生活衛生
Online ISSN : 1883-6631
Print ISSN : 0582-4176
ISSN-L : 0582-4176
52 巻, 1 号
選択された号の論文の4件中1~4を表示しています
総説
  • 市原 理子
    2008 年 52 巻 1 号 p. 3-12
    発行日: 2008年
    公開日: 2008/02/07
    ジャーナル フリー
    It is well known that steric stabilization of the surface of liposomes by a polyethyleneglycol (PEG) - conjugated lipid results in reduced recognition of the liposomes by the cells of the mononuclear phagocyte systems (MPS) and consequently extends their circulation times (t1/2 ≈ 20h in rat). Recently, we reported the “accelerated blood clearance (ABC) phenomenon”, causing PEGylated liposomes (sterically stabilized liposomes, SL) to be cleared very rapidly from the circulation upon repeated injections. Our study suggested that the selective binding of IgM, induced by the first dose of SL, to the second dose of SL and the subsequent complement activation by IgM resulted in accelerated clearance of the second dose. The present paper describes the mechanism of the ABC phenomenon in terms of its interaction with biological factors.
報文
  • 宮崎 竹二, 船坂 邦弘, 神浦 俊一, 山本 攻
    2008 年 52 巻 1 号 p. 13-25
    発行日: 2008年
    公開日: 2008/02/07
    ジャーナル フリー
    Outdoor and indoor SPM concentrations at roadside and roadside-vicinity dwellings were measured at three sites in Osaka City with differing traffic volumes over the nine years from 1996 to 2004. The sampling seasons were summer, autumn and winter, in each of which the duration of window opening was different. The correlation coefficient between outdoor and indoor SPM concentrations in non-smoking homes was 0.804 for PM2.5 and 0.811 for PM10. It was confirmed that indoor SPM concentration is significantly affected by outdoor SPM concentration.
    Outdoor and indoor PM2.5 concentrations at roadside dwellings were 33.3μg/m3 and 24.0μg/m3 respectively. The corresponding levels at roadside-vicinity dwellings were 24.7μg/m3 and 19.9μg/m3 respectively. Although the difference in indoor PM2.5 concentrations between roadside and roadside-vicinity dwellings (4.1μg/m3) was smaller than the difference in outdoor PM2.5 concentrations (8.6μg/m3), the considerably higher indoor PM2.5 concentration values for roadside dwellings were thought to be due to automobile exhaust.
    Predicted personal exposure PM2.5 concentrations of roadside and roadside-vicinity residents, calculated for time spent 80% indoors and 20% outdoors, were 25.9μg/m3 and 20.8μg/m3 respectively; the difference in these values was 5.1μg/m3.
資料
  • 杉森 英里, 為定 誠, 坂上 吉一
    2008 年 52 巻 1 号 p. 26-32
    発行日: 2008年
    公開日: 2008/02/07
    ジャーナル フリー
    In recent years, consumers have become increasingly aware of bacterial eradication in household laundering. As a result, a number of laundry detergents carry the indication “For bacterial eradication” on their packages. We attempted to evaluate the bacterial eradication effect of laundry detergents and bactericidal products and explored relevant study designs. It was found that washing test apparatuses, test clothes and methods for evaluating washing ability have already been set as part of the test for color fastness against washing (JIS L0844) and the test for synthetic detergents (JIS K3362). However, it was also found that a specified washing test apparatus would be necessary to perform the recommended microbial test and that considerable time and effort would be needed to prepare the contaminated clothes (JIS C9606 Annex 4 and artificially contaminated wet cloth of the Laundry Science Association). We therefore explored methods at laboratory level to develop a simpler bacterial eradication test for washing.
    We evaluated ordinary laundry detergents marketed by detergent manufacturers and those labeled “For bacterial eradication” and also investigated the effect of bactericidal products with silver content.
    It was found that Staphylococcus aureus, a Gram-positive coccus, was eradicated more satisfactorily by the laundry soaps labeled “For bacterial eradication” than ordinary laundry soaps. In contrast, Pseudomonas aeruginosa, a Gram-negative bacillus, showed no difference in eradication level between the two types. Bactericidal washing products containing silver showed sufficient bactericidal effect against both species. We conclude that these findings have established basic considerations for the standardization of bacterial eradication testing of detergents.
  • 芳倉 太郎, 西尾 孝之, 藤原 康博
    2008 年 52 巻 1 号 p. 33-43
    発行日: 2008年
    公開日: 2008/02/07
    ジャーナル フリー
    The present document summarizes the achievements of Osaka City Institute of Public Health and Environmental Sciences in the study of leachate control and management at a sea-based solid waste disposal sites in Osaka City.
    The document covers investigative research such as analysis of changes in water quality, advanced water treatment for the removal of nitrogen and micropollutans, water treatment using activated charcoal made from wastewood, and microbiological study.
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