巻号一覧
71 巻 (1959)
- 12-2 号 p. 8243-
- 12-1 号 p. 7861-
- 11supplement 号 p. 1-
- 11-2 号 p. 7531-
- 11-1 号 p. 7095-
- 10-2 号 p. 6691-
- 10-1 号 p. 6223-
- 9-2 号 p. 5773-
- 9-1 号 p. 5405-
- 8-2 号 p. 4993-
- 8-1 号 p. 4515-
- 7-2 号 p. 4069-
- 7-1 号 p. 3623-
- 6-2 号 p. 3149-
- 6-1 号 p. 2783-
- 5-2 号 p. 2423-
- 5-1 号 p. 1989-
- 4-2 号 p. 1655-
- 4-1 号 p. 1145-
- 3supplement-2 号 p. 1-
- 3supplement-1 号 p. 1-
- 3-2 号 p. 1145-
- 3-1 号 p. 691-
- 2-2 号 p. 691-
- 2-1 号 p. 323-
- 1 号 p. 1-
前身誌
93 巻, 7-8 号
選択された号の論文の11件中1～11を表示しています
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第1編 慢性関節リウマチのコラゲナーゼ活性ならびにモノアミンオキシダーゼ活性について戸田 俊介1981 年 93 巻 7-8 号 p. 643-656
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーWe assayed the activities of collagenase and monoamine-oxidase (MAO) in the fluid of the patients with rheumatoid arthritis (RA) and examined the relationship between collagenase, MAO activities and the grade of joint inflammation. The mean collagenase value of RA patients was significantly higher than that of osteoarthritis (OA) patients. A significant positive correlation was present between collagenase activity, leukocyte counts, and beta-glucuronidase activity in RA synovial fluid. These indices are considered to be parameters of the grade of joint inflammation. There was no correlation between collagenase activity, erythrocyte sedimentation rate (ESR), gamma-globulin level, Creactive protein (CRP), rheumatoid factor, acid-phosphatase activity and the stage of RA (grade of joint destruction). The mean MAO value of RA synovial fluid was significantly higher than that of OA synovial fluid. The mean activity of the group of patients whose CRP values were below two positive was significantly higher than that of the group of patients whose CRP values were over two positive. The mean MAO activity in stage 3 or 4 group was significantly higher than that in stage 1 or 2. These findings suggest that collagenase activity is intimately correlated with the grade of local Inflammation in RA and that the MAO activity is closely correlated with the grade of joint fibrosis.抄録全体を表示PDF形式でダウンロード (2464K) -
第2編 慢性関節リウマチの経過とコラゲナーゼ活性戸田 俊介1981 年 93 巻 7-8 号 p. 657-666
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーWe examined the relationship between collagenase activity and the clinical course of the patients with rheumatoid arthritis (RA). The activity of active and inactive collagenase (treated by 3M-KI) was assayed several times for synovial fluid from twelve RA patients and one patient with osteoarthritis (OA). Rheumatoid factor, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), leukocyte counts and acid-phosphatase activity in the synovial fluid were measured simultaneously. In seven of twelve cases, the change of inactive collagenase activity was parallel by changes in synovial leukocyte counts or acid-phosphatase activity. In five of seven cases, the change in inactive collagenase activity was paralleled by acid-phosphatase activity and leukocyte counts. These findings suggest that collagenase activity is intimately correlated with the grade of local inflammation of RA and that the change of collagenase activity is closely correlated with the clinical course of RA patients.抄録全体を表示PDF形式でダウンロード (457K) -
第1編 気管支肺胞洗浄法による気管支喘息の病態に関する研究竹山 博泰1981 年 93 巻 7-8 号 p. 667-683
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーCytological studies were performed on bronchoalvelar lavage (BAL) fluid in 40 cases with bronchial asthma. The results were as follows.
1) In 13 healthy subjects the cells in BAL fluid comprised 89.6% macrophages, 9.7% lymphocytes, 0.7% neutrophils, 0.4% eosinophils and 0% basophils.
