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Volume 23 (1973)
- Issue 6 Pages 393-
- Issue 5 Pages 327-
- Issue 4 Pages 251-
- Issue 3 Pages 167-
- Issue 2 Pages 79-
- Issue 1 Pages 1-
Volume 23, Issue 4
Displaying 1-5 of 5 articles from this issue
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[in Japanese]1973 Volume 23 Issue 4 Pages 251-287
Published: July 01, 1973
Released on J-STAGE: February 09, 2010
JOURNAL FREE ACCESSDownload PDF (12132K) -
SAKUTARO TADOKORO, YOICHIRO HIGUCHI, NAMIKO TADOKORO1973 Volume 23 Issue 4 Pages 289-295
Published: July 01, 1973
Released on J-STAGE: October 15, 2009
JOURNAL FREE ACCESSEffects of methylprednisolone sodium succinate, a water soluble corticosteroid, on conditioned behaviors in fixed ratio (FR 30) and fixed interval (FI 60sec.) schedules of food reinforcement, as well as in Sidman's and discriminated avoidance schedules were investigated in rats.
The effects on conditioned suppression (CER) which was developed by warning stimulus associated with electric shock in FR and FI schedules, were also observed after the steroid.
These conditioned responses did not exhibit marked change following the administration of the steroid (10-40 mg/kg). However, correct response rate increased with decreasing of total responses in discriminated avoidance schedule. Such phenomena became rather prominent 24 hours after the administration; thus the mechanism was probably caused by the inhibition of ACTH-release rather than by the direct central-action of the steroid.View full abstractDownload PDF (959K) -
YASUICHI IMAI1973 Volume 23 Issue 4 Pages 297-306
Published: July 01, 1973
Released on J-STAGE: October 15, 2009
JOURNAL FREE ACCESSThe cytological response to the ingestion of Salmonella enteritidis by live vaccine immunized mouse peritoneal macrophages has been studied by electron microscopy, and following results were obtained.
1. Phagocytosis by live vaccine immunized macrophages were observed more frequently than that of normal macrophages in early stage. It seemed that phagosomes of immunized macrophages were reduced and kept in tight contact with ingested bacilli, but large phagosomes containing intact bacilli were seen more frequently in normal mouse macrophages.
2. Ingested bacilli could not be observed in macrophages nor neutrophile leucocytes 12 hours after inoculation. On the same time, roundlike structures appeared and increased gradually. Bacilli appeared from roundlike structures of normal mouse macrophages 3 days after infection, but did not appear from immunized macrophage in any time.
3. Ingested bacilli began to multiplicate in the host cells, for that reason, macrophages and neutrophile leucocytes of normal mouse were destroyed 3 days after infection, on the contrary, intracellular multiplication of ingested bacilli could not be observed in any stage both macrophages and neutrophile leucocytes of immunized mouse. It seemed to be understood that neutrophile leucocytes played some role of immunological effect as well as macrophages.View full abstractDownload PDF (22258K) -
KATSUHIRO SHIBATA, NORIO KURIHARA1973 Volume 23 Issue 4 Pages 317-322
Published: July 01, 1973
Released on J-STAGE: October 15, 2009
JOURNAL FREE ACCESSHistamine release in anaphylaxis was measured spectrophotofluorometrically by immersing passively sensitized guinea-pig small intestines in Tyrode solution containing crystalline ovalbumin. The amount of histamine release was calculated as the free base and was expressed in μg, per g, of dry tissue weight. And the effect of Compound 48/80 was investigated.
1. Histamine release from sensitized small intestines by the antigen (2.5×10-5g/ml) was 0.319±0.024μg/g.
2. Small intestines were treated with Compound 48/80 in concentration of 10-3g/ml for 15 and 30 min, and then sensitized. Histamine releases from them by the antigen increased significantly in compare with those by the antigen alone ; 0.716±0.170μg/g in the former and 0.767±0.231μg/g in the latter.
3. Small intestines were treated with Compound 48/80 in concentration of 10-5g/ml for 15 min and then sensitized. Other small intestines were treated vice versa. Histamine releases from them by the antigen were 0.230±0.040 and 0.390±0.049μg/g, respectively. The value in the latter showed significant increase when compared with that in the former.
4. Histamine release from sensitized small intestines in anaphylaxis which were preteated with Compound 48/80 of various concentratins for 15 min increased along with the increase in concentration of Compound 48/80.View full abstractDownload PDF (808K) -
SHIRO MATSUYAMA, KIKUO NAGASHIMA, TAKESHI KOITABASHI, YASUSHI TSUZUKI1973 Volume 23 Issue 4 Pages 323-325
Published: July 01, 1973
Released on J-STAGE: October 15, 2009
JOURNAL FREE ACCESSA case of pneumatic rupture of the stomach in a nineteen-month-old boy was presented. The patient who was going to be operated upon the right inguinal hernia, suddenly developed marked abdominal distention during the induction of general anesthesia under G.O.F. with a mask. The distention was not benefited by passage of a nasogastric tube. X-ray in the supine position revealed massive pneumoperitoneum showing Miller's “foot ball” sign or “air dome” sign. The pneumoperitoneum was much more evident in the confirmatory upright film.
Laparotomy was performed three and a half hours after the onset of abdominal distention. At laparotomy incision of the peritoneum released a large quantity of free air, however, no apparent perforation was found in either the stomach or the small intestine, and abdominal viscera were seemed to be intact except the small hemorrhagic and emphysematous area in the lesser omentum at the junction to the stomach near cardia. The lesser omentum was detached from the stomach and a 2.5cm. linear tear was discovered along the lesser curvature. The rent was sutured in two layers and peritoneal cavity was thoroughly irrigated with warmed sterile saline. No local antibiotics was instilled and on drainage was employed. Postoperative course of the patient was uneventful.View full abstractDownload PDF (967K)
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