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Volume 42 (1992)
- Issue 6 Pages 527-
- Issue 5 Pages 425-
- Issue 4 Pages 331-
- Issue 3 Pages 165-
- Issue 2 Pages 69-
- Issue 1 Pages 1-
Volume 42, Issue 4
Displaying 1-11 of 11 articles from this issue
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YASUHIRO KAWASHIMA1992 Volume 42 Issue 4 Pages 331-343
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSIn stereotactic thalamotomy, the final placement of radiofrequency therapeutic lesion should be made by considering individual anatomical and functional differences in the thalamus. To estimate individual anatomical variations in the thalamus prior to stereotactic thalamotomy, special studies using MRI were performed.
The features of proton density MR image are similar and compatible with the myeloarchitectonic features of Schaltenbrand's atlas, which has been used widely as the standard atlas for stereotactic thalamotomy. Considering the characteristics of cyto-and myeloarchitectonic features of thalamic nuclei, an identification of each thalamic nucleus may become possible by carefully observing the MR image.
An MR image parallel to the intraoperative oblique trajectory provides practical information for determining a safe trajectory and tentative target point. On the MR image, the distance from the tentative target point to the various subcortical structures could be estimated before operation. The findings of depth electrode recordings made during surgery corresponded well with the anatomical findings depicted on MRI.
MRI is very informative in terms of evaluating the individual anatomical variations. However, as MRI does not show detailed functional localization, to obtain consistently excellent operative results, the final target should be determined on the basis of the findings obtained by elecorophysiological methods.View full abstractDownload PDF (4275K) -
HITOSHI KATAHIRA1992 Volume 42 Issue 4 Pages 345-351
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSMethionine synthetase activity is decreased in megaloblastic anemia due to vitamin B12 deficiency. The decrease in activity causes intracellular accumulation of 5-methyltetrahydrofolate and, consequently, DNA synthesis is impaired. B12 deficiency also leads to a decrease in the formation of methionine, the product of methionine synthetase. We recently observed that in vitro administration of methionine to bone marrow cells from patients with megaloblastic anemia due to vitamin B12 deficiency, significantly improved the deranged DNA synthesis that is characteristic of the disease. In order to examine whether DNA methylation is reduced in B12-deficient megaloblastic anemia, we determined the 5-methylcytosine content in total genomic DNA extracted from megaloblastic, leukemic, and control bone marrow cells by high performance liquid chromatography. There was no significant difference in the methylation of cytosine in these three groups; mean values of % mC (methylated cytosine as compared to totalcytosine) for six patients with megaloblastic anemia, five patients with leukemias, and five control subjects were 3.89, 3.88 and 3.79%, respectively. From these results, it was concluded that the methylation of cytosine residues is preserved at least in the patients with megaloblastic anemia examined here.View full abstractDownload PDF (1035K) -
KYOICHI IMAI, TAKANORI SUZUKI, MASAMICHI HAYASHI, AKIO SHIONO, YOSHIMI ...1992 Volume 42 Issue 4 Pages 353-359
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSThe significance of prostatic specific antigen (PA) was investigated in subjects examined by means of mass screening for prostate cancer (Pca) from 1985 to 1990. All subjects were examined by digital rectal examination (DRE) and prostatic acid phosphatase (PAP). Some subjects with abnormal DRE and/or elevated PAP were advised to undergo secondary screening to confirm the presence of Pca. The relationships among PA, prostate size estimated by DRE, and age were investigated in subjects whose diagnoses were normal or benign prostatic hypertrophy (BPH). Serum PA levels of subjects over 50 years of ago were higher than those of cases under 50 years. Serum PA level apparently increased with the size of the prostate. The cut off value for PA was determined from the subjects with normal sized prostates and BPH. When the cut off value was 6.5ng/ml, the sensitivity, specificity and efficiency of Pca as a marker were 80.6%, 94.6% and 76.2%, respectively. All ten Pca patients with elevated PAP and six of 21 ones with normal PAP demonstrated abnormal PA. It was concluded that PA improves the Pca detection rate in mass screening.View full abstractDownload PDF (1033K) -
A COMPARATIVE CLINICOPATHOLOGIC STUDYMITSUE KAWARAI, YOICHI NAKAZATO1992 Volume 42 Issue 4 Pages 361-368
