The storage of cadaver organ is an important problem of transplantation. It has been thought that hypothermia protects the cadaver organ from ischemic damage due to cellular metabolic depression.
In the present study, organic mercurial diuretics was used to inhibit the cellular enzymatic activity and also to protect a dog's kidney from ischemia in keeping the animal at normal body temperature. After ischemic period had passed, dimercaprol (BAL) which is anti-mercurial agent, was given to the experimental animals.
Method :
Animals used in the present experiment were mongrel dogs. They were anesthetized with Isozol<SUR>®</SUR> injected intravenously.
Control group : Following left nephrectomy, right renal artery and vein both were clamped for 90 minutes.
Experimental group : The procedure of both nephrectomy and clamping was performed in the same manner as that mentioned above. At fifteen minutes before interval of ischemia 90 minutes was made, mercurial drug (Igrosin<SUR>®</SUR>), 3mg/kg, was injected intravenously to the animals. After removal of the clamp, the initial dose of BAL, 6mg/kg, was given to the experimental animals. Thereafter, the same dose of BAL had been continued on daily for 2 postoperative days.
Results will be shown as follow :
No. of Survival/No.of Exp.
Occlusion (Control) Group 6/21 (28%)
Occlusion Mercurial Drug and BAL Injected Group 17/31 (55%)
P<0.05
Conclusion :
Effect of mercurial diuretics on the protection of experimental ischemic damage in the dog's kidney was significant.
The mechanism which mercurial diuretics protected ischemic damage is probably due to the fact that an organic mercurial drug might inhibit cellular enzymatic activity.

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Congenital heart disease is one of the important diseases in infancy and childhood.
In our department, we have found such anomaly in 89 of 3, 950 cases by autopsy (corresponding to 2.3%) during 25 years from 1947 to 1971.
The present report has been undertaken to know the pathological characteristic concerning the following diseases, - Persistent truncus arteriosus, Total anomalous pulmonary venous drainage, Transposition of great vessels and Tricuspid atresia.

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The acid-base balance and the changes of lactate and pyruvate were studied during the prolonged (3 hours) extra-corporeal circulation in dogs and clinical cases. The extra-corporeal circulation was carried out with mild hypothermia and 30% hemodilution.
The conclusion is as follows :
1) In order to maintain the normal peripheral circulation and carbohydrate metabolism during and after the extra-corporeal circulation, it is important to correct metabolic acidosis.
2) Even if 100% oxygen was insufflated into the oxygenator for 3 hours, the metabolic acidosis was not revealed.
3) As the non electrolyte solution for priming and the prolonged perfusion have the tendency to invite metabolic alkalosis within 24 hours, serious consideration should be given to this point in the postoperative care.

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The authors carried out tests of the mental fitness for the action requiring quickness on twenty girl students of a high school (Maebashi Girl's High School, Gunma Prefecture). The test method used here was the same as in previous report. The test was performed one time a day and over 30 times for every subject. Subjects employed in the test were members of tennis, ping-pong, basketball and badminton clubs. The scores of the test were estimated in relation to their masterly ability of sports in their club and to the school records.
The results were the following.
1) The score of the test of the girl students in progress of skill was in average a little lower than that of the boy students in a high school but higher than that of the adults including male and female of young and old.
2) The core of the test of the individual student was in close relation with her school record.
3) Among the average scores of the members of the tennis, basketball, badminton and ping-pong club was found little difference.
4) With the score of the test of each subject, it was assumable quite well her mastery ability of the sports, especially tennis or ping-pong.

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In a series of 52 cases with intracranial tumors we performed brain scan using Tc-99m pertechnetate.
Positive scans were obtained in 38 out of 52 cases, so our diagnostic accuracy was about 73%. As was presented by others, also in our series brain scan was extremely accurate in the detection of meningioma, glioblastoma and metastatic tumor (about 93% accuracy).
In detecting the intracranial tumors, angiography and air study were generally said to be more efficient than brain scan, but both methods were not complete to detect the lesions. Furthermore at times brain scan showed the lesion more accurate than angiography as was presented, therefore combination of brain scan, angiography and air study should be carried out to raise the diagnostic accuracy.
The possibilities of predicting tumor pathology and of detecting reccurent tumor by use of brain scan were also discussed.

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