW 2-5 M/sec., and S 3 M/sec. in Mizushima Harbour Office.
    2. Unstable sea breeze brings higher concentrations of sulfur dioxide to Fukuda-cho and more stable sea breeze brings higher concentrations to Amagi.
    From the calculations of diffusion by Pasquill's chart it was shown that the diffusion in C-stability brings high concentrations of sulfur dioxide to Fukuda-cho, and the diffusion in D-stability brings to Amagi.
  • 高原 滋夫, 小倉 義郎, 小山 高司, 岸本 浩之, 千葉 和夫, 貞本 昌規, 竹久 亨, 三谷 恭夫, 黒田 泰生, 笠井 英夫, 大 ...
    1969 年 81 巻 3-4 号 p. 135-141
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    The authors reported the results of field survey and family follow-up on acatalasemia and hypocatalasemia during the years of 1966 and 1967.
    Thirty-seven hypocatalasemias were seen in the tests of 11, 875 individuals at Chiba Prefecture including the examinees tested in 1965. Thus, the rate of incidence at Chiba amounted to 0.31%.
    The test on students of Okayama University revealed two hypocatalasemias among 2, 526 (0.08%).
    Oki Is. contained seven hypocatalasemias among their 4, 831 school-children. And no hypocatalasemic individuals were found out among 2, 682 inhabitants of Okinawa Is., Ryukyu.
    Formosa, however, showed rather high incidence rate such as 0.28%, 60 hypocatalasemias among 21, 789 inhabitants.
    In 1966 and 1967, three acatalasemias of two families, one of them already reported in 1965, were added to the formerly known cases.
    Consequently, the total of reported acatalasemias were 93 cases of 44 families by the end of 1967.
  • 第II編 X線誘発RFマウス白血病におけるウイルス粒子の電子顕微鏡的証明
    岡田 直子
    1969 年 81 巻 3-4 号 p. 143-150
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    Electromicroscopic studies on the lymph nodes of RF mice with X-ray induced leukemia revealed in intercellular spaces round virus particles, 100 mμ in average diameter, each consisting of an outer membrane and a nucleoid body. They belong to C type virus particles according to the classification of oncogenic viruses by Bernhard, et al or Hiraki, et al.
    The virus particles showed an identical morphology and process of formation with those of spontaneous leukemic virus. This present report combined with successful implantation of cell-free filtrate from leukemic mice reported in the previous paper gives firmer ground to the idea that inactive virus latent in normal RF mice through vertical transmission was activated by X-ray to act on normal cells to transform into leukemic cells.
  • 第1編 特に血液学的面よりの考察
    角南 重夫
    1969 年 81 巻 3-4 号 p. 151-160
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    The health survey of peasants and fishermen were carried out in 1968 at two districts. The one is T-area which has a charactor of a farm village. The other is K-area which has that of a fishing village. Farm houses from both T-area and K-area and fishing houses from K-area were sampled. Farm houses sampled from T-area is abbreviated as T and fishing houses sampled from K-area as K1 and farm houses sampled from K-area as K2. The blood examinations of peasants and fishermen were conducted for this health survey. The specific gravity of the blood, the density of the serum protein, the hemoglobin level and the concentration of the serum iron were measured.
    1) No significant differences exist between the means of the specific gravity of blood of the husband in K1 and T, and also between that in K2 and T, and so do among that of housewife in K1, K2 and T.
    2) Significant differences exist between the means of the density of serum protein of husband in T and K1, and so do between that of T and K2.
    3) Considering from the point of means and ratio of people whose blood is abnormal against people examined. Following results were oftained. The specific gravity of the couple in T is better than that of the couple in K1 and K2. The density of serum protein of the couple in K2 is better than that of the couple in T and K1. The hemoglobin level of the couple in K1 is better than that of the couple in T and K2.
    4) It is recognized that about fifty per cent housewives have serum iron deficient anemia.
    5) I devised the nomogram showing differences of patterns which indicate the values of the blood specific gravity, the hemoglobin level, the density of the serum protein, and the concentration of the serum iron, in the inhabitants of the different areas. This monogram has a convenience that we can easily detect whether mean obtained from blood test show over standard level or not at a glance.
    6) The hemoglobin level correlate with the specific gravity in the blood of husband in T (γ=0.89). Correlation can be found in the case of housewife in T (γ=0.96).
    7) The Hemoglobin level of husband correlates with that of housewife (γ=0.51).
    8) It is recognized that the ratio of family in which both husband and wife indicate low value of blood examinations against total family number indicating low value of blood examinations shows high value (70 per cent in T).
