JIBI INKOKA TEMBO
Online ISSN : 1883-6429
Print ISSN : 0386-9687
ISSN-L : 0386-9687
Volume 56, Issue 5
Displaying 1-37 of 37 articles from this issue
ORIGINAL PAPERS
  • Kazuhisa Yamamoto, Tomokatsu Udagawa, Yuichiro Yaguchi, Nobuyoshi Otor ...
    2013Volume 56Issue 5 Pages 238-244
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     We retrospectively reviewed a series of 9 revision stapes surgeries performed for otosclerosis between January 1984 and March 2012. The clinical history, preoperative findings, intraoperative findings, causes of failure, hearing results and postoperative clinical courses were evaluated. The average interval between the previous surgeries and the revision surgeries was 5 years 9 months. During the revision surgery, we found displacement of the prosthesis in 7 ears and presence of fibrotic tissues around the prosthesis in 2 ears. Incus necrosis was observed in one case. In 7 of the 9 ears, successful hearing results (postoperative air-bone hearing gap of 10 dB or less) were obtained according to the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) guidelines. Although the hearing results of the revision surgeries were inferior to those of the primary surgeries, hearing improvement was obtained in most of the cases of revision surgery. We concluded that for revision stapes surgery, it would be better to select patients with a positive attitude. Flexibility to deal with the various intraoperative findings in each case and careful surgery are also required.
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  • Yuika Sakurai, Momoko Yamazaki, Kiyoshi Komiya, Nobuyoshi Otori, Hirom ...
    2013Volume 56Issue 5 Pages 245-252
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     The word “visualization” has been well known, and this matter should be applicable to the medical community, but this has not already been done. When considering postgraduate education in Otorhinolaryngology (ENT), there is no clear curriculum. And creating a detailed curriculum is left up to each institution. Our past report about young doctors of our department, there were differences in the learning situations among individuals. Therefore, we developed a system called “visualization of techniques” as an educational method for young doctors aimed at specialist of ENT. This system is intended for growing high quality specialist, and eliminates the gap between individuals. We classified the major surgeries by the target number of years each. And we also set a target number of cases for each surgery. In this paper, we report the learning level of surgery by young doctors before this system started. The results suggested that surgical experience of 2~3 years after employment is important time for target achievement of “five-year basic surgery”. In the future we will compare the results of before and after the start of this system. And based on these results, we will continue to improve this system for the development of high-quality ENT specialist.
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  • Ryohei Akiyoshi, Satoru Fukami, Itsuo Nakajima, Hidechi Yamakawa, Wata ...
    2013Volume 56Issue 5 Pages 253-257
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Autoimmune neutropenia (AIN) is a disorder caused by the appearance in the blood of antibodies directed against a patient's own neutrophils, causing increased peripheral destruction of neutrophils. It is a rare congenital neutropenia, and the clinical course is characterized by recurrent bacterial infections. We report a child with a neck abscess who was suspected as having underlying autoimmune neutropenia.
     A 19-month-old girl with a history of recurrent otitis media was admitted to the hospital. Examination revealed swelling of the neck in the right parotid and mandibular areas. Laboratory data showed a white blood cell count of 17,000/μl, with a differential neutrophil count, however, of only 3.0%. CT scan showed an abscess in the right upper neck. The child was successfully treated with antibiotics and frequent needle drainage of the abscess. She was also started on granulocyte colony-stimulating factor (G-CSF). Subsequently, a repeat CT scan revealed complete resolution of the abscess.
     Follow-up has not revealed any recurrence of the neck abscess until date, or indeed any other significant infection. Serological testing for neutrophil antibody did not reveal any neutrophil-reactive IgG antibodies, however, we diagnosed AIN based on the clinical manifestations.
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  • [in Japanese]
    2013Volume 56Issue 5 Pages 277
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
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  • Yohei Okayoshi, Kiyoaki Tsukahara, Kazuhiro Nakamura, Rei Motohashi, M ...
