人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
8 巻, 3 号
選択された号の論文の16件中1~16を表示しています
  • 古川 俊之
    1979 年 8 巻 3 号 p. 379
    発行日: 1979/06/15
    公開日: 2011/10/07
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  • Karl E. KARLSON, Leigh R. ABTS, Robert T. BEYER, Peter D. RICHARDSON, ...
    1979 年 8 巻 3 号 p. 381-385
    発行日: 1979/06/15
    公開日: 2011/10/07
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  • 梅谷 陽二
    1979 年 8 巻 3 号 p. 386-387
    発行日: 1979/06/15
    公開日: 2011/10/07
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  • 舘 〓
    1979 年 8 巻 3 号 p. 387
    発行日: 1979/06/15
    公開日: 2011/10/07
    ジャーナル フリー
  • 土屋 喜一
    1979 年 8 巻 3 号 p. 388
    発行日: 1979/06/15
    公開日: 2011/10/07
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  • 内山 明彦
    1979 年 8 巻 3 号 p. 388a-389
    発行日: 1979/06/15
    公開日: 2011/10/07
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  • 浅井 道彦
    1979 年 8 巻 3 号 p. 389-390
    発行日: 1979/06/15
    公開日: 2011/10/07
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  • 井口 信洋
    1979 年 8 巻 3 号 p. 390
    発行日: 1979/06/15
    公開日: 2011/10/07
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  • 野一色 泰晴
    1979 年 8 巻 3 号 p. 391-395
    発行日: 1979/06/15
    公開日: 2011/10/07
    ジャーナル フリー
    Autogenous connective tissue tubes with “built-in” polyester mesh has been shown to be excellent arterial substitutes (Noishiki, 1976). In the present report, results of observation on healing process around the grafts at an early stage are presented. Examination was carried out over a period from 2 hours to 95 days after implantation of the grafts in the thoracic aortae in 31 canines.
    Under the microscope, the grafts were found to be lined initially by a thin layer of mural thrombus, which turned into a layer of fibrin with platalets and leucocytes within 1 day. Fibroblasts were observed in the fibrin layer after 2 days, and capillaries appeared penetrating the layer to connect blood vessels in surrounding tissue and the lumen of the graft after 4 days. One week later, numerous mouths of the capillaries were observed at a number of different places of the graft carrying endothelium. Discrete islands of endothelium were observed at a number of different places over inner surface of the graft two weeks after the implantation. Each island had one or more mouths of blood vessels. The endothelial lining of the inner wall was completed within 10 weeks.
    The above observation indicates that the grafts have a high ability of healing and that endothelial lining on the grafts develops not only from the adjacent endothelium of the aorta but also from islands of the endothelium which appear to pass through the layer of fibrin from the connective tissue of the grafts.
  • 大内 博, 佐々木 久雄, 横堀 寿光, 横堀 武夫, 斎藤 武雄, 前山 俊秀, 大熊 恒郎, 葛西 森夫
    1979 年 8 巻 3 号 p. 396-401
    発行日: 1979/06/15
    公開日: 2011/10/07
    ジャーナル フリー
    New experimental apparatus has been developed simulated of wind-kessel theory as a elastic model of arterial system. That is, the relation of the repeating frequency, the amount of flow, resistance of valve and the compliance of the specimen, to maximum pressure, minimum pressure and the pressure difference in this developed apparatus was experimentally proved to be similar to the relation of the cardiac frequency, cardiac output, peripheral resistance and the compliance of artery, to systolic pressure, diastolic pressure and pulse pressure in artery system, respectively.
    Using this apparatus, the characteristics of water leakage through the vascular substitute of woven Tetron was studied under pulsating, constant and combined pulsating and constant pressure, respectively.
    These experimental results show non-steady effect of water, say, pulsatiled pressure, is significant factor of leakage characteristics from vascular substitute. Some other effects are also studied. Furthermore hydrodynamical model of leakage characteristics has been proposed and shown in good agreement with experimental characteristics.
  • とくにHaemonetics Cell Saverによる検討
    萩原 秀男, 宮本 晃, 矢ケ崎 千良, 田野 井均, 隈部 時雄, 伊良子 光正, 瀬在 幸安
    1979 年 8 巻 3 号 p. 402-406
    発行日: 1979/06/15
    公開日: 2011/10/07
    ジャーナル フリー
    Recently, there has been an increase in the number of open-heart surgery, particulary of coronary artery bypass procedure. The amount of blood for the support of cardiac bypass surgery has been much more required.
    In 30 patients who underwent open-heart surgery from September 1976, the Haemonetics Cell Saver was used for hems concentration of the extracorpareal perfusate. The concentrate blood was divided into two group, washed group with saline salution (the 22 patient's blood) and non-washed group (the 6 patient's blood).