2) In asthmatic cases the cells in BAL fluid comprised 54.4% macrophages, 12.6% lymphocytes, 11.8% neutrophils, 21.2% eosinophils and 0.1% basophils. These cases showed a marked increase in the number of eosinophils and a moderate increase in the neutrophil count as compared with healthy subjects. The increased number of eosinophils in lavage fluid was relatively closely related to positive immediate skin tests, high serum IgE levels and peripheral eosinophilia. As for asthmatic types, this was marked in the atopic type. By contrast, an increased number of neutrophils in the lavage fluid was frequently found in non-atopic or intractable asthmatics showing the frequent complication of peripheral airway disorder in pulmonary function tests. Therefore, it seems that the present study gave much information on the characteristics and the etiology of the intractable asthmatics.
3) Eosinophils in BAL fluid reflected the appearance of eosinophils in the alveolar spaces and eosinophil infiltration into the septa in the histological findings. On the other hand, neutrophils could be observed clearly by the BAL method even when they could not be observed clearly by histological studies.
In conclusion, the cytological studies performed on BAL fluid are considered useful in the diagnosis of bronchial asthma, especially for the classification into subtypes of asthma.抄録全体を表示PDF形式でダウンロード (1507K) -
第2編 気管支肺胞洗浄法による炎症性・肉芽腫性疾患の病態に関する研究竹山 博泰1981 年 93 巻 7-8 号 p. 685-700
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーCytological studies were performed on bronchoalveolar lavage (BAL) fluid in 7 cases with hypersensitivity pneumonitis, 6 with sarcoidosis, 6 with chronic bronchitis and 5 with bronchiolitis. In the cases with hypersensitivity pneumonitis and bronchiolitis, cytological studies of BAL fluid were compared with the histological findings of lungs. Furthermore, animal models of hypersensitivity pneumonitis were made and examined likewise. The results were as follows.
1) In the cases with hypersensitivity pneumonitis, a marked increase in the lymphocyte count in BAL fluid was characteristic. These cases showed an increase in the percentage of T lymphocytes in BAL fluid as compared with healthy subjects. In the cases with sarcoidosis, an increase in the number of lymphocytes was also found and especially the ratio of the percentage of T lymphocytes to that of B lymphocytes was much higher than those of the other diseases and healthy subjects.
2) An increased number of neutrophils in BAL fluid was observed in the cases with chronic bronchitis. In the cases with bronchiolitis, a marked increase in the neutrophil count was characteristic.
3) A common histological finding in hypersensitivity pneumonitis was mononuclear cell infiltration into alveolar septa and most of the cells in BAL fluid were lymphocytes. In bronchiolitis, mononuclear cell infiltration into and around the bronchiolar walls was found commonly and neutrophils were found increased in BAL fluid.
4) In experimental hypersensitivity pneumonitis, mononuclear cell infiltration into septa closely paralleled the lymphocyte appearance in BAL fluid.抄録全体を表示PDF形式でダウンロード (914K) -
森野 靖雄, 竹田 芳弘, 森本 節夫, 三宅 正淑, 林 英博, 江添 弘, 木本 真, 上者 郁夫, 橋本 啓二, 青野 要, 林 恭一 ...1981 年 93 巻 7-8 号 p. 701-708
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーMultiple polypoid filling defects of the duodenal bulb are infrequently encountered. Two cases of multiple filling defects of the duodenal bulb are reported in this paper.
Case 1. A 42 year old female complained of abdominal fullness and epigastralgia. On examination, generalized peripheral lymphadenopathy and marked hepatosplenomegaly were noted. Cervical lymphnode biopsy revealed a diffuse, poorly-differanciated lymphocytic lymphoma. X-ray examination of the gastrointestinal tract showed multiple filling defects localized at the duodenal bulb. Endoscopy disclosed multiple well-defined protrusions with small mucosal ulceration over the the whole circumference of the duodenal wall.
