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Volume 36 (1993)
- Issue 6 Pages 677-
- Issue 5 Pages 545-
- Issue 4 Pages 419-
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- Issue 2 Pages 113-
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Volume 34 (1991)
- Issue 6 Pages 595-
- Issue 5 Pages 507-
- Issue 4 Pages 385-
- Issue 3 Pages 261-
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Volume 31 (1988)
- Issue 6 Pages 757-
- Issue 5 Pages 613-
- Issue 4 Pages 425-
- Issue 3 Pages 273-
- Issue 2 Pages 127-
- Issue 1 Pages 9-
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Volume 36, Issue 6
Displaying 1-17 of 17 articles from this issue
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[in Japanese]1993 Volume 36 Issue 6 Pages 677-684
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
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Yasukazu Mikami1993 Volume 36 Issue 6 Pages 685-695
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSUsing cultured cells of head and neck squamous cell carcinomas, the production of basic fibroblast growth factor (bFGF), being one of angiogenetic factors, and the effect of antibFGF neutralizing monoclonal antibody and exogenous recombinant human bFGF on cell growth were examined. Furthermore, the relationship among the bFGF level in culture supernatants of tumor cells, the micro-vessel number (angiogenesis) evaluated by F VIII RAG staining, and the histological grade of malignancy assessed by the number of argyrophilic nucleolar organizer region (AgNOR) in the identical tissue specimens to cultured tumors were investigated.
The detectable levels of bFGF in culture supernatants were observed in all of twelve tumor cells and this production of bFGF was enhanced by the addition of tumor necrosis factor-α(TNF-α) into the culture. Anti-bFGF neutralizing monoclonal antibody inhibited the cell growth in two of examined four cultured tumor cells. The addition of recombinant human bFGF into the culture, however, did not augment the growth of these cultured tumor cells.
A significant relationship between the bFGF level in culture supernatants of tumor cells and the micro-vessel numbers in identical tumor tissues was observed, but this bFGF level did not correlate with the AgNOR number.
These results indicate that bFGF is an important one of angiogenetic factors and bFGF production by tumor cells may enhance tumor growth in vivo through angiogenesis.View full abstractDownload PDF (3551K) -
Mamoru Okihisa, Tatsuya Kitamura, Masato Matsui, Takao Saitou, Hidehik ...1993 Volume 36 Issue 6 Pages 696-702
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSWe observed a patient aged 69 whose audibility in the low frequencies was deteriorated when his posture was changed from supine to sitting position. He suffered a subarachnoid hemorrhage and on the same day he received an aneurysm clipping. Subsequentry, ventriculo-peritonial shunt surgery was performed because hydrocephalus occured.
He recovered consciousness, but low cerebrospinal fluid syndrome such as headache developed postoperatively. At the same time, he noticed that his hearing became worse when he changed posture from supine to sitting position. The symptoms were improved subsequently as a result of changing the setting of cerebrospinal fluid pressure, but the patient visited our department because the hearing fluctuation persisted.
The tympanic membranes were normal and both sides of tympanograms were A type. We diagnosed cochlear hearing loss based on neurootologic examinations, and CT shows wide cochlear aqueducts on both sides. As the cause of the audibility fluctuation by posture, it was presumed that the collapse of perilymph due to overflow of cerebrospinal fluid through the V-P shunt causes a relative endolymphatic hydrops and hearing in the low frequencies is impaired.View full abstractDownload PDF (8325K) -
Shinji Nishizawa1993 Volume 36 Issue 6 Pages 703-708
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSThe purpose of this testing was to study the length of time to return to the pre-exam tympanic membrane temperature (TMT), the mode of tympanic temperatures, and applying a function which was derived from such a change, when caloric tests were performed. A total of 120 subjects with normal eardrams (240 ears) while complaining of vertigo were examined. TMTs were measured using infrared non-contact tympanic membrane thermometers at precaloric test, one minute after such a caloric test with 20 ml water. of 20°C irrigated for 20 seconds, to ten minutes with one minute intervals, to 15 and 20 minutes, respectively. Of the ascending rate of TMTs, it was the highest rate from one to two minutes at 2.2°C and that rate decreased gradually. After 15 minutes, the TMT neighbored with the pre-exam TMT, and both TMTs were not significantly different. In a first three minutes, TMTs =32.5°C +6.62 log (minutes) °C could be applied. TMT is higher by 0.4°C than that of axillary taken with an electronic predictive thermometer.View full abstractDownload PDF (4601K) -
Yasuyuki Kimura, Takeo Donjo, Toshiaki Tsukatani, Makoto Sakumoto, Tak ...1993 Volume 36 Issue 6 Pages 709-716
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSWe examined 10 patients with olfactory disorders caused by brain tumors during the period from October, 1988 to December, 1992. The results were as follows.
1. Seven of the 10 patients did not recognize olfactory disorderes, however no patients were normal. Although unilateral olfactory disorder is one of the important symptoms in intracranial diseases, unilateral olfactory test is not yet a routine test.
2. In the standard olfactory test, we regard the difference between detection threshold and recognition threshold of over 2.0 as dissociation. Five patients showed the dissociation. The dissociation might occur when the amount of information to the olfactory centers is in insufficient supply, or the third olfactory center is diseased.
