Background: Radical tumor resection is regarded as the treatment of choice for paranasal malignant tumors invading the adjacent structures. Tumors showing limited extension can be managed by less aggressive therapy.
Objective: To evaluate the usefulness of endoscopic endonasal surgery for malignant paranasal tumors by classifying the type of surgery according to the extent and site of origin of the tumor, and investigate the clinical course.
Materials and methods: Seven patients underwent endoscopic tumor resection for paranasal tumors, five patients received radiotherapy, and one patient received chemotherapy. Six of the seven patients treated by the endoscopic surgical approach were male and one patient was female, with an average age of 61 (range 45-76) years. The mean follow-up period was 41.1 (range 12-125) months.
Results: All tumors were resected with some safety margin in an en-bloc manner by the endoscopic endonasal approach. CSF leakage occurred in one patient and was repaired at the same time as the resection. One patient died of the disease at 12 months after the treatment, and one patient (neuroendocrine carcinoma) was alive with the disease at 36 months after the treatment; the remaining patients were alive without the disease. The type of surgery was classified into three types; the medial type, for tumors originating medially from the nasal septum; the superior type, for tumors originating superiorly from the medial nasal turbinate; the posterior type, for tumors originating posteriorly from the superior nasal meatus.
Conclusion: In very carefully selected cases where the tumor does not invade the adjacent structures and allows some safety margin be obtained, endoscopic endonasal tumor resection, without the need for a lateral skin incision, may be useful. Although the endoscopic approach is useful for treating sinonasal tumors, we should recognize its advantages and limitations, and choose an adequate approach considering the extent and site of origin of the tumor.
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