Case 2. A 36 year old female had no subjective symptoms. At gastric mass screening, numerous polypoid elevations of the duodenal bulb were pointed out. Detailed gastrointestinal x-ray examination showed numerous, tiny, round polypoid nodules localized at the duodenal bulb. These nodules were 2-3 mm in size with no mucosal ulceration. The endoscopic biopsy specimen revealed lymphoid hyperplasia of the duodenal bulb.抄録全体を表示PDF形式でダウンロード (1812K) -
大重 宗比古1981 年 93 巻 7-8 号 p. 709-715
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリー1. Autoradiographic study of syncytium formation between rat XC cells and MuLV-producing cells indicated that the syncytium consisted of XC cells exclusively. Virusproducing cells did not coexist with XC cells in the syncytium.
2. Human cells which formed a syncytium in response to SSAV or BaEV were transformed cells and were not normal cells. SSAV induced over a narrower range of human transformed cells than BaEV. In nonhuman cultured cells, BaEV did not induce a syncytium at all as far as tested. On the other hand, SSAV induced a syncytium in XC, GMK and CV-I cells. Anti-SSAV serum specifically blocked syncytium formation by SSAV but not by BaEV. Similarly anti-BaEV serum specifically blocked syncytium formation by BaEV but not by SSAV. Therefore, syncytium formation is specific for each virus and there is no cross-neutralization between SSAV and BaEV.抄録全体を表示PDF形式でダウンロード (1618K) -
吉田 英紀, 斉藤 大治, 兵頭 多津男, 西原 正信, 内田 俊明, 木村 正司, 武田 光, 藤井 章伸, 長花 晴樹, 原岡 昭一1981 年 93 巻 7-8 号 p. 717-727
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーElectrocardiograms (ECG) and laboratory data were studied in 130 neurosurgical patients before and after neurosurgery. The following results were obtained:
1. The postoperative ECG showed ST-T changes in 21 % of the cases with subarachnoid hemorrhage, 15 % with cerebral tumor, 37.5 % with supracellar tumor and 50 % with Parkinson syndrome.
2. In 50 % of subarachnoid hemorrhage and 47 % of cerebral tumor, postoperative ECG deteriorated within 1 week. After 2 weeks such deterioration was observed in only 37 % in the former cases and 43 % in the latter.
3. Postoperative ECGs were improved or unchanged in 83 % cases of cerebral bleeding, 75 % (within 1 week) and 83 % (after 2 weeks) of intracerebral bleeding, and in all of Parkinson syndrome. However, in the cases of supra-cellar tumor, postoperative ECGs deteriorated 100 % within 1 week and 75 % after 2 weeks.
4. Serum K+ and Ca++ were decreased significantly in the group with deteriorated postoperative ECGs. The R. B. C., Hb and Ht were decreased regardless of postoperative ECGs.
5. Postoperative ECGs deteriorated when the operation time lasted longer than 6 h or blood loss during the operation was over 1, 000 ml.抄録全体を表示PDF形式でダウンロード (1951K) -
高橋 茂, 堀井 茂男, 藤本 明, 洲脇 寛, 西井 保行1981 年 93 巻 7-8 号 p. 729-738
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーA survey of Danshukai (Alcohol Abstinence Society) members was conducted in Okayama Prefecture, November, 1978. It was based on selfcompletion quetionaires given to members attending the meetings of Okayama and Tsuyama Danshukai. Out of 290 resistered members, 202 attendants gave answers to the quetionaires (response rate: 69.7%). All of the respondents were male alcoholics. Among them, 80.6% were married, 81.2% had jobs, and 82.7% were accompanied by their wives or other family members in the meetings. This favorable family situation