Hemorrhage is one of the most troublesome complications encountered after the needle biopsy of parenchymatous organs. The situation would be the most serious to the patients maintained on hemodialysis, because they are repeatedly heparinized. To overcome the difficulty, a new technique has been contrived with the use of plastic adhesives. The materials and procedure are as follows; 1) Parenchymatous organs are biopsied using Vim-Silverman needle with an external tube for guide (Teflon). 2) After biopsy, only the Vim-Silverman needle is removed leaving the external tube in place. 3) Inserting an internal tube for injection through the external tube, iso-butyl or ethyl cyanoacrylate is applied into the bleeding point. This procedure was found to be effective in stanching oozing blood from parenchymatous organs such as kidney, liver, spleen, and pancreas. As for efficacy of the two adhesives used, there was little difference when applied to normal animals, however, iso-butyl cyanoacrylate was found superior to ethyl cyanoacrylate under heparinized condition.
Telemetry monitoring of the arteriovenous shunt far long term hemodialysis was divised. Analysis of the A-V shunt bruit picked up at the proximal surface of the burried venous cannula revealed maximum intensity of the sound at 200c/s. The newly designed air-transmission type microphone with optimum frequency at 200c/s picked up the A-V shunt bruit which was modulated into FM wave at 76MHz. Then, the signals were transmitted by the miniature FM transmitter inside the pocket of the patient. After receiving the signals by the FM receiver locating inside the nurse station, the amplified signals were selected with the band-pass filter(230±10c/s)and were half wave rectified. Then, the signals were averaged for 10 seconds by the averaging circuit. Warning alarm was given when the blood-flow inside the A-V shunt (hence the signals)ceased more than 10 seconds. This A-V shunt monitoring system was applied satisfactorily both on experimental and clinical trials for last one year. The multi-channel monitoring system and the all-pocketable direct A-Vshunt monitoring system are being planned.