1) It is discussed how the centralized radiological department shoud serve the purpose.
2) For the simplification of diagnostic works in radiological department, punched cards in eluding acceptance cards, irradiation records or diagnosis ledgers are used.
3) Results obtained from the classification of the punched cards for x-ray diagnosis of digestive organs are as follows :
In 1149 radiological examinations of the esophagus, 26 cases were found to have abnormalities, including 13 cases of carcinoma : in 1124 examinations of the stomach and duodenum, 393 cases showed abnormalities, including 61 cases of carcinoma and 215 cases of ulcer; in 109 examinations of the small intestine, 18 cases showed abnormalities ; in 171 examinationes of the large intestine, 44 cases showed abnormalities ; and in 240 cholechystographies, 58 cases showed abnormalities.
out of these cases of abnormalities, 84 were operated, and it was found consequently that for 76 the diagnosis was correct and for 8 in correct.

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Although a number of clinical studies suggested that Shichijo's reaction is useful for the diagnosis of cancer of the stomach and other intestinal organs, the usefulness of this method has not been throughly evaluated in a large number of patients with cancer of intestinal tract. In the present experiment, diagnosis of cancer is made by combination of several laboratory methods (x-ray examination and histological study of the operated materials) and Shichijo's reaction has been performed repeatedly in these patients.
1) Two hundred and one patients have cancer in the gastrointestinal tract and 157 patients of those showed positive Shichijo's reaction (78.1%). On the other hand, 108 of 2823 patients who have gastrointestinal tract diseases other than cancer did show positive Shichijo's reaction (3.8%).
2) Eighty three of 201 patients have further received operation and clinical diagnosis was ascertained in all cases by histological examinations. Sixty eight of 83 cases showed positive Shichijo's reaction before operation (81.1%).
3) In order to check whether or not other factors such as size of the palpable tumor, fecal occult blood and gastric acidity are responsible for the positive Shichijo's reaction, analysis was performed in all patients, but none of those factors were closely related to positive reaction.
4) There was a slight correlation between the positive Shichijo's reaction and changes of plasma proteins.
5) Shichijo's reaction was positive even in an early stage of stomach cancer.
6) In some patients with stomach cancer, the test did not initially show positive reaction, but repeated tests showed positive reaction within one month in most of the patients (77.8%). Because of some unknown reasons, positive reaction was initially found in some patients without cancer. This false-positive reaction could be corrected by repeated examinations in most of the patients (78.8%).
7) By combined application of Shichijo's and Matsubara's reaction, clinical diagnosis of cancer became more reliable.

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Shichijo's reaction has been performed in 541 patients who have been diagnosed as having liver. gallbladder, gallduct and pancreas diseases.
1) Shichijo's reaction was positive in 80.3% of patients who have cancer of the liver, gallbladder, gallduct and pancreas, while this reaction was positive only in 7.0% of patients who have not cancer in those organs.
2) Shichijo's reaction was positive regardless of the variations of clinical manifestations, since positive reaction was observed in patients with cancer who have not anemia, palpable tumor, abnormal red blood cell sedimentation rate or derangement of liver function.
3) Only one factor which seemed related with positive reaction was the change of plasma proteins : the decrease of plasma proteins was often related with the positive Shichijo's reaction.

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The clinical usefulness of Shichijo's reaction for the diagnosis of lung cancer has been assessed in patients with several diseases of the lung. Shichijo's reaction was highly positive in patients having luug cancer who were diagnosed either by clinical findings or by postmortem examination. In contrast, positive reaction has been found scarcely in patients who have several lung diseases other than cancer. The analysis of several clinical and laboratory findings have indicated that the reaction is not strictly governed by the area of lung cancer, red blood cell sedimentation rate, concentration of plasma proteins, anemia, histological character of the lung cancer and or bronchographic findings.

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The purpose of the present paper is to standardize the clinical hemoglobinometry. The auther adopted three methods of Hb determination, that is iron determination, gas-metric method and photometric method on the same sample. Critical descriptions of each methods were described in detail with its historical review. To obtain correct absolute value of Hb, the recovery of iron from Hb was estimated by our original method. Hb with Fe⁵⁹ was synthesized in vivo by injecting Fe⁵⁹ labeled plasma into anemic rabbit prepared by blood letting. The wasted Fe⁵⁹ during the chemical process of determination was estimated accurately by the method.
The auther found the complete recovery of the Hb iron if corrected by using control sample. Thus the auther could obtain the following results :
(1) The Hb value by iron method showed about 1.7% higher than that by the gas-metric method and this is statistically significant.
(2) The Hb value by the gas-metric method and photo-metric method gave the same value, though there were some discrepancies each other.
(3) The difference of the results by iron estimation and photo-metrical determination using E₅₄₀= 0.143 was 2.3%.
(4) To determine total Hb by MHbCN method, E₅₄₀ of 0.146 was established.
(5) Some correction should be necessary, if the most recently established molecular weight of Hb is applied. For this purpose, international co-operation of the research workers of this field is further needed. At the present time the auther suspended the final decision.

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