was in sharp contrast to that of long-term inpatient alcoholics. Admission to the Department of Psychiatry had been experienced by 63.9% of attendants and 17.3% to the Department of Internal Medicine. Many of the patients had been introduced to Danshukai by hospital staff and the activities of Danshukai were largely supported by psychiatric hospitals. In future, however, Danshukai must be more independent, establishing good relationships with community health centers or other local agencies. This means the development from a hospital-based Danshukai to a community-based one. This survey also suggested that intervention at an early stage of alcoholism is needed when alcohol-related impairment is limited to occasional violence at home. At this satage, spouses and Danshukai members might have important therapeutic roles. Regular attendance at Danshukai meetings at least once a week or twice a month seemed indispensable for continued abstinence.抄録全体を表示PDF形式でダウンロード (371K) -
第1編 In vitroにおけるヒト造血腫瘍細胞株の増殖に及ぼすインターフェロンの効果頼 敏裕1981 年 93 巻 7-8 号 p. 739-748
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーA total of 12 hematopoietic cell lines was tested for in vitro sensitivity to interferon (IF). The cell lines were 4 T-cell ALL lines (TALL-1, MOLT-4, HPB-ALL, HSB-2), 1 ATL line (MT-1), 2 null-cell ALL lines (NALL-1, KOPN-8), 1 pre-B-cell ALL line (NALM-18), 1 B-cell line (BALL-1), 1 myeloma line (Oda), 1 Burkitt lymphoma line (JBL-3) and 1 APL line (HL-60). At a concentration of 1, 000 U/ml, all 4 T-cell ALL lines, NALM-18, NALL-1 and Oda showed high or moderate sensitivity to the growth inhibition effect of IF. BALL-1 showed slight sensitvity and its in vitro growth was considerably inhibited at a higher concentration of IF (5, 000 U/ml). However, MT-1, JBL-3, KOPN-8 and HL-60 were resistant to IF and their in vitro growth was not inhibited at all even at the concentration of 1, 000 U/ml. MT-1 cells, although resistant to IF in suspension culture, were sensitive in agar culture. Colony formation was markedly inhibited at a concentration of 1, 000 U/ml. The mechanism of growth inhibition by IF and the implications of the present findings are discussed.抄録全体を表示PDF形式でダウンロード (1007K) -
園部 宏, 益田 勤, 平松 博子1981 年 93 巻 7-8 号 p. 749-753
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーTuberculoid leprosy in a 69 year-old and a 72 year-old man is presented, because the disease seems rare recently. From the experience of these cases, the importance of attention to the disease, in the everyday medical examination even today was emphasized.抄録全体を表示PDF形式でダウンロード (1127K) -
藤本 泰道1981 年 93 巻 7-8 号 p. 755-834
発行日: 1981/08/30
公開日: 2009/05/26
ジャーナル フリーヒトの翼口蓋神経節とその枝および神経節内の有髄神経束網の構造を,岐阜歯科大学解剖学第一講座所蔵の日本人成人頭部標本32例64側について,微解剖,血管注入法(レジン,朱,墨汁),顕微再構築法によって追求した.そのほかに骨部との関係をインド人頭蓋骨17例34側について調べた.その所見と考察は次のように要約される.
1) 翼口蓋神経節は,翼口蓋窩の後上部で翼突管前口(翼口蓋神経節小窩)の直前に密接して位置する.局所解剖学的指標をいくつか述べた.
2) 翼口蓋窩には.その後壁に内側稜と外側稜とがあり,翼突管前口をはさんで上下に縦走する.
3) 翼口蓋窩付近の靱帯には,翼口蓋靱帯(仮称),前翼突靱帯,ヒルトル靱帯,チビニーニ靱帯があり,第1鰓弓を誘導したメッケル軟骨の遺残であると考えられる.翼口蓋靱帯は翼口蓋窩の上内側部にあり,神経節の内側下部を横切っている. vomerovaginal canalとpalato-vaginal canalとにかけて起り,前上方へ走り上顎結節最上部後面(=下眼窩裂最内側部)につくもので,翼口蓋神経節の補強となると考えられる.
4) 神経節の枝を,立体的模型図で示した.外側への枝がほとんどないことが注目される.
5) 翼口蓋神経は,上顎神経の内側下縁から1～5本(通常3本)で出て,内側下方へ走りすぐに神経節に入る.神経節の前方を通過して直接口蓋神経に移行することがある.眼窩枝を出したり,これと吻合する場合がある.
6) 大錐体神経は,膝神経節から出て大錐体神経溝上を走り破裂孔に至る.そこで耳管上前枝が出て破裂孔前面を下行し,耳管軟骨中央部から内側1/3にかけて分布する.
7) 深錐体神経は,内頸動脈神経叢の外側枝lateral branchから起り, 1.25～5.32 mmの長さで非常に短い.
