The KITAKANTO Medical Journal

[title in Japanese]

[in Japanese]

1963 Volume 13 Issue 2 Pages 75-92
Published: March 01, 1963
Released on J-STAGE: October 15, 2009

DOIhttps://doi.org/10.2974/kmj1951.13.75

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TWO AUTOPSY CASES OF SO-CALLED CYLINDROMA

Kohzi Fukai, Kashiro Aida, Kenzi Aoki

1963 Volume 13 Issue 2 Pages 93-106
Published: March 01, 1963
Released on J-STAGE: October 15, 2009

DOIhttps://doi.org/10.2974/kmj1951.13.93

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This report deals with a male patient of 31 years and a female patient of 35 years, succumbed to so-called cylindroma, both originating in the right nasal cavity with wide spread metastatic tumor formations in the whole body after extirpation.
Both two cases were histologically diagnosed as cylindroma during their lifetimes and after repeated recurrences wide spread metastases resulted.
At the section, metastases were found in case I, cerebral base, dura, hypophysis, pleura, lungs, mediastinum, thyroid gland, lymph nodes, heart, liver, kidnies, peritoneum, thoracic vertebrae, ribs, left adrenal gland and the skin of the whole boby. In case II, metastases were found in cerebral base, pleura, lungs, sternum, ribs, thoracic vertebrae, thymus, diaphragm, liver, ovaries, uterus and periaortic lymph nodes.
Histologically, biopsy speciemen or extirpation materials of the early stages showed typical honeycomb or cribriform arrangement of epithelial cells. But in the later stages or at the section, malignancy of the tumor was increased and typical crobriform structure was decreased, having tendency to fall carciaoma simplex.
It is considered that these two cases belong to the “malignant cylindroma” because of their malignancy.

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STUDIES IN HYPERTENSION, WITH SPECIAL REFERNCES TO COLD PRESSOR AND CAPILLARY RESISTANCE TESTS

Minoru Tsukada, Tatsuhiko Tsuji, Goro Kojima, Yoshi Yano, Shizumi Mats ...

1963 Volume 13 Issue 2 Pages 107-114
Published: March 01, 1963
Released on J-STAGE: October 15, 2009

DOIhttps://doi.org/10.2974/kmj1951.13.107

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In order to find a special risk group among hypertensjve snbjects borh cotd Ptessor and capillary resistance tests have heen described in normal and hypertensive subjects. The cap illaryresistance has been shown to decrease with age in males. The level of resistancdiseas in fema-les was considered to have closer associations with room temperature, allergic esand bopy-build. The cold Pressor test also revelaed similar associations with painful sensation on immensing a hand in waters at 4 degrees centigrade and habitual exposure to cold stlmuius in daily life.
Although in cole prdsser test the incidence of hypertensive subjects was lowest in normodeaotors, relative high incidence of hypertensive subjects was found in hyporeactors and lower resistance group, particularly in males. In females the capillary resistance test was considered to have lesser significance than in males, and the hyperreactor or hyporeactor had more association with the incidence of hypertensive subjects.

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HISTOLOGICAL PICTURE AND HORMONE-DEPENDENCE OF MAMMARY CANCERS INDUCED BY 20-METHYLCHOLANTHRENE

Hideaki ISHIKURA

1963 Volume 13 Issue 2 Pages 115-125
Published: March 01, 1963
Released on J-STAGE: October 15, 2009

DOIhttps://doi.org/10.2974/kmj1951.13.115

JOURNAL FREE ACCESS

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Following the administration of 20-methylcholanthrene through the gastric tube, 34 tumors developed in mammary glands in 19 of 29 female albino rats of wistar. strain
These tumors and endocrine organs of the tumor-bearing rats were stuided pathologically, and the following results were obtained.
1) Pathologically, the tumors were tabulary adenocarcinoma. In this study, three types of these tumors were found, though in each individual case their pathological features showed little variation.
a) Large duct type wihe cancer cells proliferated around many thick layers. Seen in 8 rats.
b) Small duct type with cancer cells proliferated around one or two thin layers. Seen in 7 rats.
c) Mixed type, in which the above two were mixed. Seen in 4 rats.
2) The characteristics of the large duct type were somewhat late appearance and large size with constant growth. One case of lung metastasis was observeed. Sex-chromatin count was relatively high. From these findings, this type was considered to be estrogen dependent.
3) The characteristics of the small duct type were early appearance, rapid growth and ulcer formation. Sex-chromatin count was low, which was considered to indicate progesterone-dependence.

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