    2013Volume 56Issue 5 Pages 278-281
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     A pharyngeal foreign body is a common disease in the otolarygological outpatient setting. Usually it can be removed orally, but there are some cases with difficulty in removing the substance buried beneath pharyngeal mucous membrane. We encountered two cases of the foreign bodies buried beneath the pharyngeal mucous membrane which were successufully removed using navigation system. The case 1 is a 67-year-old woman. Its chief complaint is a throat pain after ingestion of a squid. We couldn't find out the foreign substance which was suspected in CT by using a laryngopharynx fiber and an upper gastrointestinal endoscope. The neck abscess detected on the 8th day. The metal piece-like foreign substance was suspected by CT, and the 24-mm metal wire buried beneath the posterior wall of the pharynx was removed by use of navigation under general anesthesia. The case 2 is a 63-year-old woman. Her chief complaint is a throat pain after ingestion of a barracuda. A foreign body in the oropharynx posterior wall was suspected in CT. We couldn't remove the foreign body by using navigation system. A clip was hooked in the posterior wall of the pharynx as a marking. Next day we were able to identify the position of the fishbone from the position of the CT and, successufully removed the fish bone.
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  • Shinichiro Etoh
    2013Volume 56Issue 5 Pages 281-284
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Brainlab introduces “CURVE” as new navigation platform in autumn 2012. It was developed under the product concepts; “Sophisticated ergonomic design”, “Integrated multi-purpose interface”, “Digital HD technology”. CURVE is versatile navigation platform including compatibility with DICOM images and other intraoperative optical instruments in order to enhance functionality in OP room. This is the first introduction to unveil its new features in Japan.
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    2013Volume 56Issue 5 Pages 285
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese]
    2013Volume 56Issue 5 Pages 285-1-285
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
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  • Kimberly Hill, Minami Sugimura
    2013Volume 56Issue 5 Pages 286-288
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Medtronic has developed and sold various products specialized for ENT surgeries for many years. This time we describe our new product, Fusion® ENT navigation system, releasing on December 2012.
     We have already introduced hybrid optical-electromagnetic navigation system called “Stealth Station S7®”. Fusion system employs only electromagnetic navigation system dedicated for ENT department and is very simple to use.
     The electromagnetic navigation system generates a low-energy magnetic field and tracks the location of the patient and instruments with dedicated trackers. Because of this mechanism, Fusion system makes it possible to control instruments more freely compare to optical navigation system. Furthermore the tracker is smaller and lighter so that surgeons and the patients feel less stress during the surgery.
     Fusion system attracts increasing attention and has already been installed over 1,000 in the world.
     We will keep developing less invasive and more user-and patient-friendly products for the future.
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  • ―AS THE INDEX OF NAVIGATION SYSTEM SELECTION―
    Kazuyasu Baba, Mikiya Asako, Hideyuki Murata, Koichi Tomoda
    2013Volume 56Issue 5 Pages 288-291
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Now, the navigation system is used in about 80% of university hospital. We have the use experience of several kinds of navigation system such as a magnetic field type, an optical and hybrid (optical+magnetic field) type navigation system.
     In our department, StealthStation S7 of a hybrid form is used by the “magnetic field type” by most cases.
      By carrying out comparison navigation systems, it is thought that we can choose the best selection of the navigation system type before an operation.
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  • Nozomu Matsumoto, Masamichi Oka, Misaki Jinnouchi, Riichi Ouchida, Shi ...
    2013Volume 56Issue 5 Pages 291-293
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     We introduce our reference antenna for image-guided temporal bone surgery. Our reference antenna was fixed to the tailor-made splint for each patient. The splint secured the accuracy as well as stability throughout the surgery for at least 4 hours. The splint-fixed reference frame was a useful in image-guided temporal bone surgery where invasive head clamp is not always practical.
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  • Masamichi Oka, Nozomu Matsumoto, Byunghyun Cho, Riichi Ouchida, Misaki ...
    2013Volume 56Issue 5 Pages 293-295
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     We introduce our IGS reference frame for easy and rapid registration. we produced dentally affixed reference frame tailored for each patient. This reference frame is detachable and has both fiducial markers and reference markers. So, by taking patient's CT scans with this reference frame, we can finish the registration without patient, before surgery. The only preparation for IGS in the operating room is to attach the reference frame on the patient again. This dentally affixed reference frame is suitable for image guided ENT surgery where invasive or time-consuming registration method is unmatched.
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese]
    2013Volume 56Issue 5 Pages 295
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
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  • Toshiki Utsunomiya, Mikiya Asako, Hisashi Ooka, Kazuyasu Baba, Hideyuk ...
