infection, which has been usually recognized as atypical pneumonia, has epidemic outbreaks at four year intervals. M. pneumoniae is also a pathogen of upper respiratory infections, such as pharyngitis and otitis media.
In 1992, 9 cases of patients, who visited my ENT office complaining of acommon cold, showed high titers of M. pneumoniae antibody. All of them were childen. Five cases had otitis media, 3 cases had pharyngolaryngitis and 1 case had tonsilitis with pneumonia. I experienced anothere pidemic outbreak of M. pneumoniae infection 11 years ago in 1980.
Atypical pneumonia (M. pneumoniae Pneumonia) has been one of a number of epidemic diseases under a national statistic survey since 1982. Cases with atypical pneumonia at reporting clinics are informed to local health centers, prefectural offices and the Welfare Ministry which publicly reports statistic data of this disease every week. According to the rlational report, atypical pneumonia had an epidemic outbreak in Isikawa Prefecture in 1992. In Isikawa Prefecture, the number of weekly reported cases per reporting clinic was more than 1.0, and much higher than the national average, Because of this outbreak, I found many patients with M. pneumoniae infection presenting ENT symptoms. Local epidemic outbreak of the disease, however, is not always accompaind with the rise of the number of the national statistic survey.
There was one case, whose pharyngeal tonsil was markedly swollen and covered with thick exudate. This finding is suspected to be due to the histologic specificity of the pharyngeal tonsil.
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