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Volume 34, Issue 5
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[in Japanese]1984 Volume 34 Issue 5 Pages 315-320
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSDownload PDF (658K) -
TOSHIJI SHITARA, KIKUO NAGASHIMA1984 Volume 34 Issue 5 Pages 321-324
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSA clinical analysis was made on twenty-four children with non-Hodgkin's lymphoma.
The patients ranged in age from ten months to 14 years. The male-to-female ratio was 2 : 1. The annual incidence of the patients were increasing. Seven patients had mediastinal masses and five patients presented with abdominal involvement. Four patients had Stage I, two Stage II, eleven Stage III and seven Stage IV, according to Murphy's staging system.
The long-term survival rate was only 20% before 1980. After 1980, ten patients had treatment with modified LSA2L2 protocol. The two year survival rate of these ten patients was 71.1%. Three patients are off therapy now.
These data suggest a possible advantage for combined modality of treatment.View full abstractDownload PDF (336K) -
MITSUOMI MATSUMOTO, YASUNOBU MAEHARA, MIWAKO NOZAKI, OSAMU MITOMO, TOS ...1984 Volume 34 Issue 5 Pages 325-333
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSTranscatheter arterial embolization (TAE) was performed in 20 patients from April, 1982 to February, 1984. These patients had unresectable hepatomas due to extreme tumor extension and/or advanced accompanying cirrhosis. Angiographically, solitary hypervascular mass was seen in 8 patients, solitary mass with daughter nodules in 10, and central portal vein obstruction was in 6 patients ; 3 in the portal vein trunk and 2 in the first branch of the portal vein.
Embolic material was gelatin sponge permeated with MMC 20mg and contrast material. Under fluoroscopic guidance, these embolic materials were infused into the feeding artery through the catheter which was inserted distally to the proper hepatic artery.
Eight patients out of 20 were died until March 31, 1984. Four patients out of 8 showed proximal obstruction of the portal vein by tumor thrombus. Twelve patients are alive. Three patients out of 6 more than one year after the initial TAE are alive. Two patients with recurrent or metastatic tumor after hepatectomy are also alive.View full abstractDownload PDF (3133K) -
3. COMBINED DRUGS AND RADIOTHERAPYHIDEO NIIBE, IKU TAKAHASHI, YOSHIO TAMAKI, KAZUO MIYAISHI, ATSUSHI OKA ...1984 Volume 34 Issue 5 Pages 335-341
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSEffects of cytotoxic agent, hormone, hypoxic cell sensitizer, and radiation protector combined with radiation therapy in cancer management were analysed. The results were as follows :
1) An increase in response was seen in 25% or more of tumor nodules given radiotherapy combined with misonidazole, anoxic cell sensitizer, compared with radiotherpy alone. But the drug was also found to be neurotoxic and peripheral neuropathy.
2) Evidence has been given that Amifostine may protect the mucosal damage from radiation when Amifostine prior to irradiation was administrated to patients with tumor in the head and neck or in the pelvis.
3) There were no difference between five year survival of radiotherapy alone and with chemotherapy for patients with stage I Non-Hodgkin lymphoma. Chemotherapy following radiotherapy for patients with stage II was more effective treatment method than radiotherapy alone.
4) Radiotherapy for patients with prostate cancer was performed to control only primary site.The success rates of local control were over 80%.
The near future holds extensive promise for a combination of radiation therapy, cytotoxic chemotherapy, hormone therapy, hypoxic cell sensitizer, and radiation protectors. All of these when used in the appropriate circumstances may yield significant improvements in the therapeutic ratio and in the long-tern control of tumors.View full abstractDownload PDF (979K) -
KATSUTARO SHIBAYAMA, FUMINORI NIN, YUKIO TOMARU, HIDEO KIREN1984 Volume 34 Issue 5 Pages 343-349
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSThe authors tried to measure renal function quantitatively by an external counting method using131I-Hippuran Renocardiocystogram. For this purpose, we made a system which automatically calculate and record the half decreasing time (T 1/2) of I-Hippuran concentration in blood. Then this external counting method was assessed with 655 cases of various urinary lesions.
As the result, with the patients having no urinary retention, a good correlation was found between P.S.P. (15') and T 1/2 ; (r=0.93), while the correlation was relatively low with the patients having urine retention by various lesions. This fact shows that the external counting method is more reliable than the conventional renal function tests which need urine collection.
Conclusion : This half decreasing time calculating method with external counting, which requires a patient minimum load, is not only simple to handle but also reliable to evaluate renal function.View full abstractDownload PDF (903K) -
CLINICAL SIGNIFICANCE AND RELATIONSHIP BETWEEN TPA AND HORMONE RECEPTORYUICHI IINO, KENNEI YAMAZAKI, HIROSHI ISHIKAWA, TETSUO OGAWA, HIDEO SU ...1984 Volume 34 Issue 5 Pages 351-356
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSThe serum TPA levels were determined by radioimmunoassay in 104 cases of primary breast cancer, 13 of recurrent breast cancer, 25 of benign mammary tumor, 19 of thyroid cancer, 4 of benign thyroid disease, 7 of digestive cancer and 22 normal tissues. Estrogen receptor was measured by sucrose gradient centrifugation in 47 cases of human breast cancer and progesterone receptor in 23 cases.