    2013Volume 56Issue 5 Pages 296-299
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Control of bleeding is mentioned as an important factor which influences the success or failure of ESS. Within a narrow nasal cavity, a conventional bayonet type bipolar often is difficult to even open the tip by interference. In ESS, the mono-body forceps type tools are very useful. In recent years, many very user-friendly instruments, such as a forceps type bipolar with suction and rotation tip bipolar for skull base surgery, have already been released.
     The endoscopic surgery in a nose is expanded even to not only ESS but the nose sinonasal tumor operation, or the skull base operation in recent years, and an exact arrest of hemorrhage is an important point of an operation.
     It is also important to gather information in various surgical tools and to choose suitable tools.
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  • ―IN USE EXPERIENCE FOR MAXILLARY SINUS MYCETOMA―
    Kiyoshi Doi, Ken-ichi Nibu
    2013Volume 56Issue 5 Pages 300-302
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Biofilm and Fungi can develop sinusitis refractory to medical treatments, and Hydrodebrider System is invented for these problems. Its powerful irrigation and good flexibility helps us to remove the bacterial infection that causes ongoing sinus problem. At the present we use this system for treating fungus mycetoma. It is useful of complete removing fungus ball that is likely to be persistent in the blind spot of sinuses.
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  • Michiro Fujisaka, Hirohiko Tachino, Akira Naruse, Hiroshi Nishida, Hid ...
    2013Volume 56Issue 5 Pages 303-305
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     We described the 2 cases with fungal sinusitis. To treat these cases, we did endoscopic sinus surgery with hydrodebrider system. This system has a powerful irrigation and remove the persistent bacterial and fungal infection that causes refractory paranasal sinusitis. We used the standard handpiece to the patient with maxillary sinusitis and used the frontal handpiece to the patient with sphenoidal sinusitis. It is thought that hydrodebrider sysyem is very useful for the patient with fungal sinusitis.
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    2013Volume 56Issue 5 Pages 305
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
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  • Makoto Hashimoto, Takefumi Mikuriya, Yohei Yamamoto, Hirotaka Hara, Hi ...
    2013Volume 56Issue 5 Pages 306-307
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     We constructed the CT/MRI image fusion by the OsiriX software in paranasal sinus diseases. It was considered a useful method for preoperative and intraoperative planning.
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  • Hirotaka Hara, Makoto Hashimoto, Hiroshi Yamashita
    2013Volume 56Issue 5 Pages 308-310
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Upper airway collapse several areas in varying degrees, especially during sleep. It has been reported that the imaging results while awake do not necessarily reflect conditions during sleep, when tone of the upper airway dilating muscles is decreased. Then we should evaluate the upper airway morphology both static and dynamic manner, especially when we plan the sleep surgery.
     We have been performed 3D-CT examination as a static evaluation.
     Also, with DICOM data, we have been examined the inspiratory airflow simulation with computational fluid dynamics software (Phoenics).
     In this paper, we showed that the usefulness of the inspiratory airflow simulation with computational fluid dynamics software.
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  • Hideyuki Murata, Kazuyasu Baba, Koichi Tomoda
    2013Volume 56Issue 5 Pages 311-313
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Recently the need to produce surgical simulators has become gradually important. In this background, we reported on the education of the laryngeal surgery and treatment using a simulator which is originally used for intubation's training. The concept of surgical education has changed from the see one, do one, teach one approach to the see one, practice many, do one, and teach one approach. This means that it is important for trainee surgeons to acquire basic skills outside of the operating room before participating in procedures on patients. In this paper, we also described the importance of the training of the microlaryngeal surgery and removal of the pharyngeal foreign body using the simulator.
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  • Hideaki Takanobu
    2013Volume 56Issue 5 Pages 314-315
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     This paper describes a patient-robot and a humanoid robot that physically grows like human.
     Recently, the number of people of dentists increases every year. However, the lack of skill of graduates of schools of dentistry is obvious. The problem seems to lie in the fact that the dentists have no sufficient experience of treating human patients. The present study was made in order to develop a patient-robot for use in an actual clinical training. The patient has the possibility of making an unexpected motion while treating. This motion often surprises the dentist. Therefore, it is important to develop a whole body patient-robot.
     Human grows mentally and physically. This research, aims at reproducing the human physical growth and walking sequence by using physical models. It introduces a growth process of body parameter by physical models and the human walking motion. Growth processes of these models are reproduced using from the average measurement of multiple human data.
