The severity of bacillary dysentery is recognized by two factors; one is the severity of initial symptoms, the other is the duration of the illness.
On the other hand, the clinical effect of antibiotics is evaluated by the degree of alleviation of symptoms and shortening of the clinical illness.
Because an objective methodology by which symptoms are evaluated has not yet been established, the clinical evaluation of antibiotics is difficult.
Therefore, an attempt was made to evaluate the severity of cross-sectional symptoms by assigning a numerical value to each of the symptoms. The results are presented in this paper.
At first, all symptoms were categorized into three groups: fever, frequency of diarrhea and pathological products of feces. And next, relative importance of these three factors in the overall clinical severity was calculated at 16.5%, 33.3% and 50.2%, respectively.
Furthermore, the subcategories of each of these three symptom complexes was scored and ranked for its crosssectional severity.
On the basis of the table of scores obtained in such a way, the score of initial symptom of each case was obtained. From this distribution the severity was classified into severe, moderate, mild, and near normal.
Using this method, the severity of initial symptoms of Flexner dysentery in the 1930's and 1970's were compared. The result is that in male infants bacillary dysentery became significantly less serious, suggesting that the nation of lower pathogenicity or severity should be limited to male infants. In fact, the finding may be due to increased host resistance.
The other factor suggesting reduced pathogenicity of the disease may be the transmission of the epidemic strain of bacilli. For this purpose, the severity of initial symptoms between Flexner and Sonne in present day was compared. In this case, no deviation was detected in age or sex, and generally Sonne is significantly less serious than Flexner, suggesting that there is a factor in the parasite.
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