  • 第1編 胃液乳酸脱水素酵素活性について
    高田 徹
    1969 年 81 巻 3-4 号 p. 161-167
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    Measurement of lactic dehydrogenase activity of basal gastric juice was attempted in order to evaluate the validity of the method as a tool for the diagnosis of various gastric disorders. The activity, however, was found to show a remarkable decrease in gastric juice with a PH below 6.0 forthis reason, intragastric neutralization with 3.5% sodium bicarbonate solution was performed in the present work. Patients consist of 12 cases of gastric cancer, 11 of chronic gastritis, 8 of benign peptic ulcer, and 8 of normal controls. Specific activity of LDH in normal controls ranged 1 to 10 units per milligram of soluble protein, with a mean value of 4. It ranges 1 to 13 with a mean value of 4 in benign peptic ulcer, 5 to 25 with that of 14 in chronic gastritis, and 8 to 74 with that of 25 in gastric cancer. The results indicate that the specific activity of LDH in gastric juice is specifically elevated in gastric cancer and somewhat less in chronic gastritis, and that the method may be used as one of supplementary diagnostic tools of gastric cancer.
    Furthermore, it is suggested that the elevated specific activity of LDH in gastric cancer and chronic gastritis might have derived from the identical origin.
  • 第2編 胃液乳酸脱水素酵素アイソザイムについて
    高田 徹
    1969 年 81 巻 3-4 号 p. 169-176
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    The previous report showed that the specific activity of Lactic dehydrogenase was significantly elevated in gastric juice of chronic gastritis and gastric cancer. In addition, the possibility was proposed that chronic inflammation of gastric mucosa in both disorders might have contributed to the elevation of activity. In the present work, isoenzymatic studies were performed with electrophoresis and histochemical examination in order to elucidate the origin of the LDH activity found in gastric juice.
    LDH isozymes of human gastric juice are characterized by predominance of LD(I) and a gradual decrease of activities towards the cathode, showing no difference in patterns among normal controls and various gastric disorders, such as chronic gastritis, gastric ulcer and gastric cancer. The results indicate that the origin of LDH activity of gastric juice is identical, and locate at some specific mucosal cell or cells. Histochemical studies were performed in order to spot the locali ation of LDH in gastric mucosa at cytological level. According to Kaplan's report, chicken heart muscle LDH (mostly H type) was stable, whereas skeletal muscle (mostly M type) lasts its activity when exposed to 55°C for 10 minutes. Thus gastric mucosal frozen sections mounted on slides were incubated at 55°C for 10 minutes, and then histochemically stained. LDH activity was found to remain in parietal cells alone. It is suggested from the above experiment that LDH in parietal cell is mostly of H type, and LDH in other cells (mucosal epithelial cells, chief cells, intestinal metaplasia and other cells) mostly of M type, and that LDH in gastric juice is probably derived from gastric mucosal cells other than parietal cells. Many invastigators have histochemically shown an increased LDH activity in mucosal epithelial cells in chronic in-flammation and in intestinal metaplasia. It is known however that the numbers of parietal cells and chief cells are decreased in chronic inflammation. Consequently the elevated LDH activity of gastric juice in chronic gastritis and gastric juice in chronic gastritis and gastric cancer is thought to be from mucosal epithelum and intestinal metaplasia.
  • 第1編 血清および臓器低密度リポタンパクの脂質について
    岡村 進介
    1969 年 81 巻 3-4 号 p. 177-186
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    Low density lipoprotein in Ehrlich tumor bearing mice was studied on lipids in serum and Organs, and which were compared with those of normal mice by means of disc electrophoresis, biochemical analysis and thin-layer chromatography. The mobility of tumor bearing mice low density lipoprotein (L D L) in electrophoresis was smaller than that of normal mice L D L. The quantity of phospholipid to protein was decreased in tumor bearing mice L D L than normal.
    The ratio of phospholipid to cholesterol in serum and liver was decreased in tumor bearing mice than normal. On the structure of phospholipids, the content of lecithine in tumor bearingmice L D L reduced by half than normal.
  • 第2編 血清および肝低密度リポタンパクのステロイド代謝について
    岡村 進介
    1969 年 81 巻 3-4 号 p. 187-191
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    Low density lipoprotein in Ehrlich tumor bearing mice was studied on the cholesterol conversion to steroid hormone in serum and liver, and which were compared with those of normal mice by means of thin-layer chromatography and radioactivity. 3H-cholesteryl ester was completely formed by 6 hours after the 3H-cholesterol administration from peritoneal cavity. The most part of the cholesterol was esterified and incorporated into lipoproteins.
    The metabolic processes were studied in Ehrlich ascites carcinoma bearing mice. The cholesterol conversion to steroid hormone in tumor bearing mice L D L was elevated twice to four times than the normal.
  • 第1報 異臭魚の分布状況について
    三宅 与志雄
    1969 年 81 巻 3-4 号 p. 193-197
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    The distribution of abnormal odor fish owing to industrial waste water from oil or its combinative industrial factories around the Miziushia waters was surveyed and the followings were obtained as the result.