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  • [in Japanese]
    2013Volume 56Issue 5 Pages 315-316
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
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  • Yasushi Fujimoto, Takashi Maruo, Tsutomu Nakashima
    2013Volume 56Issue 5 Pages 316-319
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     The high-resolution, magnified, three-dimensional view of the operative field provided by TORS allows for excellent visualization of the target anatomy. The surgeon's fine hand and finger movements are translated into precise motion-scaled movement of the robotic instruments within the narrow confines of the upper aerodigestive tract. TORS radical tonsillectomy has increased the indications for transoral resection. Additional advantages of TORS procedures may include a low rate of gastrostomy tube dependence, indicative of preservation of swallowing function. High rates of negative surgical margins have been reported, which correlate well with local disease control.
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  • ―EXPERIENCE OF ATTENDING TORS ADVANCED COURSE―
    Ichiro Tateya, Seiji Ishikawa, Shigeru Hirano, Morimasa Kitamura, Tats ...
    2013Volume 56Issue 5 Pages 319-323
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Transoral robotic surgery (TORS) was developed by Weinstein as a minimally invasive surgery mainly for laryngo-pharyngeal cancer. Da Vinci surgical system is a robot which enables to perform surgery safely and precisely under 3D vision. Since TORS had been cleared by FDA in 2009, it has been spreading explosively all over the world. However, it has not been approved by Pharmaceutical and Medical Devices Agency (PMDA) in Japan. We have attended the advanced course of TORS training held in Yonsei University prior to start the clinical trial of TORS and have performed radical tonsillectomy, tongue base resection, supraglottic laryngectomy, and piriform sinus resection for a cadaver. It was easy to adapt the movement of Da Vinci and transoral anatomy was a key to perform TORS safely. PMDA approval is desired in the otolaryngological field.
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  • Hiroyuki Itoh, Akira Shimizu, Mamoru Suzuki, Nobutoshi Funato, Yasuaki ...
    2013Volume 56Issue 5 Pages 323-326
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Using the da Vinci Surgical Robot, we performed seven oropharyngeal tumor resections in a clinical study. Because transoral robotic surgery (TORS) has not been approved by our government, many problems with its performance have arisen. Performance of TORS in Japan involves an 8-mm optimal forceps, instead of 5-mm forceps. TORS was shown to be useful because the operation could be performed in 7 flexibility and multiple hand surgery. Because of these advantages, performance of tumor resections was more convenient than using the conventional method.
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  • Kei Ijichi, Daisuke Kawakita, Shingo Murakami, Megumi Harima, Hiroshi ...
    2013Volume 56Issue 5 Pages 326-329
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     In thyroid surgery, recurrent laryngeal nerve (RLN) and superior laryngeal nerve external brunch (SLNEB) is the most serious complication. Several procedures of intraoperative neuromonitoring were reported recently. We studied new RLN monitoring procedure in thyroid surgery. Airwayscope® is one of laryngoscope using in general anesthesia. Facial nerve stimulator is commonly used at parotid- and neuro-surgery. In this study, we monitored RLN and SLNEB with these two equipments. In all patients, these nerves were identified and preserved, and then, vocal cord palsy were not occurred. This monitoring method is not only easily and useful but also more cost-effective.
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  • Kazuhira Endo, Takayoshi Ueno, Akira Tsuji, Satoru Kondo, Naohiro Waki ...
    2013Volume 56Issue 5 Pages 329-331
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Sentinel lymph node navigation surgery (SNNS) would provide information to perform individualized selective neck dissection in patients with head and neck squamous cell carcinoma. We here show a technique of gamma probe localization of radiolabelled lymph nodes to identify the sentinel node in early oral cancer.
     We also report chemotherapy targeting sentinel lymph node with CDDP-incorporating polymeric micellar nanoparticle (NC-6004) in the mouse model. In an orthotopic tongue cancer model, NC-6004 reduced the rate of sentinel lymph node metastasis to lower than that with CDDP. Key words: sentinel lymph node, cisplatin, micelles
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  • Yasunao Kogashiwa, Dai Sato, Yorihisa Moro, Takehiro Nakamura, Naoyuki ...