3. In the intravenous olfactory test, the central olfactory disorders were characteristic in that the latent time was normal and the duration time was highly shortened.View full abstractDownload PDF (8619K) -
Kazuo Shibutani, Yasuyuki Kimura, Ikuo Nagayama, Mitsuru Furukawa1993 Volume 36 Issue 6 Pages 717-722
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSA 55-year-old man complained something unusual of the left visual field. In ophthalmology he had a nasal and lower altitudinal quadrantanopsia of his left eye field. CT and MRI showed severe maxillary sinusitis, but no lesions in the posterior ethmoid or sphenoid sinuses. The maxillary sinus was well developed and the top of the sinus was very close to the optic nerve. 47 days after Caldwell-Luc's operation, the field of vision became near normal.
When we see medial-inferior quadrant blindness, we infer a lesion in the lateral-superior part of the optic nerve, but in this case MRI and CT scan showed maxillary sinusitis only. We presume that severe maxillary sinusitis has caused the blindness.View full abstractDownload PDF (7340K) -
Tetsuya Tahara, Mayuri Okami1993 Volume 36 Issue 6 Pages 723-726
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSThe incidence of primary nasal tuberculosis is rare. We report a case of primary nasal tuberculosis in a 59-year-old female who complained of nasal obstruction in the right nasal cavity. There was a mass lesion in the nasal septum on the right side. Her chest X-ray showed no signs of lung tuberculosis. Histopathological examination of the lesion revealed findings which were compatible with tuberculosis. The lesion was cured by the use of INH and RFP.View full abstractDownload PDF (7408K) -
Hiroki Mitani, Yosuke Kamide, Yuji Umezawa1993 Volume 36 Issue 6 Pages 727-734
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSTwo cases of malignant external otitis are reported. One patient was a 81-year-old female who was affected with diabetes mellitus and complained of right earache, ear discharge and facial paralysis. The other patient was a 42-year-old female who was affected with diabetes mellitus and complained of right earache, hearing loss and facial paralysis. In the two patients pseudomonas aeruginosa was isolated from the discharge. Malignant external otitis in elderly diabetic patients was shown to be caused by pseudomonas aeruginosa. Local and systemic antibiotic therapy, debridement of necrotized tissue and strict control of the diabetis are important in the management of malignant external otitis.
MRI was useful in determining the extent of the inflammation and in evaluating the effect of treatment.View full abstractDownload PDF (16168K) -
TREATMENT OF THEFONTANELLEMasashi Ozawa, Shinichi Sano, Hirohito Horiuchi, Shin-ichi Haruna, Hir ...1993 Volume 36 Issue 6 Pages 735-740
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSThe surgical treatment of chronic sinusitis has become more conservative following the introduction of the endoscopy to this field. The probable reason for this change is that use of an endoscope allows direct and clear observation of the operative field. The present study was conducted in patients with chronic sinusitis to compare the results of two groups of patients treated by rigid endoscopy. In one group, the fontanelle including the maxillary ostium was conserved, while in the other group the fontanelle was excised as completely as possible. The preoperative severity of the sinusitis was similar for both groups. Postoperative X-ray examination of the maxillary sinus showed that the rate of improvement was higher in the excision group than in the conservatively treated group.
Furthermore, the excision group showed higher rates of improvement for symptoms such as postnasal drips and disturbance of normal daily activities. Although the fontanelle can be conserved during endoscopic endonasal sinus surgery, the findings of this study suggest that more successful results are obtained by excision of the fontanelle.View full abstractDownload PDF (749K) -
Takao Saitoh, Takakuni Katoh, Syozou Kaneko, Sirou Simada, Hiroshi Mor ...1993 Volume 36 Issue 6 Pages 741-746
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSWe studied clinical features of 16 cases, diagnosed as sphenoid sinus neoplasma by CT scan, during the seventeen years from 1975 to 1991. These patients showed nasal symtoms in 50%(8/16), diplopia by abducens nerve paralysis in 80%(13/16), blepharoptosis by oculomotor nerve paralysis in 50%(8/16), lack of optesthesia by optic nerve paralysis in 43%(7/16).
We studied the relation between cranial nerve paralysis and the tumor invasion of the sphenoid sinus, ethmoid sinus, nasal cavity, and cavernous sinus. On the other hand, of these cases, six cases (32%) showed epistaxis and 10 cases (62%) showed headache. We suggested that these symptoms are important signs for early diagnosis and differential diagnosis from benign tumor.View full abstractDownload PDF (3331K) -
Ichirou Ogiwara, Itsurou Miyajima, Yoshio Honda1993 Volume 36 Issue 6 Pages 747-754
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSA case of Cryptcoccosis with adult T-cell leukemia is reported. The case is a woman, aged 40, who visited our hospital with the complaints of bilateral neck lymphadenopathy. In the first place we suspected epipharyngeal carcinoma with metastasis to neck lymphnodes, but we found Cryptcoccos neoformans and atypical lymphcytes at the same lymphnode histologically.
We report underlying disease and the method of the treatment in Cryptococcosis.View full abstractDownload PDF (11375K) -
[in Japanese], [in Japanese]1993 Volume 36 Issue 6 Pages 755-769
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSDownload PDF (34757K) -
[in Japanese]1993 Volume 36 Issue 6 Pages 770-775
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSDownload PDF (640K) -
1993 Volume 36 Issue 6 Pages 776-796
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSDownload PDF (11539K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese]1993 Volume 36 Issue 6 Pages 797-802
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1993 Volume 36 Issue 6 Pages 803-814
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESS -
[in Japanese], [in Japanese], [in Japanese], [in Japanese]1993 Volume 36 Issue 6 Pages 815-821
Published: December 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESS
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