1. Preparation of O(H) -decomposing enzyme (Fr. 14-18) from Bac. fulminans, abolishes the O(H) - specific activity of human erythrocytes, stroma, and glycolipids belonging to the blood group OLe (a-b+), and of human erythrocytes of blood group OLe(a+b-), liberating from them only fucose as a monosaccharide.
2. Preparation of O(H) -decomposing enzyme from Bac. cereus, abolishes the O(H) -specific activity of human erythrocyes, stroma and glycolipids belonging to the blood group OLe(a-b+), and of human erythrocytes of blood group OLe(a+b-), liberating from them fucose and galactose as monosaccharides.
Furthermore, Le^b-specific activity of the blood group OLe(a-b+) erythrocytes was abolished by the action of this enzyme.
3. O(H) -combining sites on an erythrocyte of blood group OLe(a-b+) are estimated to 8.5×10⁶, and those on an erythrocyte of blood group OLe(a+b-) 77.5 ×10⁶.

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Hospital acquired infections caused by multiply resistant staphylococci present a big problem that has become increasingly serious. And staphylococcal strains type 80/81 are now widely distributed, and there are also strains which show the typing patterns 52/52A/80 or 52/52A/80/81. These strains which show the typing patterns 81, 80/81, 52/52A/80/81 and nontypable are multiply resistant.
By the lysate obtained from multiply resistant St. aureus resistant to tetracycline(TC), streptomycin(SM), sulfanilamide(SA) and penicillin(PC), resistance to tetracycline was transduced in the frequency of 10^-5. There are two types of transductant; TC resistant and lysogenized, anb also TC resistant and not lysogenized with transducing phage. The former is also able to produce phage lysate which transduce TC resistance in high frequency, but the later does not. The phage which is able to transduce TC resistance was obtained in ca. 5 per cent from multiply resistant St. aureus strains of human origin. This fact is accounted for the distribution of TC resistance in high frequency in multiply resistant patterns of staphylococci.

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Iodinated protein (s) in rat thyroid gland was extracted with an alkalized saline, and hydrolyzed enzymatically with pronase.
From time course studies of the enzyem reaction, this enzymatic hydrolysis was almost completed as short as one honr at 37°C. Enzymatically freed amino acids were then isolated on anionexchange resine, Dowex I acetate form, by use of aqueous acetic acids as eluents. Iodinated compounds in each eluate from the column were identified with known carrier compounds by paperchromatography.
From the results obtained here, the main iodinated compounds in the hydrolysate was found to be thyroxine, triiodothyronine, diiodotyrosine, monoiodotyrosine. There was no monoiodo and diiodohystidines, if any, in thyroid gland from normal rats.

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Experimental induction of gliogenous tumors was made in a total of 135 mice of C3H and C57Black strain by intra-cerebral and -cerebellar inoculation of pellets of methylcholanthrene. Fourty-nine animals were found with tumor development in a period of 135 to 528 days.
By histological examinations, the tumors were found to consist of 21 gliomas, 8 mixed glioma and and sarcomas, 18 sarcomas, and 2 unclassified tumors. Histological appearance of experimental gliomas was, in general, characterized by cytological malignancy and their mixed cellular composition. Based upon the grade of anaplasia, and the shape and growth pattern pf the predominant tumor cells, a subclassification was made. They were composed of 10 glioblastomas, 3 oligodendroglioma-like, 3 astrocytoma-like and 2 ependymoma-like tumors. The majority of gliomas, however, includes mixed or transitional features between one histological type and another.
Nineteen tumors had developed in the cerebellum. There was no tumor incidence with the histology and the ultrastructure suggestive of those of medulloblastoma in man.
Because of the histological malignancy and the frequency of mixed gliomas, no significant data was obtained as to the topographical peculiarities in different histological types of experimental gliomas.
Twenty-eight tumors including 14 gliomas, were successfully transplanted. They were capable of subsequent transfer into the subcutis and the brain of the mice of the same strain through a number of generations. By repeated transfer, the transplant came to contain uniform cells with more undifferentiated appearance. In addition, the tumors with mixed cellular composition came to separate into their original component parts.
From those observations, it is confirmed that experimental mouse gliomas have peculiarities in their cytological and biological malignancy, mixed cellular composition and their frequency of concomitant neoplastic proliferation of mesenchymal tissue elements.

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Patients with acute and chronic eczema, Lichen simplex chronicus, psoriasis vulgaris and palmo-plantal pustulosis were treated with occlusive dreesing method with plastic films (ex. Saran Wrap) and steroid ointment (in emulsion). All treated cases were exceedingly improved. In this way we recognized that the use of occlusive dressing method increased the therapeutic effectiveness of steroid ointment. In this therapy, Flucortcream (0.025 % fluocinolone acetonide cream) appeared to be more beneficial than the other steroid ointments (0.05 % dexamethasone ointment and 0.25 % hydrocortisone ointment) when used for psoriasis, but for the eczematous cases the effectiveness of all steroid ointments were roughly equivalent. In the cases of psoriasis the relapse was controled with Goeckerman therapy after cessation of the occlusive dressing method. In the eczematous cases retreatment with the occlusive dressing therapy resulted in absolute healing.
In a few cases we have seen the undesinable effects such as folliculitis, contact dermatitis-like eruptions and adhesive tape dermatitis. The contact dermatitis-like eruptions, which are caused by application of plastic films, are eythema, papules, vesicules and urticoeythema. This urticoerythematous eruption needed about 1 month for healing.

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