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Volume 11 (1961)
- Issue 6 Pages 383-
- Issue 5 Pages 309-
- Issue 4 Pages 236-
- Issue 3 Pages 154-
- Issue 2 Pages 80-
- Issue 1 Pages 1-
Volume 11, Issue 6
Displaying 1-10 of 10 articles from this issue
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[in Japanese]1961 Volume 11 Issue 6 Pages 383-396
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSDownload PDF (2304K) -
T. Okonogi, S. Hoshi, M. Homma, K. Suto1961 Volume 11 Issue 6 Pages 397-401
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSVitamin B1 preparation (Metabolin, Alinamin) has a strong neutralizing effect against Habusnake venom in vitro.
When Habu-snake venom is intramuscularly injected into mice or guineapigs, an acute local myonecrosis with a severe hemorrhage is recognized. However, when the venom and neutralizing quantity of Vitamin B1 are incubated in vitro, an intramuscular injection of that venom causes no local pathological change in the animals.
Subsidiary therapeutic effects of Vitamin B1 on the clinical treatment of local wounds are expected, if the preparation is used together with the antivenin treatment.View full abstractDownload PDF (3050K) -
Toyoaki Yoshino1961 Volume 11 Issue 6 Pages 402-410
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSThe gastric secretion after administration of cinchophen was studied in dogs with Heidenhain gastric pouch. An intravenous injection of cinchophen 150mg/kg to normal dogs produced a marked increase especially in the gastric pepsin concentration after 3 hours, attaining a maximal level at 6 hours, but a slight increase in the volume and the acid concentration of gastric juice which reached a peak within 3 hours. This gastric secretory response to cinchophen was completely inhibited by hypophysectomy. Even though the gastric secretory response to ACTH was closely similar to that of cinchophen, this response occurred in the normal as well as hypophysectomized dog.
The results of experiments support the hypothesis that the gastric secretion in response to cinchophen is activated through a neurohumoral mechanism via the hypothalamic-pituitary-adrenocortical system.View full abstractDownload PDF (799K) -
8. INFLUENCE OF ADRENAL EN UCLEATION ON BLOOD PRESSUREIN RATSHaruyoshi Ogawa, Isamu Sunaga, Sakutaro Tadokoro1961 Volume 11 Issue 6 Pages 411-415
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSAdult rats were subjected to this experiments. Left adrenalectomy was followed by enucleation of the right gland (AE) under the ether anesthesia. Blood pressure of tail artery was measured by conservative method. The influence of bilateral adrenalectomy was also investigated for comparison.
Blood pressure fell up to the 4th day after AE and then was recovered gradually, while after bilateral adrenalectomy it lowered without recovary losing vitality.
On the ground of the results of the present experiment, the so-colled zonal theory of adrenal cortex was discussed.View full abstractDownload PDF (737K) -
1) PRELIMINARY REPORT ON IMMUNITY ACQUIRED BYINFECTION WITH LARAEMegumi Kono, Toshisada Sawada1961 Volume 11 Issue 6 Pages 416-422
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSStudies were carried out using mice as experimental hosts to detemine whether immunity can be established against Ancylostoma caninum, and the following results were obtained;
1) The mortality of the mice, infected with the larvae of A. caninum, depended upon the numbers of larvae.
2) Mice infected with 300, 700, and 1, 500 larvae orally at the intervals of 6 days and 15 days showed a resistance to challenging infection of 5, 000 larvae orally.
3) In mice, immunized with previous infection and remarked no protection to challenging infection, less numbers of larvae were detected from organs of the body than from those of non-immunized control.View full abstractDownload PDF (930K) -
2) ON SUSCEPTIBILITY OF MICE AGAINST LARVAE ANDINFECTIVITY OF LARVAE TO MICEToshisada Sawada, Megumi Kono1961 Volume 11 Issue 6 Pages 422-431
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSThe susceptibility of ddN strain mice against Hookworm was studied by observing the change of the body weight and the mortality of mice infected with larvae of Ancylostoma caninum orally and the following results were obtained :
1) Reduction of the body weight of mice were observed as a results of infection of larvae in a few days, and the young mice showed a higher mortality than the old.
