The comparative studies on effects of Parotin and PTH preparation Kakerbin were performed by using the striped calcification figure of the rabbit's insisor dentine which was formed by parathyroidectomy, the inhibition of growth rate of dentine, and the decrease in the quantity of PTH level and serum calcium as indicators.
The results were as follows :
1) After Eiken RIA-Kit was confirmed to be able to measure rabbit's serum PTH, hypo-calcification of dentine or decrease of serum PTH level and serum calcium amount with inhibition of growth rate by parathyroidectomy were recognized as in the previous reports.
2) Normal rabbits were intravenously injected with 100u/kg of Kakerbin, and little effect was observed on the striped dentine calcification figure although serum PTH level and the quantity of calcium increased transiently and the growth rate of dentine was inhibited more or less.
The effect was confirmed on the decrease in the quantity of serum PTH and calcium or on the acceleration of the dentine calcification figure after the intravenous injection of normal rabbits with 1 mg/kg of Parotin (Lot EJ25E510), while with larger dose of 3 mg/kg of Parotin, on the decrease in serum PTH level and calcium amount, and on the formation of inhibited figure in the dentine calcification figure after transient acceleration.
3) The striped hypo-calcification of dentine which was the defective symptom by parathyroidectomy and the decrease in serum PTH and calcium levels were more strongly restored by small dose of 1 mg/kg of Parotin than the intravenous injection with 100u/kg Kakerbin, but the growth rate of dentine was hardly restored. In larger dose of 3 mg/kg of Parotin serum PTH and calcium levels were restored, but striped dentine calcification figure was restored weakly and the inhibited figure was sometimes transiently included.
4) From the results as described above, the accelerative action on calcification with Parotin and PTH was essentially identical in the stage of the inhibited calcification that caused by parathyroidectomy, but as is seen in the detailed point on effects on serum calcium, some difference in degree could be considered.

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Neutralizing antibodies to herpesvirus type 1 (HSV-1) and type 2 (HSV-2) were tested with sera obtained from patients with preinvasive and invasive cervical cancer, ovarian and corpus cancer as well as healthy control women, concerning possible association between HSV-2 and the cervical cancer.
Antibody titers to each virus type were assayed simultaneously by a microtiter technique. The percentage of women having anti-HSV-2 antibody in the cervical cancer patients was significantly higher than that in patients with corpus and ovarian cancer and in control women : cervical cancer 81%, corpus and ovarian cancer 26%, and control women 20%. However, the percentage of women having anti-HSV-1 antibody in the study group was comparable to that in control group : cervical cancer 37%, corpus and ovarian cancer 39%, and control women 28%. The mean titers of neutralizing activity to HSV-2, as given by log, of the reciprocals of the final serum dilutions that exhibit the neutralizing activity, in the cervical cancer group (2.41±1.22) was also significantly higher than those in corpus and ovarian cancer group (0.87±0.89) and in control women (0.83±0.97). This difference was independently of age. It has been noticed that in some patients with cervical cancer, especially in the stage of carcinoma in situ, the neutralizing antibody titers decreased significantly after surgical resection of the cancer tissues. These evidences suggest strong association between HSV-2 infection and the establishment of the cervical cancer, though it is not clear whether the virus has some causative role in the development of the cervical cancer or not.

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To observe the fiber architectonics of the human temporomandibular joint, i. e. that of its discus interarticularis as well as of its synovial membrane, the author carried out the following three methods. 1. The joint has been sectioned in toto with tungsten knife, by the use of Reichert-Jung Heavy-duty Mikrotome type K, after embedded in histosec and followed routine procedures. 2. The small part of the joint containing joint-space lining tissues are embedded in styrene and sectioned with glass knife. 3. The synovial membrane was stripped off under binocular microscope (10-30×) after bathed in staining fluids (membrane-like film preparation). The fiber-architectures are described of the synovial membrane and the disc. The synovial membrane consists typically of synovial cells (s in the figures), lamina propria (ps) and subsynovial tissue (ts). In the central part of the disc, where the fibro-cartilage cells are observed, the fibers of ps-layer and ts-layer and of the disc unit. In the peripheral region and the transitional parts to articular cartilage (attachment-Rees, 1954) the three layers are distinguishable. In film preparation can be obtained views unexpected from the section preparation ; fig. 16 shows the medial peripheral part in section, fig. 17 shows the synovial membrane being observed from the synovial surface in film preparation. The collagen fibers, of the ps-layer, forming bundles, run in concentric circle to the central part of the disc, but the collagen fibers of the ts-layer run radially. Elastic fibers, running in concentric circle to the same part, form three-dimentional net-work.
The fiber-running directions give a hint for the movement of the joint and its disc.

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A biopsy case of basal cell adenoma of the parotid gland was reported. The tumor was spherical in shape, measured 1.1cm×0.9cm and encapsulated by a fibrous tissue. The cut surface showed a uniform yellow appearance. Histologic picture of the tumor was acinic or tubular monomorphic adenoma with secretion of PAS-positive substance. Electron microscopically tumor cell revealed 3 kinds of cells, that is, secreting cell, non-secreting cell and myoepithelial cell. The acinus was composed of one-layered secreting cells and myoepithelial cells situated at the acinic base. The tubulus was consisted of admixture of secreting cells and non-secreting cells. Myoepithelial cells were seen at the base of the tubulus. Interstitial tissue was small in amount and collagen fibers, basement membrane-like substance and myoepithelial cells were seen in it.

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