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Volume 11 (1961)
- Issue 6 Pages 383-
- Issue 5 Pages 309-
- Issue 4 Pages 236-
- Issue 3 Pages 154-
- Issue 2 Pages 80-
- Issue 1 Pages 1-
Volume 11, Issue 3
Displaying 1-8 of 8 articles from this issue
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[in Japanese]1961 Volume 11 Issue 3 Pages 154-160
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSDownload PDF (1331K) -
Ikuo Higuchi1961 Volume 11 Issue 3 Pages 185-195
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSThe author carried out tissue culture of synovial tissue from the knee joint of normal adult rabbit with the following results :
1) Five nutrient media were used, out of which, a medium, consisted of horse serum 60% and Gey's solution 40%, gave the best rate of proliferation. With decrease of horse serum in synthetic medium, the rate of proliferation and numbers of polygonal and round cells tended to decrease, while spindle-shaped cells tended to increase.
2) In a period between the 3rd and 5th day of culture, remarkable difference in the rate of proliferation was observed between synovial and subsynovial tissue, the latter being greatly delayed. From the 5th to 6the day, however, the rate of proliferation in the latter markedly increased. This is considered to suggest the metaplasia of subsynovial cells into synovial cells.
3) Synovial tissue secured from different parts of the same joint did not show any remarkable difference in the rate of proliferation and proportion of various kinds of cell in tissue culture.
4) Synovial cells were grown on a medium consisting of a limited number of chemically defined compounds, supplemented witd 5% of dialyzed horse serum. On such a medium, thirteen amino acid proved to be essential for growth (Arginine, Cystine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Phneylalanine, Serine, Threonine, Tyrptophan, Tyrosine, and Valine), and six proved nonessential (Alanine, Asparaginic acid, Cysteine, Glutamic acid, Glycine, and Proline).View full abstractDownload PDF (7521K) -
THE EFFECT OF SPLENECTOMY IN THE INFECTION AND IMMUNITYTadac Honda, Hajime Hashimoto, Tadashi Nakano, Tetsuo Wakao1961 Volume 11 Issue 3 Pages 202-206
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSSplenectomized and cortrol mice were infected with an atenuated strain or a virulent strain of S. enteriridis. There was no difference in both the distribution of infected microorganisms and the growth of them in the sensitive organs.
After mice received the operation of splenectomy, they were immunized with living or killed vaccine, and 2 weeks later, they were challenged with a virulent strain of S. enteritidis.
In normal and splenectomized mice, it was found no difference in the survival rate and the clea rance of challenged microorganisms in the infected organs.
In the antibody formation, the splenectomized mice showed lower O and OH titer than normal mice.View full abstractDownload PDF (633K) -
Kyoko Omura, Sadayuki F. Takagi, Osamu Harada1961 Volume 11 Issue 3 Pages 207-215
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSIt is well known that naramysin, cyclohexiimid has a strong repellent action to the rat. It was intended to clarify which one of the two conceivable stimuli, the smell and the taste of the drug does a rat detest. It was concluded that the evasion of a rat to naramysin primarily originates in the taste of the drug, but once a rat experiences the detestable taste, it remembers the smell which works as a conditioning stimulus thereafter.View full abstractDownload PDF (1272K) -
Shoji Hoshi, Manabu Homma, Kenzaburo Suto, Takashi Okonogi1961 Volume 11 Issue 3 Pages 216-221
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSThc necrosis and degeneration of muscle with a hemorrhage is the most serious symptom of local pathological changes resulting from the intramuscular injection of Habu-Venom.
Among many Habu-venom-in jected experimental animals, a particular case was notable : it showed crystalline appearances which seemed to be formed of the degenerated muscular fiber.
An experimemtal animal : a guinea pia weighing 450g.
Injected intramuscularly into thc right thigh.
Venom inj. : 10mg (dry weight) /1.0ml aq. dest.
The animal died in 3 hours. The injected site swelled and softened with a violent hemorrhage.Histologically, severe necrosis, coagulation and lysis of the muscular fibers were seen. In these degenerated muscular tissues, triangle crystalline substances (10μ-150μ), which had become free, were recognized. Crystalline bodies (completely formed) were stained. : red with H-E stain, yellow with Marolly's anilline blue collagen stain, orange with Sudan III stain, dark violet with Smith-Dietrich's stain. Lepehne's hemoglobin reaction was positive.
A cyrstalloid body remained in the coagulated muscular fiber when the formation was not complete : some still held the myofibrillen in the crystalloid body.
Among many experimental animals that received the intramuscular injection of Habu-vcnom, only one case demonstrated such an interesting phenomenon.View full abstractDownload PDF (1789K) -
Shinichi Minowa, Hirouchi Takahashi, Tarô Kodama, Takeshi Kano1961 Volume 11 Issue 3 Pages 222-227
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSComparative investigations were performed on 200 cases of various infectious diseases, recently treated, for resistances of different pathogenic bacteria to 7 drugs : Sulfathiazole (St), Penicillin (PC), Dehydrostreptomycin (SM), Chloramphenicol (CM), Tetracycline (TC), Erythromycin (EM), Leucomycin (LM).
As a whole, St resistance with 85% and PC resistance with 74% ranked highest, TC, EM and LM resistance ranging 4050%, were intermediate, and SM and CM resistance with about 30% were the lowest. This tendency was more or less observed in all diseases and for all bacteria.
As for difference between in-and out-patients, resistances of the former were higher than those of the latter to all the drugs by about 10-15%.
This tendency was recognized in each disease.
St, PC and EM resistance in diseases of digestive system ranged 90-100%, which were higher than in any other disease. As contrast, SM and CM resistance in oto-rhino-laryngological diseases were lowest with 0-3%. Relatively high St and PC resistance were found for Shigella dysenteriae, Escherichia coli and Pseudomonas aeruginosa, and relatively low SM and CM resistance for Gram-negative bacilli, Staphylococci and Diplococcus pneumoniae.
Multiresistance to 4 drugs (St. PC, SM and CM) with sensitivity of 8% was extremely infrequent, but those to 3 and 4 drugs with resistance of 36% were remarkably frequent.
These results were compared with reports by various other workers. and it was pointed out necessary to establish accordingly adequate therapies and counter-plans from view point of public health.View full abstractDownload PDF (999K) -
1961 Volume 11 Issue 3 Pages 228-232
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSDownload PDF (1202K) -
1961 Volume 11 Issue 3 Pages 233-235
Published: 1961
Released on J-STAGE: November 11, 2009
JOURNAL FREE ACCESSDownload PDF (607K)
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