    2013Volume 56Issue 5 Pages 332-334
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
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     In the Sentinel Node Navigation Surgery (SNNS), radioisotope method is probably the most widely used as it allows one to quantify the radioactivity picked up on the gamma probe and further to have a pre-operative picture of the identified SLN. However, this method has some problems, which was caused by using radioisotope. The aim of this study was to evaluate the clinical application of Indocyanin green (ICG) fluorescence in the mapping and detection of sentinel lymph nodes in cancers of the head and neck.
     A total of five patients with tongue or pharyngeal cancer and N0 neck status and where resection of the primary tumor was planned were used to evaluate the ICG fluorescence in the identification of the sentinel lymph node. 0.5ml of ICG solution was injected with at least four injection points along the circumference of the tumor. The infrared video camera was then directed toward the cervical area to identify the sentinel lymph node.
     In four cases the sentinel nodes could be identified, however in one case we could not detect the SN percutaneously with ICG fluorescent method. One case where identification was attempted through the skin were unsuccessful. In one case, sentinel node was pathological positive. Then the elective neck dissection was performed.
      ICG fluorescence is a potential valuable tool in the detection of SLN in patients with head and neck cancer. Further investigation is warranted.
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  • Takatsugu Mizumachi, Akihiro Homma, Tomohiro Sakashita, Satoshi Kano, ...
    2013Volume 56Issue 5 Pages 334-337
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Secondary placement of a voice prosthesis is often difficult to perform due to inability in flexing the neck after total laryngectomy and radiation therapy. We report a technique of secondary voice prosthesis placement using a curved rigid esophagoscope. An endotracheal tube and a flexible endoscope are inserted into the esophagus. In creating a tracheoesophageal puncture, a sharp forceps is inserted through the tip of esophagoscope. Then, a guide wire is introduced through the esophagoscope and the voice prosthesis is placed by back-loading method. This method is safe and easy because there is no risk of perforation through the posterior esophageal wall.
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  • Atsunobu Tsunoda, Seiji Kishimoto, Koichi Tsunoda
    2013Volume 56Issue 5 Pages 337-339
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     Using commercially available products, images including surgical findings can be recorded with higher quality. To define an appropriate folder name which include patient's name, ID, diagnosis and corresponding data, data retrieval is easily accomplished. This digital data management is useful not only in clinical use but in educational or research purpose.
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    2013Volume 56Issue 5 Pages 339
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
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  • Taku Yamashita, Masayuki Tomifuji, Koji Araki, Akihiro Shiotani
    2013Volume 56Issue 5 Pages 340-343
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
     We developed transoral videolaryngoscopic surgery (TOVS) as a minimally invasive surgical procedure for supraglottic, laryngeal, oropharyngeal, and hypopharyngeal cancers. TOVS is a novel, easy-to-use surgical procedure for transoral en bloc resection and involves use of a laryngopharyngeal retractor or distending laryngoscope, a rigid or deflectable videoendoscope, and laparoscopic surgical instruments. The advantages of this procedure are as follows. In transoral surgery, it can provide advantages similar to those of robotic surgery, such as wide field of view and working space. It is an easy procedure for otolaryngologists to perform without special training because it is an extension of well-known surgeries such as tonsillectomy or laryngomicrosurgery. Tactile sensation is retained during surgery; this is important for safe and reliable resection. Finally, this procedure can be performed at a low cost.
     Thus far, transoral oropharyngeal cancer resection using TOVS has been performed for 28 patients (29 lesions) in our institution. The resected lesions consisted of 8 T1 lesions, 14 T2 lesions, and 7 T3 lesions. There were no T4 tumors in this series. Sixteen patients (55.2%) had no nodal metastasis, while 13 patients (44.8%) were positive for nodal metastasis. Seventeen patients (58.6%) underwent neck dissection with TOVS. One patient underwent tracheotomy, and 9 (32.1%) received TOVS followed by conventional radiotherapy. None of the patients underwent reconstructive surgery. The median follow-up period in all the cases was 42 months. The 3-year crude survival rate, 3-year disease-free survival rate, and 3-year local control rate were 94.1%, 100%, and 95.5%, respectively. Postoperative swallowing function in the patients was satisfactory. TOVS for T1, T2, and some T3 oropharyngeal cancers contributed to functional preservation while maintaining cancer curability.
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    2013Volume 56Issue 5 Pages 343
    Published: October 15, 2013
    Released on J-STAGE: October 15, 2014
    JOURNAL FREE ACCESS
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