    1) It was found that almost all of abnormal odor fishes in the Migushima waters grow around the Mizushima harbour where many exits of industrial waste water from factaries are gathered.
    The area of the distribution is beconing more extensive with the degree of 1 or 2Km. every year, and it has stretched 8Km. to the south and 12Km. to the west around the Mizushima harbour.
    2) Fishes having the high swimmung activity (ex. common sea-bass, gizzard shad and gray mullet etc.) were found as abnormal odor fishes as far as the border of the distribution area, and fishes having the low activity (ex. rock, bleak sea-bream and surf-fish etc.) were found within 1Km. from the mouth of the harbour. And the following is thinkable that fishes gather to the warm water of the Mizushima harbour owing to the high temperature of waste water of factaries and there become abnormal odor fishes, and in spring when water becomes warm, they scatter away from the harbour.
  • 第1編 悪性リンパ腫及びその類縁疾患に於けるリンパ系造影法の臨床応用
    神原 紘司
    1969 年 81 巻 3-4 号 p. 199-219
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    The clinical significance of lymphography is discussed through experiences of 34 cases of malignant lymphomas and allied diseases; 7 cases of lymphosarcoma, 5 cases of reticulosarcoma, 11 cases of Hodgkin's diseases 5 cases of giant follicular lymphoma, 4 cases of unclassifiable malignant lymphoma, and 2 cases of macroglobulinemia.
    1) Lymphosarcoma
    The enlarged lymph nodes in lymphosarcoma are well defined but there may be partial filling defects. The internal structures are finely or coarsely reticular.
    2) Reticulosarcoma
    The lymphogram also reveals a distinct margin. The internal architecture appears like honeycomb, finely dotted or coarsely reticular and often shows diffuse filling defects.
    3) Hodgkin's disease
    The lymph node appearance is characteristic. The border remains distinct but has irregular marginal dotted filling defects, and the internal pattern is coarsely dotted and often shows moth-eaten or punched out filling defects. Sometimes, linear cystic appearance is found.
    4) Giant follicular lymphoma
    The lymphogram of giant follicular lymphoma is not pathognomonic and eventually may present a sarcoma-like appearance.
    5) Macroglobulinemia
    The border remains intact. The internal pattern of the lymph nodes is coarsely dotted or may be later reticular and in some areas follicular filling defects are seen. It may be stated that characteristic lymphographical pictures are recognized for typical cases. But sometimes these findings overlop each other and the x-ray findings are not pathognomonic.
    Therefore, it is difficult to make an accurate diagnosis on the, type of malignant lymphomas. However, we can differentiate those from the inflammatory and metastatic patterns.
    Lymphography in malignant lymphomas and allied diseases is very important for the diagnosis of the localization and spread of the disease. Especially, in the abdominal type, lymphogram is of definitive value. Furthermore, this method is useful for the search of progression and understanding of therapeutic effects.
  • 第2編 白血病におけるリンパ系造影法の臨床応用
    神原 紘司
    1969 年 81 巻 3-4 号 p. 221-233
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
    Lymphography has been performed in 46 patients with leukemia and the common distinctive features are evaluated. There is a general increase in the size and number of the lymph node.
    Their outline is well-defined and saucer-shaped and their internal pattern is coarsely dotted. Lymphographically, there is no significant difference between myeloid leukemia and lymphatic leukemia. Sometimes, the lymph nodes in chronic lymphatic leukemia are gigantic and the internal basophilic is frothy (écumeux) or fantomatique. The internal pattern of the lymph nodes in chronic myeloid leukemia and acute myeloid leukemia presents a similar finding and that in monocytic leukemia, basophilic leukemia and erythroleukemia is not specific. Although there is no pathognomonic finding for each form of leukemia, the leukemic patterns are certainly different from those of normal, inflammatory or metastatic lymph nodes.
    Lymphography also is useful for the detection of leukemic involvement of the deep-seated lymph nodes, and allows sequential observations or their size changes following therapy.
    The side effects of lymphography include a transiert fever and pulmonary embolism, but serious untoward reactions are rare. The author experienced 3 patients with clinical signs compatible with pulmonary embolism and 17 cases of fever among 76 cases examined. However, there was no mortality and fever was preventable by intravenous injection of 30 mg of predonisolone. The peripheral blood pictures showed no significant changes. As a systemic reaction iodine anaphylaxy is reported but there is no such drug reaction in the present series.
  • 1969 年 81 巻 3-4 号 p. 235-241
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
  • 1969 年 81 巻 3-4 号 p. 241-245
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
  • 1969 年 81 巻 3-4 号 p. 245-250
    発行日: 1969/04/30
    公開日: 2009/08/24
    ジャーナル フリー
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