8) 翼突管神経は,大錐体・深錐体神経が破裂孔軟骨内で内頸動脈の外側で合してできる.同名動脈を伴い蝶形骨洞の直下を走り骨枝,洞粘膜枝,咽頭枝(後述)を出す.耳管上前枝が出て前述のものと吻合する.耳管上後枝が出て後走し破裂孔に入り,頸動脈管内口の上外側縁から骨中に入り耳管軟骨中央部に分布するが,これはN. sphenoidalis internusの未発達のものと考えられる.
9) 蝶形骨洞は,その下外側部には上顎神経,下壁中央部には翼突管神経による隆起があり,両神経からの洞粘膜枝が分布する.
10) 眼窩枝は,神経節の上部の発達した円錐起始部から6～17本(平均9.3本)で束状をなして起り,前束と後束とに分かれる.ともに上顎神経の内側を上行し,眼窩内と眼窩後部に至る.翼口蓋窩内で神経節の多くの枝に吻合する.
前束は,分布域が主に壁である.下眼窩裂下縁に向って前上方へ走り翼口蓋窩の上・前部の骨膜,翼口蓋靱帯の前部,下眼窩裂を閉じる結合組織や眼窩筋やその付近の眼窩骨膜に分布する.一枝は後篩骨孔を通って後篩骨洞に分布する.
後束は,眼窩後部へ行くもので分布域はおもに神経である.上後方へ走り総腱輪へ向い下眼静脈と交叉し眼窩後神経叢をつくる.そして総腱輪下部で外転神経や眼神経と吻合し,下直筋と視神経鞘に分布する.
11) 口蓋神経は,神経節下端から起り下行して大・小両口蓋神経に分岐する.咽頭枝や後上歯槽枝との吻合枝,外側下後鼻枝(後述)を出す.
12) 後鼻神経は,神経節の内側面下部から2～6本で起り,内側上後鼻枝(ms),外側上後鼻枝(ls),外側下後鼻枝(li)に分かれる.蝶口蓋孔に対しmsはその上縁を, lsは前上縁を, liは後下縁を通る. lsは上鼻甲介枝に, liは中・下鼻甲介枝になる.大口蓋神経からのliは大口蓋管の後外側壁の孔から鼻腔へ出て神経節からのliの補助となる.
13) 鼻口蓋神経は,神経節の内側面中央部から起り翼口蓋靱帯の上を越え蝶口蓋孔の後上縁に接して鼻腔に入る.同名動脈を伴い後鼻孔上縁(=蝶形骨体下面)をつたって鼻中隔に達し,鼻中隔を前下方に走り切歯管に入る.まれに(1.7%)鼻中隔のほぼ全長にわたるワナ形成がみられる.本神経と後鼻神経がとる垂れ下がった経過について発生学考察を加えた.
14) 蝶口蓋孔と上顎骨胞Bulla maxillaris前者は前後の孔内突起により8の字形をしており, 12, 13) 以外に鼻口蓋動・静脈が上縁を,外側後鼻動・静脈が下縁を通る.後者は上顎洞内面の最後部の部分的突出で,顎動脈翼口蓋窩部の彎曲部の突出によることがある.
15) 咽頭枝は,神経節の内側面下部または翼突管神経から起り咽頭に分布する神経で,翼口蓋靱帯中に入りpalatovaginal branch (pv枝)とvomerovaginal branch (vv枝)とに分岐する. pv枝とvv枝が神経節から独立起始する型と共通幹(=咽頭枝)をなす型とがある.
pv枝は,内側枝と外側枝とに分かれ,間に同名動脈をはさんで同名管内を後走し,咽頭に出て咽頭円蓋枝と耳管咽頭口枝とになる.
vv枝は,内側枝と外側枝とに分かれ,間に同名動脈をはさんで同名管内を後走する.外側枝は内側枝と吻合しおわる.内側枝はvv管下壁をつらぬきliと吻合し,またはまれに耳管咽頭口枝をなす.抄録全体を表示PDF形式でダウンロード (9218K)
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