The positive rate of TPA in cases of mammary cancer (37.6%) was higher than in cases of benign (12.0%) and of normal tissue (13.7%).
The positive rate of TPA and TPA levels in human breast cancer tend to become higher with progression of the stage.
The TPA levels tend to go down after operation or chemotherapy but in one exceptional case, the TPA level raised after operation on account of local inflammation. In one case, the TPA level at the recurrence showed remarkably higher than that at the primary.
There was little correlation between TPA levels and hormone receptor levels in human breast cancer, but the positive rate of TPA in receptor negative cases was slightly higher than in receptor positive cases.View full abstractDownload PDF (614K) -
NAOKO SATOU, SHOICHI TOMONO, RYOJI WAKAMATU, SHUICHI MIYAWAKI, HIDEAKI ...1984 Volume 34 Issue 5 Pages 365-368
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSA 35-year-old male was admitted to the hospital because of massive pleural effusion. Aleukocytosis with marked eosinophilia was present and the pleural effusion contained numerous eosinophils. The diagnosis of paragonimiasis Miyazakii was established by immunological studies. This is the third case of this infection in Gunma prefecture.View full abstractDownload PDF (1334K) -
KIYOHISA KOBORI, AKIRA YOKOYAMA, MITSUHIRO SHITARA, HIROAKI TAKEUCHI, ...1984 Volume 34 Issue 5 Pages 369-376
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSA 71-year-old man with esophagus lined by columnar epithelium who complained heart burn was reported. Roentgenographic study showed an esophageal ulcer accompanied by sliding hiatal hernia. Endoscopy revealed an ulcer and stenosis at the level of 37cm from incisor.
In this study, esophageal biopsies were obtained from the ulcer edge, and those were studied by light and electron microscopy. Squamous epithelium and columnar epithelium were often seen in the same specimen by light microscope. The columnar epithelium with a villiform surface was composed of abundant tall columnar cells and scattered goblet cells. These tall columnar cells were called principal cells. This type of columnar epithelium was compatible with specialized columnar epithelium of Barrett esophagus.
The columnar epithelium contained three cell types by electron microscopic observation. These were principal cell, goblet cell and enterochromaffin cell. The principal cells contained many granules up to 1.2μm in diameter, and had well developed microvilli on the apical surface. Spherical bodies, approximately 35 to 50nm in diameter, were found interspersed between the microvilli. The cytoplasm of the goblet cell was packed with well formed mucous granules and resembled those described in the small intestine. The fine structure of enterochromaffin cells closely resembled that of enterochromaffin cells found in other portions of the alimentary tract.
We conclude that the epithelium of Barrett esophagus can be distinguished morphologically from other alimentary epithelia in this way.View full abstractDownload PDF (4552K) -
Little League ShoulderNOBUO TAKAYAMA, NOBUYOSHI ARISAWA, SHIGEO MOHARA1984 Volume 34 Issue 5 Pages 377-383
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSLittle league shoulder is a rare shoulder lesion which may occur at humeral proximal epiphysis in young baseball players. Pathogenesis is exactly unknown, however, has been considered overuse injury caused result of repeated throwing. Therefore, this condition had described epiphysitis, osteochondrosis, stress fracture, or traumatic separation of humeral proximal epiphysis.
This condition is usually recovered well with rest, if the patient is not forced to play too soon often symptom subside.
This report is the cases of 12 and 13 years old boys.We treated immobilization by a shoulder spica cast, for about 3 weeks, because we considered that their pathogenesis were stress fracture or traumatic separation and they might not seek medical attention.View full abstractDownload PDF (2865K) -
TAKESHI YOSHIE, TAKEO SAKURAI, TETSUO OGIWARA, TSUNAO OGIMI1984 Volume 34 Issue 5 Pages 385-390
Published: November 10, 1984
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSCalcification of intervertebral disc in children is uncommon, usually transient in nature, and at times productive of acute symptoms such as pain and limitation of motion of the affected portion of the spine. Fourteen of such cases have been reported in our country, since Mizumachi reported calcification of thoraco-lumbar intervertebral discs in a thirteen-year-old girl. In this paper, we reported two cases of cervical intervertebral disc calcification in children;
Case (1) is a seven-year-old boy who came to us complaining of nuchal pain and stiff neck.Calcification of the intervertebral disc was found roentogenographically between the fourth and fifth cervical vertebrae. The boy was soon symptom-free and the calcification disappeared four months later.
Case (2) is a eight-year-old boy, who also came to us complaining of nuchal pain, and calcification of the intervertebral disc was found between the fourth and fifth cervical vertebrae. He was symptom-free after a week, but after a long-term follow up, the calcification still remains partially and flattening of the fifth cervical vertebra is seen.View full abstractDownload PDF (2514K)
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