    Following tests were performed on each case; hemoglobin, hematocrit, platelet counts, fibrinogen concentration, total serum protein, red cell resistance, partial thromboplastine time, prothrombine time and electrolytes (Na, K, Ca, Mg). Platelet count, fibrinogen concentration and total serum protein were more remained in group II than in group I. Both serum Ca and Mg showed no difference.
    13 patients received transfusion of concentrated in ICU.
    Postoperative bleeding through thoracic drain was less in group II than in group I.
  • 国産ポリエステル繊維の医用材料への設計指針
    野一色 泰晴
    1979 年 8 巻 3 号 p. 407-409
    発行日: 1979/06/15
    公開日: 2011/10/07
    ジャーナル フリー
    Polyester fibers made in Japan (Tetron) were evaluated for medical use on a study in experimental animals. Vascular prostheses made of Tetron cloth (5.7cm long and 8mm in internal diameter) were prepared. These prostheses were immersed in 100% ethanol for 2 days and were washed in denser solution using ultrasonic washing machine, and then were rinsed in distilled water. These washed prostheses were implanted in the thoracic aortae of 39 dogs. The prostheses were removed from 1 to 46 weeks after implantation. As the control, the original prostheses, which were not washed, were implanted in 106 dogs. As another control, Dacron (polyester fibers made in U.S.A.) vascular prostheses were used in 146 dogs.
    Under the light microscopic observation, a slight degree of foreign body reaction against Tetron fibers was demonstrated in the tested group, while severe reaction was in the control, unwashed Tetron prostheses, and minimum reaction was in the other control, Dacron prostheses.
    These results indicate that, compared with Dacron fibers, Tetron fibers are not suitable for medical use and that the foreign body reaction against Tetron fibers is mainly caused by the adhered substances on the fibers.
    By means of electron microscopy and electron probe X-Ray microanalysis, titanium, silicone, phosphorus, iron, zinc and calcium were detected in both Tetron and Dacron fibers, but it has not yet determined whether or not they also cause the foreign body reaction.
  • PSP試験15分値による観察
    坂部 秀文, 前田 米造, 宇賀 四郎, 中村 昭光, 佐々木 義孝, 玉利 公正, 和田 行雄, 内藤 和世, 嶋田 秀逸, 越智 真一, ...
    1979 年 8 巻 3 号 p. 410-412
    発行日: 1979/06/15
    公開日: 2011/10/07
    ジャーナル フリー
    Renal function in 36 patients under long-term pacing (average 35.2 mos) was examined by the phenolsulfonphthalein test. These patients were divided into 4 groups depending on the values of PSP at 15 min.
    At initial pacing 19 patients had a value of 25%. After long-term pacing 13 of them still showed values over 25% (group A). In the remaining 6 patients the value had decreased (group B).
    Seventeen patients had values under 25% at initial pacing. After long-term pacing 7 had values over 25% (group C), and 10 patients still had values under 25% (group D).
    With improved cardiac function just after pacing, the values in group A were maintained, but in group B the values during long-term pacing declined due to aging and complications such as arteriosclerotic changes, diabetes mellitus, hypertention, and the like.
    Long-term pacing in group C improved cardiac function, causing an increase in renal plasma flow, resulting in improved the values after a few months.
    Most patients in group D have some degree of renal disturbance. Therefore the 15 min value of PSP test was low.
  • 相沢 義房, 柴田 昭, 鈴木 正司, 酒井 信治, 平沢 由平, 上村旭 旭
    1979 年 8 巻 3 号 p. 413-416
    発行日: 1979/06/15
    公開日: 2011/10/07
    ジャーナル フリー
    Some hemodialytic procedure, especially ultrafiltration or hemofiltration, is known to show a circulatory stability during hemodialysis. Dynamics of fluid exchanges was treated mathematically to see factors which may affect the hemodynamic stability. The circulating blood volume is apparently determined by the balance between the removal rate of fluid at dialyser and the capillary refilling rate in the microcirculation. The latter is described by Starling's law. The solutes are driven by Fick's law. Upon the assumption that the circulatory system is stable as long as the circulating blood volume is above certain critical value, it was shown that not only the removal rate of fluid but also the osmolality change created at the dialyser during the passage of blood will possibly affect the stability. This drop seems, therefore, the one reason of the difference found in the circulatory complication in several methods of hemodialysis and seems compatible with the result showing the importance of plasma osmolality to prevent the complication.
  • 藤田 毅
    1979 年 8 巻 3 号 p. 417-418
    発行日: 1979/06/15
    公開日: 2011/10/07
    ジャーナル フリー
  • 堀内 藤吾, 堀 原一
    1979 年 8 巻 3 号 p. 419-421
    発行日: 1979/06/15
    公開日: 2011/10/07
    ジャーナル フリー
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