2) Lethal doses of 50 per cent to mice varied according to the age of the mouse as follows : they were in 3 weeks old mice, about 1, 200 larvae in 5 weeks old mice, about 1, 600 larvae and in 8 weeks old mice about 3, 200 larvee. The recovering of the body weight of survived mice was rapid in young mice.
3) The remarkable reduction of the infection rate of larvae was not found by the preservation of larvee for 4 to 5 weeks at 28°C.View full abstractDownload PDF (1125K) -
3) ON THE MIGRATION OF LARVAE IN THE BODY OFMOUSE INFECTED WITH LARVAEMegumi Kono, Toshisada Sawada1961 Volume 11 Issue 6 Pages 431-438
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSStudies on the migration of the larvae in the body of ddN strain mouse infected with Ancylostoma caninum orally were conducted, and the following results were obtained :
1) The larvae in the mouse after the oral infection migrated through small intestine, liver, lung, pharynx and then reached to muscular tissue, in where they were destroyed gradually.
2) The migration of the larvae from intestine to muscular tissue through finished within 4 to 5days ofter the infection.
3) The larvae were detected in stomach in 15 to 30 per cent, in small intestine in 5 to 10 percent, and in liver in 10 to per cent of the infected number of larvae, in the first day ofter infection.But the number of larvae detected in these organs decreased rapidly in the following day.
4) In lung, the larvae were detected in 25 per cent of the infected number of larvae in the following day ofter the infection and gradually decreased then after.View full abstractDownload PDF (1083K) -
L. EPIDEMIOLOGIC STUDY OF BLOOD PRESSURE LEVELSTatsuhiko Tsuji, Minoru Tsukada, Goro Kojima, Teruko Sakaino, Yuko Yam ...1961 Volume 11 Issue 6 Pages 439-448
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSMass Physical examinations were undertaken for adult population of a rural village in Gunma Prefecture, with special reference to hypertension. The number of subjects examined was 1 895 (males 767, females 1128), aged 30 and older. About 45 per cent of the same age group in the whole population was covered in the sutdy. The major findings obtained were following;
1) The rate of respondents was higher for females than males, The rates were varied among sub-communities according to administrative purpose.
2) Blood Pressure levels were considered significantly higher than the current national levels, at all ages and sexes. The trend is qnite similar with that of northeastern part of japan where cerebral hemorrhage has been most prevalent.
3) The incidence of hypertension in the sample population was analogous to those reported from north-eastern Part of japan.
4) Morbidity and disability rates were relatively high for females, particularly in aged 60 and older group. The fact might suggest that peculiar physical and social environment are responsible in inducing ill-health for the given segment of the population.
5) Anthropologic measurements revealed that they were rather slender (lighter weight compared with hgiht) but classified as broader, judging from circumference of chest.View full abstractDownload PDF (1258K) -
II Reaction of immunized mice when in jected intracutaneously with Salmonella enteritidisTadae Honda1961 Volume 11 Issue 6 Pages 472-477
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSWhen super-immunized mice with living vaccine were challenged with 104 cells of virulent strain of S.enteritidis via intracutaneous route, the bacteria increased rapidly for 24 hours, then decreased slowly in the skin, finally they disappeared. The bacteria were isolated also from local lymph nodes, but scarcely from the liver.
In the case of a small challenge dose (102 cells), the bacteria survived in the skin but were not found in the local lymph nodes, blood and liver.
The other mice were immunized with killed vaccine intra-cutaneously. when the challenge site of the skin differed from the immunized area, the challenged bacteria increased in she skin during the first 24 hours. The degree of initial increase of bacteria was similar to that in the case of the normal mice or super-immunized mice.
When the bacteria were injected at the same point of the immunized skin, however, the bacteria decreased for the first 6 hours in the skin and then increased rapidly for a few days. In the later stadium, the difference of injected site had no different effect on the concentration of bacteria in the skin.
It was considered that this decrease in bacterial number related not only to the antibody titer in the serum but also to the localized proliferation of hysteocytes after the vaccination.View full abstractDownload PDF (686K) -
1961 Volume 11 Issue 6 Pages 478-490
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSDownload PDF (2056K)
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