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSA comparative histopathological study of aortitis syndrome was performed in terms of the duration of illness. Five autopsy cases were divided into two groups, three short term cases and two long term cases. The aortic lesions of the short term group were characterized by the presense of pathognomonic granulomatous inflammation. These consisted of epithelioid cell granuloma including multinucleated giant cells and dense infiltration of lymphocytes and plasma cells. There was no atherosclerotic change in the intima. On the other hand, the aortae of the long term group showed severe atherosclerotic change in the intima. Their lumens were dilated, even forming a large abdominal aneurysm in one case. Fibrosis, loss of smooth muscle cells and elastic fibers, and splitting of the inner aspect were frequently observed in the media. There was a dense fibrosis in the adventitia. It is suggested that the formation of a slit-like space in the inner half of the media represents a characteristic lesion of aortitis of longer duration. Improvement in chemotherapeutic regimens, including corticosteroid therapy, might be responsible for the favorable prognoses seen in the long term group.View full abstractDownload PDF (4028K) -
SHIYOICHI AIBA, HIDEO SHIOZAKI, HIROSHI MATUMOTO, TOSHIO IKEYA, ICHIRO ...1992 Volume 42 Issue 4 Pages 369-377
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSTorsion of the sigmoid colon is a rare disease. However, the authors have experienced 15 cases of this disease over the past 20 years. The disease is commonly found in aged people. But its characteristics remain unclear. The reason might lie in different etiologies. In order to elucidate the etiology of the disease, the 15 cases were studied by dividing them into A : younger group (under 50 years ; 6 cases) and B : aged group (over 50 years ; 9 cases). The younger group consisted of one male and five females with ages ranging from 14 to 41 years (on average : 29.5), and predominantly had congenital factors such as Hirschsprung's disease, mesenterium commune, and dementia. The six younger patients underwent 11 treatments, including one patient undergoing operative detorsion only. The aged group was comprised of six males and three females with ages ranging from 55 to 80 years (on average : 68.9). In this group, it could be infered that some acquired causes such as chronic constipation had contributed to torsional anatomical causes such as sigma elongatum mobile, leading to the torsion. Conservative treatment with endoscopic detorsion was performed in three cases. The authors experienced one case which was difficult to treat conservatively, and might be susceptible to recurrence of indefinite onset.View full abstractDownload PDF (2155K) -
CLINICAL CHARACTERISTICS, THERAPUETIC EFFECT OF PGE1 AND PROGNOSISYASUKO NAKAMURA, ISAO KOBAYASHI1992 Volume 42 Issue 4 Pages 379-385
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSThe prevalence of diabetic foot among hospitalized diabetic patients was 0.53% during the period from 1983 to 1990, and has increased to 0.95% over the last three years. The average age and duration of diabetes in nine cases were 59 years old and 7.6 years, respectively. Most of the patients had poorly controlled levels of blood glucose before admission, but four out of the nine patients showed fairly well-controlled levels and had HbA1C values below 9.0%. Half of these fairly well-controlled patients had bullous lesions on their feet suspected to be bullosis diabeticorum. Localization of the lesions was mostly on the toes, then soles and external malleolus of the feet. Staphylococcus aureus was most frequently cultured from the lesions and, recently, methicillin-resistant strains of Staphylococcus aureus have been cultured. All of the patients had complications including neuropathy, retinopathy and nephropathy. Neuropathy was the most frequent complication seen with diabetic foot. Intravenous administration of prostaglandin E1 had a potent effect in treatment of the ulcer-type of gangrene, but had no beneficial effect on the ishemic-type of gangrene in our cases. Of these cases, 77.8% were healed by PGE1 treatment. By January of 1991, four subjects had died from heart failure, cancer, or sepsis. Three out of the four had recurrent the lesions and all had died within five years of the appearance of their first lesion.View full abstractDownload PDF (971K) -
AKIHIKO SHIONO, KYOICHI IMAI, HIDETOSHI YAMANAKA, JUN KOYA, HISANORI Y ...1992 Volume 42 Issue 4 Pages 387-394
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSA clinicoepidemiological study was conducted on patients who had visited our hospitals between April, 1990 and March, 1991, and we analyzed trends among male urethritis cases in Gunma.
The total number of patients with male urethritis during this period was 317. The incidence of gonococcal urethritis (GU) was 27.8% and that of non-gonococcal urethritis (NGU) was 72.2%. In NGU, Chlamydia trachomatis was detected in 34.9%. Both GU and NGU were most commonly observed in patients in their twenties and thirties, and prostitutes were the most common source of the infection. New quinolones and minocycline were frequently administered.View full abstractDownload PDF (1025K) -
TOSHIO KONISHI, TAMIYUKI OHBAYASHI, TATSUO KANEKO, TOSIHIDE OHKI, YASU ...1992 Volume 42 Issue 4 Pages 395-399
Published: July 01, 1992
Released on J-STAGE: February 17, 2010
JOURNAL FREE ACCESSTwo cases of angina pectoris complicated by severe anemia underwent coronary artery bypass grafting. Erythropoietin was used preoperatively in these cases to improve anemia. The red blood cell count and blood hemoglobin level gradually began to increase, and autologous blood donation was performed several weeks leter. No homologous blood transfusions were needed because of the increased hemoglobin level and autologous blood deposits. No adverse effects were recognized in either case and they were discharged without complications. It was remarkable that erythropoietin was effective despite hypoplastic bone marrow in one case.
Curreutly, blood transfusions for cardiovascular surgery are becoming unnecessary because of the numerous support systems for blood conservation techniques : anemic conditions are the exception. It is assumed that erythropoietin has introduced a new era in the trertment of these surgical cases with anemic disorders, and that homologous blood transfusions will become increasingly infrequent.View full abstractDownload PDF (2357K) -
JUNJI ISHIHARA, TADAO MATSUSHIMA, JINICHI KOJIMA, KAZUO WATANABE1992 Volume 42 Issue 4 Pages 409-415
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSA series of three cases of brain tumors associated with intracerebral hemorrhage is described. These tumors may mask the cause of bleeding and make the diagnosis difficult. Most tumors causing intracerebral hemorrhage are highly malignant, suih as glioblastoma or metastatic brain tumor. The initial symptoms were stroke-like onsets, such as sudden headache, vomiting and hemiparesis. No vascular lesion was demonstrated on angiography. These cases underwent surgery immediately. Histological diagnoses were a glioblastoma, a cystic angioma and a malignant lymphoma. Brain tumors associated with intracerebral hemorrhage are discussed.View full abstractDownload PDF (4963K) -
YOSHIYUKI SAKATA, MASAMICHI KAWABE, NAOKI TOMIZAWA, SHIGEO TOTSUKA, TE ...1992 Volume 42 Issue 4 Pages 417-422
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSA 75-year old female underwent the examination of hematuria, and an abnormal calcification shadow was found in a plain abdominal roentgenogram. Splenic artery aneurysm with calcification was diagnosed by means of various imaging methods. Aneurysmectomy and splenectomy were performed. Her postoperative course was favorable. Splenic artery aneurysm shoule be suspected when an abnormal calcification shadow is found on a plain abdominal roentgenogram.View full abstractDownload PDF (2168K) -
1992 Volume 42 Issue 4 Pages 423-424
Published: July 01, 1992
Released on J-STAGE: October 21, 2009
JOURNAL FREE ACCESSDownload PDF (425K)
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